Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Pre-frontal cortex processing disorder, gait and limb impairment treatment

A technology for limb disorders and diseases, applied in the field of drug intervention, disorders secondary to diseases or disorders, and can solve problems such as weakness and pain

Active Publication Date: 2018-05-11
GILROSE PHARMA
View PDF30 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Injectable drugs, such as interferon derivatives, especially (peginterferon beta-1a), which is known in the treatment of multiple sclerosis, and such injections can cause debilitating pain

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Pre-frontal cortex processing disorder, gait and limb impairment treatment
  • Pre-frontal cortex processing disorder, gait and limb impairment treatment
  • Pre-frontal cortex processing disorder, gait and limb impairment treatment

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0054] participant 1

[0055] Participant 1 was a male and was 8 years old when the pharmaceutical intervention of the present invention was first administered. Participant 1 had speech delay. Participant 1 was diagnosed with spastic diplegia, bilateral contractures at the hip joint. Participant 1 wore a leg brace before the drug intervention and had it removed at the initial visit. Participant 1 was treated with Botox injections, oral baclofen and orthotics before the drug intervention of the present invention. The parents of participant 1 discontinued all these treatments because they did not observe any gait improvement.

[0056] The initial drug intervention was 2 mL (10 mg) One month later it was replaced with 5 mg racemic methylphenidate (MPD / day. For participant 1 figure 1 and figure 2 Gait improvement is shown approximately 45 minutes after the initial visit and after daily treatment with 5 mg methylphenidate.

[0057] participant 2

[0058] Participant 2...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

A methylphenidate, particularly including dextro-threo-methylphenidate, is administered to a subject to treat a gait or limb impairment secondary to a genetically acquired pre-frontal cortex processing disease or disorder, particularly including multiple sclerosis, cerebral palsy, Angelman syndrome, Rett syndrome and Fragile-X syndrome.

Description

[0001] previous related applications [0002] This application is a PCT application of U.S. Serial No. 14 / 793,829, filed July 8, 2015, now US 9,307,942, and also claims priority to U.S. Serial No. 14 / 971,325, filed December 16, 2015, now Serial No. _____, which is a divisional application of the above-mentioned U.S. Serial No. 14 / 793,829, filed July 8, 2015, now US9,307,942, and also claims U.S. Serial No. 15, filed March 21, 2016 / 075,375, which is a continuation-in-part of the aforementioned U.S. Serial No. 14 / 971,325, filed December 16, 2015, and also claims U.S. Serial No. 14 / 881,516, filed October 13, 2015, now Priority to US 9,333,198, which is the aforementioned divisional application of US Serial No. 14 / 793,829, filed July 8, 2015, which applications are hereby incorporated by reference in their entirety. technical field [0003] The present invention relates to a pharmaceutical intervention and method for the treatment of gait or limb disorders, particularly includin...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K31/4458A61K45/06A61K31/454
CPCA61K45/06A61K31/4458A61K31/454A61K31/437A61P25/00A61P25/14A61K2300/00
Inventor 布鲁斯·罗斯曼基拉·卡普兰
Owner GILROSE PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com