Reaction kettle of purification instrument

Abstract

The utility model discloses a purification instrument reaction kettle which comprises a kettle body, a support, a driving assembly, a lifting assembly and a stirring assembly, the driving assembly is installed on the support, the lifting assembly is installed on the support and connected with the output end of the driving assembly, the stirring assembly is located in the kettle body, and the stirring assembly and the driving assembly are coaxially arranged and circumferentially connected. One side of the stirring assembly is connected with the lifting assembly, when the driving assembly moves, the stirring assembly rotates and stirs along with the driving assembly, and meanwhile, the lifting assembly moves along with the driving assembly to synchronously drive the stirring assembly to reciprocate up and down in the kettle body. While the stirring blades rotate horizontally, reciprocating motion in the longitudinal direction can be synchronously achieved, liquid is driven to be disturbed in the horizontal direction and the longitudinal direction, and therefore bottom deposition of protein and binding liquid is avoided, and stirring is more uniform.

Description

Technical Field

[0001] The utility model relates to the technical field of purification equipment, in particular to a reaction kettle of a purification instrument. Background Art

[0002] When performing protein detection operations, in order to ensure the accuracy of the test results and avoid adverse effects of other impurities on the test results, it is often necessary to purify the protein through a purifier. When purifying proteins, it is necessary to stir and mix the purified liquid and the reactant through a stirring tank. Currently, most stirring tanks stir in a unidirectional horizontal direction and cannot stir in the vertical direction, resulting in sedimentation of the reactant at the bottom and uneven stirring reaction, which affects the purification efficiency and quality. Utility Model Content

[0003] In order to overcome the deficiencies of the prior art, the utility model aims to achieve a purification apparatus reactor that can stir liquid synchronously in the horizontal and vertical directions to avoid bottom sedimentation and allow proteins to be stirred evenly.

[0004] The purpose of the utility model is achieved by the following technical solutions:

[0005] A purification instrument reactor comprises a reactor body, and also comprises a bracket, a driving component, a lifting component and a stirring component, wherein the driving component is mounted on the bracket, the lifting component is mounted on the bracket and connected to the output end of the driving component, the stirring component is located in the reactor body, the stirring component is coaxially arranged with the driving component and circumferentially connected, one side of the stirring component is connected to the lifting component, when the driving component moves, the stirring component follows the driving component to rotate and stir, and at the same time the lifting component follows the driving component to move, and while the stirring component rotates and stirs, the stirring component is synchronously driven to reciprocate up and down in the reactor body.

[0006] Furthermore, the driving assembly includes a driving motor and a cross-axis rod, the driving motor is located above the bracket, and the cross-axis rod is located below the bracket and connected to the driving motor.

[0007] Furthermore, the lifting assembly includes a driven gear, a reciprocating screw and a transmission member, the driving assembly also includes a driving gear, the driving gear is transmission-connected to the output end of the driving motor, the driven gear is meshed with the driving gear, the reciprocating screw is coaxially connected to the driven gear, and the transmission member is located below the reciprocating screw and reciprocates up and down with the reciprocating screw.

[0008] Furthermore, the transmission member includes a threaded sleeve, a connecting rod and a hoop, the threaded sleeve and the reciprocating screw are meshed with each other, the connecting rod is located on one side of the threaded sleeve and connected to the threaded sleeve, and the other end of the connecting rod is connected to the hoop.

[0009] Furthermore, the stirring assembly includes a stirring shaft and stirring blades, the stirring shaft is sleeved on the cross shaft, and the stirring blades are located at the bottom of the stirring shaft.

[0010] Furthermore, the stirring blade comprises a first stirring blade and a second stirring blade, the second stirring blade is located inside the first stirring blade, and the second stirring blade is detachably connected to the first stirring blade.

[0011] Furthermore, the angle between the stirring blade and the horizontal plane is an acute angle.

[0012] Furthermore, the stirring assembly also includes a sleeve rod, which is connected to the top of the stirring shaft rod, and the sleeve hoop is sleeved on the sleeve rod. The end of the sleeve rod has a limiting blocking plate for limiting the position of the sleeve hoop.

[0013] Furthermore, the plane where the driving assembly is located is parallel to the plane where the lifting assembly is located.

[0014] Furthermore, the kettle body includes a shell and a cover plate, the cover plate is installed on the top of the shell, the cover plate is provided with a plurality of liquid inlet hoppers for inputting liquid, the shell is funnel-shaped, and the cross-sectional diameter of the shell gradually decreases from top to bottom.

[0015] Compared with the prior art, the purifier reactor of the utility model has the following advantages:

[0016] (1) The purifier reactor of the present application drives the driving gear and the cross shaft to rotate synchronously through the driving motor, driving the stirring shaft to rotate horizontally, so that the stirring blade follows the stirring shaft to make horizontal rotational motion, and at the same time, the driving gear drives the driven gear to move, driving the reciprocating screw to rotate. While the reciprocating screw rotates, the transmission member follows the axial movement of the reciprocating screw to drive the stirring shaft to make reciprocating up and down motion in the longitudinal direction, and then while the stirring blade rotates horizontally, it also realizes reciprocating motion in the longitudinal direction synchronously, driving the liquid to be disturbed in the horizontal and longitudinal directions, thereby avoiding the deposition of protein and binding liquid at the bottom, making the stirring more uniform;

[0017] (2) The shell of the purification apparatus reactor of the present application is funnel-shaped, and the cross-sectional diameter of the shell gradually decreases from top to bottom. Through the two sections of the first cavity and the second cavity with different diameters, it can adapt to different liquid volumes of proteins to be purified. The liquid inlet on the cover is used to add the protein to be purified and the reaction liquid. Among them, the funnel shape can facilitate the pouring of liquid, reduce the splashing and waste of liquid / reduce the splashing of liquid when pouring into the shell, making the operation cleaner and safer, and can also save space and facilitate storage and use;

[0018] (3) The purifier reactor of the present application can scrape off the liquid substance attached to the inner wall of the shell through the freely retractable second stirring blade, thereby preventing impurities from being attached to the inner wall of the shell. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 This is a schematic diagram of the structure of the reactor of the purifier of the utility model;

[0020] Figure 2 It is a schematic diagram of the assembly structure of the driving component and the stirring component of the reactor of the purifier of the utility model;

[0021] Figure 3 It is a structural schematic diagram of the lifting assembly of the reactor of the purifier of the utility model;

[0022] Figure 4 It is a schematic diagram of the expanded state of the stirring blades of the purifier reactor of the utility model.

[0023] In the figure: 100, kettle body; 110, shell; 111, first cavity; 112, second cavity; 120, cover plate; 121, liquid inlet bucket; 200, bracket; 300, drive assembly; 310, drive motor; 320, driving gear; 330, cross shaft; 400, lifting assembly; 410, driven gear; 420, reciprocating screw; 430, transmission member; 431, threaded sleeve; 432, connecting rod; 433, hoop; 500, stirring assembly; 510, stirring shaft; 520, stirring blade; 521, first stirring blade; 522, second stirring blade; 530, sleeve rod; 531, limit blocking plate. DETAILED DESCRIPTION

[0024] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0025] It should be noted that when a component is referred to as being "fixed to" another component, it may be directly on the other component or there may be another intermediate component through which it is fixed. When a component is considered to be "connected to" another component, it may be directly connected to the other component or there may be another intermediate component at the same time. When a component is considered to be "set on" another component, it may be directly set on the other component or there may be another intermediate component at the same time. The terms "vertical", "horizontal", "left", "right" and similar expressions used herein are for illustrative purposes only.

[0026] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those commonly understood by those skilled in the art in the technical field of the present invention. The terms used herein in the specification of the present invention are only for the purpose of describing specific embodiments and are not intended to limit the present invention. The term "and / or" used herein includes any and all combinations of one or more related listed items.

[0027] Figure 1 to Figure 4 The reactor of the purifier of the utility model is as follows: Figure 1 As shown, the purifier reactor includes a reactor body 100, a bracket 200, a drive assembly 300, a lifting assembly 400 and a stirring assembly 500. The bracket 200 is located above the reactor body 100 and is fixedly connected to the reactor body 100. The drive assembly 300 and the lifting assembly 400 are located on the bracket 200 and are fixedly connected to the bracket 200. The bracket 200 is used to support and install the drive assembly 300 and the lifting assembly 400.

[0028] Specifically, the plane where the driving assembly 300 is located is parallel to the plane where the lifting assembly 400 is located.

[0029] In some other embodiments, the bracket 200 is located at one side of the kettle body 100 and fixed on a base, the bracket 200 extends above the kettle body 100 , and the driving assembly 300 and the lifting assembly 400 are fixed on the bracket 200 .

[0030] The kettle body 100 includes a shell 110 and a cover plate 120 . The cover plate 120 is installed on the top of the shell 110 . The cover plate 120 is provided with a plurality of liquid inlet hoppers 121 for inputting liquid.

[0031] Specifically, the shell 110 is funnel-shaped, and the cross-sectional diameter of the shell 110 gradually decreases from top to bottom. The shell 110 includes a first cavity 111 and a second cavity 112, the first cavity 111 is located at the upper part of the shell 110, and the second cavity 112 is located at the lower part of the shell 110. The first cavity 111 and the second cavity 112 have two sections of space with different diameters, which can adapt to different liquid volumes of proteins that need to be purified. The liquid inlet hopper 121 on the cover plate 120 is used to add proteins that need to be purified and reaction liquid. Among them, the funnel shape can facilitate pouring liquid, reduce splashing and waste of liquid / reduce splashing when liquid is poured into the shell 110, making the operation cleaner and safer, and can also save space, and is convenient for storage and use.

[0032] like Figure 2 As shown, the driving assembly 300 includes a driving motor 310 , a driving gear 320 and a cross shaft 330 . The driving gear 320 is drivingly connected to the output end of the driving motor 310 . The cross shaft 330 is located below the driving gear 320 and is coaxially connected to the driving gear 320 .

[0033] like Figure 3 As shown, the lifting assembly 400 includes a driven gear 410, a reciprocating screw 420 and a transmission member 430. The driven gear 410 is meshed with the driving gear 320, the reciprocating screw 420 is coaxially connected to the driven gear 410, and the transmission member 430 is located below the reciprocating screw 420 and reciprocates up and down with the reciprocating screw 420.

[0034] Specifically, the driven gear 410 and the driving gear 320 are arranged horizontally.

[0035] The transmission member 430 includes a threaded sleeve 431, a connecting rod 432 and a hoop 433. The threaded sleeve 431 is located at the bottom of the reciprocating screw 420 and meshes with the reciprocating screw 420, which can strengthen the connection part with the reciprocating screw 420 so that it can withstand greater pressure and torque.

[0036] The connecting rod 432 is located at one side of the threaded sleeve 431 and connected to the threaded sleeve 431 , and the other end of the connecting rod 432 is connected to the hoop 433 .

[0037] Specifically, the connecting rod 432 is arranged horizontally.

[0038] like Figure 2 As shown, the stirring assembly 500 is located in the housing 110 and directly below the driving assembly 300 . The stirring assembly 500 includes a stirring shaft 510 and a stirring blade 520 . The stirring shaft 510 is sleeved on the cross shaft 330 , and the stirring blade 520 is located at the bottom of the stirring shaft 510 .

[0039] Specifically, the stirring assembly 500 is coaxially connected to the driving assembly 300 .

[0040] like Figure 4 As shown, the stirring blade 520 includes a first stirring blade 521 and a second stirring blade 522, and the second stirring blade 522 is installed in the first stirring blade 521 and is pulled out from the first stirring blade 521. When the first cavity 111 at the upper part of the housing 110 is stirred, due to the centrifugal force of stirring, the second stirring blade 522 extends from the first stirring blade 521, and at this time, the outer wall of the second stirring blade 522 fits with the inner wall of the first cavity 111, and the liquid substance attached to the inner wall of the first cavity 111 can be scraped off. Similarly, when the stirring blade 520 enters the second cavity 112, the second stirring blade 522 shrinks into the first stirring blade 521, and the outer wall of the first stirring blade 521 contacts the inner wall of the second cavity 112, so as to prevent impurities from being attached to the inner wall of the second cavity 112.

[0041] Specifically, the first stirring blade 521 and the second stirring blade 522 are detachably connected.

[0042] In a preferred embodiment, the angle between the stirring blade 520 and the horizontal plane is an acute angle.

[0043] Specifically, there are a plurality of first stirring blades 521 , and preferably, there are three first stirring blades 521 .

[0044] Specifically, the number of the second stirring blades 522 is the same as the number of the first stirring blades 521 .

[0045] The stirring assembly 500 further includes a sleeve rod 530 , which is connected to the top of the stirring shaft 510 . The sleeve hoop 433 is sleeved on the sleeve rod 530 . The end of the sleeve rod 530 has a limiting blocking plate 531 for limiting the position of the sleeve hoop 433 .

[0046] When the driving assembly 300 moves, the stirring assembly 500 follows the driving assembly 300 to rotate and stir, and at the same time, the lifting assembly 400 follows the driving assembly 300 to move, and while the stirring assembly 500 rotates and stirs, the stirring assembly 500 is synchronously driven to reciprocate up and down in the shell 110.

[0047] When the present application is in use, the protein to be purified and the binding liquid are transported into the shell 110 through the liquid inlet hopper 121, and then the driving motor 310 is started. The driving motor 310 drives the driving gear 320 and the cross shaft 330 to rotate synchronously. At this time, the cross shaft 330 drives the stirring shaft 510 to rotate horizontally, so that the stirring blade 520 follows the stirring shaft 510 to perform horizontal rotational movement, and the protein and the binding liquid are horizontally stirred. At the same time, the driving gear 320 drives the driven gear 410 to move, and drives the reciprocating screw 420 to rotate. While the reciprocating screw 420 rotates, the transmission member 430 follows the axial movement of the reciprocating screw 420 to drive the stirring shaft 510 to reciprocate up and down in the longitudinal direction, and then while the stirring blade 520 rotates horizontally, it reciprocates in the longitudinal direction synchronously, driving the liquid to be disturbed in the horizontal and longitudinal directions, thereby avoiding the bottom deposition of the protein and the binding liquid, and making the stirring more uniform. The shell 110 of the purifier reactor of the present application is funnel-shaped, and the cross-sectional diameter of the shell 110 gradually decreases from top to bottom. Through the two sections of the first cavity 111 and the second cavity 112 with different diameters, it can adapt to different liquid volumes of proteins to be purified. The liquid inlet 121 on the cover plate 120 is used to add the protein to be purified and the reaction liquid. Among them, the funnel shape can facilitate the pouring of liquid, reduce the splashing and waste of liquid / reduce the splashing of liquid when pouring into the shell 110, making the operation cleaner and safer, and can also save space, and is easy to store and use; through the freely retractable second stirring blade 522, the liquid substance attached to the inner wall of the shell 110 can be scraped off to avoid impurities attached to the inner wall of the shell 110.

[0048] The above embodiments only express several implementation methods of the utility model, and the descriptions are relatively specific and detailed, but they cannot be understood as limiting the scope of the utility model patent. It should be pointed out that for ordinary technicians in this field, without departing from the concept of the utility model, several modifications and improvements can be made, which are equivalent modifications and improvements made to the above embodiments based on the essential technology of the utility model, and all of them belong to the protection scope of the utility model.

Claims

1. A purifier reactor, comprising a reactor body, characterized in that: It also includes a bracket, a driving component, a lifting component and a stirring component, wherein the driving component is mounted on the bracket, the lifting component is mounted on the bracket and connected to the output end of the driving component, the stirring component is located in the kettle body, the stirring component is coaxially arranged with the driving component and circumferentially connected, one side of the stirring component is connected to the lifting component, when the driving component moves, the stirring component follows the driving component to rotate and stir, and the lifting component follows the driving component to move, and while the stirring component rotates and stirs, the stirring component is synchronously driven to reciprocate up and down in the kettle body.

2. The purifier reactor according to claim 1, characterized in that: The driving assembly comprises a driving motor and a cross shaft, wherein the driving motor is located above the bracket, and the cross shaft is located below the bracket and connected to the driving motor.

3. The purifier reactor according to claim 2, characterized in that: The lifting assembly includes a driven gear, a reciprocating screw and a transmission member. The driving assembly also includes a driving gear. The driving gear is transmission-connected to the output end of the driving motor. The driven gear and the driving gear are meshed with each other. The reciprocating screw is coaxially connected to the driven gear. The transmission member is located below the reciprocating screw and reciprocates up and down with the reciprocating screw.

4. The purifier reactor according to claim 3, characterized in that: The transmission member includes a threaded sleeve, a connecting rod and a hoop. The threaded sleeve is meshed with the reciprocating screw rod. The connecting rod is located at one side of the threaded sleeve and connected to the threaded sleeve. The other end of the connecting rod is connected to the hoop.

5. The purifier reactor according to claim 4, characterized in that: The stirring assembly comprises a stirring shaft and stirring blades. The stirring shaft is sleeved on the cross shaft, and the stirring blades are located at the bottom of the stirring shaft.

6. The purifier reactor according to claim 5, characterized in that: The stirring blade comprises a first stirring blade and a second stirring blade, wherein the second stirring blade is located inside the first stirring blade, and the second stirring blade is detachably connected to the first stirring blade.

7. The purifier reactor according to claim 5, characterized in that: The angle between the stirring blade and the horizontal plane is an acute angle.

8. The purifier reactor according to claim 5, characterized in that: The stirring assembly also includes a sleeve rod, which is connected to the top of the stirring shaft rod, and the sleeve hoop is sleeved on the sleeve rod. The end of the sleeve rod is provided with a limiting blocking plate for limiting the position of the sleeve hoop.

9. The purifier reactor according to claim 1, characterized in that: The plane where the driving assembly is located is parallel to the plane where the lifting assembly is located.

10. The purifier reactor according to claim 1, characterized in that: The kettle body comprises a shell and a cover plate, wherein the cover plate is mounted on the top of the shell, and the cover plate is provided with a plurality of liquid inlet hoppers for feeding liquid. The shell is funnel-shaped, and the cross-sectional diameter of the shell gradually decreases from top to bottom.

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