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Pharmaceutical composition containing Euphorbactin and application thereof

A technology of composition and medicine, applied in the field of medicine

Inactive Publication Date: 2017-06-16
徐州诺克非医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there is no information about the effect of Euphorbactin and trilobate pteroside on enhancing the immune function of lung-qi deficiency syndrome.

Method used

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  • Pharmaceutical composition containing Euphorbactin and application thereof
  • Pharmaceutical composition containing Euphorbactin and application thereof
  • Pharmaceutical composition containing Euphorbactin and application thereof

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Experimental program
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Embodiment Construction

[0011] The above description is only an overview of the technical solution of the present invention. In order to understand the technical means of the present invention more clearly and implement it according to the content of the description and conventional technical means in the field, the animal test examples of the present invention will be further described in detail below .

[0012] Chinese name: Pteroside trilobite, CAS number: 6807-83-6, available from Chengdu Sitiande Biotechnology Co., Ltd.

[0013] For the preparation method of the compound Euphorbactin involved in the present invention, please refer to the literature: A Minor Diterpenoid with a New 6 / 5 / 7 / 3 Fused-Ring Skeleton from Euphorbia micractina, Org. Lett., 2014, 16(15), 3950-3953.

[0014] Drug efficacy test:

[0015] Modeling: clean-grade Kunming mice, male, weighing 18-22 g, the ambient temperature of the animal room is 25°C-28°C, and the humidity is 35%-45%. 220 mice were randomly divided into 22 grou...

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Abstract

The invention discloses the application of a pharmaceutical composition containing Euphorbactin in enhancing the immune function of lung-qi deficiency syndrome. The active ingredient includes Euphorbactin and trilobactin. The present invention uses Euphorbactin and pteroside in combination, and the experimental results show that Euphorbactin and pteroside have a good effect on enhancing the immune function of lung-qi deficiency syndrome.

Description

technical field [0001] The invention relates to the application of a pharmaceutical composition containing Euphorbactin in enhancing the immune function of lung-qi deficiency syndrome, and belongs to the technical field of medicine. Background technique [0002] Lung qi deficiency syndrome is a common syndrome of lung system diseases, and it is the main basic syndrome type in the study of lung system syndromes in traditional Chinese medicine. According to traditional Chinese medicine, the protective function of the lungs is manifested in the ability of the lungs to release and defend qi so that external pathogens cannot invade. Modern medicine believes that the defense function of the lung is closely related to the immune function. T lymphocytes are divided into CD4+ cells and CD8+ cells according to cell surface antigens, and divided into helper T cells (Th), suppressor T cells (Ts) and cytotoxic T cells (Tc) subgroups according to immune function. CD4+ molecules are most...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/343A61K31/7048A61P11/00A61P37/02
CPCA61K31/343A61K31/7048
Inventor 庄焕迪
Owner 徐州诺克非医药科技有限公司
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