1 results about "3c protease" patented technology

This invention belongs to the field of biomedical technology, specifically relating to lactoferrin peptides and the application of lactoferrin in the preparation of inhibitors of 3C protease. The lactoferrin peptides of this invention contain the amino acid sequence shown in SEQ ID NO.1. The lactoferrin peptides and lactoferrin provided by this invention can specifically bind to and inhibit the activity of 3C protease, directly inhibiting viral replication by blocking its cleavage function of viral polyproteins. The mechanism is clear and has high affinity. Since 3C protease is highly conserved in the Picornaviridae family, it has broad-spectrum inhibitory effects against enteroviruses such as EV-A71 and CV-A9, and has a wide range of applications. Furthermore, it is derived from natural substances, has good biocompatibility and high safety, and can be made into various forms such as pharmaceuticals and antiviral daily necessities, with diverse application scenarios. This invention provides a new approach for developing antiviral drugs targeting 3C protease based on natural proteins, and has significant theoretical and applied value.