Natural product synergistic extraction and purification control system

Through the natural product collaborative extraction and purification control system, the extraction and purification process is adjusted in real time using data acquisition and analysis models, the problem of insufficient efficiency and purity in the existing technology is solved, efficient and automated extraction and purification are achieved, and energy consumption is reduced and cost.

CN119139744APending Publication Date: 2024-12-17SUZHOU KEMIKEKU FOOD CO LTD
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Patent Information

Application Number
CN202411260204.9
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-09-10
Publication Date
2024-12-17

AI Technical Summary

Technical Problem

The existing natural product extraction and purification methods cannot ensure the extraction and purification efficiency and quality while controlling costs, and the degree of intelligent analysis of process parameters is insufficient.

Method used

A natural product collaborative extraction and purification control system was designed, including an extraction device, purification device, data acquisition unit, data processing unit and control adjustment unit. By collecting and analyzing technical parameters, an extraction and purification impact analysis model is constructed, and extraction is adjusted in real time. and purification process to improve efficiency and purity.

Benefits of technology

It improves extraction efficiency and purity, realizes continuous and automated extraction and purification processes, reduces energy consumption and labor costs, and improves the stability and operation convenience of the system.

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Abstract

The invention discloses a natural product synergistic extraction and purification control system, which adopts a data acquisition unit to acquire technical parameters of an extraction device and a purification device, adopts a data processing unit to obtain parameter influence values for extraction and purification processes, and controls an adjustment unit to adjust the extraction and purification processes respectively according to the corresponding influence values. The extraction efficiency and the purity are improved; the integrated design is adopted, and an extraction device and a purification device are integrated in one system, so that the continuous and automatic extraction and purification process is realized, and the energy consumption and the labor cost are reduced; an advanced control system is arranged, so that the whole extraction and purification process is monitored and managed in real time, and the stability and the operation convenience of the system are improved.
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Description

Technical Field

[0001] The invention relates to the technical field of raw material extraction and purification, and in particular to a natural product collaborative extraction and purification control system. Background Art

[0002] The extraction and purification of natural products is a key step in the pharmaceutical, food and chemical industries, and plays a vital role in drug development, health care product production and fine chemical product manufacturing. Traditional extraction and purification methods usually rely on manual operation, empirical control and simple mechanical equipment. These methods often have some problems, such as low extraction efficiency, serious loss of effective ingredients, low purity and high energy consumption, which makes it difficult to achieve large-scale production. The operation process is not easy to control and has a certain negative impact on the environment.

[0003] In order to overcome the above problems, in recent years, researchers have been constantly exploring new technologies and equipment to improve the extraction and purification efficiency of natural products, reduce energy consumption, and realize the automation and intelligence of the operation process. For example, the use of ultrasonic assisted extraction technology, supercritical fluid extraction technology, membrane separation technology, chromatographic separation technology, etc., these technologies have indeed improved the extraction efficiency and purity in some aspects, but they cannot guarantee the efficiency and quality of extraction and purification while controlling costs, and the degree of intelligent analysis of process parameters is insufficient. Summary of the invention

[0004] The purpose of this section is to summarize some aspects of embodiments of the present invention and briefly introduce some preferred embodiments. Some simplifications or omissions may be made in this section and the specification abstract and the invention title of this application to avoid blurring the purpose of this section, the specification abstract and the invention title, and such simplifications or omissions cannot be used to limit the scope of the present invention.

[0005] In view of the problems existing in the above-mentioned existing natural product extraction and purification methods, the present invention is proposed.

[0006] Therefore, the technical problem solved by the present invention is to solve the problem that the existing natural product extraction and purification methods cannot well guarantee the efficiency and quality of extraction and purification while controlling costs, and the degree of intelligent analysis of process parameters is insufficient.

[0007] To solve the above technical problems, the present invention provides the following technical solutions: a natural product collaborative extraction and purification control system, comprising the following components: an extraction device, used to extract natural products from raw materials and obtain an extract containing natural products; a purification device, used to purify the extracted extract; a data acquisition unit, respectively configured on the extraction device and the purification device, respectively collecting technical parameters of the extraction device and the purification device; a data processing unit, wirelessly connected to the data acquisition unit, obtaining corresponding technical parameters, constructing an extraction impact analysis model and a purification impact analysis model, and respectively obtaining extraction impact values ​​and purification impact values; a control and adjustment unit, wirelessly connected to the data processing unit, adjusting the extraction process according to the extraction impact value obtained by the data processing unit, and adjusting the purification process according to the purification impact value obtained by the data processing unit.

[0008] As a preferred solution of the natural product collaborative extraction and purification control system described in the present invention, the extraction device includes an extraction tank, an agitator, a heater and a filter; wherein the extraction tank is used to contain raw materials and extraction solvents, the agitator is used to stir the raw materials and the extraction solvents, the heater is used to provide the heat required for the extraction process, and the filter is used to separate the extract and the residue.

[0009] As a preferred solution of the natural product synergistic extraction and purification control system described in the present invention, the purification device includes a purification tank, a purification agitator, a purification heater and a purification filter; wherein the purification tank is used to contain the extraction liquid and the purification solvent, the purification agitator is used to stir the extraction liquid and the purification solvent, the purification heater is used to provide the heat required for the purification process, and the purification filter is used to separate the purification product and the waste liquid.

[0010] As a preferred solution of the natural product collaborative extraction and purification control system described in the present invention, the technical parameters of the extraction device collected by the data acquisition unit specifically include: the temperature inside the extraction device, the pressure inside the extraction device, the pH value inside the extraction device, the concentration of the extraction solvent configured in the extraction device, and the flow rate of the extraction solvent configured in the extraction device; the technical parameters of the purification device collected by the data acquisition unit specifically include: the temperature inside the purification device, the pressure inside the purification device, the pH value inside the purification device, the concentration of the purification solvent configured in the purification device, and the flow rate of the purification solvent configured in the purification device.

[0011] As a preferred solution of the natural product collaborative extraction and purification control system of the present invention, the constructed extraction impact analysis model is specifically:

[0012]

[0013] Wherein, δ is the extraction influence value; α is the temperature in the extraction device, ℃; β is the pressure in the extraction device, Pa; γ is the pH value in the extraction device; ω is the concentration of the extraction solvent configured in the extraction device, mol / L; v is the flow rate of the extraction solvent configured in the extraction device, cm / s; 1.33, 1.065, 2.40 and 2.55 are all adjustment constants; dx is an integral operation.

[0014] As a preferred solution of the natural product collaborative extraction and purification control system of the present invention, the purification impact analysis model constructed is specifically:

[0015]

[0016] Wherein, η is the purification influence value; κ is the temperature in the purification device, ℃; θ is the pressure in the purification device, Pa; λ is the pH value in the purification device; ε is the concentration of the purification solvent configured in the purification device, mol / L; τ is the flow rate of the purification solvent configured in the purification device, cm / s; 2.06, 1.11, 1.984 and 2.32 are all adjustment constants; dx is an integral operation.

[0017] As a preferred solution of the natural product synergistic extraction and purification control system described in the present invention, wherein: adjusting the extraction process according to the extraction influence value obtained by the data processing unit specifically includes the following steps: S1: constructing the extraction influence analysis model, inputting the currently monitored and recorded extraction parameters, and outputting the current extraction influence value in real time; S2: within the rated time, using the current extraction parameters to perform extraction, and determining the extraction rate corresponding to the current extraction influence value; S3: correcting the extraction parameters in different extraction time periods, and obtaining the corrected extraction influence value; S4: correcting the extraction parameters multiple times in different extraction time periods, and obtaining multiple extraction influence values ​​after multiple corrections in each extraction time period; S5: constructing a difference detection model, arbitrarily selecting an extraction influence value in different extraction time periods as input, and outputting a difference difference value; S6: obtaining the corrected extraction parameters corresponding to different extraction time periods whose difference difference values ​​meet the requirements.

[0018] As a preferred solution of the natural product collaborative extraction and purification control system described in the present invention, wherein: adjusting the purification process according to the purification influence value obtained by the data processing unit specifically includes the following steps: S1: constructing the purification influence analysis model, inputting the purification parameters currently monitored and recorded, and outputting the current purification influence value in real time; S2: within the rated time, using the current purification parameters for purification, and determining the purification rate corresponding to the current purification influence value; S3: correcting the purification parameters in different purification time periods, and obtaining the corrected purification influence value; S4: correcting the purification parameters multiple times in different purification time periods, and obtaining multiple purification influence values ​​after multiple corrections in each purification time period; S5: constructing a purification difference detection model, arbitrarily selecting a purification influence value input in different purification time periods, and outputting the purification difference difference value; S6: obtaining the corrected purification parameters corresponding to different purification time periods whose purification difference values ​​meet the requirements.

[0019] As a preferred solution of the natural product collaborative extraction and purification control system of the present invention, the constructed difference detection model is specifically:

[0020]

[0021] Where A is the difference difference value; δ1 is the extraction influence value selected in the first extraction time period; δ2 is the extraction influence value selected in the second extraction time period; δ n is the extraction impact value selected in the nth extraction time period; n is the number of extraction time periods; δ max is the maximum value among the selected extraction influence values; δ min is the minimum value among the selected extraction influence values; 1.033 is the adjustment constant; dx is the integral operation.

[0022] As a preferred solution of the natural product collaborative extraction and purification control system of the present invention, the constructed purification difference detection model is specifically:

[0023]

[0024] Wherein, B is the purification difference difference value; η1 is the purification influence value selected in the first purification time period; η2 is the purification influence value selected in the second purification time period; η m is the purification impact value selected in the mth purification time period; m is the number of divisions of the purification time period; η max is the maximum value among the selected purification impact values; η min is the minimum value among the selected purification influence values; 1.033 is the adjustment constant; dx is the integral operation.

[0025] The present invention provides a natural product collaborative extraction and purification control system, which has the following beneficial effects:

[0026] 1. The data acquisition unit is used to collect the technical parameters of the extraction device and the purification device. The data processing unit obtains the parameter influence values ​​of the extraction and purification processes. The control and adjustment unit adjusts the extraction and purification processes according to the corresponding influence values ​​to improve the extraction efficiency and purity.

[0027] 2. Adopt integrated design to integrate extraction and purification devices into one system, realize continuous and automated extraction and purification process, and reduce energy consumption and labor costs.

[0028] 3. Equipped with advanced control system to realize real-time monitoring and management of the entire extraction and purification process, and improve the stability of the system and the convenience of operation. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the following briefly introduces the drawings required for describing the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative labor. Among them:

[0030] Figure 1 This is an overall system diagram of the natural product collaborative extraction and purification control system provided by the present invention.

[0031] Figure 2 A flow chart of a method for adjusting an extraction process according to an extraction influence value obtained by a data processing unit provided by the present invention.

[0032] Figure 3 A flow chart of a method for adjusting a purification process according to a purification influence value obtained by a data processing unit provided by the present invention. DETAILED DESCRIPTION

[0033] In order to make the above-mentioned purposes, features and advantages of the present invention more obvious and easy to understand, the specific implementation methods of the present invention are described in detail below in conjunction with the drawings of the specification. Obviously, the described embodiments are part of the embodiments of the present invention, but not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary persons in the art without creative work should fall within the scope of protection of the present invention.

[0034] In the field of natural product extraction and purification, ultrasound-assisted extraction technology, supercritical fluid extraction technology, membrane separation technology, chromatographic separation technology and other technologies have indeed improved the extraction efficiency and purity in some aspects, but they are unable to guarantee the efficiency and quality of extraction and purification while controlling costs, and the level of intelligent analysis of process parameters is insufficient.

[0035] Therefore, please refer to Figure 1 The present invention provides a natural product collaborative extraction and purification control system, comprising the following components:

[0036] An extraction device, used to extract natural products from raw materials to obtain an extract containing natural products;

[0037] A purification device, used for purifying the extracted liquid;

[0038] The data acquisition units are respectively arranged on the extraction device and the purification device to respectively collect technical parameters of the extraction device and the purification device;

[0039] The data processing unit is wirelessly connected to the data acquisition unit to obtain corresponding technical parameters, build an extraction impact analysis model and a purification impact analysis model, and obtain an extraction impact value and a purification impact value respectively;

[0040] The control and adjustment unit is wirelessly connected to the data processing unit, and adjusts the extraction process according to the extraction influence value obtained by the data processing unit, and adjusts the purification process according to the purification influence value obtained by the data processing unit.

[0041] Specifically, the extraction device includes an extraction tank, a stirrer, a heater and a filter; wherein the extraction tank is used to contain the raw material and the extraction solvent, the stirrer is used to stir the raw material and the extraction solvent, the heater is used to provide the heat required for the extraction process, and the filter is used to separate the extract and the residue. This is a direct application of existing mature technology and no redundant description is given here.

[0042] Specifically, the purification device includes a purification tank, a purification agitator, a purification heater and a purification filter; wherein the purification tank is used to contain the extract and the purification solvent, the purification agitator is used to stir the extract and the purification solvent, the purification heater is used to provide the heat required for the purification process, and the purification filter is used to separate the purification product and the waste liquid. This is a direct application of existing mature technology and no unnecessary details are given here.

[0043] Furthermore, the technical parameters of the extraction device collected by the data acquisition unit specifically include: the temperature inside the extraction device, the pressure inside the extraction device, the pH value inside the extraction device, the concentration of the extraction solvent configured in the extraction device, and the flow rate of the extraction solvent configured in the extraction device; the technical parameters of the purification device collected by the data acquisition unit specifically include: the temperature inside the purification device, the pressure inside the purification device, the pH value inside the purification device, the concentration of the purification solvent configured in the purification device, and the flow rate of the purification solvent configured in the purification device.

[0044] It should be noted that the sensor network specifically includes:

[0045] 1. Temperature sensor:

[0046] Type: Temperature is usually measured using a thermocouple or thermistor such as a platinum temperature sensor Pt100 or Pt1000.

[0047] Location: Temperature sensors should be deployed at key locations in the extraction or purification device, such as inside the extraction or purification tank or near the heating elements of the extraction or purification tank.

[0048] Technical details: The sensor should have high precision and fast response characteristics to ensure accurate capture of temperature changes during the extraction or purification process. The heat transfer medium between the sensor and the extraction or purification tank should have good thermal conductivity to reduce heat loss.

[0049] 2. Pressure sensor:

[0050] Type: Use pressure transmitters to measure pressure within extraction or purification units.

[0051] Location: Pressure sensors are typically mounted on the top or side of extraction or purification tanks, and near pumps and valves.

[0052] Technical details: The sensor should be strong and corrosion-resistant enough to withstand pressure fluctuations during extraction or purification. The output signal of the sensor should be compatible with the data acquisition system to accurately record pressure data.

[0053] 3. pH sensor:

[0054] Type: Use electrode-type pH sensors to measure the pH of extraction or purification solutions.

[0055] Location: The pH sensor should be placed inside the extraction or purification tank so that it is in direct contact with the extraction or purification solution.

[0056] Technical details: The sensor should have good stability and repeatability, as well as resistance to chemicals that may be present in the extraction or purification solution. The calibration and maintenance of the sensor should be easy to operate to ensure accurate pH measurement.

[0057] 4. Extraction or purification solvent concentration sensor:

[0058] Type: Use a spectrometer, turbidity meter, or chemical sensor to measure the concentration of extraction or purification solvents.

[0059] Location: The concentration sensor can be installed at or near the outlet of the extraction or purification tank.

[0060] Technical details: The sensor should be able to respond quickly and accurately measure changes in the concentration of the extraction or purification solvent. For the spectrometer, a wavelength range suitable for measuring the solvent concentration should be selected.

[0061] 5. Extraction or purification solvent flow sensor:

[0062] Type: Use a flow meter (such as an electromagnetic flow meter, ultrasonic flow meter, or impeller flow meter) to measure the flow rate of the extraction or purification solvent.

[0063] Location: The flow sensor should be installed in the flow path of the extraction or purification solvent, such as on the inlet and outlet pipes of the extraction or purification tank.

[0064] Technical details: The sensor should have high accuracy and stability and be able to adapt to the flow rate changes that may occur during the extraction or purification process. The sensor should be installed to ensure minimal disturbance to the fluid.

[0065] The real-time monitoring and recording of extraction or purification parameters by the sensor network are integrated and managed by a data acquisition and processing unit (DAS). The data acquisition system should have the following technical details:

[0066] Compatibility: Ensure that the interface between the sensor and the data acquisition system is compatible so that data can be transferred smoothly.

[0067] Communication interface: The acquisition system should have an interface for communicating with the superior control system or remote monitoring center, such as Ethernet, wireless network or serial communication port.

[0068] Storage and Reporting: The system should be able to store large amounts of data and generate reports.

[0069] Furthermore, the constructed extraction impact analysis model is specifically as follows:

[0070]

[0071] Wherein, δ is the extraction influence value; α is the temperature in the extraction device, ℃; β is the pressure in the extraction device, Pa; γ is the pH value in the extraction device; ω is the concentration of the extraction solvent configured in the extraction device, mol / L; v is the flow rate of the extraction solvent configured in the extraction device, cm / s; 1.33, 1.065, 2.40 and 2.55 are all adjustment constants; dx is the integral operation.

[0072] Furthermore, the constructed purification impact analysis model is specifically as follows:

[0073]

[0074] Wherein, η is the purification influence value; κ is the temperature in the purification device, ℃; θ is the pressure in the purification device, Pa; λ is the pH value in the purification device; ε is the concentration of the purification solvent configured in the purification device, mol / L; τ is the flow rate of the purification solvent configured in the purification device, cm / s; 2.06, 1.11, 1.984 and 2.32 are all adjustment constants; dx is the integral operation.

[0075] For further information, see Figure 2 , adjusting the extraction process according to the extraction influence value obtained by the data processing unit specifically includes the following steps:

[0076] S1: Construct an extraction impact analysis model, input the currently monitored and recorded extraction parameters, and output the current extraction impact value in real time;

[0077] S2: Within the rated time, the current extraction parameters are used to perform extraction and the extraction rate corresponding to the current extraction impact value is determined;

[0078] It should be noted that determining the extraction rate corresponding to the current extraction impact value is a direct application of existing mature technology and will not be elaborated here.

[0079] S3: Correcting the extraction parameters at different extraction time periods to obtain the corrected extraction impact value;

[0080] S4: Correcting the extraction parameters multiple times in different extraction time periods, and obtaining multiple extraction influence values ​​after multiple corrections in each extraction time period;

[0081] S5: construct a difference detection model, select any extraction influence value in different extraction time periods as input, and output the difference distinction value;

[0082] S6: Obtain corrected extraction parameters corresponding to different extraction time periods whose difference values ​​meet the requirements.

[0083] Specifically, the constructed difference detection model is as follows:

[0084]

[0085] Where A is the difference difference value; δ1 is the extraction influence value selected in the first extraction time period; δ2 is the extraction influence value selected in the second extraction time period; δ n is the extraction impact value selected in the nth extraction time period; n is the number of extraction time periods; δ max is the maximum value among the selected extraction influence values; δ min is the minimum value among the selected extraction influence values; 1.033 is the adjustment constant; dx is the integral operation.

[0086] Specifically, the rated time is defined as 5 to 10 minutes.

[0087] It should be noted that different extraction time periods are evenly divided in chronological order, and in order to ensure that at least one extraction rate can be calculated for each extraction time period, the division time of each extraction time period is not less than the rated time.

[0088] Specifically, when the difference difference value is less than or equal to 3.457, it is determined that the replaced current group extraction parameters meet the requirements.

[0089] It should be noted that there may be more than one set of extraction parameter groups that meet the requirements. You can select one set that meets the requirements, and the final total extraction results will not be much different.

[0090] Furthermore, adjusting the purification process according to the purification impact value obtained by the data processing unit specifically includes the following steps:

[0091] S1: Construct a purification impact analysis model, input the currently monitored and recorded purification parameters, and output the current purification impact value in real time;

[0092] S2: within the rated time, the current purification parameters are used for purification, and the purification rate corresponding to the current purification impact value is determined;

[0093] It should be noted that the determination of the purification rate corresponding to the current purification impact value is a direct application of existing mature technology and will not be elaborated here.

[0094] S3: Correcting purification parameters at different purification time periods to obtain corrected purification impact values;

[0095] S4: Correcting the purification parameters multiple times in different purification time periods, and obtaining multiple purification influence values ​​after multiple corrections in each purification time period;

[0096] S5: construct a purification difference detection model, select any one purification influence value in different purification time periods as input, and output the purification difference distinction value;

[0097] S6: Obtaining corrected purification parameters corresponding to different purification time periods whose purification difference values ​​meet the requirements.

[0098] Specifically, the constructed purification difference detection model is as follows:

[0099]

[0100] Wherein, B is the purification difference difference value; η1 is the purification influence value selected in the first purification time period; η2 is the purification influence value selected in the second purification time period; η m is the purification impact value selected in the mth purification time period; m is the number of divisions of the purification time period; η max is the maximum value among the selected purification impact values; η min is the minimum value among the selected purification influence values; 1.033 is the adjustment constant; dx is the integral operation.

[0101] Specifically, the rated time is defined as 5 to 10 minutes.

[0102] It should be noted that different purification time periods are evenly divided in chronological order, and in order to ensure that at least one purification rate can be calculated for each extraction time period, the division time of each purification time period is not less than the rated time.

[0103] Specifically, when the purification difference difference value is less than or equal to 2.631, it is determined that the replaced current group of purification parameters meets the requirements.

[0104] It should be additionally noted that there may be more than one set of purification parameter groups that meet the requirements. You can select one of the sets that meets the requirements, and the final overall extraction results will not differ much.

[0105] The present invention provides a natural product collaborative extraction and purification control system, which has the following beneficial effects:

[0106] 1. The data acquisition unit is used to collect the technical parameters of the extraction device and the purification device. The data processing unit obtains the parameter influence values ​​of the extraction and purification processes. The control and adjustment unit adjusts the extraction and purification processes according to the corresponding influence values ​​to improve the extraction efficiency and purity.

[0107] 2. Adopt integrated design to integrate extraction and purification devices into one system, realize continuous and automated extraction and purification process, and reduce energy consumption and labor costs.

[0108] 3. Equipped with advanced control system to realize real-time monitoring and management of the entire extraction and purification process, and improve the stability of the system and the convenience of operation.

[0109] It should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention rather than to limit it. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solutions of the present invention may be modified or replaced by equivalents without departing from the spirit and scope of the technical solutions of the present invention, which should all be included in the scope of the claims of the present invention.

Claims

1. A natural product collaborative extraction and purification control system, characterized in that: Includes the following components: An extraction device, used to extract natural products from raw materials to obtain an extract containing natural products; A purification device, used for purifying the extracted liquid; Data collection units are respectively arranged on the extraction device and the purification device to collect technical parameters of the extraction device and the purification device respectively; A data processing unit is wirelessly connected to the data acquisition unit to obtain corresponding technical parameters, construct an extraction impact analysis model and a purification impact analysis model, and obtain an extraction impact value and a purification impact value respectively; The control and adjustment unit is wirelessly connected to the data processing unit, and adjusts the extraction process according to the extraction influence value obtained by the data processing unit, and adjusts the purification process according to the purification influence value obtained by the data processing unit.

2. The natural product collaborative extraction and purification control system according to claim 1, characterized in that: The extraction device comprises an extraction tank, an agitator, a heater and a filter; wherein the extraction tank is used to contain raw materials and extraction solvent, the agitator is used to stir the raw materials and extraction solvent, the heater is used to provide heat required for the extraction process, and the filter is used to separate the extract and the residue.

3. The natural product collaborative extraction and purification control system according to claim 2, characterized in that: The purification device comprises a purification tank, a purification agitator, a purification heater and a purification filter; wherein the purification tank is used to contain the extract and the purification solvent, the purification agitator is used to stir the extract and the purification solvent, the purification heater is used to provide the heat required for the purification process, and the purification filter is used to separate the purification product and the waste liquid.

4. The natural product collaborative extraction and purification control system according to claim 3, characterized in that: The technical parameters of the extraction device collected by the data collection unit specifically include: the temperature inside the extraction device, the pressure inside the extraction device, the pH value inside the extraction device, the concentration of the extraction solvent configured in the extraction device, and the flow rate of the extraction solvent configured in the extraction device; the technical parameters of the purification device collected by the data collection unit specifically include: the temperature inside the purification device, the pressure inside the purification device, the pH value inside the purification device, the concentration of the purification solvent configured in the purification device, and the flow rate of the purification solvent configured in the purification device.

5. The natural product collaborative extraction and purification control system according to claim 4, characterized in that: The extraction impact analysis model constructed is specifically: Wherein, δ is the extraction influence value; α is the temperature in the extraction device, ℃; β is the pressure in the extraction device, Pa; γ is the pH value in the extraction device; ω is the concentration of the extraction solvent configured in the extraction device, mol / L; v is the flow rate of the extraction solvent configured in the extraction device, cm / s; 1.33, 1.065, 2.40 and 2.55 are all adjustment constants; dx is an integral operation.

6. The natural product collaborative extraction and purification control system according to claim 5, characterized in that: The purification impact analysis model constructed is specifically: Wherein, η is the purification influence value; κ is the temperature in the purification device, ℃; θ is the pressure in the purification device, Pa; λ is the pH value in the purification device; ε is the concentration of the purification solvent configured in the purification device, mol / L; τ is the flow rate of the purification solvent configured in the purification device, cm / s; 2.06, 1.11, 1.984 and 2.32 are all adjustment constants; dx is an integral operation.

7. The natural product collaborative extraction and purification control system according to claim 6, characterized in that: Adjusting the extraction process according to the extraction influence value obtained by the data processing unit specifically includes the following steps: S1: construct the extraction impact analysis model, input the currently monitored and recorded extraction parameters, and output the current extraction impact value in real time; S2: Within the rated time, the current extraction parameters are used to perform extraction and the extraction rate corresponding to the current extraction impact value is determined; S3: Correcting the extraction parameters at different extraction time periods to obtain the corrected extraction impact value; S4: Correcting the extraction parameters multiple times in different extraction time periods, and obtaining multiple extraction influence values ​​after multiple corrections in each extraction time period; S5: construct a difference detection model, select any extraction influence value in different extraction time periods as input, and output the difference distinction value; S6: Obtain corrected extraction parameters corresponding to different extraction time periods whose difference values ​​meet the requirements.

8. The natural product collaborative extraction and purification control system according to claim 7, characterized in that: Adjusting the purification process according to the purification influence value obtained by the data processing unit specifically includes the following steps: S1: construct the purification impact analysis model, input the currently monitored and recorded purification parameters, and output the current purification impact value in real time; S2: within the rated time, purify using the current purification parameters and determine the purification rate corresponding to the current purification impact value; S3: Correcting purification parameters at different purification time periods to obtain corrected purification impact values; S4: Correcting the purification parameters multiple times in different purification time periods, and obtaining multiple purification influence values ​​after multiple corrections in each purification time period; S5: construct a purification difference detection model, select any one purification influence value in different purification time periods as input, and output the purification difference distinction value; S6: Obtaining corrected purification parameters corresponding to different purification time periods whose purification difference values ​​meet the requirements.

9. The natural product collaborative extraction and purification control system according to claim 8, characterized in that: The difference detection model constructed is as follows: Where A is the difference difference value; δ1 is the extraction influence value selected in the first extraction time period; δ2 is the extraction influence value selected in the second extraction time period; δ n is the extraction impact value selected in the nth extraction time period; n is the number of extraction time periods; δ max is the maximum value among the selected extraction influence values; δ min is the minimum value among the selected extraction influence values; 1.033 is the adjustment constant; dx is the integral operation.

10. The natural product collaborative extraction and purification control system according to claim 9, characterized in that: The constructed purification difference detection model is as follows: Wherein, B is the purification difference difference value; η1 is the purification influence value selected in the first purification time period; η2 is the purification influence value selected in the second purification time period; η m is the purification impact value selected in the mth purification time period; m is the number of divisions of the purification time period; η max is the maximum value among the selected purification impact values; η min is the minimum value among the selected purification influence values; 1.033 is the adjustment constant; dx is the integral operation.

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