Methods and apparatus for treating rhinitis

a technology for rhinitis and rhinitis, applied in the direction of respirators, drug compositions, breathing protection, etc., can solve the problems of congestion and irritation in the nose, nose, eyes, throat and ears, congestion and irritation,

Inactive Publication Date: 2007-02-22
CAPNIA INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0011] The present invention provides methods and apparatus for treating patients, particularly patients suffering or at risk of suffering from rhinitis, by administering a treatment agent to the patient and simultaneously delivering a capnic gas to a nasal, oral, auricular, or ocular membrane of the patient. By “simultaneously,” it is meant that the treatment agent will be administered and the capnic gas delivered at the same time or within a very short time of each other, typically within 60 minutes, preferably within 30 minutes, and more preferably within

Problems solved by technology

Symptoms include a runny nose, sneezing, congestion and irritation in the nose, eyes, throat and ears.
The inf

Method used

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  • Methods and apparatus for treating rhinitis
  • Methods and apparatus for treating rhinitis
  • Methods and apparatus for treating rhinitis

Examples

Experimental program
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Embodiment Construction

[0022] An exemplary carbon dioxide dispenser 100 comprising a carbon dioxide cartridge 101 is illustrated in FIG. 1. The embodiment of FIG. 1 is described in greater detail in parent application Ser. No. 09 / 708,186, now U.S. Pat. No. 6,959,708, the full disclosure of which has previously been incorporated herein by reference. A user delivers a dose of carbon dioxide or other treatment gas, referred to generally as “capnic gases” (optionally carrying the systemic treatment agent to be delivered) by applying the top of the dispenser 608 to the user's nose or mouth and pushing a button 600 which releases an internal mechanism to allow the CO2 to flow from the top of the dispenser 608. The internal mechanism will lower the pressure of CO2 in the cartridge and will control the flow rate within suitable ranges, typically from 0.5 to 30 cc / sec. The flow rate may be maintained for a suitable time period, typically at least 2 seconds when suffusing the nasal and sinus passages. The device is...

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Abstract

Apparatus and methods deliver treatment agents simultaneously with capnic gases. The capnic gases can enhance the effectiveness of the treatment agent for treating rhinitis, lower the dosage of drug or concentration of agent necessary to achieve a therapeutic result, or both. Exemplary capnic gases include carbon dioxide, nitric oxide, nitrous oxide, and dilute acid gases.

Description

CROSS-REFERENCES TO RELATED APPLICATIONS [0001] This application is a continuation-in-part of U.S. application Ser. No. 11 / 192,852 (Attorney Docket No. 020017-000320US), filed Jul. 29, 2005, which was a continuation-in-part of U.S. application Ser. No. 09 / 708,186 (Attorney Docket No. 020017-000310US), filed Nov. 7, 2000 (now U.S. Pat. No. 6,959,708), which claimed the benefit of U.S. Provisional Patent Application Nos. 60 / 185,495, filed on Feb. 28, 2000 60 / 164,125, filed on Nov. 8, 1999, each of which is incorporated by reference herein.BACKGROUND OF THE INVENTION [0002] 1. Field of the Invention [0003] The present invention relates to drug delivery. More particularly, the present invention relates to methods and apparatus for delivering agents to mucosal and other tissue surfaces, in the presence of capnic gases, particularly for the treatment of rhinitis. [0004] Drug delivery to mucosal surfaces, such as the mucosa of the nose, is well known. While in some cases drugs delivered to...

Claims

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Application Information

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IPC IPC(8): A62B7/00
CPCA61H33/14A61H2033/145A61K33/00A61K45/06A61M15/0065A61M15/0041A61M37/00A61M2202/0225A61M2202/064A61M15/009A61M2202/0007A61M15/0083A61P11/00
InventorRASOR, JULIA S.RASOR, NED S.PEREIRA, GERARD F.
OwnerCAPNIA INC