Application of taking EPS8L2 as biomarker for indicating intrahepatic nodule and pre-warning liver cancer at early stage

Abstract

The invention relates to application of taking EPS8L2 as a biomarker for indicating an intrahepatic nodule and pre-warning liver cancer at an early stage, in particular to application of the followingreagents in preparing a kit for diagnosing the intrahepatic nodule of an object or diagnosing whether the object is in a vicious transformation critical phase from hepatitis to liver cancer, and thereagents comprise: (1) a reagent which is specifically combined with EPS8L2; (2) a reagent which is randomly selected and specifically combined with LTA4H; and (3) a reagent which is randomly selected and specifically combined with PLA2G6. The key critical stage of transformation from hepatitis to liver cancer is found based on an analysis on time sequence dynamics and network correlation, so that a novel direction is provided for clinically being applied to early-stage liver cancer treatment of a patient with hepatitis, judging whether the patient is in the critical stage of vicious transformation from hepatitis to liver cancer, and preventing deterioration of hepatitis and liver cancer.

Description

technical field [0001] The present invention relates to EPS8L2 as a biomarker for indicating intrahepatic nodules and early warning of liver cancer. Background technique [0002] Liver cancer, as one of the most life-threatening malignant tumors, has attracted worldwide attention. According to the global cancer statistics report, liver cancer has become the cancer with the highest incidence rate in China, and the rampant hepatitis virus has made China the hardest hit area for hepatitis and liver cancer. Therefore, how to effectively prevent the deterioration of hepatitis to liver cancer has become one of the important topics for domestic researchers. [0003] Recently, studies have shown that chronic inflammation can indeed induce the occurrence of various cancers, including liver cancer. Although researchers have put forward many hypotheses about the mechanism of inflammation promoting cancer, the mechanism of malignant transformation from chronic hepatitis to liver cance...

AI Technical Summary

Problems solved by technology

However, these diagnostic methods have drawbacks. On the one hand, the disease is extremely serious and the tumor has grown large enough to be distinguished by medical imaging equipment;

These diagnostic deficiencies seriously affect the understanding of the disease and thus affect the quality and effectiveness of treatment

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