2 results about "Multidimensional liquid chromatography" patented technology

The utility model relates to the technical field of chromatographic instruments, and discloses a multi-dimensional liquid chromatograph which comprises a dustproof box, two sliding rails are arranged on the inner bottom wall of the dustproof box, pulleys are connected in the sliding rails in a sliding manner, the top surfaces of the pulleys are fixedly connected with a multi-dimensional liquid chromatograph main body, and the multi-dimensional liquid chromatograph main body is fixedly connected with the inner bottom wall of the dustproof box. The top surface of the multi-dimensional liquid chromatograph main body is fixedly connected with a storage rack. According to the multi-dimensional liquid chromatograph, through the arrangement of the clamping assembly and the clamping ring, when the multi-dimensional liquid chromatograph is used, a solvent bottle is inserted into a placement groove, a spring, a rubber pad A and a rubber pad B are extruded outwards under extrusion force, and after the solvent bottle is placed, the spring, the rubber pad A and the rubber pad B have elasticity to push the clamping ring to abut against the outer wall of the solvent bottle, so that the effect of limiting the solvent bottle from shaking back and forth is achieved; the solvent bottle is prevented from shaking and toppling over in the transportation process or when an operator moves the solvent bottle, the service life of the solvent bottle is prolonged, and the detection cost is saved.

Described herein are multi-dimensional liquid chromatography (MDLC) systems and methods of performing MDLC. The MDLC systems include a valve configuration that enables modulation of a flow containing an analyte in an eluent of a first dimension liquid chromatography system such that the analyte can be captured in a fluidic circuit and subsequently provided to a second dimension liquid chromatography system. Various system embodiments are provided with small instrument size, including the option of using the same detector for both the first and second dimensions, enabling improved valve timing operations, and reduced magnitude and impact of pressure pulses. Additionally, the modulator can enable dilution of the analyte, and the use of incompatible mobile phases and mobile phase flow rates on the first and second dimensions.