A kind of impurity removal equipment for crude heparin sodium

Abstract

The invention relates to the technical field of sodium heparin impurity removal, in particular to a device for removing impurities from crude sodium heparin; the device comprises a body, an oscillating motor is installed on the upper end of the body; a shell is arranged above the body; the body and the shell are connected via an oscillating spring; three shells are arranged; the three shells are distributed up and down; two adjacent shells are rotatably connected; a filter plate is arranged between the two upper shells; the filter plate is connected to the shell; a guide plate is connected to the upper end of the filter plate; the device arranges a grinding roller in the shell so that the grinding roller can directly dry and crush the sieved sodium heparin block, thereby eliminating the need to transport the sieved sodium heparin block, and the grinding roller is located inside the shell, thereby reducing the contact between the sodium heparin block and external dust, preventing the sodium heparin powder from being contaminated, and improving the purity and quality of the sodium heparin.

Description

Technical Field

[0001] The invention relates to the technical field of heparin sodium impurity removal, in particular to a device for removing impurities from crude heparin sodium. Background Art

[0002] Heparin sodium is an anticoagulant that can interfere with many aspects of the blood coagulation process and has an anticoagulant effect both in vivo and in vitro. Its mechanism of action is relatively complex. It mainly binds to antithrombin III (AT-III) and enhances the latter's inhibitory effect on activated coagulation factors II, IX, X, XI and XII. Its consequences involve preventing platelet aggregation and destruction, hindering the formation of coagulation activating enzymes, preventing prothrombin from turning into thrombin, inhibiting thrombin, and thus hindering fibrinogen from turning into fibrin, thereby exerting an anticoagulant effect.

[0003] Most of the existing sodium heparin is extracted from the pig small intestinal mucosa. In the extraction process, multiple solvents are usually required to obtain the extract. Since the sodium heparin solution is relatively unstable in the liquid state, it is easily degraded and deteriorated by environmental factors. Drying it into a powder form can effectively extend its shelf life, reduce the risk of degradation, and make it easier to package and transport. Therefore, it is often necessary to dry the extract and grind the obtained dry product to collect the finished sodium heparin powder. Sodium heparin is a hygroscopic compound with strong hygroscopicity. It easily absorbs moisture in the air, causing the powdered sodium heparin to agglomerate or absorb moisture in a humid environment. The agglomerated sodium heparin not only has poor solubility, but also easily causes weighing errors during use, thereby affecting the accuracy of medication. Therefore, the sodium heparin powder needs to be screened.

[0004] In the prior art, a rotary vibrating screen is often used to screen the damp sodium heparin powder. The sieved sodium heparin block is often transported to a drying device for drying, and then the dried sodium heparin block is transported to a crushing device to crush the sodium heparin block into powder. In the process of transporting the sieved sodium heparin block to the drying device and the crushing device, impurities such as dust from the outside will inevitably come into contact with the sodium heparin block, especially for the crushing device. The dust from the outside is more likely to mix with the crushed sodium heparin powder, thereby causing the sodium heparin powder to be contaminated, thereby affecting the purity and quality of the sodium heparin.

[0005] In view of this, in order to overcome the above technical problems, the present invention proposes a crude heparin sodium impurity removal device to solve the above technical problems. Summary of the invention

[0006] In order to make up for the shortcomings of the prior art, the present invention proposes an impurity removal device for crude sodium heparin. The present invention arranges a grinding roller in a shell so that the grinding roller can directly dry and crush the sieved sodium heparin block, thereby eliminating the need to transport the sieved sodium heparin block. Moreover, the grinding roller is located inside the shell, thereby reducing the contact between the sodium heparin block and external dust, preventing the sodium heparin powder from being contaminated, and improving the purity and quality of the sodium heparin.

[0007] The technical solution adopted by the present invention to solve the technical problem is: the impurity removal equipment of crude heparin sodium described in the present invention comprises:

[0008] The machine body is provided with an oscillating motor at the upper end; a shell is provided above the machine body; the machine body and the shell are connected by an oscillating spring; there are three shells; the three shells are distributed up and down; two adjacent shells are rotatably connected; a filter plate is provided between the two upper shells; the filter plate is connected to the shell; a guide plate is connected to the upper end of the filter plate; a feed port, a block outlet, a powder outlet, a crushing port and a discharge port are provided on the surface of the shell in sequence from top to bottom;

[0009] A grinding roller, wherein a mounting plate is arranged inside the shell at the bottom; the mounting plate is fixedly connected to the shell; a turbine is rotatably connected to the upper end of the mounting plate; a worm meshing with the turbine is arranged on one side of the turbine; the worm is rotatably connected to the shell; a driving motor is installed on the outer wall of the shell; the driving motor is used to drive the worm to rotate; a mounting frame fixedly connected to the turbine is arranged at the lower end of the mounting plate; the grinding roller is rotatably connected to the lower end of the mounting frame.

[0010] Preferably, an annular plate is provided below the mounting plate; the annular plate is fixedly connected to the shell; a shovel plate is provided between the annular plate and the mounting frame; the shovel plate is fixedly connected to the mounting frame; and the shovel plate is arranged at an angle.

[0011] Preferably, an annular groove is provided inside the annular plate; an air inlet connected to the annular groove is provided on the outer wall of the shell; an air hole is provided on the inner wall of the shell; the air hole is connected to the annular groove; and an air blowing unit is installed in the annular groove.

[0012] Preferably, the blowing unit includes a push plate; a swivel is rotatably connected in the annular groove; the swivel is fixedly connected to the shovel plate; a sealing block is fixedly connected to a side of the swivel close to the bottom of the annular groove; a groove is provided on a side of the sealing block away from the swivel; the push plate is fixedly connected to the bottom of the groove by a connecting spring; the width of the annular groove decreases continuously as it approaches the air hole.

[0013] Preferably, a resistance rod is arranged between two adjacent sealing blocks; the resistance rod is fixedly connected to the rotating ring; a lubrication plate is inlaid on the inner wall of the annular groove; the lubrication plate, the push plate and the sealing block are all made of PTFE material.

[0014] Preferably, a purification cartridge is threadedly connected to the air inlet; the purification cartridge is filled with activated carbon particles.

[0015] Preferably, the upper end of the discharge port is rotatably connected with a bellows; and one end of the bellows away from the discharge port is threadedly connected to the powder discharge port.

[0016] Preferably, the upper end surface of the shell located at the bottom is provided with a circular groove connected to the annular groove; the lower end surface of the shell located above the circular groove is provided with a connecting groove connected to the air holes on its surface; the connecting groove cooperates with the circular groove.

[0017] The beneficial effects of the present invention are as follows:

[0018] The present invention arranges a grinding roller in a shell so that the grinding roller can directly dry and crush the screened sodium heparin block, thereby eliminating the need to transport the screened sodium heparin block. The grinding roller is located inside the shell, thereby reducing the contact between the sodium heparin block and external dust, preventing the sodium heparin powder from being contaminated, and improving the purity and quality of the sodium heparin.

[0019] The present invention embeds a lubricating plate on the inner wall of the annular groove so that the lubricating plate is in sliding contact with the sealing plate and the push plate. Since the lubricating plate, the push plate and the sealing block are all made of PTFE material, the lubricating plate, the push plate and the sealing block have the advantages of smooth surface and low friction coefficient, thereby reducing the friction loss of the push plate and the sealing block, and improving the sealing effect and service life of the push plate and the sealing block. In addition, by reducing the friction between the lubricating plate, the push plate and the sealing block, the resistance to the rotation of the mounting frame caused by the friction force can be reduced, so that when the mounting frame drives the push plate at the same rotation speed, the driving load of the driving motor is reduced, thereby reducing the power consumption of the driving motor and saving the consumption of electric energy, so that the actual application effect of the present invention is effectively improved. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] The present invention is further described below in conjunction with the accompanying drawings and implementation modes.

[0021] Figure 1 is a stereogram of the present invention;

[0022] Figure 2 It is a schematic diagram of the structure of the present invention;

[0023] Figure 3 yes Figure 2 The enlarged view of point A in the middle;

[0024] Figure 4 yes Figure 2 The enlarged view of point B in the middle;

[0025] Figure 5 is a schematic diagram of the structure of the annular plate used in the present invention;

[0026] Figure 6 yes Figure 5 Enlarged view of point C in the middle;

[0027] In the figure: 1, machine body; 11, oscillation motor; 12, shell; 121, filter plate; 122, guide plate; 123, feed port; 124, block outlet; 125, powder outlet; 126, crushing port; 127, discharge port; 13, grinding roller; 131, mounting frame; 132, shovel plate; 14, mounting plate; 141, turbine; 142, worm; 143, drive motor; 15, annular plate; 151, annular groove; 152, air hole; 153, push plate; 154, swivel; 155, sealing block; 156, groove; 157, connecting spring; 158, resistor rod; 159, lubrication plate; 16, air inlet; 161, purification cylinder; 17, bellows; 18, circular groove; 19, connecting groove. DETAILED DESCRIPTION

[0028] In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further explained below in conjunction with specific implementation methods.

[0029] like Figures 1 to 6 As shown, the impurity removal device of crude heparin sodium described in the present invention comprises:

[0030] A machine body 1, wherein an oscillation motor 11 is installed at the upper end of the machine body 1; a shell 12 is arranged above the machine body 1; the machine body 1 and the shell 12 are fixedly connected by an oscillation spring; the number of the shells 12 is three; the three shells 12 are distributed up and down; two adjacent shells 12 are rotatably connected; a filter plate 121 is arranged between the two upper shells 12; the filter plate 121 is fixedly connected to the shell 12; a guide plate 122 is fixedly connected to the upper end of the filter plate 121; a feed port 123, a block outlet 124, a powder outlet 125, a crushing port 126 and a discharge port 127 are sequentially provided on the surface of the shell 12 from top to bottom;

[0031] The grinding roller 13 is provided with a mounting plate 14 inside the shell 12 located at the bottom; the mounting plate 14 is fixedly connected to the shell 12; a turbine 141 is rotatably connected to the upper end of the mounting plate 14; a worm 142 meshing with the turbine 141 is provided on one side of the turbine 141; the worm 142 is rotatably connected to the shell 12; a driving motor 143 is installed on the outer wall of the shell 12; the driving motor 143 is used to drive the worm 142 to rotate; a mounting frame 131 fixedly connected to the turbine 141 is provided at the lower end of the mounting plate 14; the grinding roller 13 is rotatably connected to the lower end of the mounting frame 131.

[0032] As an embodiment of the present invention, an annular plate 15 is arranged below the mounting plate 14; the annular plate 15 is fixedly connected to the shell 12; a shovel plate 132 is arranged between the annular plate 15 and the mounting frame 131; the shovel plate 132 is fixedly connected to the mounting frame 131; the shovel plate 132 is arranged at an angle.

[0033] As an embodiment of the present invention, an annular groove 151 is provided inside the annular plate 15; an air inlet 16 connected to the annular groove 151 is provided on the outer wall of the shell 12; an air hole 152 is provided on the inner wall of the shell 12; the air hole 152 is connected to the annular groove 151; and a blowing unit is installed in the annular groove 151.

[0034] As an embodiment of the present invention, the blowing unit includes a push plate 153; a swivel 154 is rotatably connected in the annular groove 151; the swivel 154 is fixedly connected to the shovel plate 132; a sealing block 155 is fixedly connected to a side of the swivel 154 close to the bottom of the annular groove 151; a groove 156 is provided on a side of the sealing block 155 away from the swivel 154; the push plate 153 is fixedly connected to the bottom of the groove 156 by a connecting spring 157; the width of the annular groove 151 continuously decreases as it approaches the air hole 152.

[0035] As an embodiment of the present invention, a resistor rod 158 is provided between two adjacent sealing blocks 155; the resistor rod 158 is fixedly connected to the rotating ring 154; a lubricating plate 159 is inlaid on the inner wall of the annular groove 151; the lubricating plate 159, the push plate 153 and the sealing block 155 are all made of PTFE material;

[0036] During operation, in the prior art, a rotary vibrating screen is often used to screen the damp sodium heparin powder, and the screened sodium heparin block is often transported to a drying device for drying, and then the dried sodium heparin block is transported to a crushing device to crush the sodium heparin block into powder. In the process of transporting the screened sodium heparin block to the drying device and the crushing device, impurities such as dust from the outside will inevitably come into contact with the sodium heparin block, especially for the crushing device; dust from the outside is more likely to mix with the crushed sodium heparin powder, thereby causing the sodium heparin powder to be contaminated, thereby affecting the purity and quality of the sodium heparin;

[0037] In this regard, by arranging a grinding roller 13 in the housing 12, the grinding roller 13 can directly dry and crush the screened sodium heparin block, so that the screened sodium heparin block does not need to be transported, and the grinding roller 13 is located inside the housing 12, thereby reducing the contact between the sodium heparin block and the external dust, preventing the sodium heparin powder from being contaminated, so that the purity and quality of the sodium heparin are improved;

[0038] Before the present invention is used, the feed port 123 needs to be connected to an external feeding device, and the block outlet 124 and the crushing port 126 need to be connected through a discharge pipe; the feeding device is controlled to transport the damp heparin sodium powder from the feed port 123 to the interior of the uppermost shell 12, and the damp heparin sodium powder falls on the uppermost filter plate 121; then the oscillation motor 11 is controlled to operate, so that the oscillation motor 11 generates an oscillating force on the shell 12, so that the shell 12 drives the uppermost filter plate 121 oscillates the sodium heparin powder at the upper end, so that the powdered sodium heparin can pass through the mesh of the filter plate 121 and fall to the bottom of the filter plate 121 below; while the block sodium heparin blocked by the filter plate 121 is transported to the block outlet 124 along the guide plate 122, so that the block sodium heparin falling out of the block outlet 124 can enter the crushing port 126 through the discharge pipe, and enter the mounting plate 14 and the bottom of the lower shell 12 from the crushing port 126; control the drive motor 14 3 operates, so that the driving motor 143 can drive the worm 142 to drive the turbine 141 to rotate, so that the turbine 141 can drive the mounting frame 131 at the lower end to rotate synchronously, so that the mounting frame 131 drives the grinding roller 13 to rotate; because the grinding roller 13 is in rolling contact with the annular plate 15, when the block heparin sodium falls to the bottom of the housing 12 through the crushing opening 126, the grinding roller 13 will cooperate with the annular plate 15 to squeeze and break the block heparin sodium; and the setting of the shovel plate 132, The shovel plate 132 is capable of pushing the sodium heparin blocks that have fallen to the bottom of the housing 12 to rotate in a circle, so that the sodium heparin blocks that rotate in a circle are moved toward the annular plate 15 under the action of centrifugal force; and the shovel plate 132 is inclined, so that the sodium heparin blocks accumulated on one end of the shovel plate 132 close to the annular plate 15 will pass over the inclined surface of the shovel plate 132 to the grinding roller 13 for crushing, thereby increasing the contact area between the sodium heparin blocks and the grinding roller 13, thereby helping to improve the grinding effect;

[0039] Since the damp block of sodium heparin contains water, when the block of sodium heparin is crushed, the crushed sodium heparin powder still has a certain humidity inside. In this regard, the present invention is provided with an annular groove 151. When the mounting frame 131 drives the shovel plate 132 to rotate, the shovel plate 132 will drive the rotating ring 154 to rotate in the notch of the annular groove 151, so that the rotating ring 154 can drive the sealing block 155 and the push plate 153 connected thereto to rotate synchronously. Because the width of the annular groove 151 near the air hole 152 is narrower, and the width of the annular groove 151 near the air inlet 16 is wider, when the rotating ring 154 drives the sealing block 155 to rotate from the air inlet 16 to the air hole 152, the push plate 153 is away from the sealing block 15 5 is in sliding sealing contact with the wall of the annular groove 151; and in the process of rotating toward the air hole 152, the width of the annular groove 151 is continuously narrowed, so the push plate 153 is blocked by the wall of the annular groove 151 and squeezes the connecting spring 157 into the groove 156, and at this time the air between the two push plates 153 is compressed; when the push plate 153 rotates and passes over the air hole 152, the air hole 152 is located between the two push plates 153, so that the compressed gas between the two push plates 153 enters the air hole 152, and then the push plate 153 rotates in the direction close to the air inlet 16, and at this time the width of the annular groove 151 is increased, so that the push plate 153 in the groove 156 is pushed by the restoring force of the connecting spring 157. The groove 156 is extended downwardly from the two push plates 153, and the space between the two push plates 153 is increased, thereby reducing the gas pressure between the two push plates 153. When the push plate 153 passes over the air inlet 16, the external gas will enter between the two push plates 153 through the air inlet 16. Since the resistor rod 158 is located between the two push plates 153, the operation of the resistor rod 158 is controlled so that the resistor rod 158 is energized and generates heat. As the rotating ring 154 rotates, the resistor rod 158 rotates synchronously with the rotating ring 154, so that the resistor rod 158 can heat the gas between the two push plates 153, so that the heated gas can be sprayed into the housing 12 through the air hole 152. Since the air hole 152 is arranged obliquely, the air hole 152 The hot air ejected from 152 can be sprayed obliquely toward the block sodium heparin falling into the housing 12, so that the moisture in the block sodium heparin is volatilized by heat; thereby, the block sodium heparin is dried to reduce the humidity inside the crushed sodium heparin powder; the quality of the sodium heparin powder is improved, and the sodium heparin powder is prevented from agglomerating again; a filter plate 121 is provided at the lower end of the mounting plate 14, so that the crushed sodium heparin powder can be discharged from the discharge port 127 through the filter plate 121, while the uncrushed block sodium heparin is blocked by the filter plate 121 and continues to be ground in the housing 12; the sodium heparin powder discharged from the discharge port 127 and the powder discharge port 125 can be collected by the user using a collection bag;

[0040] By embedding a lubricating plate 159 on the inner wall of the annular groove 151, the lubricating plate 159 is in sliding contact with the sealing plate and the push plate 153; since the lubricating plate 159, the push plate 153 and the sealing block 155 are all made of PTFE material, the lubricating plate 159, the push plate 153 and the sealing block 155 have the advantages of smooth surface and low friction coefficient, thereby reducing the friction loss of the push plate 153 and the sealing block 155, and improving the sealing effect and service life of the push plate 153 and the sealing block 155; in addition, by reducing the friction between the lubricating plate 159 and the push plate 153 and the sealing block 155, the resistance to the rotation of the mounting frame 131 caused by the friction force can be reduced, so that the mounting frame 131 drives the push plate 153 under the condition of the same rotation speed, and the driving load of the driving motor 143 is reduced, thereby reducing the power consumption of the driving motor 143 and saving the consumption of electric energy; so that the actual application effect of the present invention is effectively improved.

[0041] As an embodiment of the present invention, the air inlet 16 is internally threadedly connected with a purification cartridge 161 ; the purification cartridge 161 is filled with activated carbon particles.

[0042] As an embodiment of the present invention, the upper end of the discharge port 127 is rotatably connected with a bellows 17 ; one end of the bellows 17 away from the discharge port 127 is threadedly connected to the powder discharge port 125 .

[0043] As an embodiment of the present invention, the upper end surface of the shell 12 located at the bottom is provided with a circular groove 18 connected to the annular groove 151; the lower end surface of the shell 12 located above the circular groove 18 is provided with a connecting groove 19 connected to the air hole 152 on its surface; the connecting groove 19 cooperates with the circular groove 18;

[0044] During operation, the setting of the air inlet 16 will cause dust in the outside air to enter the interior of the housing 12 through the air inlet 16, thereby contaminating the bulk heparin sodium in the housing 12. To this end, the present invention sets a purification cartridge 161. When in use, the user puts a filter bag containing activated carbon particles into the purification cartridge 161, and then threading the purification cartridge 161 into the air inlet 16, so that the purification cartridge 161 can purify the outside air entering the air inlet 16; dust and other harmful substances in the air can be adsorbed by the activated carbon, so that the outside air enters the annular groove 151 through the air inlet 16 after being purified by the activated carbon, thereby preventing dust in the outside air from entering the housing 12 through the annular groove 151, thereby preventing the housing 12 from being contaminated. The sodium heparin in the body 12 is contaminated, so that the quality of the sodium heparin is improved; by setting the bellows 17, the bellows 17 can connect the discharge port 127 with the powder discharge port 125, so that it is convenient for the user to collect the sodium heparin powder discharged from the powder discharge port 125 and the discharge port 127 together; because in the initial state, the powder discharge port 125 and the discharge port 127 are not aligned up and down, and the connecting groove 19 and the circular groove 18 are not aligned, at this time the user only needs to rotate the shell 12 with the powder discharge port 125, so that the powder discharge port 125 and the discharge port 127 are parallel to each other, and then stretch the bellows 17, so that the end of the bellows 17 away from the discharge port 127 contacts the powder discharge port 125, and as the bellows 17 is rotated, the bellows 1 7 can be threadedly connected in the powder discharge port 125; when the powder discharge port 125 is parallel to the discharge port 127, the connecting groove 19 is opposite to the circular groove 18; because the circular groove 18 is connected to the annular groove 151, part of the gas in the annular groove 151 is discharged from the air hole 152 on the surface of the shell 12 where it is located, and the other part of the gas enters the connecting groove 19 opposite to it through the circular groove 18. Since the connecting groove 19 is connected to the air hole 152 of the shell 12 with the powder discharge port 125, the gas entering the connecting groove 19 can be discharged from the air hole 152 on the surface of the shell 12 with the powder discharge port 125, so that the heparin sodium powder sieved from the upper filter plate 121 can be dried by the blowing of hot air, thereby ensuring that the heparin sodium powder The dryness of the powder is improved to improve the quality of the sodium heparin powder, thereby preventing the sodium heparin powder from agglomerating again; and by setting the air hole 152 to be inclined downward, the hot air flow ejected from the air hole 152 is inclined downward, so that the hot air flow inclined downward can blow the sodium heparin powder in the shell 12 to be discharged from the powder discharge port 125 and the discharge port 127, which greatly improves the discharge speed of the sodium heparin powder in the shell 12. If the air hole 152 is inclined upward, the air flow will cause the sodium heparin powder to be lifted up, which will not only affect the normal screening of the sodium heparin powder by the filter plate 121, but also cause the sodium heparin powder to adhere to the inner surface of the shell 12, resulting in waste of sodium heparin powder, and also cause the sodium heparin powder to spread in the shell 12, thereby increasing the risk of fire and explosion;In this regard, the present invention can prevent the sodium heparin powder from being lifted up in the housing 12 by setting the air hole 152 to be inclined downward, which not only avoids the risk of fire and explosion, but also facilitates the collection of the sodium heparin powder and reduces the waste of the sodium heparin powder, so that the practical application effect of the present invention is effectively improved. ;

[0045] In the description of the present invention, it should be noted that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like indicate directions or positional relationships based on the attached Figure 1 The orientation or positional relationship shown is only for the convenience of describing the present invention and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operate in a specific orientation. Therefore, it cannot be understood as limiting the scope of protection of the present invention. In addition, the terms "first", "second", "third", etc. are only used to distinguish the description and cannot be understood as indicating or implying relative importance.

[0046] The above shows and describes the basic principles, main features and advantages of the present invention. It should be understood by those skilled in the art that the present invention is not limited to the above embodiments. The above embodiments and descriptions are only for explaining the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which fall within the scope of the present invention. The scope of protection of the present invention is defined by the attached claims and their equivalents.

Claims

1. A crude heparin sodium impurity removal device, characterized in that: include: A machine body (1), wherein an oscillation motor (11) is installed at the upper end of the machine body (1); a shell (12) is arranged above the machine body (1); the machine body (1) and the shell (12) are fixedly connected via an oscillation spring; the number of the shells (12) is three; the three shells (12) are distributed up and down; two adjacent shells (12) are rotatably connected; a filter plate (121) is arranged between the two upper shells (12); the filter plate (121) is fixedly connected to the shell (12); a guide plate (122) is fixedly connected to the upper end of the filter plate (121); a feed port (123), a block discharge port (124), a powder discharge port (125), a crushing port (126) and a discharge port (127) are sequentially provided on the surface of the shell (12) from top to bottom; A grinding roller (13), wherein the grinding roller (13) is located inside a shell (12); a mounting plate (14) is provided inside the shell (12) at the bottom; the mounting plate (14) is fixedly connected to the shell (12); a turbine (141) is rotatably connected to the upper end of the mounting plate (14); a worm (142) meshing with the turbine (141) is provided on one side of the turbine (141); the worm (142) is rotatably connected to the shell (12); a driving motor (143) is installed on the outer wall of the shell (12); the driving motor (143) is used to drive the worm (142) to rotate; a mounting frame (131) fixedly connected to the turbine (141) is provided at the lower end of the mounting plate (14); and the grinding roller (13) is rotatably connected to the lower end of the mounting frame (131).

2. The impurity removal device for crude heparin sodium according to claim 1, characterized in that: An annular plate (15) is arranged below the mounting plate (14); the annular plate (15) is fixedly connected to the housing (12); a shovel plate (132) is arranged between the annular plate (15) and the mounting frame (131); the shovel plate (132) is fixedly connected to the mounting frame (131); and the shovel plate (132) is arranged at an angle.

3. The impurity removal device for crude heparin sodium according to claim 2, characterized in that: An annular groove (151) is provided inside the annular plate (15); an air inlet (16) connected to the annular groove (151) is provided on the outer wall of the shell (12); an air hole (152) is provided on the inner wall of the shell (12); the air hole (152) is connected to the annular groove (151); and an air blowing unit is installed in the annular groove (151).

4. The impurity removal device for crude heparin sodium according to claim 3, characterized in that: The blowing unit comprises a push plate (153); a rotating ring (154) is rotatably connected in the annular groove (151); the rotating ring (154) is fixedly connected to the shovel plate (132); a sealing block (155) is fixedly connected to a side of the rotating ring (154) close to the bottom of the annular groove (151); a groove (156) is provided on a side of the sealing block (155) away from the rotating ring (154); the push plate (153) is fixedly connected to the bottom of the groove (156) via a connecting spring (157); the width of the annular groove (151) decreases as it approaches the air hole (152).

5. The impurity removal device for crude heparin sodium according to claim 4, characterized in that: A resistance rod (158) is arranged between two adjacent sealing blocks (155); the resistance rod (158) is fixedly connected to the rotating ring (154); a lubricating plate (159) is inlaid on the inner wall of the annular groove (151); the lubricating plate (159), the push plate (153) and the sealing block (155) are all made of PTFE material.

6. The impurity removal device for crude heparin sodium according to claim 5, characterized in that: The air inlet (16) is internally threadedly connected to a purification cartridge (161); the purification cartridge (161) is filled with activated carbon particles.

7. The impurity removal device for crude heparin sodium according to claim 6, characterized in that: The upper end of the discharge port (127) is rotatably connected to a bellows (17); one end of the bellows (17) away from the discharge port (127) is threadedly connected to the powder discharge port (125).

8. The impurity removal device for crude heparin sodium according to claim 7, characterized in that: The upper end surface of the shell (12) located at the bottom is provided with a circular groove (18) connected to the annular groove (151); the lower end surface of the shell (12) located above the circular groove (18) is provided with a connecting groove (19) connected to the air hole (152) on its surface; the connecting groove (19) matches the circular groove (18).

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