A low-residue inhalation drug delivery device

Abstract

The invention discloses a low-residue inhalation drug delivery device, comprising a base, a cutting piece and a suction nozzle cover plate arranged on the base, a suction nozzle is arranged on the upper surface of the suction nozzle cover plate; a capsule bin for accommodating capsules is arranged on the base, and when the suction nozzle cover plate is covered, the capsule bin is located directly below the suction nozzle; an air inlet needle that can penetrate the capsule is arranged at the bottom of the capsule bin; a suction nozzle is arranged on the suction nozzle cover plate, and a grid or a grid plate is arranged at the bottom of the suction nozzle; the cutting piece is forced to reciprocate along the base from one end of the base to the suction nozzle direction of the other end; a cutter for cutting the capsule is arranged at one end of the cutting piece, and a drug through hole is arranged on the cutting piece for the drug to pass through. The drug delivery device provided by the invention, when used, the capsule is placed vertically, the cutter cuts the capsule shell horizontally, the cutting opening is large, the drug powder channel is unobstructed and unobstructed, and compared with traditional acupuncture, the drug powder residue in the capsule shell is greatly reduced; the cutting piece body is provided with a drug through hole, and after the cutting is completed, the drug through hole is concentric with the capsule bin and the suction nozzle, and will not block the drug delivery, further reducing the drug residue; the air inlet needle structure ventilates the capsule shell from bottom to top, further ensuring that there is no drug powder residue in the capsule shell.

Description

Technical Field

[0001] The invention belongs to the technical field of inhalation drug delivery devices, and in particular relates to a low-residue inhalation drug delivery device. Background Art

[0002] Dry powder inhaler is a micronized aerosol without propellant. The micronized drug or carrier is in the form of capsules, blisters or multi-dose reservoirs, and is inhaled actively by the patient using a special dry powder inhaler device. The development of dry powder inhalers depends largely on the research of the device.

[0003] The existing inhaler adopts the method of piercing the capsule to open (CN1953779A and CN116637256A), the opening is small, and more medicine powder remains in the capsule after inhalation.

[0004] The inhalation drug delivery device provided by CN219481159U is cut by a cutter. Since the capsule remains in the device after cutting, when the capsule diameter is consistent with the diameter of the drug storage cavity and the height is higher than the cutter, the upper passage is completely blocked because the upper part of the capsule shell is not cut, and thus the device cannot be used; when the capsule diameter is consistent and the height is less than or equal to the cutter, since the capsule shell is still in the drug storage cavity and the powder is distributed in the movable groove and the cut capsule shell, the existence of the capsule shell causes the powder delivery passage to be blocked, which is not conducive to the blowing out of the powder; in addition, regardless of the size of the capsule, due to the existence of airflow dead corners in the device, more powder will remain.

[0005] The nasal powder medicine dispensing device provided by CN1838974A cuts the capsule at the upper and lower parts simultaneously, and more medicine powder will be stored in the lower part of the cut capsule, resulting in the waste of medicine powder in the capsule shell whose lower part is cut off.

[0006] How to reduce the residual drug powder in the capsule and avoid the loss of drug powder during the cutting process are problems that still need to be solved in inhalation drug delivery devices. Summary of the invention

[0007] In order to solve the above problems in the prior art, the present invention provides a low-residue inhalation drug delivery device, which can significantly reduce the drug residue in the capsule and the inhalation device. In order to achieve this effect, the technical solution provided by the present invention is as follows:

[0008] A low-residue inhalation drug delivery device, comprising:

[0009] A base, and a cutting piece and a nozzle cover plate arranged on the base, wherein a nozzle is arranged on the upper surface of the nozzle cover plate;

[0010] A capsule bin for accommodating capsules is arranged on the base, and when the nozzle cover is closed, the capsule bin is located directly below the nozzle;

[0011] An air inlet needle capable of piercing the capsule is arranged at the bottom of the capsule compartment; a suction nozzle is arranged on the suction nozzle cover plate, and a grid or a grating is arranged at the bottom of the suction nozzle;

[0012] The cutting piece is forced to reciprocate along the base from one end of the base to the direction of the suction nozzle at the other end; a cutter for cutting capsules is arranged at one end of the cutting piece, and a medicine through hole is arranged on the cutting piece for medicine to pass through.

[0013] Preferably, the inner diameter of the drug through hole is not smaller than the opening of the capsule bin or the cover plate through hole or the opening of the suction nozzle; the position of the drug through hole is such that when the cutting piece body is located at the leftmost end, the drug through hole, the suction nozzle, the cover plate through hole, and the capsule bin are located on the same center line, and the drug through hole is tightly connected to the upper edge of the capsule bin below it and the lower edge of the suction nozzle above it, so as to achieve a mechanical sealing effect.

[0014] Preferably, one side of the nozzle cover is connected to the base via a hinge or a hinge, and the opposite side is connected to the base via a buckle; alternatively, the nozzle cover is fixed to the base, in which case the nozzle and the nozzle cover are detachably connected.

[0015] Preferably, the cutting member includes a cutting member body, a cutting knife is arranged on the cutting member body of the cutting plate; the lower surface of the cutting knife and the lower surface of the cutting member body are located at the same horizontal plane; the length and width of the cutting portion of the cutting knife are both greater than or equal to the diameter of the capsule to be cut; cutting member sliders are arranged at both ends of the cutting member body, and a cutting member sliding groove for accommodating the cutting member slider is arranged on the base. In order to prevent the cutting member body from sliding out, the end of the sliding groove is blocked; the capsule bin fixing cavity is used to fix the capsule bin.

[0016] Preferably, a driving mechanism for driving the cutting member to move is further provided, and the driving mechanism comprises a pull rod, a limiting protrusion, an excitation spring and an excitation member;

[0017] As an implementation mode, a fixed cover plate fixed to the base is provided next to the nozzle cover plate, a pull rod limiting groove opening toward the nozzle cover plate is provided on the fixed cover plate, the pull rod is located on the upper surface of the cutting piece body, the upper end of the pull rod passes through the pull rod limiting groove of the fixed cover plate, and the top end of the pull rod is located outside the base; the limiting protrusion is located on the lower surface of the cutting piece body; one end of the excitation spring is fixed to the cutting piece body, and the other end is fixed to the side of the base away from the nozzle, and the excitation spring is a compression spring;

[0018] The excitation member includes a fixed block and an excitation block. The excitation member fixed block is a U-shaped structure. A blocking block is arranged at one end of the excitation block to cooperate with the limiting protrusion for blocking the limiting protrusion, and an excitation rod is arranged at the other end. The excitation block is rotatably arranged on the fixed block through a pin shaft, and a vertical positioning spring is arranged on the inner side of the excitation block.

[0019] Preferably, the capsule compartment is detachably connected to the base.

[0020] As an embodiment, the capsule bin is composed of a body and an adjustable bottom groove detachably connected thereto; an air inlet needle and a fixing hole for the air inlet needle to pass through are arranged at the bottom of the adjustable bottom groove, and the air inlet needle includes an air outlet portion at the top and an air inlet rod connected to the bottom of the air outlet portion. The capsule bin is designed as a detachable structure to accommodate capsules of different widths, and the adjustable bottom groove is arranged to accommodate capsules of different heights.

[0021] Preferably, the outlet portion of the air inlet needle includes several layers of cones with cavities, the adjacent layers of cones are connected to each other, the top of the top cone is sealed, and the bottom opening is used as an outlet hole for gas discharge, and the other layers are cones or truncated cones. The end of the air inlet needle is an elongated cylinder, which can completely block the hole pierced by the air inlet needle to prevent the powder from flowing out. The outlet hole of the air inlet needle is opened downward. When in use, the capsule is placed in the capsule compartment and pressed downward so that after the air inlet needle pierces the capsule, the powder will not leak out through the hole.

[0022] As an embodiment, an arc-shaped exhaust channel is provided on the inner wall of the vertebral body of the air inlet needle, or an arc-shaped groove or arc-shaped protrusion extending outward is provided on the inner wall of the air inlet needle to form a spiral airflow, so that the airflow in the capsule rotates, further reducing the residual medicinal powder in the capsule.

[0023] Preferably, a capsule shell outlet groove is provided on the outer side of the nozzle cover plate to facilitate the discharge of the cut capsule shell from the drug delivery device.

[0024] Before the cutting piece body is activated, the pull rod is pulled to the right side of the limiting groove, and the blocking block blocks the limiting protrusion to fix the position; at this time, the compression spring is compressed by the cutting piece body and the base, and has a tendency to stretch; when in use, the activation rod of the activation block is pushed, and driven by the compression spring, the cutting piece body slides rapidly to the left, cutting off the upper part of the capsule shell in the capsule compartment, and throwing the capsule shell out of the inhaler under the action of inertia.

[0025] Then, the patient inhales through the nozzle, and air is introduced into the capsule through the air inlet needle. The dry drug powder flows upward under the action of the airflow and is delivered to the patient through the nozzle.

[0026] Compared with the prior art, the present invention has the following beneficial effects:

[0027] 1. When the drug delivery device provided by the present invention is used, the capsule is placed vertically, and the cutter cuts the capsule shell horizontally. The cutting opening is large, and the medicine powder passage is unobstructed without dead corners. Compared with traditional acupuncture, the residual medicine powder in the capsule shell is greatly reduced; because only the part without medicine powder on the upper part of the capsule is cut off, compared with the prior art, the cutting will not cause the loss of medicine powder.

[0028] 2. The cutting piece provided by the present invention has a drug through hole on its body. After cutting is completed, the drug through hole is concentric with the capsule bin and the nozzle, and will not block drug delivery, thereby further reducing drug residue. The drug through hole is tightly connected to the upper edge of the capsule bin below it and the lower edge of the nozzle above it, achieving a mechanical sealing effect, good air tightness, and more stable airflow.

[0029] 3. The present application designs an air inlet needle structure, which ventilates the capsule shell from bottom to top, further ensuring that there is no drug powder residue in the capsule shell; the air outlet of the air inlet needle opens downward to prevent drug powder from flowing out of the air inlet needle when pierced. The end of the air inlet needle is set to be an elongated cylinder, which can completely block the hole pierced by the air inlet needle to prevent drug powder from flowing out.

[0030] 4. The present application is designed with a movable cover. Before use, the pull rod is pulled to pull the cutting member body to the initial state, the cover is opened to place the capsule in the capsule bin and fix it, and then the nozzle cover is closed, and the trigger member is operated to cut the capsule shell with a cutter. The operation is simple, hygienic and convenient.

[0031] 5. The present application designs an adjustable bottom groove to adjust the height of the capsule bin to accommodate capsules of different heights; the detachable capsule bin can be suitable for capsules of different outer diameters, and the present structure has good versatility.

[0032] 6. The present application designs a capsule shell outlet groove on the nozzle cover plate, so that the capsule shell can be discharged from the inhaler more smoothly. BRIEF DESCRIPTION OF THE DRAWINGS

[0033] The accompanying drawings in the specification, which constitute a part of the present invention, are used to provide a further understanding of the present invention. The exemplary embodiments of the present invention and their descriptions are used to explain the present invention and do not constitute improper limitations on the present invention.

[0034] Figure 1 This is an external structural diagram of a low-residue inhalation drug delivery device provided in Example 1 of the present application;

[0035] Figure 2 This is a structural explosion diagram of a low-residue inhalation drug delivery device provided in Example 1 of the present application;

[0036] Figure 3 This is an external structural diagram of a low-residue inhalation drug delivery device provided in Example 2 of the present application;

[0037] Figure 4 A structural diagram of a low-residue inhalation drug delivery device provided in Example 2 of the present application in an open state of a nozzle cover;

[0038] Figure 5 A cross-sectional view from a main perspective of a low-residue inhalation drug delivery device provided in Example 2 of the present application;

[0039] Figure 6An exploded diagram of the structure of a low-residue inhalation drug delivery device provided in Example 2 of the present application;

[0040] Figure 7 An exploded diagram of the capsule compartment structure in a low-residue inhalation drug delivery device provided in Example 2 of the present application;

[0041] Figure 8 A schematic diagram of the structure of an air inlet needle in a low-residue inhalation drug delivery device provided in Example 2 of the present application;

[0042] Fig. 9 A schematic diagram of another air inlet needle structure in a low-residue inhalation drug delivery device provided in Example 2 of the present application;

[0043] Fig.10 This is a schematic diagram of the structure of an arc-shaped exhaust duct for an air inlet needle in a low-residue inhalation drug delivery device provided in Example 2 of the present application.

[0044] Among them, 1- nozzle, 2- cover plate, 3- cutting piece, 4- base;

[0045] 21-fixed cover plate, 22-nozzle cover plate;

[0046] 31-cutting element body, 32-pull rod, 33-limiting protrusion, 34-excitation spring, 35-excitation element;

[0047] 41-base body, 42-capsule compartment, 43-excitation member fixing slot, 44-cutting member sliding slot;

[0048] 2101-tie rod limit slot;

[0049] 2201-capsule shell outlet slot;

[0050] 3101-cutter, 3102-cutting piece slider, 3103-drug through hole;

[0051] 3501-fixed block, 3502-excitation block, 3503-blocking block, 3504-excitation rod, 3505-positioning spring;

[0052] 4101-limiting convex sliding groove, 4102-capsule compartment fixing cavity, 4103-magnetic fixing ring;

[0053] 4201-capsule bin limiting ring, 4202-capsule bin body, 4203-adjustable bottom groove, 4204-inlet needle, 4205-fixing hole, 4206-outlet part, 4207-inlet rod, 4208-exhaust duct. DETAILED DESCRIPTION

[0054] It should be noted that the following detailed descriptions are exemplary and are intended to provide further explanation of the present invention. Unless otherwise specified, all technical and scientific terms used herein have the same meanings as those commonly understood by those skilled in the art to which the present invention belongs.

[0055] It should be noted that the terms used herein are only for describing specific embodiments and are not intended to limit exemplary embodiments according to the present invention. As used herein, unless the context clearly indicates otherwise, the singular form is also intended to include the plural form. In addition, it should be understood that when the terms "comprising" and / or "including" are used in this specification, it indicates the presence of features, steps, operations, devices, components and / or combinations thereof.

[0056] Example 1, a low-residue inhalation drug delivery device

[0057] like Figure 1 , Figure 2 As shown, it includes a suction nozzle 1, a cover plate 2, a cutting piece 3 and a base 4.

[0058] The suction nozzle 1 can be integrally formed with the cover plate 2, or fixed to the cover plate 2 by threaded connection, bonding or clamping. A through hole is set on the cover plate 2 at the position of the suction nozzle 1, and the suction nozzle 1 and the through hole on the cover plate 2 are located on the same center line.

[0059] A grid or a grid plate is provided at the bottom of the suction nozzle 1, and the grid or the grid plate can be integrally formed with the suction nozzle or can be detachable; when the grid or the grid plate is detachable, a fixed ring is provided around it, and a corresponding slot is provided under the suction nozzle. The ring can be inserted into the slot for convenient installation, removal or tilting, and it is also convenient to replace different grids to achieve a better suction effect or replace the grid when it is damaged.

[0060] The cover plate 2 and the base 4 are connected by a hinge or a hinge; the lower surface of the cover plate 2 is provided with a capsule shell outlet groove 2201 away from the suction nozzle 1. One side of the cover plate is connected to the base by a hinge or a hinge, and the opposite side is connected to the base by a buckle; the buckle is opened, the cover plate is opened, and the capsule can be placed in the base capsule compartment of the size suitable for the capsule, and the cover plate is closed. The mesh or grid on the cover plate presses the capsule downward, so that the air inlet needle at the bottom of the capsule compartment penetrates the capsule, and the buckle is buckled, and the capsule is fixed in the inhalation drug delivery device.

[0061] Cutting piece sliders 3102 are provided on both sides of the cutting piece 3, a cutting knife 3101 is provided at one end, and a pull rod 32 is provided at the other end.

[0062] The base 4 includes a base body 41, a cutting piece sliding groove 44 and a capsule compartment 42 arranged on the base body 41. The capsule compartment 42 is integral with the base or detachable. An air intake needle is provided at the bottom of the capsule compartment 42 (the capsule compartment structure is not shown and is the same as the structure in Example 2).

[0063] When in use, open the cover plate 2, put the capsule into the capsule bin, cover the cover plate 2, and use the buckle to lock the cover plate 2 to the base. When the cover plate is covered, the capsule is squeezed by the cover plate and moves downward, so that the air intake needle pierces the capsule shell. At this time, align the cutting piece slider 3102 on the cutting piece with the cutting piece sliding groove 44 on the base from the side near the capsule bin 42, and push the pull rod 32 with your fingers to make the cutting piece cut the capsule. When the cutting piece pull rod 32 contacts the cover plate 2, the medicine through hole on the cutting piece is airtightly connected with the upper edge of the capsule bin 42 below it and the lower edge of the suction nozzle above it. At this time, the patient inhales through the suction nozzle, and the air enters from the air intake needle to achieve air circulation, and the powder can be inhaled.

[0064] As another embodiment, when the cover plate 2 is fixed to the base 4 by screws or bonding, the cover plate cannot move relative to the base. The suction nozzle 1 can be fixed to the cover plate 2 by threaded connection or clamping, and a through hole is set on the cover plate 2 at the position of the suction nozzle 1. When in use, the suction nozzle is removed from the cover plate, the capsule is placed into the capsule cavity through the through hole on the cover plate 2, and the suction nozzle is installed on the cover plate 2, the suction nozzle is connected, and the grid or grid plate at the bottom of the suction nozzle presses the capsule downward, so that the air intake needle at the bottom of the capsule compartment 42 penetrates the capsule. At this time, the cutting piece slider 3102 on the cutting piece is aligned with the cutting piece sliding groove 44 on the base from the side near the capsule compartment 42, and the pull rod is pushed with a finger to make the cutting piece cut the capsule. When the cutting piece pull rod contacts the suction nozzle cover plate, the medicine through hole on the cutting piece is tightly connected to the upper edge of the capsule compartment below it and the lower edge of the suction nozzle above it. At this time, the patient inhales through the suction nozzle, and air enters from the air intake needle, and the powder can be inhaled.

[0065] Example 2, a low-residue inhalation drug delivery device

[0066] Further improvements based on the structure of Example 1, such as Figure 3 and Figure 4 As shown, the cover plate 2 includes a fixed cover plate 21 and a nozzle cover plate 22, and the nozzle cover plate 22 is connected to the base 4 by a hinge or a hinge. The fixed cover plate 21 is adjacent to the nozzle cover plate 22 and is fixed to the base 4 by screws or bonding. The fixed cover plate 21 is provided with a pull rod limiting groove 2101 that opens toward the nozzle cover plate 22. The lower surface of the nozzle cover plate 22 is provided with a capsule shell outlet groove 2201 that is away from the nozzle 1.

[0067] The cutting member body 3 cuts off the capsule shell. When the upper portion of the capsule shell cut off reaches the left side of the suction nozzle, it no longer contacts the suction nozzle cover plate, so that the capsule shell is discharged from the suction device under the action of inertia.

[0068] like Figure 5As shown, the base 4 includes a base body 41 and a limiting protrusion sliding groove 4101, a capsule bin fixing cavity 4102, and a capsule bin 42, a magnetic fixing ring 4103 is arranged on the top of the capsule bin fixing cavity 4102, and the magnetic fixing ring 4103 is an annular magnet block. A capsule bin limiting ring 4201 is arranged on the top of the capsule bin 42, and the capsule bin limiting ring 4201 is made of magnetic material. When the capsule bin 42 is placed in the capsule bin fixing cavity 4102, the magnetic fixing ring 4103 of the capsule bin fixing cavity 4102 and the capsule bin limiting ring 4201 will be adsorbed together, thereby positioning the capsule bin 42 well.

[0069] The capsule bin fixed cavity 4102, the suction nozzle 1 and the through hole on the cover plate are located on the same center line and are interconnected.

[0070] like Figure 4 and Figure 5 As shown, the cutting member 3 is arranged between the base 4 and the cover plate 2, and includes a cutting member body 31, a pull rod 32, a limiting protrusion 33, an excitation spring 34, and an excitation member 35; the excitation member 35 includes a fixed block 3501 and an excitation block 3502, wherein the fixed block 3501 is a U-shaped structure, one end of the excitation block 3502 is provided with a blocking block 3503 which cooperates with the limiting protrusion 33 to block the limiting protrusion 33, and the other end is provided with an excitation rod 3504, the excitation block 3502 is rotatably arranged on the fixed block 3501 through a pin shaft, a vertical positioning spring 3505 is arranged on the inner side of the excitation block 3502, and the positioning spring 3505 is a compression spring, the top end of which contacts the excitation block 3502, and the bottom end contacts the fixed block 3501. Figure 4 and Figure 6 As shown, the cutting knife 3101 is in the middle of one end of the cutting piece body 31 facing the suction nozzle, and the other end of the cutting piece body 31 is fixedly connected to the pull rod 32 or formed as one piece. The upper end of the pull rod 32 passes through the pull rod limiting groove 2101 of the fixed cover plate 21, and the top end of the pull rod 32 is located outside the base 4, which is used to manually operate the pull rod 32 to change the position of the cutting piece body 31; the limiting protrusion 33 is located on the lower surface of the cutting piece body 31.

[0071] The cutting member body 31 is also provided with a drug through hole 3103. The position of the drug through hole 3103 is such that when the cutting member body 31 is activated and located at the leftmost end after cutting the capsule shell, the drug through hole 3103 is located on the same center line as the suction nozzle 1, the cover plate through hole, and the capsule chamber 42. The inner diameter of the drug through hole 3103 is not less than the opening of the capsule chamber 42 or the cover plate through hole or the opening of the suction nozzle 1, so as to avoid the cutting member body 31 blocking the delivery of the drug. The position of the drug through hole is such that when the cutting member body is located at the leftmost end after cutting the capsule shell, the drug through hole is located on the same center line as the suction nozzle, the cover plate through hole, and the capsule chamber, and there is no gap at the contact position, and sealing can be achieved by a sealing ring and other structures to prevent drug powder from leaking out.

[0072] Before use, the positioning spring 3505 is in an extended state, and the excitation spring 34 is in a compressed state, so that the blocking block 3503 of the excitation block 3502 blocks the limiting protrusion 33, so that the cutting piece 3 is located at the rightmost end; when in use, the excitation block 3502 is pushed to rotate around the pin shaft, and the blocking block 3503 no longer blocks the limiting protrusion 33, and the cutting piece body 31 pops out to the side of the suction nozzle under the elastic force of the excitation spring 34 to cut the capsule. When the cutting piece body 31 slides to the leftmost side of the device and stops moving, the medicine through hole on the cutting piece is tightly connected with the upper edge of the capsule bin below it and the lower edge of the suction nozzle above it; as a typical embodiment, by setting the length of each component, the cutting piece pull rod 32 is in contact with the suction nozzle cover plate 2 at this time; at this time, the patient inhales through the suction nozzle, and the air enters from the air inlet needle to realize air circulation, and the medicine powder can be inhaled. In order to achieve this effect, when the cutting piece body 31 slides to the leftmost side of the device, the excitation spring 34 used is in a natural state or still in a compressed state.

[0073] The base 4 is provided with a capsule bin fixing cavity 4102 below the suction nozzle, and an operating space for the cutting member 3 is provided at the other end, including an excitation member fixing groove 43 for fixing the excitation member fixing block 3501. The opening above the excitation member fixing groove 43 becomes smaller, providing space for the excitation block 3502 to rotate.

[0074] The top of the base 4 is provided with a cutting member sliding groove 44 along the length of the cutting member body 31 for the sliding guide of the cutting member slider 3102 of the cutting member body; in order to prevent the cutting member body 31 from sliding out and extending out of the inhalation medication device body to cut the user, the end of the cutting member sliding groove 44 is blocked; the compression spring 34 is composed of two pieces, symmetrically arranged on both sides of the cutting member body 31, one end of each piece is fixed to the cutting member body 31 and the other end is fixed to one side of the base 4. Before the cutting member body 31 is not excited, the pull rod 32 is pulled to the right side of the pull rod limiting groove 2101, and the blocking block 3503 blocks the limiting protrusion 33 to fix the position; at this time, the compression spring 34 is contracted by the cutting member body 31 and the base 4, and has a tendency to stretch; when in use, the excitation rod 3504 of the excitation block 3502 is pushed, and the blocking block 3503 no longer blocks the limiting protrusion 33. Driven by the compression spring 34, the cutting member body 31 slides rapidly to the left to cut off the upper part of the capsule shell in the capsule compartment 42.

[0075] The capsule bin 42 also includes a capsule bin body 4202 and an adjustable bottom groove 4203. The capsule bin limiting ring 4201 is integrally formed with or fixedly connected to the capsule bin body 4202, and the lower part is detachably connected to the adjustable bottom groove 4203 with an external thread through an internal thread.

[0076] The capsule bin 42 is designed as a detachable structure to accommodate capsules of different widths, and an adjustable bottom groove 4203 is provided to accommodate capsules of different heights.

[0077] like Figure 7 As shown, an air inlet needle 4204 and a fixing hole 4205 for the air inlet needle 4204 to pass through are arranged at the bottom of the adjustable bottom groove 4203. The air inlet needle 4204 includes an upper air outlet part 4206 and an air inlet rod 4207 connected to the bottom of the air outlet part. The air inlet rod is embedded in or fixed to the fixing hole 4205 at the bottom of the adjustable bottom groove 4203 by threaded connection. The bottom of the air inlet rod is connected to the outside of the device to achieve air circulation when the patient inhales.

[0078] As a further improvement to the structure, the structure of the air inlet needle 4204 is as follows: Figure 8 or Fig. 9 As shown, the outlet portion 4206 of the air inlet needle 4204 includes several layers of cones with cavities, and the adjacent layers of cones are connected to each other, which can be directly connected or connected through a connecting rod with a cavity; the top of the top cone is sealed, and the bottom is opened as an outlet hole for gas discharge, and the top and bottom of the other layers of cones are open, or they can be in the shape of a truncated cone. The diameter of the air inlet rod 4207 below the air outlet portion 4206 is not less than the outer edge of the cone or truncated cone of the air outlet portion 4206 above it, and can block the bottom hole of the capsule shell through which the air inlet needle 4204 passes, so as to prevent the outflow of medicine powder.

[0079] The air outlet hole of the air inlet needle is opened downwards. When in use, the capsule is placed in the capsule compartment and pressed downwards, so that after the air inlet needle pierces the capsule, the medicine powder will not leak out through the hole.

[0080] As a preferred method, Fig.10 As shown, the inner wall of the vertebral body of the air inlet needle is provided with an arc-shaped exhaust channel 4208; as another way, the inner wall of the vertebral body of the air inlet needle is provided with an arc-shaped groove or arc-shaped protrusion extending outward. After the inhaled air enters from the air inlet hole, it is discharged downward from the exhaust hole, and under the action of the spiral arc-shaped groove, it is blown into the capsule in a spiral direction, so that the airflow in the capsule rotates, further reducing the residual medicine powder in the capsule.

[0081] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. For those skilled in the art, the present invention may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A low-residue inhalation drug delivery device, characterized in that: include: A base, and a cutting piece and a nozzle cover plate arranged on the base, wherein a nozzle is arranged on the upper surface of the nozzle cover plate; A capsule bin for accommodating capsules is arranged on the base, and when the nozzle cover is closed, the capsule bin is located directly below the nozzle; An air inlet needle capable of piercing the capsule is arranged at the bottom of the capsule compartment; a grid or a grid plate is arranged at the bottom of the suction nozzle; The cutting member is forced to reciprocate along the base from one end of the base to the direction of the suction nozzle at the other end; a cutter for cutting capsules is provided at one end of the cutting member, and a drug through hole is provided on the cutting member for the drug to pass through; The cutting piece comprises a cutting piece body, and a cutter is arranged on the cutting piece body; the lower surface of the cutter and the lower surface of the cutting piece body are located in the same horizontal plane; the length and width of the cutting part of the cutter are both greater than or equal to the diameter of the capsule to be cut; A through hole is arranged on the nozzle cover at the position of the nozzle; The inner diameter of the drug through hole is not less than the capsule compartment opening or the nozzle cover through hole or the nozzle opening; A capsule shell outlet groove away from the suction nozzle is arranged on the lower surface of the suction nozzle cover plate.

2. The inhalation medication device according to claim 1, characterized in that: The position of the drug through hole is that when the cutting piece body is located at the far left end, the drug through hole, the suction nozzle, the cover plate through hole, and the capsule bin are located on the same center line, and the drug through hole is tightly connected to the upper edge of the capsule bin below it and the lower edge of the suction nozzle above it, achieving a mechanical sealing effect.

3. The inhalation medication device according to claim 1, characterized in that: One side of the nozzle cover is connected to the base through a hinge or a hinge, and the opposite side is connected to the base through a buckle; alternatively, the nozzle cover is fixed to the base, in which case the nozzle and the nozzle cover are detachably connected.

4. The inhalation medication device according to claim 1, characterized in that: Cutting piece slide blocks are arranged at both ends of the cutting piece body, and a cutting piece sliding groove for accommodating the cutting piece slide blocks is arranged on the base.

5. The inhalation medication device according to claim 4, characterized in that: A driving mechanism for driving the cutting member to move is also provided, and the driving mechanism includes a pull rod, a limiting convex block, an excitation spring and an excitation member; A fixed cover plate fixed to the base is provided next to the nozzle cover plate, a pull rod limiting groove opening toward the nozzle cover plate is provided on the fixed cover plate, the pull rod is located on the upper surface of the cutting piece body, the upper end of the pull rod passes through the pull rod limiting groove of the fixed cover plate, and the top end of the pull rod is located outside the base; the limiting protrusion is located on the lower surface of the cutting piece body; one end of the excitation spring is fixed to the cutting piece body, and the other end is fixed to the side of the base away from the nozzle, and the excitation spring is a compression spring; The excitation member includes a fixed block and an excitation block. The excitation member fixed block is a U-shaped structure. A blocking block is arranged at one end of the excitation block to cooperate with the limiting protrusion for blocking the limiting protrusion, and an excitation rod is arranged at the other end. The excitation block is rotatably arranged on the fixed block through a pin shaft, and a vertical positioning spring is arranged on the inner side of the excitation block.

6. The inhalation medication device according to any one of claims 1 to 5, characterized in that: The capsule compartment is detachably connected to the base.

7. The inhalation medication device according to claim 6, characterized in that: The capsule compartment consists of a main body and an adjustable bottom groove detachably connected thereto; an air intake needle and a fixing hole for the air intake needle to pass through are arranged at the bottom of the adjustable bottom groove, and the air intake needle includes an upper air outlet part and an air intake rod connected to the lower part of the air outlet part.

8. The inhalation medication device according to claim 7, characterized in that: The outlet part of the air inlet needle includes several layers of cones with cavities. The adjacent layers of cones are connected to each other. The top of the top cone is sealed, and the opening at the bottom serves as an outlet for gas discharge. The other layers are cones or frustum shapes.

9. The inhalation medication device according to claim 8, characterized in that: The inner wall of the cone of the air inlet needle is provided with an arc-shaped exhaust channel, or the inner wall of the air inlet needle is provided with an arc-shaped groove or arc-shaped protrusion extending outward.

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