Application of aminoglycoside antibiotic in preparing pharmaceutical composition for treating drug-fast bacteria infection
A technology of aminoglycosides and antibiotics, applied in sugar derivatives, antibacterial drugs, drug delivery, etc., can solve problems such as not being able to cover the invention concept, and achieve good antibacterial and antibacterial effects
Active Publication Date: 2010-09-08
CHANGZHOU FANGYUAN PHARMA
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Therefore, the above-mentioned patent documents cannot cover the inventive concept of this patent
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The invention provies an application of an aminoglycoside antibiotic in preparing drug combination to treat drug-resistant bacteria infection, belonging to the aminoglycoside antibiotic application technical field. The invention provides the application method of 2'-NH2-3',4'-dideoxy aminoglycoside antibiotic1-N-acyl derivatives and the preparation methods of the derivatives and agentsof the product.
Description
technical field The application of an aminoglycoside antibiotic in the preparation of a pharmaceutical composition for treating drug-resistant bacterial infection belongs to the technical field of aminoglycoside antibiotic application. The present invention relates to having 2'-NH 2 1-N-acylated derivatives of aminoglycoside antibiotics with 3', 4'-dideoxy structures and their application in the preparation of pharmaceutical compositions against drug-resistant bacteria. Background technique Document 1CN1420120A, Document 2ZL93112412.3, Document 3ZL01133701.X, Document 4USP4117221, Document 5USP4230847, Document 6USP5442047. Since the listing of aminoglycoside antibiotics, their broad-spectrum antibacterial activity, especially against Gram-negative bacteria, has a good synergistic effect with β-lactam antibiotics widely used in clinical practice and their main otic , Renal toxicity is predictable, thus becoming an indispensable class of antibiotics in clinical p...
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IPC IPC(8): A61K31/7036A61K9/00A61K9/08A61K9/12A61K9/20A61P31/04C07H15/226
CPCA61K31/7036A61P31/04
Inventor 刘军
Owner CHANGZHOU FANGYUAN PHARMA
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