A drug analyzer with adaptive function
By using a scraper in the drug analyzer to clean the powder on the rotating roller, and combining the design of the limit plate and sliding frame, we ensure that all the powder is added to the test tube, solving the problem of easy dissipation of the powder and achieving high accuracy of drug analysis Sex and comprehensiveness.
Patent Information
- Application Number
- CN202410495219.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2024-04-24
- Publication Date
- 2025-02-14
- Estimated Expiration
- 2044-04-24
AI Technical Summary
When existing drug analyzers detect and analyze tablets, they need to grind the tablets into powder first, causing the powder to easily dissipate, affecting the accuracy of the analysis results.
A drug analyzer with adaptive function was designed, using a scraper to clean the powder on the rotating roller, combined with the design of the limiting plate and sliding frame, ensuring that the powder is all added to the test tube, and the tablet is realized through the cutting assembly and sampling mechanism. quantitative sampling and multi-point measurement.
It effectively avoids the dissipation of the powder, ensures that the powder is completely dissolved into the test tube, improves the accuracy and comprehensiveness of drug analysis, reduces drug residues, and improves the accuracy of the analysis terminal.
Smart Images

Figure CN118329569B_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of analyzers, and in particular to a drug analyzer with an adaptive function. Background Art
[0002] A drug analyzer is an instrument for detecting and analyzing drug ingredients, which allows operators to compare the measured data with a network database to determine the effects and functions of the drug. Currently, when detecting and analyzing tablet drugs, the drug must first be ground into powder, then mixed with water, and then analyzed using spectrometers and other analytical instruments for the solvent component of the drug. During the drug grinding process, part of the powder will adhere to the grinding roller, and at the same time, affected by the operator's exhaled gas, the powder is easily dispersed in the air, reducing the overall amount of the powder, thereby causing the concentration of the drug solvent after mixing to become lower, affecting the results of the measured analysis. Summary of the invention
[0003] In order to overcome the problems described in the background art, the present invention provides a drug analyzer with an adaptive function.
[0004] The technical solution is: a drug analyzer with adaptive function, including a shell, a first fixed shell is fixedly connected to the side wall of the shell, a cover is detachably installed on the first fixed shell, a drug analysis terminal and a symmetrical first power member are fixedly connected in the first fixed shell, the first power member is located above the drug analysis terminal, the first power member is installed with a first fixed plate, a first sliding frame is slidably arranged on the first fixed plate, a spring is installed between the first sliding frame and the first fixed plate, a rotating roller is rotatably arranged at the lower end of the first sliding frame, the drug analysis terminal is installed with evenly distributed test tubes, the first fixed plate is fixedly connected to an evenly distributed limiting plate on the side away from the first power member, a straight line formed by the center point on the limiting plate and the center point on the adjacent test tube is projected on the upper surface of the drug analysis terminal parallel to the center line of the first power member, the limiting plate is provided with a V-shaped groove, the V-shaped groove of the limiting plate is used to gather tablet powder, the first sliding frame is fixedly connected with a scraper that contacts and cooperates with the rotating roller thereon, and the scraper is used to clean the rotating roller of the first sliding frame.
[0005] The cam is provided with a first sliding plate, the first sliding plate is limitedly slidably arranged in the shell, a spring is installed between the first sliding plate and the shell, a middle part of the first sliding plate is fixedly connected to the second fixed shell, the first sliding plate is embedded with a symmetrical second power member, and the symmetrical second power member is jointly installed with a second sliding frame, the second sliding frame is located at the outer side of the second fixed shell, the second fixed shell is slidably provided with a third sliding frame distributed equidistantly in the circumferential direction, the third sliding frame is provided with a convex column, the second sliding frame is provided with a sliding groove distributed equidistantly in the circumferential direction, the convex column of the third sliding frame is slidably matched with the adjacent sliding groove on the second sliding frame, the shell is detachably slidably provided with a filling shell and a storage shell, the filling shell is located above the third sliding frame, and the storage shell is located below the second fixed shell, and a cutting component for annularly cutting tablets is provided on the shell.
[0006] The third sliding frames which are evenly distributed in the circumferential direction cooperate to form a hemispherical groove, and the hemispherical groove formed by the third sliding frames which are evenly distributed in the circumferential direction is used to keep the flat tablet in a centered state.
[0007] The cutting assembly includes a third power member, which is embedded in the upper part of the shell, and the third power member is installed with a third fixed shell, and the third fixed shell is located in the shell, and the lower side of the third fixed shell is fixedly connected with a first fixed sleeve, the inner diameter of the first fixed sleeve is smaller than the inner diameter of the third fixed shell, and the lower end of the first fixed sleeve is an annular cutting knife for cutting tablets, and an elastic telescopic rod is fixedly connected in the third fixed shell, and the shell is fixedly connected with a support rod, and the support rod is located in the middle of the second fixed shell, and the support rod is located below the elastic telescopic rod.
[0008] A first cleaning brush is fixedly connected to the lower part of the third fixed shell, and the first cleaning brush is used for cleaning the cut surface of the tablet.
[0009] It also includes a sampling mechanism for multi-point sampling, the sampling mechanism is arranged on the shell, the sampling mechanism includes a second fixing sleeve, the second fixing sleeve is fixedly connected to the lower part of the third fixing shell through a connecting column, the side wall of the second fixing sleeve is fixedly connected with an arc-shaped first fixing frame, the first fixing frame is provided with two symmetrical first guide grooves and two symmetrical second guide grooves, a sampling shell is arranged in the first fixing frame, the second fixing sleeve is provided with evenly distributed through holes, the through holes of the second fixing sleeve are used for adjacent sampling shells to pass through, the sampling shell is fixedly connected with two symmetrical first limiting columns and two symmetrical second limiting columns, the first limiting columns and the second limiting columns are respectively located in adjacent first guide grooves and adjacent second guide grooves, the first fixing frame is fixedly connected with a fourth power member, The fourth power member is installed with a second fixed frame, the second fixed frame is provided with two symmetrical inclined grooves, a sliding block is slidably arranged between the two inclined grooves on the second fixed frame, the sliding block is slidably arranged with an n-shaped frame, the n-shaped frame is fixed with two symmetrical second fixed plates and two symmetrical third fixed plates, two adjacent third fixed plates are located between two adjacent second fixed plates, the second fixed plate and the third fixed plate are both provided with limiting grooves, the first limiting column and the adjacent second limiting column are jointly located in the limiting groove of the adjacent third fixed plate and slide, and the first limiting column is also located in the limiting groove of the adjacent second fixed plate and slides, the sampling shell is provided with a pushing assembly for cleaning its inner wall, and the evenly distributed first fixed frames are jointly provided with a conveying assembly for transporting samples.
[0010] The uniformly distributed sampling shells are evenly distributed in the vertical direction and the circumferential direction, and are used for layered sampling of the sampled tablets.
[0011] The pusher assembly includes a sliding push rod, which is slidably arranged in an adjacent sampling shell, a tension spring is installed between the sliding push rod and the adjacent sampling shell, and the sliding push rod and the adjacent sliding block are squeezed together, the first fixed frame is provided with two symmetrical third guide grooves, and the sliding push rod is located in the two adjacent third guide grooves and slides.
[0012] The conveying assembly includes uniformly distributed first guide rods, which are respectively fixed to the side walls of the adjacent first fixed frames, the first guide rods are slidably provided with a fifth power member, the fifth power member is fixedly connected to a storage shell, the storage shell is located at the lower side of the adjacent sampling shell, and the upper surface of the storage shell is flush with the lower surface of the adjacent sampling shell, the storage shell is slidably provided with a second sliding plate, a tension spring is installed between the second sliding plate and the adjacent storage shell, the first fixed shell is fixedly connected to a limiting frame, and the second sliding plate is provided with a convex column that is extruded and matched with the limiting frame.
[0013] The cleaning mechanism also includes a cleaning mechanism for cleaning the entire upper surface of the third sliding frame, the cleaning mechanism is arranged on the second fixed shell, the cleaning mechanism includes a fourth fixed plate distributed equidistantly in the circumferential direction, the fourth fixed plates distributed equidistantly in the circumferential direction are all fixedly connected to the upper surface of the second fixed shell, the fourth fixed plate is rotatably provided with a rotating frame, a torsion spring is installed between the rotating frame and the adjacent fourth fixed plate, a second cleaning brush is fixedly connected to one end of the rotating frame away from the fourth fixed plate, the second cleaning brush is located above the adjacent third sliding frame, the third sliding frame is fixedly connected to a second guide rod, and the second guide rod is used for limiting and squeezing the adjacent rotating frame.
[0014] The technical effect achieved by the present invention is as follows: the present invention utilizes a scraper to clean the rotating roller on the first sliding frame, so as to facilitate the addition of all the medicine powder into the test tube, and cooperates with the closed chamber of the first fixed shell to prevent the gas exhaled by the operator from blowing the medicine powder, thereby further ensuring that all the medicine powder is dissolved into the test tube, and improving the accuracy of the drug data measured by the device, and utilizing the cutting of the first fixed sleeve to facilitate the subsequent extraction of the quantitative medicine in the middle of the tablet, and to prevent the sugar coating attached to the outside of the tablet from affecting the drug analysis results, and then cooperates with multiple sampling shells to sample different parts of the drug center, so as to facilitate the device to measure and analyze different parts of the drug, thereby improving the comprehensiveness of the drug analysis of the device, and reducing the drug residue by cleaning the cleaning cloth, the first cleaning brush and the second cleaning brush on the storage shell, thereby further improving the accuracy of the drug analysis terminal for the drug. BRIEF DESCRIPTION OF THE DRAWINGS
[0015] Figure 1 It is a schematic diagram of the three-dimensional structure of the present invention;
[0016] Figure 2 It is a schematic diagram of the structure of the internal parts of the housing and the first fixed housing of the present invention;
[0017] Figure 3 It is a schematic structural diagram of the components of the first fixed plate and the first sliding frame of the present invention;
[0018] Figure 4 A cross-sectional view of the components of the first sliding frame and the scraper of the present invention;
[0019] Figure 5 It is a three-dimensional structural schematic diagram of the support mechanism of the present invention;
[0020] Figure 6 is a cross-sectional view of the support mechanism of the present invention;
[0021] Figure 7 It is a three-dimensional structural schematic diagram of the conveying assembly of the present invention;
[0022] Figure 8 is a cross-sectional view of a cutting assembly of the present invention;
[0023] Fig. 9 is a cross-sectional view of the sampling mechanism of the present invention;
[0024] Fig.10 An exploded view of the sampling mechanism of the present invention;
[0025] Fig.11 is a cross-sectional view of a conveying assembly of the present invention;
[0026] Fig.12 A first cross-sectional view of the cleaning mechanism of the present invention;
[0027] Fig.13 This is a second cross-sectional view of the cleaning mechanism of the present invention.
[0028] in:
[0029] 1-shell, 11-first fixed shell, 12-cover, 13-drug analysis terminal, 14-first power member, 15-first fixed plate, 16-first sliding frame, 161-test tube, 162-limiting plate, 17-scraper;
[0030] 2-first sliding plate, 21-second fixed shell, 24-second sliding frame, 23-second power member, 25-third sliding frame, 26-filling shell, 27-storage shell;
[0031] 3-third power member, 31-third fixing shell, 32-first fixing sleeve, 33-elastic telescopic rod, 34-support rod;
[0032] 35- first cleaning brush;
[0033] 4-second fixing sleeve, 41-first fixing frame, 411-first guide groove, 412-second guide groove, 42-sampling shell, 421-first limiting column, 422-second limiting column, 43-fourth power member, 44-second fixing frame, 45-sliding block, 46-n-shaped frame, 47-second fixing plate, 48-third fixing plate, 49-sliding push rod, 491-third guide groove;
[0034] 5-first guide rod, 51-fifth power member, 52-storage shell, 53-second sliding plate, 54-limiting frame;
[0035] 7-fourth fixed plate, 71-rotating frame, 72-second cleaning brush, 73-second guide rod. DETAILED DESCRIPTION
[0036] The technical solution of the present invention is further described below in conjunction with the accompanying drawings. The first power member, the second power member, the third power member and the fourth power member are all electric push rods, and the fifth power member is an electric slider.
[0037] Research has found that when using traditional analyzers to analyze tablets, it is often necessary to crush the tablets into powder, then mix the powder with water to prepare a drug solvent, and then analyze the tablets using spectroscopy and other methods. However, during the above-mentioned crushing process, a large amount of powder adheres to the material roller. At the same time, affected by the indoor environment, a large amount of powder is easily lost, affecting the accuracy of subsequent measurement and analysis results of the tablets.
[0038] In view of this, the present invention designs a drug analyzer which can isolate external influences and improve the measurement and analysis results of tablets.
[0039] Example 1: A drug analyzer with adaptive function, referring to Figure 1-Figure 4 As shown, it includes a shell 1, a first fixed shell 11 is fixedly connected to the left side of the shell 1, a control panel is installed on the shell 1, a cover 12 is detachably installed on the left side of the first fixed shell 11, a drug analysis terminal 13 electrically connected to the control panel is fixedly connected to the lower side of the first fixed shell 11, and the drug analysis terminal 13 is composed of sensors such as spectral sensors, electrochemical sensors, biosensors, optical sensors, and gas sensors. Two first power members 14 electrically connected to the control panel are fixedly connected to the left side of the first fixed shell 11. The two first power members 14 are symmetrically distributed front and back. The first power members 14 are located above the drug analysis terminal 13, and the telescopic ends of the two first power members 14 are jointly installed with a first fixed plate 15, and a first sliding frame 16 is slidably provided on the right part of the first fixed plate 15. Two springs symmetrically installed front and back are installed between the first sliding frame 16 and the first fixed plate 15, and a rotating roller for squeezing tablets is rotatably provided at the lower end of the first sliding frame 16, and the elastic force of the spring between the first sliding frame 16 and the first fixed plate 15 is used to facilitate uniform tablet squeezing. The extrusion force is increased to facilitate the tablet to form a powder with uniform particles, which is convenient for the powder to be quickly dissolved in water. The left part of the drug analysis terminal 13 is provided with three evenly distributed round holes, and the three round holes of the drug analysis terminal 13 are all installed with test tubes 161. The round holes of the drug analysis terminal 13 are provided with a vibration block, which is used to make the test tube 161 shake slightly to accelerate the dissolution of the powder in water. The drug analysis terminal 13 uses spectroscopy to measure and analyze the drug solvent. The right side of the first fixed plate 15 is fixed with three evenly distributed limit The projection of the straight line formed by the center point of the limiting plate 162 and the center point of the adjacent test tube 161 on the upper surface of the drug analysis terminal 13 is parallel to the center line of the first power member 14. The limiting plate 162 is provided with a V-shaped groove for gathering tablet powder. The first sliding frame 16 is fixedly connected with a scraper 17 for cleaning the rotating roller thereon. The scraper 17 is used to scrape the drug powder so that all the drug powder is dissolved in the water of the test tube 161, thereby ensuring the concentration of the drug solvent in the test tube 161, thereby improving the accuracy of drug analysis by the drug analysis terminal 13.
[0040] When analyzing the drugs, the operator opens the cover 12, then takes three test tubes 161 and adds an appropriate amount of water therein, and then places the three test tubes 161 in turn into the three round holes on the left side of the drug analysis terminal 13, and then the operator places the tablets to be tested on the upper surface of the drug analysis terminal 13, and then the operator closes the cover 12 to complete the preliminary preparations.
[0041] After the preliminary preparations are completed, the operator starts the two first power members 14 through the control panel on the shell 1. The first power member 14 drives the first sliding frame 16 and other connected connections to move to the left together through the first fixed plate 15. The first sliding frame 16 moves to the left to rotate the rotating roller on it to squeeze the tablets placed on the drug analysis terminal 13. During this process, the scraper 17 simultaneously scrapes the rotating roller on the first sliding frame 16, so that the tablet powder is located on the upper surface of the drug analysis terminal 13. Then the first fixed plate 15 continues to drive the three limiting plates 162 to move to the left. The limiting plates 162 move to the left to scrape and gather the squeezed powder on the drug analysis terminal 13, and drive all the powder to the upper end of the test tube 161, so that the quantitative powder is all added to the inner test tube 161, that is, a drug solution of a specified concentration is formed in the test tube 161, thereby improving the accuracy of the subsequent tablet measurement of the device.
[0042] After the tablet solution is prepared, the control panel on the shell 1 controls the two first power members 14 to drive the first fixed plate 15 and the first sliding frame 16 to move to the right and reset, and then the drug analysis terminal 13 works to perform data analysis on the powder solution in the test tube 161. The spectral sensor in the drug analysis terminal 13 is controlled by a single-chip microcomputer, which is equipped with detectors such as a thermal conductivity detector, a hydrogen flame ionization detector, an electron capture detector, an ammonia phosphorus detector, a flame photometry detector and a mass spectrometer detector, and the drug analysis terminal 13 can perform constant temperature or programmed temperature operation on the drug solution. The subsequent spectral sensor measures and analyzes the powder solution. At the same time, the gas sensor in the drug analysis terminal 13 works to analyze the gas in the monitored drug storage environment, thereby improving the accuracy of the device for drug analysis. The analyzed data is then displayed on the control panel on the shell 1 to complete the drug analysis.
[0043] Example 2: Based on Example 1, refer to Figure 5 and Figure 6As shown, it also includes a supporting mechanism, which is arranged in the shell 1, and the supporting mechanism is used to keep the tablet centered. The supporting mechanism includes a first sliding plate 2, and the first sliding plate 2 is limitedly slidably arranged in the lower part of the shell 1. The lower surface of the first sliding plate 2 is fixedly connected to four springs fixed to the shell 1, and the middle part of the first sliding plate 2 is fixedly connected to the second fixed shell 21. The upper part, middle part and lower part of the second fixed shell 21 are respectively regular octagonal, truncated cone and cylindrical. The first sliding plate 2 is embedded with two second power members 23 electrically connected to the control panel, and the two second power members 23 are symmetrically distributed. The telescopic ends of the two second power members 23 are jointly installed with a second sliding frame 24 located on the outer side of the second fixed shell 21, and the upper part of the second fixed shell 21 is slidably provided with four third sliding frames 2 distributed equidistantly in the circumferential direction. 5. The four third sliding racks 25 cooperate to form a hemispherical groove. The hemispherical groove formed by all the third sliding racks 25 is used for the flat tablet to be in a centered state. Two symmetrical protrusions are arranged on the opposite sides of the four third sliding racks 25. The second sliding rack 24 is provided with four groups of slide grooves equidistantly distributed in the circumferential direction, and each group of slide grooves includes two. The two protrusions of the third sliding rack 25 slide in the adjacent slide grooves on the second sliding rack 24 respectively. The right part and the lower part of the shell 1 are respectively detachably slidably provided with a filling shell 26 and a storage shell 27. The filling shell 26 is provided with a switch door. The left end of the filling shell 26 is located above the four third sliding racks 25, and the storage shell 27 is located directly below the second fixed shell 21. A cutting assembly is arranged on the shell 1. The cutting assembly is used to cut the tablets, so as to facilitate sampling of the middle part of the tablets.
[0044] Reference Figure 3 , Figure 7 and Figure 8 As shown, the cutting assembly includes a third power member 3 electrically connected to the control panel, the fixed portion of the third power member 3 is embedded in the upper part of the shell 1, the telescopic end of the third power member 3 is installed with a third fixed shell 31 located in the shell 1, and the lower side of the third fixed shell 31 is fixedly connected with a first fixed sleeve 32, the lower end of the first fixed sleeve 32 is an annular cutting knife for cutting tablets, and the inner diameter of the first fixed sleeve 32 is smaller than the inner diameter of the third fixed shell 31, and the inner diameter of the first fixed sleeve 32 is smaller than the maximum diameter of the tablet, and an elastic telescopic rod 33 is fixedly connected in the third fixed shell 31, and a support rod 34 is fixedly connected to the shell 1, the support rod 34 is located in the middle of the second fixed shell 21, and the support rod 34 is located below the elastic telescopic rod 33, and the lower part of the third fixed shell 31 is fixedly connected with a first cleaning brush 35 for cleaning the cut surface of the tablet, and the tablet is divided by the cutting knife on the first fixed sleeve 32, and then the first cleaning brush 35 is used for cleaning to prevent the sugar-coated fragments of the tablet from affecting the accuracy of the drug analysis of the device.
[0045] Reference Figure 7 , Fig. 9 and Fig.10As shown, a sampling mechanism is also included, which is arranged on the shell 1 and is used for multi-point sampling of the tablets. The sampling mechanism includes a second fixing sleeve 4, which is fixed to the lower part of the third fixing shell 31 through a connecting column, and the second fixing sleeve 4 is located above the first cleaning brush 35. The front side, left side and rear side of the second fixing sleeve 4 are all fixedly connected to the first fixing frame 41, and the three first fixing frames 41 are all provided with two first guide grooves 411 symmetrically arranged in front and back and two second guide grooves 412 symmetrically arranged in front and back, and the first guide groove 411 is located above the second guide groove 412, and a sampling shell 42 is arranged in the first fixing frame 41, and the three sampling shells 42 The second fixing sleeve 4 is evenly distributed in the vertical direction and the circumferential direction, and is used for layered sampling of the sampled tablets. The second fixing sleeve 4 is provided with three evenly distributed through holes, and the through holes of the second fixing sleeve 4 are used for the adjacent sampling shell 42 to pass through. The upper part of the sampling shell 42 is fixedly connected with two symmetrical first limiting posts 421 and two symmetrical second limiting posts 422. The length of the second limiting posts 422 is greater than the length of the first limiting posts 421. The first limiting posts 421 and the second limiting posts 422 are respectively located in the adjacent first guide groove 411 and the adjacent second guide groove 412. The upper part of the first fixing frame 41 is fixedly connected with a fourth power member 43 electrically connected to the control panel. The telescopic end of the fourth power member 43 is installed with a second fixed frame 44, and the second fixed frame 44 is provided with two inclined grooves symmetrical in front and back. A sliding block 45 is slidably provided between the two inclined grooves on the second fixed frame 44, and the sliding block 45 is provided with an n-shaped frame 46 in a limited sliding manner. The lower end of the n-shaped frame 46 is fixedly connected with two second fixed plates 47 symmetrical in front and back and two third fixed plates 48 symmetrical in front and back. The two adjacent third fixed plates 48 are located between the two adjacent second fixed plates 47, and the sampling shell 42 is located between the two adjacent third fixed plates 48. The second fixed plate 47 and the third fixed plate 48 are both provided with limited grooves, and the upper limit groove of the third fixed plate 48 is approximately Y-shaped, the limiting groove of the second fixed plate 47 is folded, and the folded limiting groove of the second fixed plate 47 is partially connected with the upper limiting groove of the third fixed plate 48, the first limiting column 421 and the adjacent second limiting column 422 are jointly located in the limiting groove of the adjacent third fixed plate 48 and slide, and the first limiting column 421 is also located in the limiting groove of the adjacent second fixed plate 47 and slides, and the sampling shell 42 is provided with a pushing assembly for cleaning its inner wall, and the evenly distributed first fixed frame 41 is jointly provided with a conveying assembly for transporting samples, and three sampling shells 42 are used to sample different parts of the tablet, so as to facilitate the subsequent comprehensive detection and analysis of the tablet by the device.
[0046] Reference Figure 9-11As shown, the push assembly includes a sliding push rod 49, which is slidably arranged in an adjacent sampling shell 42, a tension spring is installed between the sliding push rod 49 and the adjacent sampling shell 42, and the sliding push rod 49 and the adjacent sliding block 45 are squeezed together, a limiting ring for limiting the adjacent sliding push rod 49 is arranged in the sampling shell 42, and the first fixed frame 41 is provided with two third guide grooves 491 symmetrical in front and back, and the third guide groove 491 is composed of a horizontal section, an arc section and a vertical section. The sliding push rod 49 is located in the two adjacent third guide grooves 491 and slides. The reciprocating movement of the sliding push rod 49 facilitates the discharge of the quantitative sample taken out of the sampling shell 42, and at the same time, the residual powder in the sampling shell 42 is scraped off, thereby improving the accuracy of subsequent drug measurement and analysis.
[0047] Reference Figure 7 , Fig. 9 and Fig.11 As shown, the conveying assembly includes three first guide rods 5, which are respectively fixed to the side walls of adjacent first fixed frames 41, and the first guide rods 5 are slidably provided with a fifth power member 51 electrically connected to the control panel, and the lower surface of the fifth power member 51 is fixedly connected to a storage shell 52 located at the lower side of the adjacent sampling shell 42, and the upper surface of the storage shell 52 is flush with the lower surface of the adjacent sampling shell 42, and the storage shell 52 is provided with a cleaning cloth for cleaning the adjacent sampling shell 42, and the lower part of the storage shell 52 is slidably provided with a second sliding plate 53, and the side wall of the second sliding plate 53 is fixedly connected to a tension spring fixed to the adjacent storage shell 52, and the upper surface of the first fixed shell 11 is fixedly connected to a limiting frame 54, and the second sliding plate 53 is provided with a convex column, and the limiting frame 54 is used to limit and squeeze the convex columns of the three second sliding plates 53, and the three storage shells 52 are used to transport the quantitatively sampled drugs to the drug analysis terminal 13 respectively, so as to facilitate the subsequent analysis of different samples of tablets and further improve the accuracy of drug analysis by the device.
[0048] like Fig.12 and Fig.13 As shown, it also includes a cleaning mechanism, which is arranged on the second fixed shell 21, and is used to clean the upper surface of the entire third sliding frame 25. The cleaning mechanism includes four fourth fixed plates 7, and the four fourth fixed plates 7 are all fixedly connected to the upper surface of the second fixed shell 21. A rotating frame 71 is rotatably arranged on the upper part of the fourth fixed plate 7, and two symmetrical torsion springs are installed between the rotating frame 71 and the adjacent fourth fixed plate 7. In the initial state, the torsion spring is in a force storage state, and the opposite ends of the four rotating frames 71 are fixedly connected with a second cleaning brush 72 for cleaning the adjacent third sliding frame 25, and a second guide rod 73 is fixedly connected to the upper side surface of the third sliding frame 25. The second guide rod 73 is used to limit and squeeze the adjacent rotating frame 71, and the second cleaning brush 72 is used to clean the adjacent third sliding frame 25, so as to further reduce the residue of the drug, thereby further improving the accuracy of the drug analysis of the device.
[0049] In the prior art, when performing drug analysis on tablets with sugar coating, it is difficult for operators to completely remove the sugar coating because the tablets are flat, small and the sugar coating is too thin. In addition, too much drug is easily scraped off during the removal process, which affects the concentration of the drug solvent subsequently formed, thereby affecting the results of the analyzer's measurement and analysis of the drug solution. In view of this, the present invention designs a drug analyzer that performs quantitative sampling and measurement on tablets with sugar coating, and the samples taken do not contain sugar coating.
[0050] When analyzing the tablets with sugar coating, the specific implementation method is as follows: the operator opens the switch door on the filling shell 26 and places the tablets with sugar coating thereon, so that the tablets slide through the filling shell 26 into the hemispherical groove formed by the four third sliding racks 25, and at this time the center of the flat tablet is located on the center line of the first fixed sleeve 32, and then the operator starts the third power member 3 through the control panel on the shell 1, and the third power member 3 drives the third fixed shell 31 and the first fixed sleeve 32 to move downward, and the first fixed sleeve 32 moves downward so that the annular cutting knife on it contacts and squeezes the tablets placed on the four third sliding racks 25, and then the third power member 3 continues to work, and the first fixed sleeve 32 performs annular cutting on the middle part of the tablet, and the cut tablet is located in the first fixed sleeve 32. In this process, the lower side of the cut tablet contacts the upper end of the support rod 34, and the lower end of the elastic telescopic rod 33 contacts the upper side of the cut tablet, and then the first fixed sleeve 32 continues to move to complete the cutting of the tablet, and at the same time, the first fixed sleeve 32 contacts and squeezes the four third sliding racks 25.
[0051] After completing the cutting of the tablets, the third power member 3 continues to work. At this time, the height of the cut tablets remains unchanged under the limiting action of the elastic telescopic rod 33 and the support rod 34. The third power member 3 continues to drive the third fixed shell 31 and the first fixed sleeve 32 and other connected parts to move downward together, so that the cut tablets are located in the third fixed shell 31. During this process, the elastic telescopic rod 33 is compressed and elastically contracts, and the first fixed sleeve 32 moves through the four third sliding frames 25 to drive the second fixed shell 21 and the first sliding plate 2 and other connected parts to move downward. The first sliding plate 2 moves downward to compress the connected spring, and at the same time the first cleaning brush 35 cleans the cut surface of the tablet entering the third fixed shell 31 to prevent sugar-coated fragments from adhering to the cut surface of the cut tablet.
[0052] After the third power member 3 has finished working, the cut tablets are located in the middle of the overlap of the third fixed shell 31 and the second fixed sleeve 4. Then the control panel on the shell 1 starts the three fourth power members 43. The fourth power member 43 drives the adjacent second fixed frame 44 to move toward the direction close to the third fixed shell 31. At this time, due to the limiting effect of the adjacent third guide groove 491, the sliding push rod 49 cannot swing. At this time, under the tension of the tension spring connected to the sliding push rod 49, the sliding push rod 49 squeezes the adjacent sliding block 45 to move upward until the upper end of the sliding push rod 49 is located at the uppermost side of the adjacent third guide groove 491. At this time, the sliding block 45 is located at the uppermost side of the inclined groove on the adjacent second fixed frame 44, and the sliding push rod 49 contacts the limiting ring in the adjacent sampling shell 42.
[0053] When the sliding push rod 49 has finished moving in the adjacent sampling shell 42, the second fixed frame 44 continues to squeeze the adjacent sliding block 45 to move, and the sliding block 45 drives the n-shaped frame 46, the second fixed plate 47 and the third fixed plate 48 to move together. At this time, the sampling shell 42 will rotate around the adjacent first limiting column 421. During this process, the second limiting column 422 slides along the adjacent second guide groove 412, and the sliding push rod 49 slides along the adjacent third guide groove 491. At the same time, the movement of the second fixed plate 47 and the third fixed plate 48 causes the adjacent first limiting column 421 and the adjacent second limiting column 422 to be respectively located at one end of the upper limiting groove of the adjacent second fixed plate 47 and the adjacent third fixed plate 48 away from the adjacent n-shaped frame 46. At this time, the swing of the sampling shell 42 will be in a horizontal state.
[0054] After the sampling shell 42 swings to a horizontal state, the three fourth power members 43 continue to work, so that the sampling shell 42 enters the third fixed shell 31 through the adjacent through holes on the second fixed sleeve 4, and the subsequent sampling shell 42 will be inserted into the tablet clamped between the elastic telescopic rod 33 and the support rod 34. Since the three sampling shells 42 are equidistantly distributed in the vertical direction, the three sampling shells 42 will sample parts at different depths from the center of the tablet. After the three fourth power members 43 have finished working, the three sampling shells 42 will complete quantitative sampling of different parts, and the control panel on the subsequent shell 1 will start the reverse reset of the three fourth power members 43. At this time, the sampling shell 42 will perform the above-mentioned reverse work, and the sampling shell 42 will swing back to a vertical state. At this time, the sampling shell 42 is located above the adjacent storage shell 52, and at the same time, the sliding push rod 49 is reset to push the tablets taken from the adjacent sampling shell 42 into the adjacent storage shell 52.
[0055] After the fourth power member 43 finishes working, the control panel on the shell 1 starts the three fifth power members 51, and the fifth power member 51 moves to the left along the adjacent first guide rod 5, and the fifth power member 51 drives the adjacent storage shell 52 and the second sliding plate 53 to move to the left together, and the storage shell 52 moves so that the cleaning cloth on it wipes the lower surface of the adjacent sampling shell 42 and the lower surface of the adjacent sliding push rod 49, thereby reducing the drug residue and improving the accuracy of the downward measurement. When the fifth power member 51 moves to the left limit, the limit frame 54 limits and squeezes the convex columns of the three adjacent second sliding plates 53, so that the second sliding plate 53 moves to the right on the adjacent storage shell 52. At this time, the storage shell 52 is located above the drug analysis terminal 13. With the movement of the second sliding plate 53, the drug sample in the storage shell 52 will fall to the upper surface of the drug analysis terminal 13. After the sampling of the sample tablets is completed, the three fifth power members 51 drive the adjacent connection direction to move and reset.
[0056] After the sampled tablet is located on the upper surface of the drug analysis terminal 13, the operator starts the two first power members 14 through the control panel on the shell 1 to squeeze the drug and add the squeezed powder to the three test tubes 161 placed on the drug analysis terminal 13. After that, the drug analysis terminal 13 works to analyze the detailed data of the tablet at different positions from the center, so that the operator can have a comprehensive understanding of the tablet.
[0057] During the analysis of the tablets, the control panel starts the third power member 3 to work in reverse and reset, so that the third fixed shell 31 and the first fixed sleeve 32 move in reverse and reset. At this time, under the elastic force of the spring connected to the first sliding plate 2, the first sliding plate 2 drives the connected parts to reset together, and then the control panel starts the two second power members 23 to perform a single reciprocating operation. The second power member 23 first drives the second sliding frame 24 to move upward, and the second sliding frame 24 moves upward so that its upper slide groove squeezes the convex column of the adjacent third sliding frame 25, and the four third sliding frames 25 move away from each other, so that the tablet fragments on the four fall into the storage shell 27 through the second fixed shell 21, and the subsequent two second power members 23 work and reset, so that the four third sliding frames 25 return to their initial state, which is convenient for subsequent tablet sampling and analysis.
[0058] When the second cleaning brush 72 is in the closed position, the cleaning brush 73 is in the closed position, and the cleaning brush 73 is in the closed position, so that ... and the cleaning brush 73 is in the closed position, and the cleaning brush 73 is in the closed position, and the cleaning brush 73 is in the closed position, and the cleaning brush 73 is in the closed position, and the cleaning brush 73 is in the closed position, and the cleaning brush 73 is in the closed position, and the cleaning brush 73 is in the closed position, and the cleaning
[0059] It should be understood that the above description is only for exemplary purposes and is not meant to limit the present invention. Those skilled in the art will appreciate that variations of the present invention will be included within the scope of the claims herein.
Claims
1. A drug analyzer with an adaptive function, comprising a housing (1), a first fixed housing (11) being fixedly connected to a side wall of the housing (1), a cover (12) being detachably mounted on the first fixed housing (11), and a drug analysis terminal (13) being fixedly connected inside the first fixed housing (11), wherein: The device further comprises a first power member (14), the first power member (14) being fixedly connected to the first fixed shell (11), the first power member (14) being located above the drug analysis terminal (13), the first power member (14) being mounted with a first fixed plate (15), the first fixed plate (15) being slidably provided with a first sliding frame (16), a spring being mounted between the first sliding frame (16) and the first fixed plate (15), a rotating roller being rotatably provided at the lower end of the first sliding frame (16), the drug analysis terminal (13) being mounted with evenly distributed test tubes (161), the first fixed plate (15) being provided with a first sliding frame (16) and a first rotating roller being provided at the lower end of the first sliding frame (16). 15) A uniformly distributed limiting plate (162) is fixedly connected to a side away from the first power member (14); a projection of a straight line formed by a center point on the limiting plate (162) and a center point on an adjacent test tube (161) on the upper surface of the drug analysis terminal (13) is parallel to the center line of the first power member (14); the limiting plate (162) is provided with a V-shaped groove; the V-shaped groove of the limiting plate (162) is used to gather tablet powder; the first sliding frame (16) is fixedly connected to a scraper (17) in contact with a rotating roller thereon; the scraper (17) is used to clean the rotating roller of the first sliding frame (16); The invention also comprises a support mechanism for keeping the tablet centered, the support mechanism being arranged in the shell (1), the support mechanism comprising a first sliding plate (2), the first sliding plate (2) being arranged in the shell (1) in a limited sliding manner, a spring being installed between the first sliding plate (2) and the shell (1), a second fixed shell (21) being fixedly connected to the middle of the first sliding plate (2), a symmetrical second power member (23) being embedded in the first sliding plate (2), the symmetrical second power members (23) being jointly installed with a second sliding frame (24), the second sliding frame (24) being located on the outside of the second fixed shell (21), the The second fixed shell (21) is slidably provided with a third sliding frame (25) equidistantly distributed in the circumferential direction, the third sliding frame (25) is provided with a convex column, the second sliding frame (24) is provided with a sliding groove equidistantly distributed in the circumferential direction, the convex column of the third sliding frame (25) is slidably matched with the adjacent sliding groove on the second sliding frame (24), the shell (1) is detachably slidably provided with a filling shell (26) and a material storage shell (27), the filling shell (26) is located above the third sliding frame (25), the material storage shell (27) is located below the second fixed shell (21), and the shell (1) is provided with a cutting assembly for annularly cutting tablets; The third sliding frames (25) distributed equidistantly in the circumferential direction cooperate to form a hemispherical groove, and the hemispherical groove formed by the third sliding frames (25) distributed equidistantly in the circumferential direction is used to keep the flat tablet in a centered state; The cutting assembly comprises a third power member (3), the third power member (3) is embedded in the upper part of the shell (1), the third power member (3) is installed with a third fixed shell (31), the third fixed shell (31) is located in the shell (1), a first fixed sleeve (32) is fixedly connected to the lower side of the third fixed shell (31), the inner diameter of the first fixed sleeve (32) is smaller than the inner diameter of the third fixed shell (31), the lower end of the first fixed sleeve (32) is an annular cutting knife for cutting tablets, an elastic telescopic rod (33) is fixedly connected to the inside of the third fixed shell (31), and a support rod (34) is fixedly connected to the shell (1), the support rod (34) is located in the middle of the second fixed shell (21), and the support rod (34) is located below the elastic telescopic rod (33); A first cleaning brush (35) is fixedly connected to the lower portion of the third fixed shell (31), and the first cleaning brush (35) is used to clean the cut surface of the tablet.
2. A drug analyzer with adaptive function according to claim 1, characterized in that: The invention also comprises a sampling mechanism for multi-point sampling, the sampling mechanism being arranged on the housing (1), the sampling mechanism comprising a second fixing sleeve (4), the second fixing sleeve (4) being fixedly connected to the lower part of the third fixing shell (31) via a connecting column, the side wall of the second fixing sleeve (4) being fixedly connected to a first fixing frame (41) distributed in an arc shape, the first fixing frame (41) being provided with two symmetrical first guide grooves (411) and two symmetrical second guide grooves (412), the first fixing frame (41) being provided with a sampling shell ( 42), the second fixing sleeve (4) is provided with evenly distributed through holes, the through holes of the second fixing sleeve (4) are used for the adjacent sampling shell (42) to pass through, the sampling shell (42) is fixedly connected with two symmetrical first limiting pillars (421) and two symmetrical second limiting pillars (422), the first limiting pillars (421) and the second limiting pillars (422) are respectively located in the adjacent first guide groove (411) and the adjacent second guide groove (412), the first fixing frame (41) is fixedly connected with a fourth power member ( 43), the fourth power member (43) is installed with a second fixed frame (44), the second fixed frame (44) is provided with two symmetrical inclined grooves, a sliding block (45) is slidably provided between the two inclined grooves on the second fixed frame (44), the sliding block (45) is slidably provided with an n-shaped frame (46), the n-shaped frame (46) is fixedly connected with two symmetrical second fixed plates (47) and two symmetrical third fixed plates (48), and two adjacent third fixed plates (48) are located between two adjacent second fixed plates (47). The second fixing plate (47) and the third fixing plate (48) are both provided with limiting grooves, the first limiting column (421) and the adjacent second limiting column (422) are located in the limiting groove of the adjacent third fixing plate (48) and slide, and the first limiting column (421) is also located in the limiting groove of the adjacent second fixing plate (47) and slides, the sampling shell (42) is provided with a pushing assembly for cleaning the inner wall thereof, and the evenly distributed first fixing frames (41) are jointly provided with a conveying assembly for transporting samples.
3. A drug analyzer with adaptive function according to claim 2, characterized in that: The uniformly distributed sampling shells (42) are evenly distributed in the vertical direction and the circumferential direction, and are used for performing layered sampling on the sampled tablets.
4. A drug analyzer with adaptive function according to claim 2, characterized in that: The pusher assembly comprises a sliding push rod (49), the sliding push rod (49) is slidably arranged in the adjacent sampling shell (42), a tension spring is installed between the sliding push rod (49) and the adjacent sampling shell (42), and the sliding push rod (49) and the adjacent sliding block (45) are pressed and matched, and the first fixed frame (41) is provided with two symmetrical third guide grooves (491), and the sliding push rod (49) is located in the two adjacent third guide grooves (491) and slides.
5. A drug analyzer with adaptive function according to claim 4, characterized in that: The conveying assembly comprises uniformly distributed first guide rods (5), the uniformly distributed first guide rods (5) are respectively fixed to the side walls of the adjacent first fixed frames (41), the first guide rods (5) are slidably provided with a fifth power member (51), the fifth power member (51) is fixedly connected to a storage shell (52), the storage shell (52) is located at the lower side of the adjacent sampling shell (42), and the upper surface of the storage shell (52) is flush with the lower surface of the adjacent sampling shell (42), the storage shell (52) is slidably provided with a second sliding plate (53), a tension spring is installed between the second sliding plate (53) and the adjacent storage shell (52), the first fixed shell (11) is fixedly connected to a limiting frame (54), and the second sliding plate (53) is provided with a convex column that is pressed and matched with the limiting frame (54).
6. A drug analyzer with adaptive function according to claim 1, characterized in that: The cleaning mechanism further comprises a cleaning mechanism for cleaning the upper surface of the entire third sliding frame (25), the cleaning mechanism being arranged on the second fixed shell (21), the cleaning mechanism comprising fourth fixed plates (7) equidistantly distributed in the circumferential direction, the fourth fixed plates (7) equidistantly distributed in the circumferential direction being fixedly connected to the upper surface of the second fixed shell (21), the fourth fixed plates (7) being rotatably provided with a rotating frame (71), a torsion spring being installed between the rotating frame (71) and the adjacent fourth fixed plates (7), a second cleaning brush (72) being fixedly connected to one end of the rotating frame (71) away from the fourth fixed plate (7), the second cleaning brush (72) being located above the adjacent third sliding frame (25), the third sliding frame (25) being fixedly connected to a second guide rod (73), the second guide rod (73) being used for limiting and squeezing the adjacent rotating frame (71).
Citation Information
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