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2results about How to "Reduce endotoxin" patented technology

Drug carrier based on N-acetylglucosamine, drug preparation and preparation method

PendingCN121818943AQuick point releaseReduce endotoxinPharmaceutical non-active ingredientsGranular deliveryDrug release rateKetone
The invention provides a drug carrier based on N-acetylglucosamine, a drug preparation and a preparation method. The drug carrier based on N-acetylglucosamine comprises N-acetylglucosamine and a cross-linking agent, the cross-linking agent is a compound with an aldehyde group or a ketone group, and the aldehyde group or the ketone group reacts with the deacetylated N-acetylglucosamine to generate one or more of a hydrazide bond, a hydrazone bond or an imine bond. The drug carrier based on N-acetylglucosamine shows remarkable advantages in the aspects of particle size distribution, drug loading capacity, encapsulation efficiency and cumulative drug release rate.
Owner:QINHUANGDAO BOHAI RIM BIOLOGICAL IND RES INST BEIJING UNIV OF CHEM TECH +1