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SST2-based model for evaluating prognosis of malignant tumor patient and application of sST2-based model

A technology for malignant tumors and tumor patients, applied in the field of biomedical testing, to achieve the effect of timely and effective communication between doctors and patients

Pending Publication Date: 2020-11-17
ZHONGSHAN HOSPITAL FUDAN UNIV
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Problems solved by technology

However, with the continuous deepening of the concept of precision medicine, the model of evaluating the prognosis of patients based only on tumor staging obviously has certain limitations.

Method used

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  • SST2-based model for evaluating prognosis of malignant tumor patient and application of sST2-based model
  • SST2-based model for evaluating prognosis of malignant tumor patient and application of sST2-based model
  • SST2-based model for evaluating prognosis of malignant tumor patient and application of sST2-based model

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Embodiment

[0043] The patient visited the doctor on June 1, 2020, aged 68, male. 2020-5-27 Gastric adenocarcinoma was diagnosed by gastroscopy. Pathology showed that the tumor invaded the muscularis propria. PET-CT showed perigastric lymph node metastasis and multiple liver metastases. Has not received any anti-tumor therapy. Laboratory tests were performed after admission, sST2 45ng / mL, LDH 150U / L, CRP10mg / L.

[0044] In this case, according to the 8th edition of the AJCC staging of gastric cancer, tumor invasion into the muscularis propria was judged as T2, perigastric lymph node metastasis was judged as N+, multiple liver metastases were judged as M1, comprehensive assessment: stage IV. Therefore, the data index of its risk factor is 1 point.

[0045] In this case, the onset age of the patient was 68 years old, that is, ≥65 years old, and the data index of the risk factor was 1 point.

[0046] In this case, the sST2 45ng / mL was detected before the patient received any anti-tumor th...

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Abstract

The invention relates to an sST2-based model for evaluating prognosis of a malignant tumor patient and application of the sST2-based model, and belongs to the technical field of biomedical detection.The invention provides an sST2-based model for evaluating prognosis of a malignant tumor patient. At present, prognosis of a tumor patient is mainly evaluated according to a tumor staging system, butthe evaluation mode has certain limitation. Based on sST2, a novel tumor prognosis evaluation model is formulated by integrating tumor staging, patient age and other laboratory indexes, and referenceinformation is provided for prognosis of tumor patients, so that clinicians are helped to formulate the most reasonable diagnosis and treatment plan for the tumor patients, and timely and effective doctor-patient communication is facilitated.

Description

technical field [0001] The invention relates to a sST2-based model for evaluating the prognosis of malignant tumor patients and its application, belonging to the technical field of biomedical detection. Background technique [0002] Tumor is one of the most important diseases threatening human health. Although the diagnosis and treatment of tumors has been developed rapidly, there are still a large number of cancer patients whose prognosis is not optimistic. At present, the treatment and prognosis of tumors are mainly based on the clinical staging of tumors, that is, the American Joint Committee on Cancer (AJCC) staging system. However, with the continuous deepening of the concept of precision medicine, the model of evaluating the prognosis of patients based only on tumor staging obviously has certain limitations. Clinically, it is urgent to construct an effective method for assessing the risk of prognosis of patients by applying indicators closely related to the prognosis...

Claims

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Application Information

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IPC IPC(8): G01N33/574
CPCG01N33/574G01N2800/52
Inventor 葛均波程蕾蕾王妍姜惠琴林瑾仪张晨璐陈佳慧章箎吴薇李静王春晖沈毅辉张卉
Owner ZHONGSHAN HOSPITAL FUDAN UNIV
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