A Chinese medicine composition for treating diabetes and its preparation method

Abstract

The invention discloses a Chinese medicine composition for treating diabetes and a preparation method thereof, and belongs to the technical field of Chinese medicine preparations. The Chinese medicine composition includes the following components by weight: 18-23 parts of cyperus rotundus, 17-20 parts of cyperus rotundus, 10-15 parts of white apricot, 10-16 parts of tortoise shell, 5-7 parts of northern bean root, 2-4 parts of hawthorn, and 1-2 parts of camellia pollen. The Chinese medicine composition disclosed in the invention includes cyperus rotundus, cyperus rotundus, white apricot, tortoise shell, northern bean root, hawthorn, and camellia pollen. Through reasonable compatibility, the medicament conforms to the compatibility treatment principle of "monarch, minister, assistant, and messenger", and cooperates to play the functions of replenishing qi and nourishing blood, nourishing yin and latent yang, quenching thirst, and clearing away heat and detoxification. Clinical results show that the Chinese medicine preparation of the present invention has a significant therapeutic effect on type 2 diabetes with deficiency of both qi and yin, and obtains an effect that is equal to or better than that of traditional Western medicine treatment, and provides a practical new drug for the efficient treatment of patients with type 2 diabetes with deficiency of both qi and yin.

Description

Technical Field

[0001] The present invention relates to the technical field of Chinese medicine preparations, and in particular to a Chinese medicine composition for treating diabetes and a preparation method thereof. Background Art

[0002] Diabetes mellitus (DM) is a metabolic disease caused by insufficient insulin secretion and / or defective action, which is mainly manifested as chronic hyperglycemia and can lead to a variety of serious complications. DM is mainly divided into type 1 diabetes (T1DM) and type 2 diabetes (T2DM). T2DM is a common type, and its number of patients accounts for more than 95% of the total number of DM patients. At present, the main Western medicines for the treatment of T2DM are ① insulin secretion promoters ② insulin sensitizers ② drugs that reduce carbohydrate absorption ④ aldose reductase inhibitors. However, from the perspective of the hypoglycemic drugs currently used or to be used in clinical practice, various Western medicines have certain limitations and adverse reactions, and even very serious toxic side effects.

[0003] From the earliest "spleen deficiency" and "diabetes", TCM has involved diabetes in modern medicine from the perspective of symptoms. TCM believes that its causes are complex, with abnormal endowment as the internal cause and diet, emotions and living habits as the external causes, which together lead to the occurrence of diabetes; the overall understanding of the pathogenesis is a mixture of deficiency and excess, with yin deficiency or qi deficiency as the root and phlegm and blood stasis as the symptoms; in the middle stage of diabetes, there is more deficiency of both qi and yin, which accounts for nearly half of patients with type 2 diabetes. Most studies also use this syndrome as the research object to study the therapeutic effects of various Chinese medicine prescriptions combined with Western medicine. It is found that auxiliary Chinese medicine treatment (Chinese medicine prescriptions, acupuncture, etc.) is ultimately more conducive to strengthening blood sugar control, improving insulin resistance, protecting and regulating pancreatic cell function, especially for the prevention and treatment of complications such as early diabetic nephropathy, diabetic peripheral neuropathy, and diabetic retinopathy. There are many new drugs for the treatment of T2DM in TCM, but there are many low-level duplications in Chinese patent medicine products, and there are many types of drug raw materials, and the formula is relatively complex, which produces certain side effects or the efficacy is not very obvious.

[0004] To this end, the present invention specially develops a traditional Chinese medicine composition with simple ingredients, safety and effectiveness for treating type 2 diabetes with deficiency of both qi and yin. Summary of the invention

[0005] The purpose of the present invention is to provide a Chinese medicine composition for treating diabetes and a preparation method thereof, so as to solve the problems existing in the above-mentioned prior art. The weight ratio of each component of the Chinese medicine preparation of the invention has good efficacy, and can completely replace traditional Western medicine for treating diabetes, and has a significant therapeutic effect on type 2 diabetes with deficiency of both qi and yin. The present invention provides a practical new drug for the efficient treatment of patients with type 2 diabetes with deficiency of both qi and yin.

[0006] To achieve the above object, the present invention provides the following solutions:

[0007] The present invention provides a Chinese medicine composition for treating diabetes, comprising the following components in parts by weight:

[0008] 18-23 parts of Chinese bunge, 17-20 parts of indigofera serrata, 10-15 parts of white apricot, 10-16 parts of tortoise shell, 5-7 parts of northern bean root, 2-4 parts of hawthorn and 1-2 parts of camellia pollen.

[0009] Further, it comprises the following components in parts by weight:

[0010] 23 parts of Radix Dipterocarpis, 20 parts of Indigofera serrata, 15 parts of Prunus armeniaca, 12 parts of Carapax testudinis, 5 parts of Rhizoma Atractylodis Macrocephalae, 4 parts of Fructus Crataegi and 2 parts of Camellia pollen.

[0011] The present invention also provides a method for preparing the Chinese medicine composition, comprising the following steps:

[0012] S1. Weigh a specified amount of components, add water and boil, and then filter and collect the first decoction filtrate;

[0013] S2. Add water to the filtered residue and boil it, collecting the second decoction filtrate;

[0014] S3. Combine the filtrates obtained from the two decoctions.

[0015] Furthermore, the amount of water added for decoction is 5-8 times the volume of the prescribed amount of components.

[0016] Furthermore, the decocting with water is performed by boiling and then simmering for 30-50 minutes.

[0017] The present invention also provides an application of the traditional Chinese medicine composition in preparing medicine for preventing and / or treating diabetes.

[0018] Furthermore, the drug also contains a pharmaceutically acceptable carrier.

[0019] Furthermore, the carrier includes one or more of an excipient, an emulsifier and a surfactant.

[0020] Furthermore, the dosage form of the drug includes tablets, capsules or decoctions.

[0021] The prescription of the Chinese medicine composition of the present invention is as follows:

[0022] The whole formula uses Chongyangmu and Saishanlan as the main medicines. Chongyangmu tastes pungent, bitter, and astringent, and is cool and slightly warm in nature. It enters the liver, lung, stomach, kidney, and intestinal meridians, and has the effects of replenishing qi and blood, removing blood stasis and activating blood circulation, replenishing the kidney, relieving asthma, lowering blood sugar, reducing swelling and eliminating toxins, dispelling wind and promoting qi, and relieving fever and inflammation; Saishanlan tastes slightly bitter and sweet, and is cool in nature. It enters the liver and gallbladder meridians, and can clear away heat and detoxify, disperse nodules, disperse blood stasis, cool blood, reduce swelling, and clear liver fire; the two are combined to replenish qi and blood, benefit the essence and nourish the kidney, soothe the liver and regulate qi, remove dampness and disinfect, clear the stomach, lung, and kidney fire, and can improve the syndrome of qi and yin deficiency.

[0023] White thorn apricot tastes sweet, light, cool in nature, and enters the lung, liver, kidney and heart meridians, and can stop bleeding, benefit the kidney, reduce inflammation, reduce swelling, relieve constipation, clear away heat and detoxify, etc.; tortoise shell tastes sweet, salty, cold, and enters the liver, kidney, and heart meridians, and has the effects of nourishing yin and suppressing yang, benefiting the kidney and strengthening bones, consolidating essence and stopping bleeding, nourishing blood and nourishing the heart, and can be used for yin deficiency and internal heat, yin deficiency and yang hyperactivity, and febrile yin deficiency and wind movement, etc. Both are ministerial drugs, nourishing yin and suppressing yang, strengthening the spleen and warming the kidney, anti-inflammatory, and removing dampness.

[0024] The root of northern bean is bitter and cold in nature. It belongs to the lung, stomach and large intestine meridians. It can clear away heat and detoxify, dispel wind and relieve pain. Hawthorn is sour, sweet and slightly warm. It belongs to the spleen, stomach and liver meridians. It can help digestion and invigorate the stomach, promote qi and disperse blood stasis, remove turbidity and reduce fat. It is used for meat stagnation, stomach distension, diarrhea and abdominal pain, blood stasis and amenorrhea, postpartum blood stasis, heart and abdomen stabbing pain, hernia pain, etc. The two are adjuvants. Camellia pollen has a special tea fragrance and tastes slightly sweet. It is rich in protein, amino acids, fatty acids, vitamins, active enzymes and other effective active ingredients. It has the effects of clearing the head, eliminating thirst, resolving phlegm, digesting food, strengthening the spleen and removing dampness, clearing away heat and detoxifying, and replenishing qi. It has an auxiliary therapeutic effect on patients with weak spleen and stomach and accumulated heat in the body. It is the adjuvant. Chongyang wood, Saishan indigo, white apricot, tortoise shell, northern bean root, hawthorn, camellia pollen, all the medicines are in harmony, and play the role of replenishing qi and blood, nourishing yin and suppressing yang, eliminating thirst and heat, and clearing heat and detoxifying.

[0025] The present invention discloses the following technical effects:

[0026] The invention provides a traditional Chinese medicine composition for treating type 2 diabetes caused by deficiency of both qi and yin. The prescription comprises hollyhockwood, indigofera serrata, white apricot, tortoise shell, northern bean root, hawthorn and camellia pollen. Through reasonable compatibility, the medicine complies with the treatment principle of "monarch, minister, assistant and envoy" compatibility, and synergistically plays the functions of replenishing qi and blood, nourishing yin and suppressing yang, relieving thirst and heat in the middle, and clearing away heat and detoxifying.

[0027] Clinical results show that the weight ratio of each component of the Chinese medicine preparation of the present invention has a good therapeutic effect, has a significant therapeutic effect on type 2 diabetes with deficiency of both qi and yin, with an effective rate of up to 68-74%, and has an equivalent or better therapeutic effect than traditional Western medicine, proving that the Chinese medicine composition prepared by the present invention can completely replace traditional Western medicine for the treatment of diabetic diseases; the present invention provides a practical new drug for the efficient treatment of patients with type 2 diabetes with deficiency of both qi and yin. DETAILED DESCRIPTION

[0028] Various exemplary embodiments of the present invention will now be described in detail. This detailed description should not be considered as limiting the present invention, but should be understood as a more detailed description of certain aspects, features, and embodiments of the present invention.

[0029] It should be understood that the terms described in the present invention are only for describing a particular embodiment and are not intended to limit the present invention. In addition, for the numerical range in the present invention, it should be understood that each intermediate value between the upper and lower limits of the scope is also specifically disclosed. The intermediate value in any stated value or stated range, and each smaller range between any other stated value or intermediate value in the described range is also included in the present invention. The upper and lower limits of these smaller ranges can be independently included or excluded in the scope.

[0030] Unless otherwise indicated, all technical and scientific terms used herein have the same meanings as those generally understood by those skilled in the art. Although the present invention describes only preferred methods and materials, any methods and materials similar or equivalent to those described herein may also be used in the implementation or testing of the present invention. All documents mentioned in this specification are incorporated by reference to disclose and describe the methods and / or materials associated with the documents. In the event of a conflict with any incorporated document, the content of this specification shall prevail.

[0031] It will be apparent to those skilled in the art that various modifications and variations may be made to the specific embodiments of the present invention description without departing from the scope or spirit of the present invention. Other embodiments derived from the present invention description will be apparent to those skilled in the art. The present invention description and examples are exemplary only.

[0032] The words “include,” “including,” “have,” “contain,” etc. used in this document are open-ended terms, meaning including but not limited to.

[0033] Example 1

[0034] A traditional Chinese medicine composition for treating diabetes comprises the following components in weight: 20g of Sophora flavescens, 17g of Indigofera serrata, 12g of Prunus armeniaca, 10g of Plastrum testudinis, 6g of Rhizoma Atractylodis Macrocephalae, 3g of Crataegus pinnatifida, and 1g of Camellia sinensis pollen.

[0035] Preparation method:

[0036] S1. Weigh the specified amount of Polygonum multiflorum, Indigofera serrata, Prunus armeniaca, Psoralea corylifolia, Rhizoma Psoralea corylifolia, Crataegus pinnatifida, Camellia sinensis powder, add 8 times the volume of pure water to decoct, boil and simmer for 40 minutes, then filter and collect the first decoction filtrate;

[0037] S2. Add the same amount of water as the first decoction to the filtered residue, perform a second decoction under the same conditions as the first decoction, and collect the second decoction filtrate;

[0038] S3. The filtrates obtained from the two decoctions are combined to obtain a Chinese medicine composition for treating diabetes.

[0039] Example 2

[0040] A traditional Chinese medicine composition for treating diabetes comprises the following components in weight: 18g of Sophora flavescens, 20g of Indigofera serrata, 10g of Prunus armeniaca, 16g of Plastrum testudinis, 7g of Rhizoma Atractylodis Macrocephalae, 2g of Crataegus pinnatifida, and 1g of Camellia sinensis pollen.

[0041] Preparation method:

[0042] S1. Weigh the specified amount of Polygonum multiflorum, Indigofera serrata, Prunus armeniaca, Psoralea corylifolia, Rhizoma Cynomorii, Crataegus pinnatifida, Camellia sinensis powder, add 5 times the volume of pure water to decoct, boil and simmer for 30 minutes, then filter and collect the first decoction filtrate;

[0043] S2. Add the same amount of water as the first decoction to the filtered residue, perform a second decoction under the same conditions as the first decoction, and collect the second decoction filtrate;

[0044] S3. The filtrates obtained from the two decoctions are combined to obtain a Chinese medicine composition for treating diabetes.

[0045] Example 3

[0046] A traditional Chinese medicine composition for treating diabetes comprises the following components in weight: 23g of Polygonum multiflorum, 20g of Indigofera serrata, 15g of Prunus armeniaca, 12g of Carapax tortoise shell, 5g of Rhizoma Cynoglossi, 4g of Crataegus pinnatifida, and 2g of Camellia sinensis powder.

[0047] Preparation method:

[0048] S1. Weigh the specified amount of Polygonum multiflorum, Indigofera serrata, Prunus armeniaca, Psoralea corylifolia, Rhizoma Psoralea corylifolia, Crataegus pinnatifida, Camellia sinensis powder, add 6 times the volume of pure water to decoct, boil and simmer for 50 minutes, then filter and collect the first decoction filtrate;

[0049] S2. Add the same amount of water as the first decoction to the filtered residue, perform a second decoction under the same conditions as the first decoction, and collect the second decoction filtrate;

[0050] S3. The filtrates obtained from the two decoctions are combined to obtain a Chinese medicine composition for treating diabetes.

[0051] Comparative Example 1

[0052] The same as Example 1, the only difference is that the Chinese medicine composition includes the following components in weight: 10g of Sophora flavescens, 12g of Indigofera sutchuenensis, 20g of Prunus armeniaca, 17g of Tortoise Shell, 1g of Rhizoma Atractylodis Macrocephalae, 6g of Crataegus pinnatifida, and 3g of Camellia sinensis powder. The compatibility principle of the Chinese medicine composition is to use Prunus armeniaca and Tortoise Shell as the main medicines, Sophora flavescens and Indigofera sutchuenensis as the ministerial medicines, Crataegus pinnatifida and Camellia sinensis powder as the adjuvant medicines, and Rhizoma Atractylodis macrocephalae as the guiding medicine.

[0053] Comparative Example 2

[0054] The same as Example 1, the only difference is that the blueberry is replaced by Schisandra chinensis.

[0055] Comparative Example 3

[0056] The same as Example 1, the only difference is that the northern bean root is adjusted to honeysuckle.

[0057] Clinical Validation

[0058] The Chinese medicine composition decoction prepared in Examples 1-3 of the present invention and Comparative Examples 1-3 was used in a clinical research scheme:

[0059] 1 Case selection criteria

[0060] (1) Volunteers who participated in the trial and took Chinese medicine for 4 weeks; (2) Aged 30 to 80 years; (3) Those who had not taken other Chinese medicine or used insulin in the past 2 weeks; (4) Patients and their families agreed and signed the informed consent form.

[0061] 2 Exclusion criteria

[0062] (1) Patients with acute complications of diabetes within the past month, such as ketoacidosis, hyperosmolar coma, and lactic acidosis; (2) Patients with serious diseases of the cardiovascular, liver, kidney, and hematopoietic systems; (3) Patients with serious mental illnesses who are unable to cooperate with treatment and evaluation; (4) Patients who are allergic to traditional Chinese medicine, those who do not use the medicine strictly as required, and those who are taking other traditional Chinese medicines.

[0063] 3. Elimination criteria

[0064] (1) Those who were misdiagnosed because they did not meet the inclusion criteria; (2) Those who did not strictly follow the protocol; (3) Those whose data were incomplete, affecting the effective clinical judgment; (4) Those who had adverse reactions such as allergies during treatment.

[0065] 4 Treatment methods

[0066] Basic treatment: (1) diabetes education; (2) oral hypoglycemic drugs and complication treatment were given according to the actual blood sugar of the patient with reference to the "Guidelines for the Prevention and Treatment of Type 2 Diabetes in China (2020 Edition)". The control group (n = 50) was given basic treatment; the Chinese medicine group was randomly divided into 1-6 groups (50 patients in each group), and the Chinese medicine compositions prepared by Examples 1-3 and Comparative Examples 1-3 were respectively used for oral treatment, 1 dose per day, 2 times a day, and 30 days as a course of treatment; the combined group (n = 50) was treated with the Chinese medicine composition of Example 1 on the basis of basic treatment, 1 dose per day, 2 times a day, and 30 days as a course of treatment.

[0067] 5 Diagnostic criteria

[0068] 5.1 Western medicine diagnostic criteria

[0069] Refer to the "Guidelines for the Prevention and Treatment of Type 2 Diabetes in China (2020 Edition)".

[0070] 5.2 TCM diagnostic criteria

[0071] The TCM syndrome differentiation standard is formulated with reference to the syndrome differentiation standard for qi and yin deficiency in the "Guidelines for Clinical Research of New Chinese Medicines". Main symptoms: dry throat and dry mouth, fatigue and weakness; secondary symptoms: thirst and love to drink, easy hunger after eating a lot, shortness of breath and laziness to speak, fever in the five hearts, palpitations and insomnia, red urine and constipation; red tongue with little fluid, thin and weak pulse. The syndrome can be differentiated if the two main symptoms, three secondary symptoms and tongue and pulse are met.

[0072] 5.3 TCM symptom classification standards

[0073] The following standards were established in accordance with the Technical Guiding Principles for Clinical Research on New Drugs (Traditional Chinese Medicine) for the Treatment of Diabetes Mellitus: (1) Severe: The patient actively emphasizes the prominent symptoms to the doctor, which is scored as 3 points; (2) Moderate: The patient can name the more prominent symptoms after being asked, which is scored as 2 points; (3) Mild: The symptoms are mild and only occur occasionally, which is scored as 1 point; (4) No symptoms: scored as 0 points.

[0074] 6 Observation indicators and methods

[0075] 6.1 TCM symptom improvement score

[0076] An assessment was conducted before and after treatment; the TCM symptom improvement assessment criteria refer to the "Guidelines for Clinical Research of New Chinese Medicines". Qi and Yin Deficiency Syndrome Scoring: Observe the symptoms before and after treatment: dry throat and mouth, fatigue, fever in the five hearts, palpitations and insomnia, constipation, and score 0, 2, 4, and 6 points according to none, mild, moderate, and severe. The higher the score, the more severe the symptom. Symptom score reduction rate = (symptom score before treatment - symptom score after treatment) / symptom score before treatment × 100%.

[0077] 6.2 Criteria for determining efficacy

[0078] (1) Cured: TCM symptom score reduction ≥ 95%, indicating that clinical symptoms and signs disappear or basically disappear; (2) Markedly effective: 70% ≤ TCM symptom score reduction < 95%, indicating that clinical symptoms and signs are significantly improved; (3) Effective: 30% ≤ TCM symptom score reduction < 70%, indicating that clinical symptoms and signs are improved; (4) Ineffective: TCM symptom score reduction < 30%, indicating that clinical symptoms and signs are not significantly improved or even aggravated. Total effective rate = (cured + markedly effective + effective) cases / total cases × 100%.

[0079] 6.3 Sugar metabolism index

[0080] 3 mL of peripheral blood was drawn from patients before and after treatment for FBG and 2h PBG testing.

[0081] 6.4 Adverse events

[0082] During each follow-up visit, the patient's adverse events were observed and recorded, and judged and handled.

[0083] 7 Experimental results

[0084] 7.1 Clinical efficacy

[0085] Table 1 Clinical efficacy of each group of patients

[0086] Group get well Significant effect efficient invalid Total effective rate (%) Control group 3 10 19 18 64 Example 1 9 13 12 16 68 Example 2 8 16 11 15 70 Example 3 11 14 12 13 74 Comparative Example 1 0 9 13 28 44 Comparative Example 2 2 11 13 24 52 Comparative Example 3 4 15 10 21 58 Experimental combination group 16 21 11 2 96

[0087] It can be seen from Table 1 that the Chinese medicine composition of Examples 1-3 prepared by the present invention has a good therapeutic effect on diabetic patients, with an effective rate of up to 68-74%, which is equivalent to or better than the Western medicine treatment in the control group, proving that the Chinese medicine composition prepared by the present invention can completely replace traditional Western medicine to treat diabetes. And the therapeutic effect of combining traditional Western medicine and Chinese medicine composition is as high as 96%, which is significantly better than the control group. However, the comparative examples 1-3 have significantly decreased efficacy due to the adjustment of the "monarch, minister, assistant and messenger" compatibility principle and monarch and messenger drug components of the Chinese medicine composition.

[0088] 7.2 TCM Syndrome Score

[0089] Before treatment, the TCM syndrome scores of each group of patients were tested. The statistical results showed that the scores of each symptom of the untreated diabetic patients were approximately: dry throat and dry mouth 180 points, fatigue 160 points, no heart and irritability 176 points, palpitations and insomnia 190 points, and constipation 200 points. The statistical results of the TCM syndrome scores of the patients after treatment in each group are as follows:

[0090] Table 2 TCM syndrome scores of patients in each group

[0091] Group Time Node Dry throat and mouth Fatigue and fatigue No worries Palpitations and insomnia constipate Control group After treatment 82 64 76 92 88 Example 1 After treatment 36 44 52 58 64 Example 2 After treatment 38 52 46 60 62 Example 3 After treatment 32 48 50 64 56 Comparative Example 1 After treatment 102 94 110 106 144 Comparative Example 2 After treatment 96 78 66 100 98 Comparative Example 3 After treatment 74 56 64 84 72 Experimental combination group After treatment 16 18 20 10 12

[0092] It can be seen from Table 2 that compared with before treatment, the symptom scores of each group after treatment were significantly reduced, but compared with the control group, the symptom scores of Examples 1-3 and the experimental combination group were reduced more significantly, indicating that the Chinese medicine composition prepared by the present invention has an effective therapeutic effect on improving diabetes.

[0093] 7.3 Sugar metabolism indicators

[0094] The glucose metabolism indexes of each group of patients were tested before treatment. The statistical results showed that the glucose metabolism indexes of the untreated diabetic patients were approximately: FBG 9.0mmol / L, 2h PBG 13.0mmol / L. The statistical results of the glucose metabolism indexes of the patients after treatment in each group are as follows:

[0095] Table 3 Glucose metabolism indicators of patients in each group

[0096] Group Time Node FBG (mmol / L) 2hPBG (mmol / L) Control group After treatment 8.2 11.4 Example 1 After treatment 7.6 10.9 Example 2 After treatment 7.8 10.6 Example 3 After treatment 7.5 10.7 Comparative Example 1 After treatment 8.6 12.4 Comparative Example 2 After treatment 8.4 11.5 Comparative Example 3 After treatment 8.1 11.0 Experimental combination group After treatment 6.0 9.2

[0097] It can be seen from Table 3 that compared with before treatment, the blood sugar levels of each group after treatment were significantly reduced, but compared with the control group, the blood sugar indexes of Examples 1-3 and the experimental combination group were reduced more significantly, indicating that the Chinese medicine composition prepared by the present invention has a significant therapeutic effect in improving blood sugar in diabetic patients.

[0098] The embodiments described above are only descriptions of the preferred modes of the present invention, and are not intended to limit the scope of the present invention. Without departing from the design spirit of the present invention, various modifications and improvements made to the technical solutions of the present invention by ordinary technicians in this field should all fall within the protection scope determined by the claims of the present invention.

Claims

1. A Chinese medicine composition for treating type 2 diabetes, characterized in that: Made from the following components in parts by weight: 18-23 parts of Chinese bunge, 17-20 parts of indigofera serrata, 10-15 parts of white apricot, 10-16 parts of tortoise shell, 5-7 parts of northern bean root, 2-4 parts of hawthorn and 1-2 parts of camellia pollen.

2. The Chinese medicine composition according to claim 1, characterized in that: Made from the following components in parts by weight: 23 parts of Radix Dipterocarpis, 20 parts of Indigofera serrata, 15 parts of Prunus armeniaca, 12 parts of Carapax testudinis, 5 parts of Rhizoma Atractylodis Macrocephalae, 4 parts of Fructus Crataegi and 2 parts of Camellia pollen.

3. A method for preparing the Chinese medicine composition according to claim 1 or 2, characterized in that: The following steps are involved: S1. Weigh a specified amount of components, add water and boil, and then filter and collect the first decoction filtrate; S2. Add water to the filtered residue and boil it, collecting the second decoction filtrate; S3. Combine the filtrates obtained from the two decoctions.

4. The preparation method according to claim 3, characterized in that: The step of adding water and decocting is to boil the water and then simmer over low heat for 30-50 minutes.

5. Use of the Chinese medicine composition as claimed in claim 1 or 2 in preparing a drug for treating type 2 diabetes.

6. The use according to claim 5, characterized in that: The medicament further comprises a pharmaceutically acceptable carrier.

7. The use according to claim 6, characterized in that: The carrier includes one or more of an excipient, an emulsifier and a surfactant.

8. The use according to claim 5, characterized in that: The dosage form of the drug includes tablets, capsules or decoctions.