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Medicament for treating chronic cerebral circulation insufficiency and preparation method

A technology of cerebral blood supply insufficiency and drugs, which is applied in the direction of drug combinations, medical formulas, and medical preparations containing active ingredients, etc., can solve the problems of not being able to increase the application of blood-promoting drugs, excessive yang qi growth, disturbing liver fire, etc., and achieve platelet Good aggregation rate, good treatment, and the effect of reducing high shear viscosity

Active Publication Date: 2011-08-31
QIANFOSHAN HOSPITAL OF SHANDONG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These medicines in the prior art, due to the adoption of a variety of medicines for promoting blood circulation and removing blood stasis, take them for a long time, which can easily damage the righteousness and affect the spleen and stomach. Among them, the medicines for nourishing Qi and promoting yang will cause the disadvantages of disturbing liver fire and excessive growth of yang qi
The medicines of the prior art are limited by these unfavorable factors of promoting blood circulation and removing blood stasis and nourishing qi and raising yang, making them more unable to increase the application degree of blood promoting drugs

Method used

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  • Medicament for treating chronic cerebral circulation insufficiency and preparation method
  • Medicament for treating chronic cerebral circulation insufficiency and preparation method
  • Medicament for treating chronic cerebral circulation insufficiency and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] The medicine for the treatment of chronic cerebral insufficiency is made from the following raw materials by weight: Salvia miltiorrhiza 350g, Codonopsis 300g, Coptidis 120g, Chuanxiong 200g, Curcuma 200g, Hawthorn 300g, Seaweed 250g, Gastrodia elata 200g, Coix seed 300g and Turmeric 200g .

[0035] Preparation method: add Coptis chinensis to 8 times its mass of water, decoct for 2 hours, filter, add 6 times its mass of water to the dregs, decoct twice as above for 1.5 hours and 1 hour respectively, combine 3 Subsequent decoction, concentrated under reduced pressure to a thick paste with a relative density of 1.30-1.35 (measured at 60°C), for use; 9 herbs of Salvia miltiorrhiza, Codonopsis, Chuanxiong, Curcuma, Hawthorn, Seaweed, Gastrodia elata, Coix Seed, Curcuma Radix are added to 9 herbs 8 times the quality of water, decocted for 2 hours, filtered, and then added 6 times the quality of 9 herbs to the dregs, decocted 2 times as above for 1.5 hours and 1 hour respecti...

Embodiment 2

[0037] The medicine for the treatment of chronic cerebral insufficiency is made from the following raw materials by weight: 150g of Salvia miltiorrhiza, 100g of Codonopsis pilosula, 10g of Coptis chinensis, 20g of Chuanxiong, 20g of Curcuma, 100g of Hawthorn, 100g of seaweed, 20g of Tianma, 100g of Coix Seed and 20g of Turmeric .

[0038] Preparation method: add Coptis chinensis to water with 4 times its mass, decoct for 3 hours, filter, add 4 times its mass of water to the medicinal residues, decoct twice as above for 1.5 hours and 2 hours respectively, combine 3 Subsequent decoction, concentrated under reduced pressure to a thick paste with a relative density of 1.30-1.35 (measured at 60°C), for use; 9 herbs of Salvia miltiorrhiza, Codonopsis, Chuanxiong, Curcuma, Hawthorn, Seaweed, Gastrodia elata, Coix Seed, Curcuma Radix are added to 9 herbs 5 times the quality of water, decocted for 2 hours, filtered, and then added 5 times the quality of 9 herbs to the dregs, decocted 2...

Embodiment 3

[0040] The medicine for the treatment of chronic cerebral insufficiency is made from the following raw materials by weight: 550g of Salvia miltiorrhiza, 500g of Codonopsis pilosula, 320g of Coptis chinensis, 400g of Chuanxiong, 400g of Curcuma, 500g of Hawthorn, 400g of seaweed, 400g of Tianma, 500g of Coix Seed and 400g of Turmeric .

[0041] Preparation:

[0042] (1) Coptis chinensis is added to the water of 2 times of its quality, decocted for 2 hours, filtered, and the medicinal residues add the water of 2 times of Coptis chinensis quality, decocted 2 times as above, merged 3 times of decoctions, and concentrated under reduced pressure to relative Density 1.30~1.35 (measured at 60℃) thick paste;

[0043] (2) Add 9 herbs of Salvia, Codonopsis, Chuanxiong, Curcuma, Hawthorn, Seaweed, Gastrodia, Coix Seed, and Curcuma into water with 2 to 9 times their mass, decocted for 2 hours, filtered, and then added 9 herbs to the dregs Water with 2 times the amount of the medicine, de...

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Abstract

The invention discloses a medicament for treating the chronic cerebral circulation insufficiency and a preparation method. The medicament comprises salvia, codonopsis, coptis, chuanxiong, zedoary, crataegus, seaweed, gastrodia, coix seed and curcuma as raw materials. The preparation method comprises the following steps of: adding water to the coptis for decoction, concentrating the water decoction into thick paste, adding water to other raw materials for decoction, concentrating the water decoction into thick paste, combing the two pieces of thick paste, adding a suitable amount of dextrin, and uniformly mixing, drying, crushing and pelletizing the mixture. The medicament has the effects of simultaneously removing blood stasis, promoting blood circulation, eliminating phlegm and invigorating spleen, can better treat the arteriosclerosis, remarkably improve the integral of syndrome of intermingled phlegm and blood stasis for the granule fraction of removing blood stasis and promoting blood circulation, has better effects of reducing the whole blood high-shear viscosity, low-shear viscosity, plasma viscosity and platelet aggregation ratio, and has the advantages of high safety and no influence on hemogram, liver and kidney functions and the like.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine. Background technique [0002] Cerebral insufficiency refers to a series of clinical manifestations of cerebral dysfunction due to various reasons leading to chronic extensive insufficiency of blood supply to the brain, resulting in cerebral ischemia and hypoxia. Its clinical manifestations are: motor nerve dysfunction, sensory dysfunction, abnormal mental consciousness and so on. [0003] Clinically, when the cerebral blood flow gradually decreases, the first clinical manifestations are various subjective symptoms. With the further decrease of cerebral blood flow, mental symptoms will gradually appear. Only when the cerebral blood flow decreases to a considerable extent neurological symptoms and signs. At the same time, with the gradual decline of blood flow, the organic changes in the brain gradually become more obvious. If chronic cerebral insufficiency is not well contr...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P9/10
Inventor 李长生杨晓妮程广清韩莹
Owner QIANFOSHAN HOSPITAL OF SHANDONG
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