Cryopreservation device for NK cells

Abstract

The utility model relates to the technical field of biomedical treatment, in particular to a cryopreservation device for NK (Natural Killer) cells, which comprises a refrigeration sleeve, an outlet sleeve is fixedly clamped at the upper end of the refrigeration sleeve, and an auxiliary taking-out device is sleeved in the outlet sleeve; the lower end of the sealing cover is fixedly connected with a plurality of sealing sleeves, and the sealing sleeves are correspondingly inserted into the outlet sleeve in a sealing manner; the cryopreservation device for the NK cells has the advantages that due to the fact that the auxiliary taking-out device is arranged, when the test tubes need to be taken out, workers can take out the cryopreservation test tubes without wearing equipment or using tools, meanwhile, the cryopreservation device does not need to be completely opened, the cryopreservation test tubes can be taken out, heat exchange is reduced, and the working efficiency is improved. And the cooling efficiency is improved.

Description

Technical Field

[0001] The utility model relates to the field of biomedicine, in particular to a freezing device for NK cells. Background Art

[0002] NK cells, or natural killer cells, are a type of innate lymphoid cells that can spontaneously kill target cells without prior antigen sensitization, hence the name natural killer cells. Cell cryopreservation is a technique that places cells in a low-temperature environment to reduce cell metabolism for long-term storage. Cell cryopreservation is one of the main methods of cell preservation and plays an important role in cell preservation. In order to store NK cells for a long time, a cell cryopreservation device is required for cryopreservation.

[0003] When taking out the cryopreservation tubes in the traditional cell cryopreservation device, due to the low temperature inside the cryopreservation device, the staff needs to wear certain equipment or use tools to take out the cryopreservation tubes, and the operation is relatively complicated. In addition, since the device needs to be fully opened, the interior absorbs more external heat, which reduces the cryopreservation efficiency. Therefore, the utility model proposes a cryopreservation device for NK cells to solve the above problems. Utility Model Content

[0004] The purpose of the utility model is to provide a freezing device for NK cells to solve the problems raised in the above background technology.

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a freezing device for NK cells, the freezing device for NK cells comprising: a refrigeration sleeve, the upper end of which is fixedly connected with an outlet sleeve, the inner sleeve of which is provided with an auxiliary removal device; a sealing cover, the lower end of which is fixedly connected with a plurality of sealing sleeves, and the sealing sleeves are correspondingly sealed and plugged into the outlet sleeve.

[0006] Preferably, the auxiliary removal device includes a rotating knob, the lower end of the rotating knob is fixedly connected to a transmission rod, the lower end of the transmission rod is rotatably sleeved on the upper end surface of the outlet sleeve, the outer end of the bottom side of the transmission rod is fixedly connected to a rotating gear, the rotating gear corresponding to the gear is connected to a screw gear, the upper end of the screw gear is fixedly connected to a transmission screw, and the upper end of the transmission screw is rotatably sleeved with a screw knob.

[0007] Preferably, a transmission sleeve is provided on the outer threaded sleeve of the transmission screw, a lifting sleeve is provided on the left sliding sleeve of the transmission sleeve, a buffer groove is provided on the right side of the lifting sleeve, and a transmission sleeve is provided on the sliding sleeve in the buffer groove.

[0008] Preferably, a cryopreservation test tube is provided inside the lifting sleeve.

[0009] Preferably, a plurality of threaded holes are provided at the upper end of the outlet sleeve, and a screw knob is provided in the threaded sleeve within the threaded hole.

[0010] Compared with the prior art, the beneficial effects of the utility model are:

[0011] The cryopreservation device for NK cells proposed by the utility model is provided with an auxiliary taking-out device, so that when the test tube needs to be taken out, the staff can take out the cryopreserved test tube without wearing equipment or using tools, and the cryopreservation test tube can be taken out without completely opening the cryopreservation device, thereby reducing heat exchange and improving cooling efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] Figure 1 This is a schematic diagram of the main structure of the utility model;

[0013] Figure 2 This is a schematic diagram of the internal structure of the utility model;

[0014] Figure 3 for Figure 2 The enlarged schematic diagram at A in the middle;

[0015] Figure 4 It is a partial structural schematic diagram of the utility model.

[0016] In the figure: 1 sealing cover, 2 sealing plug, 3 outlet sleeve, 4 refrigeration sleeve, 5 turning knob, 6 screw knob,

[0017] 7 freezing test tube, 8 lifting sleeve, 9 transmission rod, 10 rotating gear, 11 transmission screw, 12 transmission sleeve, 13 buffer slide groove, 14 screw gear, 15 threaded hole. DETAILED DESCRIPTION

[0018] In order to make the purpose and technical solution of the utility model clearly and completely described, and the advantages more clearly understood, the embodiments of the utility model are further described in detail in conjunction with the accompanying drawings. It should be understood that the specific embodiments described here are part of the embodiments of the utility model, not all of the embodiments, and are only used to explain the embodiments of the utility model, and are not used to limit the embodiments of the utility model. All other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0019] Embodiment 1

[0020] See also Figure 1-Figure 3 The utility model provides a technical solution: a freezing device for NK cells, which includes: a refrigeration sleeve 4, the upper end of which is fixedly connected with an outlet sleeve 3, and the inner sleeve of the outlet sleeve 3 is provided with an auxiliary removal device; a sealing cover 1, the lower end of the sealing cover 1 is fixedly connected with a plurality of sealing sleeves 2, and the sealing sleeves 2 are correspondingly sealed and plugged into the outlet sleeve 3, and the sealing cover 1 is used to play a role of heat preservation and sealing for the refrigeration sleeve 4.

[0021] Embodiment 2

[0022] On the basis of the first embodiment, the auxiliary removal device includes a rotating knob 5, the lower end of the rotating knob 5 is fixedly connected to a transmission rod 9, the lower end of the transmission rod 9 is rotatably sleeved on the upper end surface of the outlet sleeve 3, the outer end of the bottom side of the transmission rod 9 is fixedly connected to a rotating gear 10, the corresponding gear of the rotating gear 10 is connected to a screw gear 14, the upper end of the screw gear 14 is fixedly connected to a transmission screw 11, the upper end of the transmission screw 11 is rotatably sleeved with a screw knob 6, the outer thread sleeve of the transmission screw 11 is provided with a transmission sleeve 12, the sliding sleeve on the left side of the transmission sleeve 12 is provided with a lifting sleeve 8, and the lifting sleeve 8 is provided. A buffer chute 13 is provided on the right side of the lowering sleeve 8, and a transmission sleeve 12 is provided in the sliding sleeve of the buffer chute 13. A plurality of threaded holes 15 are provided on the upper end of the outlet sleeve 3, and a screw knob 6 is provided in the threaded sleeve of the threaded hole 15. When it is necessary to take out the specified frozen test tube 7, it is necessary to first specify the screw knob 6 on one side of the frozen test tube 7 so that the screw gear 14 descends and the corresponding gear of the rotating gear 10 is engaged. Then, the rotating knob 5 is adjusted so that the rotating gear 10 drives the transmission screw 11 to rotate, and the lifting sleeve 8 is driven to rise through the transmission sleeve 12, so that the removal can be achieved.

[0023] Embodiment 3

[0024] On the basis of the second embodiment, a cryopreservation test tube 7 is provided inside the lifting sleeve 8, and when the lifting sleeve 8 is raised, the cryopreservation test tube 7 can be taken out manually.

[0025] In actual use, when it is necessary to take out the specified freezing test tube 7, it is necessary to first specify the screw knob 6 on one side of the freezing test tube 7, so that the screw gear 14 descends and the corresponding gear of the rotating gear 10 is engaged, and then the rotating knob 5 is adjusted so that the rotating gear 10 drives the transmission screw 11 to rotate, and the lifting sleeve 8 is driven to rise through the transmission sleeve 12, so that the taking out can be achieved. When it is necessary to place the freezing test tube 7, the freezing test tube 7 is placed in the lifting sleeve 8, and the rotating knob 5 is adjusted to achieve the descent. When it is completely descended, the screw knob 6 is adjusted again to release the gear connection between the screw gear 14 and the rotating gear 10.

[0026] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A freezing device for NK cells, characterized in that: The freezing device for NK cells comprises: A refrigeration sleeve (4), wherein the upper end of the refrigeration sleeve (4) is fixedly connected with an outlet sleeve (3), and an auxiliary removal device is provided inside the outlet sleeve (3); A sealing cover (1), wherein a plurality of sealing sleeves (2) are fixedly connected to the lower end of the sealing cover (1), and the sealing sleeves (2) are correspondingly sealed and inserted into the outlet sleeve (3).

2. A freezing device for NK cells according to claim 1, characterized in that: The auxiliary removal device comprises a rotating knob (5), the lower end of which is fixedly connected to a transmission rod (9), the lower end of which is rotatably sleeved on the upper end surface of an outlet sleeve (3), the outer end of the bottom side of the transmission rod (9) is fixedly connected to a rotating gear (10), the corresponding gear of the rotating gear (10) is connected to a screw gear (14), the upper end of the screw gear (14) is fixedly connected to a transmission screw (11), and the upper end of the transmission screw (11) is rotatably sleeved with a screw knob (6).

3. A freezing device for NK cells according to claim 2, characterized in that: The outer thread sleeve of the transmission screw (11) is provided with a transmission sleeve (12), the left sliding sleeve of the transmission sleeve (12) is provided with a lifting sleeve (8), the right side of the lifting sleeve (8) is provided with a buffer sliding groove (13), and the sliding sleeve in the buffer sliding groove (13) is provided with the transmission sleeve (12).

4. A freezing device for NK cells according to claim 3, characterized in that: The lifting sleeve (8) is provided with a cryopreservation test tube (7) inside.

5. A freezing device for NK cells according to claim 1, characterized in that: A plurality of threaded holes (15) are provided at the upper end of the outlet sleeve (3), and a screw knob (6) is provided in the threaded sleeve of the threaded hole (15).

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