Accurate detection device for content of 5-aminolevulinic acid

Abstract

The utility model relates to the technical field of content detection, and discloses an accurate detection device for the content of 5-aminolevulinic acid, which solves the problem that a 5-aminolevulinic acid sample and a reagent are not uniformly mixed at present, and comprises a base, a detection cylinder is arranged right above the base, a stirring mechanism is arranged between the base and the detection cylinder, and the stirring mechanism is connected with the detection cylinder. The stirring mechanism comprises an L-shaped frame fixed at the top of the base; according to the device, through the cooperation between the motor and the transmission shaft as well as between the conveyor belt and the stirring shaft, the stirring rod rotates to stir a solution in the detection cylinder, through the cooperation between the bevel gear I and the bevel gear II as well as the driven shaft, the disc rotates conveniently, and through the cooperation between the driving rod and the sleeve plate as well as the cooperation between the U-shaped round rod and the U-shaped plate, the detection efficiency is improved. The detection barrel can continuously move up and down conveniently, then a solution in the detection barrel can continuously move, and meanwhile, the position of a stirring rod in the detection barrel is changed, so that a 5-aminolevulinic acid sample and a reagent can be uniformly mixed conveniently.

Description

Technical Field

[0001] The utility model belongs to the technical field of content detection, and specifically is a device for accurately detecting the content of 5-aminolevulinic acid. Background Art

[0002] 5-Aminolevulinic acid (5-ALA) is a chemical. It is the common precursor for the biosynthesis of all porphyrin compounds. This compound is widely present in bacteria, fungi, animals, plants and other living organisms. It is a non-protein amino acid. In plants, 5-ALA is naturally present and is necessary for plant life activities. It is a metabolically active physiologically active substance. It has the characteristics of no toxic side effects, easy degradation and no residue. The content of 5-aminolevulinic acid needs to be tested during the production process.

[0003] At present, when using the detection device for the content of 5-aminolevulinic acid, the 5-aminolevulinic acid sample is usually dissolved in water, and an appropriate amount of reagent is added to convert it into a corresponding compound. Then, the absorbance of the sample is measured using a spectrophotometer, and the concentration of 5-aminolevulinic acid in the sample is determined according to the standard curve. At present, the 5-aminolevulinic acid sample, water and reagent are only stirred by a stirring rod. Since the position of the stirring rod is fixed, the solution is unevenly mixed. Utility Model Content

[0004] In view of the above situation, in order to overcome the defects of the prior art, the utility model provides a precise detection device for the content of 5-aminolevulinic acid, which effectively solves the problem of uneven mixing of 5-aminolevulinic acid samples and reagents.

[0005] To achieve the above object, the utility model provides the following technical solution: a precise detection device for 5-aminolevulinic acid content, comprising a base, a detection cylinder is provided just above the base, and a stirring mechanism is installed between the base and the detection cylinder;

[0006] The stirring mechanism includes an L-shaped frame fixed to the top of the base, the inner top wall of the L-shaped frame is rotatably connected to a stirring shaft, the bottom end of the stirring shaft extends into the detection cylinder, the outer side of the stirring shaft is fixedly connected at equal angles to stirring rods located in the detection cylinder, two U-shaped round rods are symmetrically fixedly connected to the bottom of the detection cylinder, and two U-shaped plates are symmetrically fixedly connected to the top of the base, the two U-shaped round rods respectively penetrate the two U-shaped plates, and the two U-shaped round rods are movably connected to the two U-shaped plates respectively.

[0007] Preferably, a motor is fixedly mounted on the inner top wall of the L-shaped frame, a transmission shaft is fixedly mounted on the motor, the transmission shaft is located outside the detection cylinder, transmission wheels are fixedly mounted on the outsides of the transmission shaft and the stirring shaft, and a conveyor belt is connected between the two transmission wheels.

[0008] Preferably, the inner side wall of the L-shaped frame is rotatably connected to a driven shaft, a disc is fixedly installed on one end of the driven shaft away from the L-shaped frame, the outer sides of the two U-shaped round rods are fixedly sleeved with the same sleeve plate, the sleeve plate is located directly above the disc, the end of the disc away from the driven shaft is rotatably connected to a driving rod, and the end of the driving rod away from the disc is rotatably connected to the sleeve plate.

[0009] Preferably, a bevel gear 2 is fixedly mounted on the outer side of the driven shaft, a bevel gear 1 is fixedly mounted on the bottom end of the transmission shaft, and the bevel gear 1 is meshingly connected with the bevel gear 2.

[0010] Preferably, an L-shaped plate is fixedly installed between the inner side wall of the L-shaped frame and the top of the base, and the driven shaft and the transmission shaft both pass through the L-shaped plate and are rotatably connected to the L-shaped plate.

[0011] Preferably, a top ring is fixedly installed on the top of the detection cylinder, a through hole is provided on the top of the detection cylinder, the inner diameter of the through hole is equal to the inner diameter of the top ring, the stirring shaft passes through the top ring and the through hole, and the outer diameter of the stirring shaft is smaller than the inner diameter of the top ring, an annular groove is provided on the inner side of the top ring, and balls are installed at equal angles in the annular groove and are in contact with the outer wall of the stirring shaft.

[0012] Compared with the prior art, the beneficial effects of the utility model are:

[0013] (1) The utility model facilitates the rotation of the stirring rod to stir the solution inside the detection tube through the cooperation between the motor and the transmission shaft and the conveyor belt and the stirring shaft, and facilitates the rotation of the disc through the cooperation between the bevel gear 1 and the bevel gear 2 and the driven shaft, and facilitates the continuous up and down movement of the detection tube through the cooperation between the driving rod and the sleeve plate and the U-shaped round rod and the U-shaped plate, thereby enabling the solution in the detection tube to continuously move, and at the same time changing the position of the stirring rod in the detection tube, thereby facilitating the uniform mixing of the 5-aminolevulinic acid sample and the reagent;

[0014] (2) The new type of device is provided with a top ring on the top of the detection cylinder, and an annular groove is provided in the top ring. A plurality of balls are provided in the annular groove to abut against the outer wall of the stirring shaft, thereby limiting the stirring shaft, thereby ensuring the stability of the stirring shaft during rotation and reducing the friction force on the detection cylinder when it moves up and down. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] The accompanying drawings are used to provide a further understanding of the present invention and constitute a part of the specification. They are used together with the embodiments of the present invention to explain the present invention and do not constitute a limitation to the present invention.

[0016] In the attached picture:

[0017] Figure 1 This is a schematic diagram of the structure of a precise detection device for 5-aminolevulinic acid content of the utility model;

[0018] Figure 2 This is a schematic diagram of the structure of the stirring mechanism of the utility model;

[0019] Figure 3 This is a schematic diagram of the top ring structure of the utility model;

[0020] In the figure: 1. base; 2. stirring mechanism; 201. L-shaped frame; 202. transmission shaft; 203. bevel gear one; 204. bevel gear two; 205. driven shaft; 206. disc; 207. driving rod; 208. U-shaped round rod; 209. U-shaped plate; 2010. stirring rod; 2011. stirring shaft; 2012. top ring; 2013. transmission wheel; 2014. conveyor belt; 2015. motor; 2016. ball bearing; 2017. annular groove; 2018. sleeve plate; 2019. L-shaped plate; 3. detection cylinder. DETAILED DESCRIPTION

[0021] The technical solutions in the embodiments of the utility model will be clearly and completely described below in conjunction with the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all of the embodiments; based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the utility model.

[0022] Embodiment 1, by Figure 1 The utility model comprises a base 1 , a detection cylinder 3 is arranged just above the base 1 , and a stirring mechanism 2 is installed between the base 1 and the detection cylinder 3 .

[0023] Specifically, by Figure 2It is given that the stirring mechanism 2 includes an L-shaped frame 201 fixed to the top of the base 1, the inner top wall of the L-shaped frame 201 is rotatably connected with a stirring shaft 2011, the bottom end of the stirring shaft 2011 extends into the detection cylinder 3, the outer side of the stirring shaft 2011 is fixedly connected at equal angles with stirring rods 2010 both located in the detection cylinder 3, the bottom of the detection cylinder 3 is symmetrically fixedly connected with two U-shaped round rods 208, the top of the base 1 is symmetrically fixedly connected with two U-shaped plates 209, the two U-shaped round rods 208 respectively penetrate the two U-shaped plates 209, and the two U-shaped round rods 208 are respectively movably connected to the two U-shaped plates 209, the inner top wall of the L-shaped frame 201 is fixedly installed with a motor 2015, the motor 2015 is fixedly installed with a transmission shaft 202, the transmission shaft 202 is located on the outer side of the detection cylinder 3, the transmission shaft 202 and the outer side of the stirring shaft 2011 are fixedly installed with transmission wheels 2013, between the two transmission wheels 2013 The transmission is connected with a conveyor belt 2014, the inner side wall of the L-shaped frame 201 is rotatably connected with a driven shaft 205, and a disc 206 is fixedly installed on the end of the driven shaft 205 away from the L-shaped frame 201, and the outer sides of the two U-shaped round rods 208 are fixedly sleeved with the same sleeve plate 2018, and the sleeve plate 2018 is located directly above the disc 206, and the end of the disc 206 away from the driven shaft 205 is rotatably connected with a driving rod 207, and the driving rod 207 is away from the disc 20 One end of the L-shaped frame 201 is rotatably connected to the sleeve plate 2018, a bevel gear 204 is fixedly installed on the outer side of the driven shaft 205, a bevel gear 1 203 is fixedly installed on the bottom end of the transmission shaft 202, and the bevel gear 1 203 is meshed and connected with the bevel gear 204. An L-shaped plate 2019 is fixedly installed between the inner side wall of the L-shaped frame 201 and the top of the base 1, and the driven shaft 205 and the transmission shaft 202 both penetrate the L-shaped plate 2019 and are rotatably connected to the L-shaped plate 2019;

[0024] In the use state, the motor 2015 is first started to drive the transmission shaft 202 to rotate, and the stirring shaft 2011 is driven to rotate through the conveyor belt 2014. At this time, the stirring rod 2010 rotates to stir the solution in the detection tube 3, and the bottom end of the transmission shaft 202 is provided with a bevel gear 1 203. Since the bevel gear 1 203 is meshed and connected with the bevel gear 2 204, it drives the rotation of the driven shaft 205, and the disk 206 rotates at the same time, and then drives the sleeve plate 2018 to move through the driving rod 207. Since the two U-shaped round rods 208 are movably connected with the two U-shaped plates 209 respectively, the detection tube 3 is driven to move up and down continuously, and the solution in the detection tube 3 is fully moved. At the same time, the position of the stirring rod 2010 in the detection tube 3 is changed, and finally the liquid in the detection tube 3 is fully stirred, and the 5-aminolevulinic acid sample and the reagent are evenly mixed.

[0025] Specifically, by Figure 3It is given that a top ring 2012 is fixedly installed on the top of the detection cylinder 3, a through hole is provided on the top of the detection cylinder 3, the inner diameter value of the through hole is equal to the inner diameter value of the top ring 2012, the stirring shaft 2011 passes through the top ring 2012 and the through hole, and the outer diameter value of the stirring shaft 2011 is smaller than the inner diameter value of the top ring 2012, an annular groove 2017 is provided on the inner side of the top ring 2012, and balls 2016 are installed at equal angles in the annular groove 2017 and are in contact with the outer wall of the stirring shaft 2011;

[0026] When in use, firstly, a top ring 2012 is fixed on the top of the detection cylinder 3, and an annular groove 2017 is provided on the inner side of the top ring 2012, and then a plurality of balls 2016 are installed in the annular groove 2017, so that each ball 2016 abuts against the outer side of the stirring shaft 2011, and finally, the friction force on which the detection cylinder 3 is subjected when moving up and down is reduced, while ensuring the stability of the stirring shaft 2011 when rotating.

Claims

1. A device for accurately detecting the content of 5-aminolevulinic acid, comprising a base (1), characterized in that: A detection cylinder (3) is provided directly above the base (1), and a stirring mechanism (2) is installed between the base (1) and the detection cylinder (3); The stirring mechanism (2) comprises an L-shaped frame (201) fixed to the top of the base (1); the inner top wall of the L-shaped frame (201) is rotatably connected to a stirring shaft (2011); the bottom end of the stirring shaft (2011) extends into the detection cylinder (3); the outer side of the stirring shaft (2011) is fixedly connected at equal angles to stirring rods (2010) both located in the detection cylinder (3); the bottom of the detection cylinder (3) is symmetrically fixedly connected to two U-shaped round rods (208); the top of the base (1) is symmetrically fixedly connected to two U-shaped plates (209); the two U-shaped round rods (208) respectively penetrate the two U-shaped plates (209), and the two U-shaped round rods (208) are respectively movably connected to the two U-shaped plates (209).

2. The device for accurately detecting the content of 5-aminolevulinic acid according to claim 1, characterized in that: A motor (2015) is fixedly mounted on the inner top wall of the L-shaped frame (201), a transmission shaft (202) is fixedly mounted on the motor (2015), the transmission shaft (202) is located outside the detection cylinder (3), transmission wheels (2013) are fixedly mounted on the outsides of the transmission shaft (202) and the stirring shaft (2011), and a conveyor belt (2014) is connected between the two transmission wheels (2013).

3. The device for accurately detecting the content of 5-aminolevulinic acid according to claim 1, characterized in that: The inner side wall of the L-shaped frame (201) is rotatably connected to a driven shaft (205); a disc (206) is fixedly installed on one end of the driven shaft (205) away from the L-shaped frame (201); the outer sides of the two U-shaped round rods (208) are fixedly sleeved with a same sleeve plate (2018); the sleeve plate (2018) is located directly above the disc (206); one end of the disc (206) away from the driven shaft (205) is rotatably connected to a driving rod (207); and one end of the driving rod (207) away from the disc (206) is rotatably connected to the sleeve plate (2018).

4. The device for accurately detecting the content of 5-aminolevulinic acid according to claim 3, characterized in that: A second bevel gear (204) is fixedly mounted on the outer side of the driven shaft (205), and a first bevel gear (203) is fixedly mounted on the bottom end of the transmission shaft (202), and the first bevel gear (203) is meshingly connected with the second bevel gear (204).

5. The device for accurately detecting the content of 5-aminolevulinic acid according to claim 1, characterized in that: An L-shaped plate (2019) is fixedly installed between the inner side wall of the L-shaped frame (201) and the top of the base (1), and the driven shaft (205) and the transmission shaft (202) both penetrate the L-shaped plate (2019) and are rotatably connected to the L-shaped plate (2019).

6. The device for accurately detecting the content of 5-aminolevulinic acid according to claim 1, characterized in that: A top ring (2012) is fixedly mounted on the top of the detection cylinder (3); a through hole is arranged on the top of the detection cylinder (3); the inner diameter of the through hole is equal to the inner diameter of the top ring (2012); the stirring shaft (2011) passes through the top ring (2012) and the through hole; the outer diameter of the stirring shaft (2011) is smaller than the inner diameter of the top ring (2012); an annular groove (2017) is arranged on the inner side of the top ring (2012); and balls (2016) are mounted at equal angles in the annular groove (2017) and are in contact with the outer wall of the stirring shaft (2011).

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