Wet mixing granulator for amlodipine besylate tablets

Abstract

The utility model discloses a wet mixing granulator for amlodipine besylate tablets, which relates to the technical field of granulators and comprises a granulator main body, a circle of connecting net bag is fixedly connected to the top end of a sieve plate along the outer edge, a second motor is arranged in the granulator main body, the output end of the second motor is fixedly connected with a first straight cylinder, and the output end of the first straight cylinder is fixedly connected with a second straight cylinder. A second straight cylinder is arranged above the first straight cylinder, a connecting rod is fixedly connected to the top end of the second straight cylinder, a plurality of inclined ejector blocks are fixedly connected to the top end of the first straight cylinder, and a plurality of bevel grooves are formed in the bottom end of the second straight cylinder. And along with the movement of the inclined ejector block, the inclined ejector block crosses over the current bevel groove and is embedded into the next bevel groove, so that the second straight barrel moves up and down along the limiting assembly, raw materials on the sieve plate move and can smoothly pass through the sieve plate, and the sieving efficiency is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of granulators, in particular to a wet mixing granulator for amlodipine besylate tablets. Background Art

[0002] Amlodipine besylate is a dihydropyridine calcium antagonist, which mainly inhibits the calcium storage capacity and calcium ion binding capacity of myocardial and vascular smooth muscle cell membranes, and achieves the effect of lowering blood pressure by dilating vascular arterioles and reducing peripheral resistance. High-efficiency wet mixer granulator is a high-efficiency equipment that mixes different powdered materials and makes granules in one process. It is widely used in pharmaceutical, food, chemical and other industries. Wet granulation refers to the method of adding binder to drug powder and agglomerating the powder together by the bridging or bonding effect of the binder to prepare granules.

[0003] A Chinese patent (publication number: CN215277183U) discloses a wet mixing granulator for amlodipine besylate tablets, wherein a granulation chamber is arranged on a base, a first storage tank and a second storage tank are both arranged on the top surface of the granulation chamber, a controller is connected to a motor and arranged on one side of the base; a mixing device is arranged in the first storage tank and the second storage tank; a rotating stirring chassis is arranged at the center of the bottom of the granulation chamber, and an auxiliary rotating stirring member is arranged on the rotating chassis; a granulator is arranged at the bottom end of one side of the granulation chamber; a discharge port is opened below the granulator; the granulator can first mix the two parts of the material through the design of the storage tank, and then obtain the final material through the stirring and granulation of the granulation chamber, the operation is simple and convenient, the material mixing and granulation stirring effects are good, and the pharmaceutical efficiency is improved; the device is provided with a screen at the bottom of the storage tank to screen the raw materials, but the screen is easily blocked by large particles of raw materials, affecting the screening efficiency of the screen.

[0004] In order to solve the above problems, we have made improvements and proposed a wet mixing granulator for amlodipine besylate tablets. Utility Model Content

[0005] In order to solve the above technical problems, the utility model provides the following technical solutions:

[0006] The utility model provides a wet mixing granulator for amlodipine besylate tablets, comprising a granulator main body, the top of the granulator main body is fixedly connected with an intermediate box, the top of the intermediate box is fixedly connected with two storage tanks, a sieve plate is arranged inside the granulator main body, the top of the sieve plate is fixedly connected with a circle of connecting net bags along the outer edge, and the top of the connecting net bags is fixedly connected to the inside of the granulator main body, a second motor is arranged inside the granulator main body, the output end of the second motor is fixedly connected with a first straight cylinder, a second straight cylinder is arranged above the first straight cylinder, the top of the second straight cylinder is fixedly connected with a connecting rod, and the top of the connecting rod is rotatably connected to the sieve plate, the top of the first straight cylinder is fixedly connected with a plurality of inclined top blocks, the bottom end of the second straight cylinder is provided with a plurality of oblique grooves, and the oblique grooves cooperate with the oblique top blocks, and a limiting component is arranged on the outer side of the second straight cylinder.

[0007] As a preferred technical solution of the utility model, the limiting assembly includes a connecting sleeve, and the connecting sleeve is slidably connected to the outside of the second straight cylinder, and a plurality of second support rods are fixedly connected to the outside of the connecting sleeve, and the second support rods are fixedly connected to the inside of the granulator body.

[0008] As a preferred technical solution of the utility model, a plurality of first support rods are fixedly connected to the outer side of the second motor, and the first support rods are fixedly connected to the inside of the granulator body.

[0009] As a preferred technical solution of the utility model, a first motor is fixedly connected to the right side of the middle box, a rotating shaft is fixedly connected to the output end of the first motor, and the rotating shaft is rotatably connected to the inside of the middle box, and a pair of augers are fixedly connected to the outside of the rotating shaft, and the directions of the pair of augers are opposite.

[0010] As a preferred technical solution of the utility model, a protrusion is fixedly connected to the right side of the screen plate, a third motor is fixedly connected to the inner right part of the granulator body, a mounting wheel is fixedly connected to the output end of the third motor, a plurality of toggle plates are fixedly connected to the side of the mounting wheel, and the toggle plates cooperate with the protrusion.

[0011] As a preferred technical solution of the utility model, a spring is fixedly connected inside the second straight cylinder, and the bottom end of the spring is rotatably connected to the first straight cylinder through a connecting block.

[0012] As a preferred technical solution of the utility model, a baffle is hingedly connected to the front end of the granulator body, and a connecting piece is provided between the baffle and the granulator body.

[0013] The beneficial effects of the utility model are:

[0014] 1. In the utility model, the second motor drives the first straight cylinder to rotate, and the rotating first straight cylinder drives the inclined top block at the top to rotate. With the movement of the inclined top block, the inclined top block passes over the current inclined groove and is embedded in the next inclined groove, so that the second straight cylinder moves up and down along the limit assembly, and then the screen plate moves up and down through the connecting rod, so that the raw materials on the screen plate move, so that the raw materials can pass through the screen plate smoothly, thereby improving the screening efficiency.

[0015] 2. In the utility model, the raw materials in the two storage tanks flow into the middle box, and the first motor drives the rotating shaft to rotate. The rotating shaft causes the two augers to rotate at the same time, so that the two raw materials move toward the middle direction of the middle box at the same time and converge in the middle of the middle box, so that the two raw materials are pre-mixed to improve the mixing efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] The accompanying drawings are used to provide a further understanding of the present invention and constitute a part of the specification. Together with the embodiments of the present invention, they are used to explain the present invention and do not constitute a limitation of the present invention. In the accompanying drawings:

[0017] Figure 1 It is a three-dimensional diagram of the utility model;

[0018] Figure 2 It is a partial cross-sectional view of the utility model;

[0019] Figure 3 The utility model Figure 2 Enlarged view of point A in the middle;

[0020] Figure 4 It is a partial exploded view of the utility model;

[0021] In the figure: 1. pelletizing machine body; 2. baffle; 3. connecting piece; 4. intermediate box; 5. storage tank; 6. first motor; 7. rotating shaft; 8. auger; 9. sieve plate; 10. connecting net bag; 11. connecting sleeve; 12. second motor; 13. first support rod; 14. second support rod; 15. bump; 16. third motor; 17. mounting wheel; 18. toggle plate; 19. first straight cylinder; 20. inclined top block; 21. oblique groove; 22. second straight cylinder; 23. connecting rod; 24. spring. DETAILED DESCRIPTION

[0022] The preferred embodiments of the present invention are described below in conjunction with the accompanying drawings. It should be understood that the preferred embodiments described herein are only used to illustrate and explain the present invention, and are not used to limit the present invention.

[0023] Example: Figure 1-4As shown, a wet mixing granulator for amlodipine besylate tablets comprises a granulator body 1, the top of the granulator body 1 is fixedly connected with an intermediate box 4, the top of the intermediate box 4 is fixedly connected with two storage tanks 5, a sieve plate 9 is arranged inside the granulator body 1, the top of the sieve plate 9 is fixedly connected with a circle of connecting net bags 10 along the outer edge, and the top of the connecting net bags 10 is fixedly connected to the inside of the granulator body 1, a second motor 12 is arranged inside the granulator body 1, a first straight cylinder 19 is fixedly connected to the output end of the second motor 12, a second straight cylinder 22 is arranged above the first straight cylinder 19, a connecting rod 23 is fixedly connected to the top of the second straight cylinder 22, and the top of the connecting rod 23 is rotatably connected to the sieve plate 9, a plurality of inclined top blocks 20 are fixedly connected to the top of the first straight cylinder 19, a plurality of oblique grooves 21 are opened at the bottom of the second straight cylinder 22, and the oblique grooves 21 cooperate with the inclined top blocks 20, and a limiting component is arranged on the outside of the second straight cylinder 22;

[0024] The raw materials in the storage tank 5 fall into the intermediate box 4, and then fall onto the sieve plate 9 inside the granulator body 1. Under the screening action of the sieve plate 9, qualified raw materials fall down and are processed into granules by the granulator body 1. During the operation of the equipment, the second motor 12 drives the first straight cylinder 19 to rotate, and the rotating first straight cylinder 19 drives the inclined top block 20 at the top to rotate. With the movement of the inclined top block 20, the inclined top block 20 passes over the current oblique groove 21 and is embedded in the next oblique groove 21, so that the second straight cylinder 22 moves up and down along the limit assembly, and then the sieve plate 9 moves up and down through the connecting rod 23, so that the raw materials on the sieve plate 9 move, so that the raw materials can pass through the sieve plate 9 smoothly, thereby improving the screening efficiency.

[0025] Specifically, Figure 2 As shown, the limiting assembly includes a connecting sleeve 11, and the connecting sleeve 11 is slidably connected to the outside of the second straight cylinder 22, and a plurality of second support rods 14 are fixedly connected to the outside of the connecting sleeve 11, and the second support rods 14 are fixedly connected to the inside of the granulator body 1, and the connecting sleeve 11 is sleeved on the outside of the second straight cylinder 22 and is fixed to the inside of the granulator body 1 by the second support rods 14, so as to limit the second straight cylinder 22 so that the second straight cylinder 22 can only move up and down.

[0026] Specifically, Figure 2 As shown, a plurality of first support rods 13 are fixedly connected to the outer side of the second motor 12 , and the first support rods 13 are fixedly connected to the inside of the granulator body 1 to fix the second motor 12 .

[0027] Specifically, Figure 2As shown, a first motor 6 is fixedly connected to the right side of the middle box 4, and a rotating shaft 7 is fixedly connected to the output end of the first motor 6, and the rotating shaft 7 is rotatably connected to the inside of the middle box 4. A pair of augers 8 are fixedly connected to the outside of the rotating shaft 7, and the directions of the pair of augers 8 are opposite. The raw materials in the two storage tanks 5 flow into the middle box 4, and the first motor 6 drives the rotating shaft 7 to rotate. The rotating rotating shaft 7 causes the two augers 8 to rotate at the same time, so that the two raw materials move toward the middle direction of the middle box 4 at the same time, and converge in the middle of the middle box 4, so that the two raw materials are pre-mixed to improve the mixing efficiency.

[0028] Specifically, Figure 3 As shown, a protrusion 15 is fixedly connected to the right side of the sieve plate 9, a third motor 16 is fixedly connected to the inner right part of the granulator body 1, and a mounting wheel 17 is fixedly connected to the output end of the third motor 16. A plurality of toggle plates 18 are fixedly connected to the side of the mounting wheel 17, and the toggle plates 18 cooperate with the protrusion 15. The heights of the toggle plates 18 and the protrusion 15 are greater than the height of the inclined top block 20. The third motor 16 drives the mounting wheel 17 to rotate, and the rotating mounting wheel 17 drives the toggle plate 18 to move. The moving toggle plate 18 acts on the protrusion 15, thereby toggling the sieve plate 9 to make a circumferential movement, thereby further improving the screening efficiency.

[0029] Specifically, Figure 4 As shown, a spring 24 is fixedly connected to the interior of the second straight cylinder 22, and the bottom end of the spring 24 is rotatably connected to the first straight cylinder 19 through a connecting block. The first straight cylinder 19 and the second straight cylinder 22 are connected through the spring 24, so that the second straight cylinder 22 is improved in its descent efficiency, thereby increasing the vibration frequency of the screen plate 9 and improving the screening efficiency.

[0030] Specifically, Figure 1 As shown, a baffle 2 is hinged at the front end of the granulator body 1, and a connecting piece 3 is provided between the baffle 2 and the granulator body 1. The baffle 2 can be opened to remove unqualified raw materials on the sieve plate 9 for easy cleaning.

[0031] Working principle: the raw materials in the storage tank 5 fall into the middle box 4, the first motor 6 works to drive the rotating shaft 7 to rotate, the rotating rotating shaft 7 makes the two screw dragons 8 rotate at the same time, so that the two raw materials move toward the middle direction of the middle box 4 at the same time, converge in the middle of the middle box 4, and then fall into the sieve plate 9 inside the granulator body 1, the second motor 12 works to drive the first straight cylinder 19 to rotate, the rotating first straight cylinder 19 drives the inclined top block 20 at the top to rotate, with the movement of the inclined top block 20, the inclined top block 20 passes over the current oblique groove 21, and is embedded in the next oblique groove 21, so that the second straight cylinder 22 moves up and down along the limit assembly, the third motor 16 works to drive the mounting wheel 17 to rotate, the rotating mounting wheel 17 drives the toggle plate 18 to move, the moving toggle plate 18 acts on the protrusion 15, and then toggle the sieve plate 9 to make a circumferential movement, so that the raw materials on the sieve plate 9 move, so that the raw materials can pass through the sieve plate 9 smoothly, thereby improving the screening efficiency.

[0032] Finally, it should be noted that the above description is only a preferred embodiment of the utility model and is not intended to limit the utility model. Although the utility model is described in detail with reference to the above embodiments, those skilled in the art can still modify the technical solutions recorded in the above embodiments or replace some of the technical features therein by equivalents. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the utility model shall be included in the protection scope of the utility model.

Claims

1. A wet mixing granulator for amlodipine besylate tablets, comprising a granulator body (1), characterized in that: The top of the granulator body (1) is fixedly connected to an intermediate box (4), and the top of the intermediate box (4) is fixedly connected to two material storage tanks (5). A sieve plate (9) is arranged inside the granulator body (1), and a circle of connecting net bags (10) are fixedly connected to the top of the sieve plate (9) along the outer edge, and the top of the connecting net bag (10) is fixedly connected to the inside of the granulator body (1). A second motor (12) is arranged inside the granulator body (1), and the output end of the second motor (12) is fixedly connected to the first A straight cylinder (19), a second straight cylinder (22) is arranged above the first straight cylinder (19), a connecting rod (23) is fixedly connected to the top end of the second straight cylinder (22), and the top end of the connecting rod (23) is rotatably connected to the screen plate (9), a plurality of inclined top blocks (20) are fixedly connected to the top end of the first straight cylinder (19), a plurality of inclined grooves (21) are opened at the bottom end of the second straight cylinder (22), and the inclined grooves (21) cooperate with the inclined top blocks (20), and a limiting component is arranged on the outer side of the second straight cylinder (22).

2. A wet mixing granulator for amlodipine besylate tablets according to claim 1, characterized in that: The limiting assembly comprises a connecting sleeve (11), and the connecting sleeve (11) is slidably connected to the outside of the second straight cylinder (22), and a plurality of second support rods (14) are fixedly connected to the outside of the connecting sleeve (11), and the second support rods (14) are fixedly connected to the inside of the granulator body (1).

3. A wet mixing granulator for amlodipine besylate tablets according to claim 1, characterized in that: A plurality of first support rods (13) are fixedly connected to the outer side of the second motor (12), and the first support rods (13) are fixedly connected to the inside of the granulator body (1).

4. The wet mixing granulator for amlodipine besylate tablets according to claim 1, characterized in that: A first motor (6) is fixedly connected to the right side of the middle box (4); a rotating shaft (7) is fixedly connected to the output end of the first motor (6); and the rotating shaft (7) is rotatably connected to the inside of the middle box (4); a pair of augers (8) are fixedly connected to the outside of the rotating shaft (7); and the directions of the pair of augers (8) are opposite.

5. The wet mixing granulator for amlodipine besylate tablets according to claim 1, characterized in that: A protrusion (15) is fixedly connected to the right side of the sieve plate (9), a third motor (16) is fixedly connected to the inner right part of the granulator body (1), an output end of the third motor (16) is fixedly connected to a mounting wheel (17), a plurality of toggle plates (18) are fixedly connected to the side of the mounting wheel (17), and the toggle plates (18) cooperate with the protrusion (15).

6. The wet mixing granulator for amlodipine besylate tablets according to claim 1, characterized in that: A spring (24) is fixedly connected inside the second straight cylinder (22), and the bottom end of the spring (24) is rotatably connected to the first straight cylinder (19) via a connecting block.

7. The wet mixing granulator for amlodipine besylate tablets according to claim 1, characterized in that: A baffle (2) is hingedly connected to the front end of the granulator body (1), and a connecting piece (3) is provided between the baffle (2) and the granulator body (1).

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