Automatic cooling device for heparin sodium production
By designing an automatic cooling device for sodium heparin production, the problem of dispersion of filtrate cooling and oil-slide removal steps is solved, rapid cooling of filtrate and automatic removal of oil-slide, and the efficiency and degree of automation of hepatic sodium extracting are improved.
Patent Information
- Application Number
- CN202411711692.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-27
- Publication Date
- 2025-02-28
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
During the existing production process of sodium heparin, the filtrate cooling and oil-slide removal steps are dispersed, with low efficiency and low automation, resulting in limited hepatic sodium extraction efficiency and high worker working intensity.
An automatic cooling device for the production of sodium heparin is designed, including a sliding operation table, a refrigerator, a scraper, a series shaft, a heat discharge and a fan. The motor and a refrigerator are controlled through the control panel to realize the automatic cooling of the filtrate and the automatic removal of oil slimming.
The device can speed up the cooling rate of the filtrate, automatically remove oil slimming, improve the efficiency of hepatic sodium extraction, enhance the degree of automation, and reduce the work intensity of workers.
Smart Images

Figure CN119533089A_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of heparin sodium production and processing equipment, in particular to an automatic cooling device for heparin sodium production. Background Art
[0002] Heparin sodium is an anticoagulant that can interfere with many aspects of the blood coagulation process and has an anticoagulant effect both in vivo and in vitro. The production of heparin sodium requires pig small intestine as raw material. After the raw material processing is completed, the filtrate needs to be heated and enzymatically hydrolyzed and cooled and adsorbed to ensure the smooth progress of subsequent processing.
[0003] Currently, the raw materials of hepatitis natriuretic peptide are cooled in a static manner after being heated and enzymatically hydrolyzed. This method is not only slow and inefficient, but also inconvenient for subsequent floating oil removal operations. In addition, the cooling and floating oil removal operations are divided into two steps, which are manually processed in sequence without being integrated. Therefore, the overall degree of automation is low, resulting in limited hepatitis natriuretic peptide extraction efficiency and high work intensity for workers. Summary of the invention
[0004] In view of the shortcomings of the prior art, the present invention provides an automatic cooling device for heparin sodium production, which solves the existing problems of relatively scattered filtrate cooling and floating oil removal steps and low heparin sodium extraction efficiency.
[0005] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: an automatic cooling device for producing sodium heparin, comprising a cooling pool, a control panel, and a pipe connection port, wherein the control panel is arranged on the outer end surface of the cooling pool, the pipe connection port is opened at the side end of the cooling pool, and a first motor is arranged at the side end of the cooling pool.
[0006] A sliding workbench is arranged on the outside of the cooling pool, a refrigerator is arranged on the upper end of the sliding workbench, a gas pipeline is arranged on the upper end of the refrigerator, a second motor is arranged on the same side of the upper end of the sliding workbench, a scraper is also arranged on the inside of the cooling pool, a series shaft is arranged on the inner wall of the cooling pool, and a fan is arranged on the upper end of the side wall of the cooling pool.
[0007] The serial shaft also includes a fixed disk and a heat sink. The fixed disk is fixedly connected to the outer end surface of the serial shaft, and the heat sink is fixedly connected to the side end of the fixed disk.
[0008] In some embodiments, two groups of fixed disks are provided, and five groups of heat sinks are provided, and the single body is a rectangular structure with multiple groups of grooves extending inwardly formed on the outer side, and the heat sink is fixedly connected between the two groups of fixed disks.
[0009] In some embodiments, the sliding workbench also includes an embedding groove, an oil scraping port, a limiting slide groove, a lateral limiting groove and a cavity. The embedding groove is opened on the inner side of the sliding workbench, the oil scraping port is opened on the inner side of the embedding groove, and the limiting slide groove is opened on the top of the sliding workbench.
[0010] In some embodiments, the lateral limit groove is formed on an end surface of the oil scraper port away from the first motor, the cavity is formed inside the sliding workbench, and the rear end is connected to the upper end.
[0011] In some of the embodiments, the embedding groove and the oil scraping port are connected front to back, and a side of the cavity facing the cooling pool is fixedly connected to an edge of the cooling pool.
[0012] In some embodiments, the scraper also includes a slider, a driving gear, a guide wheel and a rack. The slider is provided in two groups and is fixedly connected to the upper end of the scraper. The guide wheel is provided in four groups and is movably connected to the end surface of the scraper away from the first motor through an axis structure.
[0013] In some of the embodiments, the rack is fixedly connected to a side end surface away from the guide wheel and meshes with the tooth groove of the driving gear, and the guide wheel is embedded in the lateral limiting groove.
[0014] In some of the embodiments, the upper end of the sliding block passes through the upper end surface of the sliding workbench and establishes a sliding connection relationship with the limiting sliding groove.
[0015] In some of the embodiments, the end of the serial shaft facing the first motor passes through the inner wall of the cooling pool to establish a movable connection with the first motor, and a bearing structure is provided at the position where the serial shaft is connected to the cooling pool.
[0016] Compared with the prior art, the present invention provides an automatic cooling device for heparin sodium production:
[0017] An automatic cooling device for sodium heparin production is provided with a sliding workbench, a refrigerator, a scraper, a series connection shaft, a heat exhaust, an oil scraping port, and a driving gear and a rack. When the device is used, an operator controls a first motor, a second motor, a refrigerator, and a fan through a control panel, and introduces a filtrate after heated enzymolysis into a cooling pool through a pipeline connection port. The series connection shaft is driven to rotate by the first motor, and the series connection shaft drives a fixed disk and a peripheral heat exhaust to rotate. The heat exhaust continuously rotates in the filtrate, and heat exchange is completed while stirring the inside of the filtrate. At the same time, the fan continuously blows to the heat exhaust exposed on the surface of the filtrate, and the heat exhaust exposed on the surface of the filtrate is quickly dissipated, and the heat exhaust is immersed again in the slow rotation of the series connection shaft. The scraper is driven by the gear and the rack to move toward the surface of the filtrate. ...
[0018] The above settings and processes can make the device have the following beneficial effects:
[0019] Through the coordination of the serial shaft, heat sink and fan, the filtrate in the cooling pool can be cooled automatically, which can speed up the cooling process compared with traditional static cooling. Through the coordination of the sliding workbench, driving gear, scraper and oil scraper port, the floating oil on the surface of the filtrate can be automatically removed, thereby combining the floating oil removal operation with the filtrate cooling step, which not only greatly improves the extraction efficiency of hepatic natriuretic peptide, but also improves the degree of automation and reduces the workload of workers. BRIEF DESCRIPTION OF THE DRAWINGS
[0020] Figure 1 It is a schematic diagram of the overall structure of the present invention;
[0021] Figure 2 It is a schematic diagram of the top structure of the present invention;
[0022] Figure 3 This is a schematic diagram of the fan installation position structure of the present invention;
[0023] Figure 4 This is a schematic diagram of the installation position structure of the serially connected shaft and the scraper of the present invention;
[0024] Figure 5 This is a schematic diagram of the structure of the connection between the sliding workbench and the cooling pool of the present invention;
[0025] Figure 6 It is a schematic diagram of the overall structure of the scraper of the present invention;
[0026] Figure 7 It is a schematic diagram of the installation position structure of the serial shaft and the peripheral heat sink of the present invention.
[0027] In the figure: 1. Cooling tank; 2. Control panel; 3. Pipe connection port; 4. Sliding workbench; 401. Embedded groove; 402. Oil scraper port; 403. Limit slide groove; 404. Lateral limit groove; 405. Cavity; 5. First motor; 6. Refrigerator; 7. Gas pipeline; 8. Second motor; 9. Scraper; 901. Slider; 902. Drive gear; 903. Guide wheel; 904. Rack; 10. Serial shaft; 1001. Fixed plate; 1002. Heat dissipation; 11. Fan. DETAILED DESCRIPTION
[0028] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0029] In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "front end", "rear end", "two ends", "one end", "the other end" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first" and "second" are used for descriptive purposes only and cannot be understood as indicating or implying relative importance.
[0030] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "provided with", "connected", etc. should be understood in a broad sense. For example, "connected" can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.
[0031] In the present embodiment: an automatic cooling device for producing sodium heparin includes a cooling pool 1, a control panel 2, and a pipe connection port 3. The control panel 2 is arranged on the outer end face of the cooling pool 1, and the pipe connection port 3 is opened at the side end of the cooling pool 1. The pipe connection port 3 is connected to an external delivery pipeline. A first motor 5 is arranged at the side end of the cooling pool 1, and the first motor 5 drives the series shaft 10.
[0032] A sliding workbench 4 is arranged on the outside of the cooling pool 1, a refrigerator 6 is arranged on the upper end of the sliding workbench 4, a gas pipeline 7 is arranged on the upper end of the refrigerator 6, a second motor 8 is arranged on the same side of the upper end of the sliding workbench 4, a scraper 9 is also arranged on the inside of the cooling pool 1, a series shaft 10 is arranged on the inner wall of the cooling pool 1, and a fan 11 is arranged on the upper end of the side wall of the cooling pool 1.
[0033] The serial shaft 10 further includes a fixed disk 1001 and a heat sink 1002 . The fixed disk 1001 is fixedly connected to the outer end surface of the serial shaft 10 , and the heat sink 1002 is fixedly connected to the side end of the fixed disk 1001 .
[0034] In this embodiment, two groups of fixed disks 1001 are provided, and five groups of heat sinks 1002 are provided, and the single body is in a rectangular structure, and multiple groups of grooves extending inward are provided on the outer side thereof, and the heat sink 1002 is fixedly connected between the two groups of fixed disks 1001; the sliding workbench 4 also includes an embedding groove 401, an oil scraping port 402, a limiting slide groove 403, a lateral limiting groove 404 and a cavity 405, the embedding groove 401 is provided on the inner side of the sliding workbench 4, the oil scraping port 402 is provided on the inner side of the embedding groove 401, and the limiting slide groove 403 is provided on the top of the sliding workbench 4;
[0035] Specifically, Figure 1 Figure 5 as well as Figure 7 As shown, the inward grooves formed on the outer side of the heat row 1002 can increase the heat exchange area between the heat row 1002 and the air when the fan 11 is operating, thereby improving the heat exchange efficiency and achieving rapid cooling.
[0036] In this embodiment, the lateral limit groove 404 is opened on the end surface of the oil scraping port 402 away from the first motor 5, and the cavity 405 is opened inside the sliding workbench 4, and the rear end is connected with the upper end; the embedded groove 401 is connected with the oil scraping port 402 front and back, and the cavity 405 is fixedly connected to the edge of the cooling pool 1 on the side thereof; the scraper 9 also includes a slider 901, a driving gear 902, a guide wheel 903 and a rack 904, the slider 901 is provided with two groups and is fixedly connected to the upper end of the scraper 9, the guide wheel 903 is provided with four groups and is movably connected to the end surface of the scraper 9 away from the first motor 5 through the shaft structure.
[0037] Specifically, Figure 2 and Figure 6As shown, the scraper 9 is controlled by the driving gear 902 through the rack 904. The direction of the driving gear 902 directly affects the moving direction of the scraper 9. During the movement of the scraper 9, the slider 901 and the limiting slide groove 403 maintain stability, and the guide wheel 903 reduces the friction.
[0038] In this embodiment, the rack 904 is fixedly connected to the end face of one side away from the guide wheel 903, and meshes with the tooth groove of the driving gear 902, and the guide wheel 903 is embedded in the lateral limit groove 404; the upper end of the slider 901 passes through the upper end face of the sliding workbench 4, and establishes a sliding connection relationship with the limit slide groove 403; the end of the serial shaft 10 on one side facing the first motor 5 passes through the inner wall of the cooling pool 1 to establish a movable connection relationship with the first motor 5, and the serial shaft 10 is provided with a bearing structure at the position where the connection with the cooling pool 1 is established.
[0039] The working principle and use process of the present invention are as follows: when the device is used, the operator controls the first motor 5, the second motor 8, the refrigerator 6 and the fan 11 through the control panel 2, and introduces the filtrate after the heated enzymolysis into the cooling pool 1 through the pipeline connection port 3. The first motor 5 drives the serial shaft 10 to rotate, and the serial shaft 10 drives the fixed plate 1001 and the outer heat exhaust 1002 to rotate. The heat exhaust 1002 rotates continuously in the filtrate, and completes the heat exchange while stirring the inside of the filtrate. At the same time, the fan 11 continuously blows to the heat exhaust 1002 exposed on the surface of the filtrate, and makes the heat exhaust 1002 exposed on the surface of the filtrate quickly dissipate heat, and immerses it again in the filtrate during the slow rotation of the serial shaft 10 to complete the heat exchange, and when the filtrate is cooled, the heat exhaust 1002 is cooled by the fan 11. During the cooling process, the second motor 8 is started, and the scraper 9 is moved toward the surface of the filtrate through the connection between the driving gear 902 and the rack 904. The temperature at the bottom of the scraper 9 is much lower than the surface of the filtrate through the cooling of the refrigerator 6. At this time, the floating oil on the surface of the filtrate will quickly solidify and adsorb on its surface during the contact with the bottom of the scraper 9. Then the second motor 8 reverses and drives the scraper 9 to move toward the inside of the sliding workbench 4 through the driving gear 902. After being inserted into the embedding groove 401, the scraper 9 is continuously immersed in the oil scraping port 402, and the solidified grease at the bottom of the scraper 9 is scraped off at the oil scraping port 402 and finally falls into the cavity 405 below. The scraper 9 continuously repeats the above steps until the floating oil on the surface of the filtrate is removed, and the filtrate can be extracted when it drops to a suitable temperature.
[0040] Finally, it should be noted that the above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or replace some of the technical features therein by equivalents. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.
Claims
1. An automatic cooling device for producing sodium heparin, comprising a cooling pool (1), a control panel (2), and a pipe connection port (3), wherein the control panel (2) is arranged on the outer end surface of the cooling pool (1), the pipe connection port (3) is opened at the side end of the cooling pool (1), and a first motor (5) is arranged at the side end of the cooling pool (1), characterized in that: A sliding workbench (4) is arranged outside the cooling pool (1), a refrigerator (6) is arranged at the upper end of the sliding workbench (4), a gas pipeline (7) is arranged at the upper end of the refrigerator (6), a second motor (8) is arranged on the same side of the upper end of the sliding workbench (4), a scraper (9) is also arranged inside the cooling pool (1), a series connection shaft (10) is arranged on the inner wall of the cooling pool (1), and a fan (11) is arranged at the upper end of the side wall of the cooling pool (1); The serial shaft (10) further comprises a fixed disk (1001) and a heat sink (1002), wherein the fixed disk (1001) is fixedly connected to the outer end surface of the serial shaft (10), and the heat sink (1002) is fixedly connected to the side end of the fixed disk (1001).
2. The automatic cooling device for producing heparin sodium according to claim 1, characterized in that: The fixed disks (1001) are provided in two groups, the heat sinks (1002) are provided in five groups, and the single body is in a rectangular structure, with multiple groups of grooves extending inwardly arranged on the outer side, and the heat sinks (1002) are fixedly connected between the two fixed disks (1001).
3. The automatic cooling device for producing heparin sodium according to claim 1, characterized in that: The sliding workbench (4) further comprises an embedding groove (401), an oil scraping port (402), a limiting sliding groove (403), a lateral limiting groove (404) and a cavity (405); the embedding groove (401) is arranged on the inner side of the sliding workbench (4); the oil scraping port (402) is arranged on the inner side of the embedding groove (401); and the limiting sliding groove (403) is arranged on the top of the sliding workbench (4).
4. The automatic cooling device for producing heparin sodium according to claim 3, characterized in that: The lateral limiting groove (404) is provided on an end surface of the oil scraping port (402) away from the first motor (5), and the cavity (405) is provided inside the sliding workbench (4), and the rear end is connected to the upper end.
5. The automatic cooling device for producing heparin sodium according to claim 3, characterized in that: The embedding groove (401) and the oil scraping port (402) are connected front to back, and a side of the cavity (405) facing the cooling pool (1) is in a fixed connection with its edge.
6. The automatic cooling device for heparin sodium production according to claim 1, characterized in that: The scraper (9) further comprises a slider (901), a driving gear (902), a guide wheel (903) and a rack (904); the slider (901) is provided in two groups and is fixedly connected to the upper end of the scraper (9); the guide wheel (903) is provided in four groups and is movably connected to the end surface of the scraper (9) away from the first motor (5) through an axle structure.
7. The automatic cooling device for producing heparin sodium according to claim 6, characterized in that: The rack (904) is fixedly connected to a side end surface away from the guide wheel (903) and meshes with the tooth groove of the driving gear (902). The guide wheel (903) is embedded in the lateral limiting groove (404).
8. The automatic cooling device for producing heparin sodium according to claim 6, characterized in that: The upper end of the sliding block (901) passes through the upper end surface of the sliding workbench (4) and establishes a sliding connection relationship with the limiting sliding groove (403).
9. The automatic cooling device for producing heparin sodium according to claim 1, characterized in that: The end of the serial connection shaft (10) on one side facing the first motor (5) passes through the inner wall of the cooling pool (1) to establish a movable connection relationship with the first motor (5), and the serial connection shaft (10) is provided with a bearing structure at the position where the connection is established with the cooling pool (1).