Eight-color fluorescence detection kit for 44 autosomal loci

Abstract

The utility model relates to the field of fluorescence detection kits, in particular to an eight-color fluorescence detection kit for 44 autosomal gene loci, which comprises a kit body, a kit cover, a gene paper placing seat and a driving lever, the kit cover covers the top of the kit body, the gene paper placing seat can be transversely and slidably mounted in the kit body, the driving lever is positioned on the outer side of the kit body, and the gene paper placing seat can be transversely and slidably mounted in the kit body. According to the eight-color fluorescence detection kit for the 44 autosomal gene loci, the gene paper placing seat can horizontally slide in the kit body, so that the six-color fluorescence detection platform can only detect six stations originally, and the six-station detection can be carried out now, so that the detection efficiency is greatly improved, and the detection cost is reduced. According to the detection kit, multiple kits do not need to be combined for use, manpower and financial resources are saved, more time is also saved, the gene paper placing seat can be prevented from shaking in the kit body when the detection kit is switched in position and transported, and good operation of the kit in use is ensured.

Description

Technical Field

[0001] The utility model relates to the field of fluorescence detection kits, in particular to an eight-color fluorescence detection kit for 44 autosomal gene loci. Background Art

[0002] The VersaPlex 27PY System produced by Promega in the United States, and the domestic base point recognition 25A, microreader 28A ID, Sino-German Meilian EX25, and Haiershi PanGlobal all cover the new CODIS loci recommended by the US FBI on January 1, 2017, and also include the 18 common autosomes in the National DNA Database of the Ministry of Public Security of China. In addition, Wuxi Sino-German Meilian Biotechnology Co., Ltd., Suzhou Microreader Gene Technology Co., Ltd., and base point recognition technology (Beijing) Co., Ltd. have successively launched commercial paternity test supplementary kits such as AGCU 21+1, MicroreaderTM 23sp ID system, and Goldeneye® 18NC.

[0003] However, due to the limitations of the six-color fluorescence detection platform, there are almost no complete test kits that can simultaneously detect core loci and supplementary loci. If you want to detect simultaneously, you must use multiple test kits in combination, which not only increases manpower and financial resources, but also takes more time. When performing chromosome staining tests, practical composite amplification kits are required. Therefore, it is necessary to develop an eight-color fluorescence detection kit for 44 autosomal loci to solve the above problems. Utility Model Content

[0004] The utility model aims to provide an eight-color fluorescence detection kit for 44 autosomal gene loci.

[0005] To achieve this purpose, the utility model adopts the following technical solutions:

[0006] An eight-color fluorescence detection kit for 44 autosomal gene loci is provided, comprising a box body, a box cover, a gene paper placement seat and a lever. The box cover is closed on the top of the box body, the gene paper placement seat can be installed in the box body in a transversely slidable manner, the lever is located on the outside of the box body, the lever passes through a side wall of the box body and is fixedly connected to the gene paper placement seat, a slide groove for the lever to pass through and slide horizontally is provided on the box body, eight detection gene papers are arranged on the top of the gene paper placement seat, and the eight detection gene papers are horizontally distributed along the transverse direction of the gene paper placement seat.

[0007] Furthermore, six liquid-passing grooves are provided on the top of the box cover, and the distance between every two adjacent liquid-passing grooves is the same as the distance between every two adjacent detection gene papers.

[0008] Furthermore, a guide slide is provided at the inner bottom of the box body, and two slide plates are fixedly provided at the bottom of the gene paper placement seat, and the inner sides of the two slide plates are fitted with the two sides of the guide slide.

[0009] Furthermore, the cover plate is rotatably mounted on the box cover, and six baffles are arranged on the cover plate. When the cover plate is closed on the box cover, five baffles are clamped in the liquid flow tank.

[0010] Furthermore, two clamping plates are fixedly arranged at one end of the baffle bar away from the hinge, and the shifting rod is clamped at the inner sides of the two clamping plates.

[0011] Furthermore, a square concave hole is provided at the bottom of the box body, and a plurality of reinforcing rods are provided at the top of the square concave hole.

[0012] The beneficial effects of the utility model are as follows: the eight-color fluorescence detection kit for 44 autosomal gene loci can slide horizontally in the box body through the gene paper placement seat, so that the six-color fluorescence detection platform, which was originally only able to detect six stations, can now be changed to six-station detection. There is no need to use multiple kits in combination, which saves manpower and financial resources and more time. In addition, the detection kit can avoid the shaking of the gene paper placement seat in the box body when switching positions and transporting, thereby ensuring the good operation of the kit when it is used. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] In order to more clearly illustrate the technical solution of the embodiment of the utility model, the following is a brief introduction to the drawings required for use in the embodiment of the utility model.

[0014] Figure 1 It is a three-dimensional structural schematic diagram of the utility model;

[0015] Figure 2 It is a partial top view of the utility model;

[0016] Figure 3 It is a partial three-dimensional structural schematic diagram of the utility model;

[0017] Figure 4 It is a schematic diagram of the partial three-dimensional structure of the utility model;

[0018] Figure 5 for Figure 1 A schematic diagram of a three-dimensional structure from another perspective;

[0019] Figure 6 for Figure 1 Schematic diagram of the three-dimensional structure at the bottom;

[0020] In the figure: 1, box body; 1a, slide groove; 1b, guide slide bar; 1c, square concave hole; 2, box cover; 2a, liquid flow trough; 3, gene paper placement seat; 3a, detection gene paper; 3b, slide plate; 4, lever; 5, cover plate; 5a, baffle bar; 5b, card plate. DETAILED DESCRIPTION

[0021] The technical solution of the utility model is further explained below with reference to the accompanying drawings and through specific implementation methods.

[0022] Among them, the drawings are only used for illustrative purposes and represent only schematic diagrams rather than actual pictures, and should not be understood as limitations on this patent; in order to better illustrate the embodiments of the utility model, some parts of the drawings will be omitted, enlarged or reduced, and do not represent the size of the actual product.

[0023] Reference Figures 1 to 6 The eight-color fluorescence detection kit for 44 autosomal loci shown comprises a box body 1, a box cover 2, a gene paper placement seat 3 and a lever 4. The box cover 2 covers the top of the box body 1, the gene paper placement seat 3 can be installed in the box body 1 in a lateral sliding manner, the lever 4 is located on the outside of the box body 1, the lever 4 passes through a side wall of the box body 1 and is fixedly connected to the gene paper placement seat 3, the box body 1 is provided with a slide slot 1a for the lever 4 to pass through and slide horizontally, and eight detection gene papers 3a are arranged on the top of the gene paper placement seat 3, and the eight detection gene papers 3a are horizontally distributed along the lateral direction of the gene paper placement seat 3. When the test is required, the kit is first placed on the six-color fluorescence detection platform, and then the first test is started. After the first test is completed, the tester pushes the lever 4 horizontally, so that the lever 4 drives the gene paper placement seat 3 to slide horizontally, so that the remaining two detection gene papers 3a that have not been detected before can be moved into the detection range, and then the remaining two detection gene papers 3a are detected by the six-color fluorescence detection platform.

[0024] Six liquid-passing grooves 2a are provided on the top of the box cover 2, and the distance between each two adjacent liquid-passing grooves 2a is the same as the distance between each two adjacent detection gene papers 3a. The detection liquid dripped from the six-color fluorescence detection platform can pass through the liquid-passing grooves 2a and drip onto the detection gene paper 3a, and the test can be performed without the tester opening the box cover 2. That is, the displacement of the gene paper placement seat 3 caused by the vibration of the box body 1 when the box cover 2 is opened will not occur.

[0025] A guide bar 1b is provided at the inner bottom of the box body 1, and two slide plates 3b are fixedly provided at the bottom of the gene paper placement seat 3, and the inner sides of the two slide plates 3b are in contact with the two sides of the guide bar 1b. By pushing the gene paper placement seat 3 horizontally, the slide plates 3b can slide laterally along the guide bar 1b, preventing the gene paper placement seat 3 from rotating during the pushing process.

[0026] It can be imagined that the guide slide 1b can be arranged in two rows, and four slides 3b are arranged at the bottom of the box cover 2. Every two slides 3b are slidably connected to a guide slide 1b, so that the gene paper placement seat 3 can move more stably during the process of being pushed.

[0027] The cover plate 5 is rotatably mounted on the box cover 2. Six baffles 5a are provided on the cover plate 5. When the cover plate 5 is covered on the box cover 2, the five baffles 5a are locked in the liquid passage trough 2a. The liquid passage trough 2a is covered by the cover plate 5 to prevent contamination during transportation of the reagent kit. A rotating plate is provided on the cover plate 5, and a rotating seat connected to the rotating plate is provided on the box cover 2. The rotating shaft of the rotating seat is plugged into the rotating plate, so that the cover plate 5 can be rotatably mounted on the box cover 2.

[0028] Two clamping plates 5b are fixedly arranged at one end of the baffle 5a away from the hinge, and the lever 4 is clamped on the inner side of the two clamping plates 5b. When the cover plate 5 is closed on the box cover 2, the inner sides of the two clamping plates 5b will be clamped with the two sides of the lever 4, so that the lever 4 cannot move horizontally, that is, the gene paper placement seat 3 is positioned to prevent the gene paper placement seat 3 from sliding horizontally in the box body 1 during transportation.

[0029] A square recessed hole 1c is provided at the bottom of the box body 1, and a plurality of reinforcing rods are provided at the top of the square recessed hole 1c. By providing the square recessed hole 1c, the box body 1 can be clamped on the platform of the six-color fluorescence detection platform, and when the tester pushes the lever 4 to move, the box body 1 does not need to be moved sideways.

[0030] The above are only preferred embodiments of the present invention. It should be pointed out that, for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the technical principles of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. Eight-color fluorescence detection kit for 44 autosomal loci, characterized in that: The invention comprises a box body (1), a box cover (2), a gene paper placement seat (3) and a lever (4), wherein the box cover (2) covers the top of the box body (1), the gene paper placement seat (3) can be installed in the box body (1) in a transversely slidable manner, the lever (4) is located outside the box body (1), the lever (4) passes through a side wall of the box body (1) and is fixedly connected to the gene paper placement seat (3), the box body (1) is provided with a slide groove (1a) for the lever (4) to pass through and slide horizontally, and eight detection gene papers (3a) are arranged on the top of the gene paper placement seat (3), and the eight detection gene papers (3a) are horizontally distributed along the transverse direction of the gene paper placement seat (3).

2. The eight-color fluorescence detection kit for 44 autosomal loci according to claim 1, characterized in that: Six liquid-passing grooves (2a) are provided on the top of the box cover (2), and the distance between every two adjacent liquid-passing grooves (2a) is the same as the distance between every two adjacent detection gene papers (3a).

3. The eight-color fluorescence detection kit for 44 autosomal loci according to claim 2, characterized in that: A guide slide (1b) is provided at the inner bottom of the box body (1), and two slide plates (3b) are fixedly provided at the bottom of the gene paper placement seat (3), and the inner sides of the two slide plates (3b) are in contact with the two sides of the guide slide (1b).

4. The eight-color fluorescence detection kit for 44 autosomal loci according to claim 2, characterized in that: The cover plate (5) is rotatably mounted on the box cover (2). Six baffles (5a) are arranged on the cover plate (5). When the cover plate (5) is closed on the box cover (2), the five baffles (5a) are clamped in the liquid passage tank (2a).

5. The eight-color fluorescence detection kit for 44 autosomal loci according to claim 4, characterized in that: Two clamping plates (5b) are fixedly arranged at one end of the blocking bar (5a) away from the hinged portion, and the shifting rod (4) is clamped on the inner sides of the two clamping plates (5b).

6. The eight-color fluorescence detection kit for 44 autosomal loci according to claim 1, characterized in that: A square recessed hole (1c) is provided at the bottom of the box body (1), and a plurality of reinforcing rods are provided at the top of the square recessed hole (1c).

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