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A registration-based reconstruction method for intermediate phase images of lung 4d-ct images during inspiration

A 4D-CT and phase image technology, applied in the field of medical image processing, can solve problems such as the impact of CT image quality, achieve important application value, and reduce the effect of imaging radiation dose

Inactive Publication Date: 2018-04-27
SOUTHERN MEDICAL UNIVERSITY
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Problems solved by technology

In addition, whether the real-time phase processing system (RPM) is accurately synchronized with the scanning equipment will also have a greater impact on the quality of the acquired CT images

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  • A registration-based reconstruction method for intermediate phase images of lung 4d-ct images during inspiration
  • A registration-based reconstruction method for intermediate phase images of lung 4d-ct images during inspiration
  • A registration-based reconstruction method for intermediate phase images of lung 4d-ct images during inspiration

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Embodiment Construction

[0051] like image 3 As shown, the present invention is based on the reconstruction method of the intermediate phase image of the lung 4D-CT image inspiratory process of registration, comprising the following steps:

[0052] (1) Obtain lung 3D-CT images with phase 5 and phase 9 from the lung 4D-CT image data, phase 5 is the end-expiratory phase, and phase 9 is the end-inspiratory phase;

[0053] (2) Select the 5-phase image as the reference image, and the 9-phase image as the floating image, register the two phase images, and estimate the motion deformation field T between the two phase images according to the Active Demons driving force expression. The specific process is as follows :

[0054] (2.1) The Active Demons registration method is an elastic registration method proposed on the basis of the optical flow field theory. The premise of this theory is that the gray value of the lung image remains unchanged during the breathing movement, namely:

[0055]I(x(t), y(t), z(t)...

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Abstract

The invention discloses a method for reconstructing an intermediate phase image of a lung 4D-CT image inspiratory process based on registration, including the step (1) obtaining the two phases of the end-expiration and end-inspiration lung 3D-CT from the lung 4D-CT image data. CT image; (2) Select the lung 3D-CT image of the end-expiratory phase as a reference image, and the lung 3D-CT image of the end-inspiratory phase as a floating image, and register the two phase images to obtain two phase images (3) Based on the motion deformation field obtained in step (2), reconstruct the intermediate phase image of the lung 4D-CT image inspiratory process. The present invention uses two known special phase images to reconstruct the intermediate phase image of the lung 4D-CT image during the inhalation process, avoiding the high absorbed dose of the lung 4D-CT data due to many acquisition phases and long scanning time shortcoming.

Description

technical field [0001] The invention relates to the technical field of medical image processing, in particular to a method for reconstructing an intermediate phase image of a lung 4D-CT image during inhalation based on registration. Background technique [0002] 4D-CT is a new technique emerging in recent years to evaluate the movement of tumors and organs. Compared with traditional 3D-CT, 4D-CT adds a time axis, which dynamically collects CT images of the patient while breathing, and then obtains 3D-CT images of the patient in different respiratory phases through image reconstruction and rearrangement. Lung 4D-CT truly reproduces the spatial structure and movement of tumors and organs, and better solves the dose error caused by motion artifacts and respiratory movement, which becomes the key to precise target positioning in radiotherapy. [0003] However, the acquisition of lung 4D-CT data usually requires the acquisition of multiple phases of 3D-CT images, which makes the...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06T15/00G06T5/50G06T3/40G06T7/30A61B6/03
Inventor 张煜耿丹丹
Owner SOUTHERN MEDICAL UNIVERSITY