Traditional Chinese medicine composition for treating subacute thyroiditis and preparation method thereof

Abstract

The invention discloses a traditional Chinese medicine composition for treating subacute thyroiditis. The composition is a preparation prepared from the following raw materials by weight: 15-30 parts of hedyotis diffusa, 9-15 parts of honeysuckle, 15-30 parts of dandelion, 15-30 parts of Chinese violet, 9-15 parts of root of common peony, 9-15 parts of radix scrophulariae, 9-15 parts of peach kernel, 9-15 parts of baked turtle shell and 15-30 parts of sweet wormwood. According to clinical study on the treatment of subacute thyroiditis, the traditional Chinese medicine composition provided by the invention has total effective rate of 93.34%, which is significantly better than 73.33% of a prednisone group, and can effectively reduce erythrocyte sedimentation rate and CRP of subacute thyroiditis patients, and effectively improve clinical symptoms of the patients; although the cooling time, improvement time of neck pain and regression time of neck tenderness are longer than those of the prednisone group, the goiter or nodule disappearance time shows no obvious difference from those of the prednisone group; relapse rate after drug withdrawal is 3.33%, which is significantly lower than 20% of the prednisone group; and the composition has little adverse reaction, which is significantly lower than that of the prednisone group. The invention also discloses a preparation method of the traditional Chinese medicine composition granules.

Description

technical field

[0001] The invention relates to a traditional Chinese medicine composition for treating subacute thyroiditis (subacute thyroiditis, SAT, also known as viral thyroiditis, DeQuervain's thyroiditis); the invention also relates to a preparation method of the traditional Chinese medicine composition. Background technique

[0002] In recent years, the incidence of subacute thyroiditis has been increasing year by year. The etiology has not been fully elucidated, and it is generally believed to be related to viral infection. It can be seen clinically that patients often have a history of upper respiratory tract infection before the onset of the disease, and the onset often changes with the seasons and has a certain prevalence. In addition, there are virus antibodies in the patient's blood, and the titer of the antibody is consistent with the stage of the disease. Coxsackie virus antibodies are the most common, followed by adenovirus antibodies, influenza virus antib...

Examples

Embodiment 1

[0026] Weigh 1,500 grams of Hedyotis, 900 grams of Silver Flower, 1,500 grams of Dandelion, 1,500 grams of Viola, 900 grams of Radix Paeoniae Rubra, 900 grams of Scrophulariae Scrophulariae, 1,500 grams of peach kernel, 900 grams of broiled turtle shell, 1,500 grams of Artemisia annua, add 4 Double the amount of water, decoct for 1.5 hours, filter, concentrate to a clear paste with a relative density of about 1.35 (80°C), add appropriate amount of dextrin, granulate (14-16 mesh), vacuum dry (80°C), and pack.

Embodiment 2

[0028] Weigh 2000 grams of Hedyotis, 1200 grams of Yinhua, 2000 grams of dandelion, 2000 grams of Viola chinensis, 1200 grams of red peony, 1200 grams of Scrophulariaceae, 2000 grams of peach kernels, 1200 grams of broiled turtle shells, 2000 grams of Artemisia annua, add 4 Double the amount of water, reflux and extract twice, each time for 1.5 hours, filter, combine the filtrate, recover ethanol until it has no alcohol smell, concentrate to a clear paste with a relative density of about 1.35 (80°C), add an appropriate amount of dextrin, and granulate (14 -16 mesh), vacuum-dried (80°C), and packaged.

Embodiment 3

[0030]Weigh 3000 grams of Hedyotis, 1500 grams of Silver Flowers, 3000 grams of Dandelion, 3000 grams of Viola chinensis, 1500 grams of Radix Paeoniae Rubra, 1500 grams of Scrophulariae Scrophulariae, 3000 grams of peach kernels, 1500 grams of broiled turtle shells, 3000 grams of Artemisia annua, add 4 Double the amount of water, reflux and extract three times, each time for 1.5 hours, filter, combine the filtrate, recover ethanol until it has no alcohol smell, concentrate to a clear paste with a relative density of about 1.35 (80°C), add an appropriate amount of dextrin, and granulate (14- 16 mesh), vacuum-dried (80°C), and packaged.

technical field

[0001] The invention relates to a traditional Chinese medicine composition for treating subacute thyroiditis (subacute thyroiditis, SAT, also known as viral thyroiditis, DeQuervain's thyroiditis); the invention also relates to a preparation method of the traditional Chinese medicine composition. Background technique

[0002] In recent years, the incidence of subacute thyroiditis has been increasing year by year. The etiology has not been fully elucidated, and it is generally believed to be related to viral infection. It can be seen clinically that patients often have a history of upper respiratory tract infection before the onset of the disease, and the onset often changes with the seasons and has a certain prevalence. In addition, there are virus antibodies in the patient's blood, and the titer of the antibody is consistent with the stage of the disease. Coxsackie virus antibodies are the most common, followed by adenovirus antibodies, influenza virus antib...

Examples

Embodiment 1

[0026] Weigh 1,500 grams of Hedyotis, 900 grams of Silver Flower, 1,500 grams of Dandelion, 1,500 grams of Viola, 900 grams of Radix Paeoniae Rubra, 900 grams of Scrophulariae Scrophulariae, 1,500 grams of peach kernel, 900 grams of broiled turtle shell, 1,500 grams of Artemisia annua, add 4 Double the amount of water, decoct for 1.5 hours, filter, concentrate to a clear paste with a relative density of about 1.35 (80°C), add appropriate amount of dextrin, granulate (14-16 mesh), vacuum dry (80°C), and pack.

Embodiment 2

[0028] Weigh 2000 grams of Hedyotis, 1200 grams of Yinhua, 2000 grams of dandelion, 2000 grams of Viola chinensis, 1200 grams of red peony, 1200 grams of Scrophulariaceae, 2000 grams of peach kernels, 1200 grams of broiled turtle shells, 2000 grams of Artemisia annua, add 4 Double the amount of water, reflux and extract twice, each time for 1.5 hours, filter, combine the filtrate, recover ethanol until it has no alcohol smell, concentrate to a clear paste with a relative density of about 1.35 (80°C), add an appropriate amount of dextrin, and granulate (14 -16 mesh), vacuum-dried (80°C), and packaged.

Embodiment 3

[0030]Weigh 3000 grams of Hedyotis, 1500 grams of Silver Flowers, 3000 grams of Dandelion, 3000 grams of Viola chinensis, 1500 grams of Radix Paeoniae Rubra, 1500 grams of Scrophulariae Scrophulariae, 3000 grams of peach kernels, 1500 grams of broiled turtle shells, 3000 grams of Artemisia annua, add 4 Double the amount of water, reflux and extract three times, each time for 1.5 hours, filter, combine the filtrate, recover ethanol until it has no alcohol smell, concentrate to a clear paste with a relative density of about 1.35 (80°C), add an appropriate amount of dextrin, and granulate (14- 16 mesh), vacuum-dried (80°C), and packaged.

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