Low-temperature preservation device for mouse heart tissue

Abstract

The utility model relates to the technical field of mouse heart tissue cryopreservation, in particular to a mouse heart tissue cryopreservation device. The mouse heart tissue low-temperature preservation device comprises a preservation box, a handle, a plurality of isolation frames, placing plates, a pull rod block, a first magnetic block and a second magnetic block, the handle is fixedly connected to the top of the preservation box, the multiple isolation frames are arranged on the preservation box in a sliding mode, the placing plates are fixedly connected to the interiors of the isolation frames, and the pull rod block is arranged on the first magnetic block. A pull rod block is fixedly connected to the front side of the isolation frame, a plurality of first magnetic blocks are arranged in the storage box, two second magnetic blocks are arranged in the isolation frame, and the first magnetic blocks are attracted by the second magnetic blocks. The mouse heart tissues are placed on the six isolation frames, so that a plurality of mouse heart tissues are stored in the same storage box, the mouse heart tissues are conveniently compared in the experiment process, independent storage of the mouse heart tissues is realized, and the risks of cross contamination and injury are reduced.

Description

TECHNICAL FIELD

[0001] The utility model relates to mouse heart tissue cryopreservation technical field especially, relate to a mouse heart tissue cryopreservation device. BACKGROUND

[0002] In biomedical research, mouse heart tissue is often used as a research model due to its similarity to human heart tissue. To ensure the accuracy and reliability of experimental results, mouse heart tissue needs to be properly preserved after collection, especially when long-term storage or cross-period comparison analysis is required.

[0003] Cryopreservation, as a widely recognized technical means, slows down or stops biochemical reactions by reducing temperature to slow down cellular metabolic activity, thereby extending the survival time of heart tissue. However, during actual cryopreservation, the preservation container can only hold one sample at a time, limiting direct comparison of multiple mouse heart tissues during experiments. On the other hand, when attempting to store multiple mouse heart tissues in the same preservation container, the lack of effective isolation measures may result in physical contact or chemical reactions between different samples, leading to cross-contamination or damage.

[0004] Therefore, there is a need for a cryopreservation device for comparing mouse heart tissues. SUMMARY

[0005] To overcome the shortcomings of existing technology, which can only hold one sample at a time in the preservation container, limiting direct comparison of multiple mouse heart tissues during experiments, and on the other hand, when attempting to store multiple mouse heart tissues in the same preservation container, the lack of effective isolation measures may result in physical contact or chemical reactions between different samples, leading to cross-contamination or damage, the utility model provides a cryopreservation device for comparing mouse heart tissues.

[0006] The technical solution is: a mouse heart tissue cryopreservation device, including the preservation box, handle, isolation frame, placement plate, pull rod block, first magnetic block, second magnetic block, controller and low temperature pipe, the preservation box top fixedly connected with handle, the preservation box is slidably provided with a plurality of isolation frames, the isolation frame inside fixedly connected with placement plate, the isolation frame front side fixedly connected with pull rod block, the preservation box inside is provided with a plurality of first magnetic blocks, the isolation frame inside is provided with two second magnetic blocks, and the second magnetic block is adsorbed to the first magnetic block, the preservation box left and right sides are all installed with a plurality of controllers, and the controller is connected with low temperature pipe, and the low temperature pipe is located above the isolation frame.

[0007] Further, the mobile plate, guide rod, spring and blocking plate are further included, a plurality of guide rods are fixedly connected to the left and right sides of the storage box, the mobile plate is slidably arranged on the guide rod, the spring is sleeved on the guide rod, and the two ends of the spring are connected with the storage box and the mobile plate respectively, the blocking plate is fixedly connected to the front side of the mobile plate and can contact the isolation frame.

[0008] Further, the support block, UV lamp and switch are further included, a plurality of support blocks are arranged in the storage box, the UV lamp is arranged on each support block, a plurality of switches are installed on the rear side of the storage box, and the switch is electrically connected with the UV lamp.

[0009] Further, the pull plate is further included, and the pull plate is fixedly connected to the rear side of the blocking plate.

[0010] Further, the stable plate is further included, and the stable plate is fixedly connected to the bottom of the storage box.

[0011] Further, the anti-skid sleeve is further included, and the anti-skid sleeve is sleeved on the handle.

[0012] Compared with the prior art, the mouse heart tissue low-temperature storage device has the following beneficial effects: 1. By placing six isolation frames on the mouse heart tissue, multiple mouse heart tissues can be stored in the same storage box, which facilitates comparison of the mouse heart tissues during the experiment, and also realizes separate storage of the mouse heart tissues, thereby reducing the risk of cross contamination and damage.

[0013] 2. The spring restores the original state to push the mobile plate to move inward and reset, so that the blocking plate repositions the isolation frame, thereby further fixing the isolation frame and avoiding movement of the isolation frame to affect the low-temperature storage effect.

[0014] 3. After the UV lamp is turned on, the ultraviolet rays are used to destroy the microorganisms on the isolation frame and the placement plate, thereby achieving the purpose of sterilization and disinfection and creating favorable conditions for subsequent low-temperature storage. BRIEF DESCRIPTION OF DRAWINGS

[0015] Figure 1 It is a three-dimensional structure schematic view of the utility model.

[0016] Figure 2 It is a three-dimensional structure sectional view of the storage box, handle and isolation frame and other parts of the utility model.

[0017] Figure 3 It is a three-dimensional structure sectional view of the first magnetic block, second magnetic block and low-temperature pipe and other parts of the utility model.

[0018] Figure 4 It is a three-dimensional structure sectional view of the mobile plate, spring and blocking plate and other parts of the utility model.

[0019] Figure 5 The utility model discloses support block, UV lamp and switcher etc. Parts of solid structure sectional view.

[0020] Part name and serial number in drawing: 1, keep box, 2, handle, 3, isolation frame, 4, placing plate, 5, pull rod block, 6, first magnetic block, 7, second magnetic block, 8, controller, 9, low temperature pipe, 10, moving plate, 11, guide rod, 12, spring, 13, pull plate, 14, baffle, 15, support block, 16, UV lamp, 17, switcher, 18, stabilizing plate, 19, antiskid sleeve. DETAILED DESCRIPTION

[0021] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model and not all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by the person skilled in the art without creative labor fall within the protection scope of the utility model.

[0022] Embodiment 1: a mouse heart tissue cryopreservation device, please refer to Figures 1-5 , including keep box 1, handle 2, isolation frame 3, placing plate 4, pull rod block 5, first magnetic block 6, second magnetic block 7, controller 8 and low temperature pipe 9, keep box 1 top fixedly connected with handle 2, keep box 1 on slide type is provided with six isolation frames 3, and isolation frame 3 inside is fixedly connected with placing plate 4, and the middle part of placing plate 4 is slightly concave downward, and it is convenient to quickly place mouse heart tissue on the center position of placing plate 4, and isolation frame 3 front side is fixedly connected with pull rod block 5, and keep box 1 inside is provided with a plurality of first magnetic blocks 6, and isolation frame 3 inside is provided with two second magnetic blocks 7, and second magnetic block 7 adsorbs first magnetic block 6, and keep box 1 left and right sides are all installed with six controllers 8, and the model of controller 8 is OMRONE5CC series, and controller 8 is connected with low temperature pipe 9, and low temperature pipe 9 is located above isolation frame 3, and keep box 1 bottom is fixedly connected with stabilizing plate 18, and stabilizing plate 18 is used to increase the stability of keep box 1 whole, and handle 2 is sleeved with antiskid sleeve 19, and antiskid sleeve 19 increases the friction between hand and handle 2, to avoid the hand from slipping when moving keep box 1.

[0023] When it is necessary to store mouse heart tissues at low temperature, first hold the pull rod block 5 and pull forward to separate the isolation frame 3 from the storage box 1, at this time, the magnetic force between the second magnetic block 7 and the first magnetic block 6 disappears, and then the isolation frame 3 is taken out, then the mouse heart tissues are placed on the center position of the placement plate 4, after the placement is completed, the isolation frame 3 is moved to the front side of the storage box 1, and it is ensured that it is aligned with the placement groove on the storage box 1, then the isolation frame 3 is pushed backward and placed into the storage box 1, at this time, the second magnetic block 7 will re-adsorb the first magnetic block 6 to fix the isolation frame 3 on the storage box 1, repeat the above operation to place six isolation frames 3 on mouse heart tissues, so as to store multiple mouse heart tissues in the same storage box 1, which is convenient for comparing mouse heart tissues in the experiment, and also realizes the separate storage of mouse heart tissues, thereby reducing the risk of cross contamination and damage, when all mouse heart tissues are placed, the controller 8 is started to open the low-temperature pipe 9, and the temperature of the low-temperature pipe 9 is adjusted to ensure that it is in the best temperature range, so as to provide the best protection effect for the mouse heart tissues and ensure the survival rate of the mouse heart tissues under low-temperature conditions.

[0024] Example 2: Based on example 1, please refer to Figure 1 and Figure 4 Three guide rods 11 are fixedly connected to the left and right sides of the storage box 1, a moving plate 10 is slidably arranged on the guide rods 11, springs 12 are sleeved on the guide rods 11, and the two ends of the springs 12 are connected with the storage box 1 and the moving plate 10 respectively, a blocking plate 14 is fixedly connected to the front side of the moving plate 10, the blocking plate 14 can contact the isolation frame 3, and a pull plate 13 is fixedly connected to the rear side of the blocking plate 14, and the position of the blocking plate 14 is adjusted by pulling the pull plate 13.

[0025] When it is necessary to take out the isolation frame 3, first pull the blocking plate 14 outward to release the limitation of the isolation frame 3, in this process, the moving plate 10 moves outward and compresses the spring 12, then the isolation frame 3 is taken out, the mouse heart tissues are placed on the placement plate 4, after the placement is completed, the isolation frame 3 is placed back on the storage box 1, at this time, the blocking plate 14 is released, the spring 12 returns to its original state and pushes the moving plate 10 to move inward to reset, so that the blocking plate 14 limits the isolation frame 3 again, thereby further fixing the isolation frame 3 to avoid movement of the isolation frame 3 and affect the low-temperature storage effect.

[0026] Please refer to Figure 5 Six groups of support blocks 15 are arranged in the storage box 1, a UV lamp 16 is arranged on each group of support blocks 15, and six switch devices 17 are installed on the rear side of the storage box 1 and are electrically connected with the UV lamps 16.

[0027] After the mouse heart tissue is taken out, the switch device 17 is pressed to turn on the UV lamp 16, the UV lamp 16 is lighted, the microorganisms on the isolation frame 3 and the placement plate 4 are destroyed by using ultraviolet rays, so that the purpose of sterilization and disinfection is achieved, and favorable conditions are created for subsequent low-temperature preservation.

[0028] Although the embodiments of the utility model have been shown and described, it can be understood by those skilled in the art that various changes, modifications, replacements and variations can be made to these embodiments without departing from the principles and spirits of the utility model, and the scope of the utility model is defined by the appended claims and their equivalents.

Claims

1. A mouse heart tissue cryopreservation device, characterized by, Including the preservation box (1), handle (2), isolation frame (3), placement plate (4), pull rod block (5), first magnetic block (6), second magnetic block (7), controller (8) and low temperature pipe (9), the preservation box (1) top fixedly connected with handle (2), the preservation box (1) on slide type multiple isolation frame (3) are set up, isolation frame (3) inside fixedly connected with placement plate (4), isolation frame (3) front side fixedly connected with pull rod block (5), the preservation box (1) inside multiple first magnetic block (6) are set up, the isolation frame (3) inside two second magnetic block (7) are set up, second magnetic block (7) adsorb first magnetic block (6), the preservation box (1) left and right sides are installed with multiple controller (8), the controller (8) is connected with low temperature pipe (9), and low temperature pipe (9) is located above isolation frame (3).

2. The mouse heart tissue cryopreservation device according to claim 1, wherein Still including mobile plate (10), guide rod (11), spring (12) and baffle (14), the preservation box (1) left and right sides are fixedly connected with multiple guide rods (11), and the guide rod (11) is set up with mobile plate (10) on the slide type, and the guide rod (11) is set with spring (12) on the sleeve, and the spring (12) both ends are connected with the preservation box (1) and mobile plate (10), and the mobile plate (10) front side fixedly connected with baffle (14), and baffle (14) can be contacted with isolation frame (3).

3. The mouse heart tissue cryopreservation device according to claim 2, wherein Still including support block (15), UV lamp (16) and switcher (17), the preservation box (1) inside multiple groups of support block (15) are set up, and each group of support block (15) is set up with UV lamp (16), and the preservation box (1) rear side is installed with multiple switcher (17), and switcher (17) is electrically connected with UV lamp (16).

4. The mouse heart tissue cryopreservation device according to claim 3, wherein Still including pull plate (13), and the baffle (14) rear side fixedly connected with pull plate (13).

5. The mouse heart tissue cryopreservation device according to claim 4, wherein Still including stabilizing plate (18), the preservation box (1) bottom fixedly connected with stabilizing plate (18).

6. The mouse heart tissue cryopreservation device according to claim 5, wherein Still including antiskid sleeve (19), and handle (2) is set with antiskid sleeve (19) on the sleeve.

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