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Photothermal therapy method, system and industrial computer based on terahertz imaging

A technology of terahertz imaging and photothermal therapy, which is applied in the fields of treatment, radiation therapy, and diagnosis by using light. It can solve the problems of high cost, image monitoring and treatment, and easy introduction of external interference factors, etc., and achieves simple structure and synergistic effect Good results

Active Publication Date: 2021-06-15
SHENZHEN INST OF TERAHERTZ TECH & INNOVATION CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In view of this, the embodiment of the present invention provides a photothermal therapy method, system and industrial computer based on terahertz imaging to solve the problem that the existing photothermal therapy technology cannot simultaneously perform targeted identification, image monitoring and treatment of tumors. Poor synergy, complex structure, high cost, and easy introduction of external interference factors make it difficult to meet the needs of efficient, accurate, and multi-functional practical applications

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  • Photothermal therapy method, system and industrial computer based on terahertz imaging
  • Photothermal therapy method, system and industrial computer based on terahertz imaging
  • Photothermal therapy method, system and industrial computer based on terahertz imaging

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Embodiment 1

[0037] Such as figure 1 As shown, this embodiment provides a photothermal therapy system 100 based on terahertz imaging, including an industrial computer 1 , a laser emitting mechanism 2 and an injection device 3 electrically connected to the industrial computer 1 .

[0038] In a specific application, an Industrial Personal Computer (IPC), that is, an industrial control computer, can be a conventional industrial computer, or a smart phone, a tablet computer, a personal digital assistant, a notebook computer, a desktop computer, a personal computer connected to a monitor, etc. Computing devices such as computers or servers are used as industrial computers.

[0039] In this embodiment, the laser emitting mechanism has the functions of radiating and detecting terahertz waves, and the injection device has the function of automatically injecting photothermal reagents.

[0040] Such as figure 2 shown, based on figure 1 As shown in the photothermal therapy system 100, the phototh...

Embodiment 2

[0060] Such as image 3 As shown, in this embodiment, the laser emitting mechanism 2 in Embodiment 1 includes a double pulse laser 21, a beam splitter 22, a terahertz radiator 23, a bias voltage module 24, a terahertz detector 25 and a lock-in amplifier Module 26;

[0061] The double-pulse laser 21 is electrically connected to the industrial computer 1 , the bias voltage module 24 is electrically connected to the terahertz radiator 23 and the industrial computer 1 , and the lock-in amplifier module 26 is electrically connected to the terahertz detector 25 and the industrial computer 1 .

[0062] Such as Figure 4 shown, based on image 3 In the shown photothermal therapy system 100, in this embodiment, step S201 includes:

[0063] Step S401, controlling the double-pulse laser to emit a first pulse laser; wherein, the beam splitter is used to split the first pulse laser into pump light and probe light, and the pump light is radiated to the a terahertz radiator, the detectio...

Embodiment 3

[0094] Such as Figure 7 As shown, in this embodiment, the laser emitting mechanism 2 in the second embodiment also includes an optical delay line system 27, a first off-axis parabolic mirror 28, a second off-axis parabolic mirror 29, and a focusing lens 20;

[0095] The optical delay line system 27 is electrically connected to the industrial computer 1, and is used to optically delay the pump light under the control of the industrial computer 1;

[0096] The first off-axis parabolic mirror 28 is used to focus the terahertz wave radiated by the terahertz radiator 23 to the object to be treated;

[0097] The second off-axis parabolic mirror 29 is used to focus the terahertz wave reflected by the object to be treated to the first incident surface of the terahertz detector 25;

[0098] The focusing lens 20 is used to focus the second pulsed laser light to the area to be treated.

[0099] In specific applications, the specific structures and types of the optical delay system, th...

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Abstract

The present invention is applicable to the technical field of photothermal therapy, and provides a photothermal therapy method, system and industrial computer based on terahertz imaging. The reflected terahertz wave is processed into a digital signal and a terahertz pulse signal is generated to obtain and analyze the terahertz spectrum and imaging information of the object to be treated, and to identify the area to be treated of the object to be treated; inject a preset dose into the area to be treated Photothermal reagents; radiate pulsed laser to the area to be treated for photothermal therapy and simultaneously acquire the terahertz spectrum and imaging information of the object to be treated, monitor the effect of photothermal therapy and adjust the parameters and presets of the pulsed laser according to the effect feedback The size of the dose and the duration of photothermal therapy can realize target recognition, image monitoring and treatment of the treatment area at the same time, with good synergy and no external interference factors.

Description

technical field [0001] The invention belongs to the technical field of photothermal therapy, and in particular relates to a photothermal therapy method, system and industrial computer based on terahertz imaging. Background technique [0002] Photothermal therapy technology uses near-infrared light with strong tissue penetrating ability as the energy source, and uses nanomaterials with high photothermal conversion efficiency, good biocompatibility, and low toxicity as photothermal reagents. The tumor marker recognition group is modified on the surface, and the photothermal reagent is injected into the patient's body for tumor targeting recognition and enrichment, and heat is generated under the irradiation of an energy light source, so as to achieve the purpose of targeted destruction of tumor tissue and killing cancer cells . As an emerging treatment method, photothermal therapy technology has many advantages such as high targeting, fast treatment speed, less side effects, ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61N5/067A61B5/00
CPCA61B5/0059A61N5/062A61N5/0625A61N5/067
Inventor 杨少壮李辰
Owner SHENZHEN INST OF TERAHERTZ TECH & INNOVATION CO LTD
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