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Composition with lactogenic effect and preparation method and application thereof

The technology of a composition and angelica, applied in the field of compositions with prolactin action, can solve the problems of large side effects, unsuitable for routine use, easy to cause allergic reactions and the like

Inactive Publication Date: 2013-03-27
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although folk diet therapy is relatively common, its efficacy is uncertain, lacks scientific research support, and can easily cause allergic reactions
Acupuncture, massage, and medical equipment-assisted therapy are mostly auxiliary and should not be used routinely
In drug treatment, Western medicine lacks effective and targeted drugs in the treatment of postpartum hypogalactia, and often has relatively large side effects. Therefore, the current clinical medication is mainly based on traditional Chinese medicine prescriptions, decoction treatment, and patients feel pain when taking medicine. not good
In addition, pangolin, an animal medicinal material, is added to the prescriptions of domestically approved prolactin-promoting Chinese patent medicines such as Tongru Granules and Xiaruyongquan San. However, pangolin is a national second-class precious and protected animal, which cannot meet the needs of clinical medicine.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0080] Angelica 3kg, Chuanxiong 1.8kg, peach kernel 1.2kg, dried ginger 0.6kg, astragalus 3kg, bellflower 0.9kg, roasted licorice 0.6kg, a total of 11.1kg

[0081] Specific process: the above seven flavors, angelica, chuanxiong, and dried ginger are extracted twice with 8 times the amount of 70% ethanol, extracted for 2 hours and 1 hour respectively, and the extracts are combined and ethanol is recovered to obtain a concentrated solution. Add 8 times the amount of water to extract the rest of the medicinal flavors twice, each time for 2 hours, combine and concentrate the second decoction until the relative density reaches 1.05-1.20 (80°C), add ethanol to make the alcohol content reach 65%, let stand, filter, and take Ethanol is recovered from the supernatant, combined with the ethanol extract, concentrated and collected to obtain the ointment.

Embodiment 2

[0083] Angelica 5kg, Chuanxiong 3kg, peach kernel 2kg, dried ginger 0.5kg, astragalus 5kg, bellflower 1kg, roasted licorice 0.5kg, a total of 17kg. Specific process: the above seven flavors, angelica, chuanxiong, and dried ginger are extracted 3 times with 10 times the amount of 70% ethanol, extracted for 1 hour, 1 hour, and 1 hour respectively, and the extracts are combined and ethanol is recovered to obtain a concentrated solution. Add 10 times the amount of water to extract the rest of the herbs for 3 times, 1.5 hours each time, combine and concentrate the three decoctions until the relative density reaches 1.05-1.20 (80°C), add ethanol to make the alcohol content reach 75%, let stand, filter, and take Ethanol is recovered from the supernatant, combined with the ethanol extract, concentrated and collected to obtain the ointment.

Embodiment 3

[0085] Angelica 1kg, Chuanxiong 0.4kg, peach kernel 0.4kg, dried ginger 0.2kg, astragalus 1kg, bellflower 0.2kg, roasted licorice 0.2kg, a total of 3.4kg.

[0086] Specific process: the above seven flavors, angelica, chuanxiong, and dried ginger are extracted 3 times with 6 times the amount of 50% ethanol, extracted for 1 hour, 1 hour, and 1 hour respectively, and the extracts are combined and ethanol is recovered to obtain a concentrated solution. Add 6 times the amount of water to extract the rest of the herbs twice, each time for 3 hours, combine and concentrate the second decoction until the relative density reaches 1.05-1.20 (80°C), add ethanol to make the alcohol content reach 65%, let stand, filter, and take Ethanol is recovered from the supernatant, combined with the ethanol extract, concentrated and collected to obtain the ointment.

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PUM

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Abstract

The invention discloses a composition with lactogenic effect and a preparation method and application thereof. The composition consists of the following components in part by weight: 5 to 25 parts of Chinese angelica, 3 to 12 parts of Szechuan lovage rhizome, 2 to 6 parts of peach seed, 0.5 to 4 parts of blast-fried dried ginger, 5 to 20 parts of astragalus root, 1 to 6 parts of platycodon root and 0.5 to 4 parts of mix-fried licorice. The composition can remarkably increase the milk secretion quantity of milk lacking female mice, and can remarkably increase the serum prolactin content and hypothalamus 5-hydroxytryptamine content of the milk lacking animals so that the mammary tissues are in a high milk secretion state.

Description

technical field [0001] The invention relates to the fields of medicine and health food, in particular to a composition with prolactin effect. Background technique [0002] Since the 1970s, a large number of scientific studies have confirmed the incomparable superiority of breastfeeding. Breast milk is the safest and most scientific natural food for babies. It not only provides basic nutrition for babies to survive, but also has no pollution. It can increase babies' immunity, prevent babies from diseases, and protect their healthy physical and mental development; Breastfeeding can provide loving communication and promote good brain development; breastfeeding ensures frequent interaction, exposes infants to language, positive social behavior and obvious stimulation, enhances infant intelligence and increases mother-child bonding; breastfeeding It can also reduce the mother's risk of breast cancer and ovarian cancer, reduce postpartum hemorrhage, delay ovulation, and naturally...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61P15/14A23L1/29A23L33/00
Inventor 朱永宏周水平颜璐璐周杜荣周王谊万梅绪王根辈马晓慧
Owner TIANJIN TASLY PHARMA CO LTD
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