This invention provides a
traditional Chinese medicine compound preparation and its application in the preparation of drugs for treating cardiovascular and cerebrovascular diseases, belonging to the field of
traditional Chinese medicine technology. The
traditional Chinese medicine compound preparation comprises the following raw materials in parts by weight: 10-20 parts
bee pollen, 8-15 parts
curcumin, 5-10 parts γ-
aminobutyric acid, 5-12 parts
Litsea cubeba leaf, 10-20 parts hawthorn, 5-10 parts
Lindera strychnifolia leaf, 10-20 parts
kudzu root, 5-12 parts
ginseng, 8-15 parts
Polygonatum sibiricum, 6-12 parts
Sophora japonica flower
bud, 3-8 parts
tangerine peel, and 1-5 parts L-
cysteine. This invention significantly improves the water
solubility, stability, and
bioavailability of
curcumin by constructing a
chlorophyll zinc / LDH
nanosheet composite carrier to load
curcumin. A compound preparation of traditional Chinese
medicine was prepared by combining a complex loaded with curcumin with various food and
medicine homologous ingredients. This traditional Chinese
medicine compound preparation can significantly reduce
whole blood viscosity,
plasma viscosity and
platelet aggregation rate in rats with acute
blood stasis model, has anti-thrombotic effect, and significantly promotes the
recovery of
neurological function in rats with focal cerebral
ischemia and reduces the volume of
cerebral infarction.