Water-soluble preparation of anesthetic eugenol for fish and preparation method thereof

A technology for eugenol and anesthetics, applied in the field of water-soluble preparations and its preparation, can solve the problems of eugenol being difficult to dissolve in water, unfavorable large-scale use, and limited popularization and application, and achieve shortened anesthesia time, low toxicity, and good drug effect Effect

Inactive Publication Date: 2012-10-03
INST OF AGRO PROD PROCESSING SCI & TECH SICHUAN ACAD OF AGRI SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Because eugenol itself is difficult to dissolve in water, it is not conducive to large-scale use in production, thus limiting its popularization and application

Method used

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  • Water-soluble preparation of anesthetic eugenol for fish and preparation method thereof
  • Water-soluble preparation of anesthetic eugenol for fish and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] The preparation of Example 1 of the present invention is made of the following raw materials by weight:

[0021] Eugenol 20,

[0022] ethanol 30,

[0023] Gelatin 4,

[0024] Ion-free distilled water 100.

[0025] The preparation method of Example 1 preparation of the present invention is as follows:

[0026] (1), ingredients in proportion;

[0027] (2), respectively mix eugenol with ethanol, ion-free distilled water and gelatin to form a mixed liquid, add ion-free distilled water and gelatin mixed liquid in the mixed liquid of eugenol and ethanol, stir and react at a constant temperature of 35°C for 20 Minutes, into a transparent water-soluble preparation.

Embodiment 2

[0029] Example 2 preparation of the present invention is made of the following raw materials by weight:

[0030] Eugenol 10,

[0031] ether 10,

[0032] Agar 1,

[0033] Ion-free distilled water 100.

[0034] The preparation method of Example 2 of the present invention is as follows:

[0035] (1), ingredients in proportion;

[0036] (2), respectively mix eugenol and ether, ion-free distilled water and agar to form a mixed liquid, add ion-free distilled water and agar mixed liquid in the mixed liquid of eugenol and ether, stir and react at a constant temperature of 50°C for 30 Minutes, into a transparent water-soluble preparation.

Embodiment 3

[0038] Example 3 preparation of the present invention is made of the following raw materials by weight:

[0039] Eugenol 30,

[0040] Chloroform 15,

[0041] Alginate 10,

[0042] Ion-free distilled water 100.

[0043] The preparation method of Example 3 of the present invention is as follows:

[0044] (1), ingredients in proportion;

[0045] (2), respectively mix eugenol with chloroform, ion-free distilled water and seaweed fat to form a mixed liquid, add ion-free distilled water and seaweed fat mixed liquid into the mixed liquid of eugenol and chloroform, and stir at a constant temperature of 55°C React for 10 minutes to become a transparent water-soluble preparation.

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Abstract

The invention provides a water-soluble preparation of anesthetic eugenol serving as an effective ingredient for fish. The preparation is prepared from the following raw materials in part by weight: 10 to 30 parts of eugenol, 10 to 30 parts of solvent, 1 to 10 parts of thickening agent and 100 parts of deionized distilled water. The preparation has good effect, short anesthesia time and low toxicity, and is favorable for scale application. The invention also provides a preparation method for the preparation. The preparation method is simple.

Description

Technical field: [0001] The invention relates to a water-soluble preparation of anesthetic eugenol for fish and a preparation method thereof. Background technique: [0002] Eugenol is the common name for 4-allyl-2-methoxyphenol, and its structural formula is as follows. It mainly exists in the oil of clove basil (Oci-mum gratissimum L) and the oil of cinnamon leaves of camphor, and is a kind of aromatic oil. [0003] [0004] In 1972, Endo of Japan discovered that this spice had a strong anesthetic effect on fish, and began to use it as an anesthetic for fish for a series of research. In recent years, with in-depth research, eugenol, a natural spice, has been used as an anesthetic for fish because it is cheap and easy to obtain, and has no effect on human health. Anesthesia of animals. Among them, Japan has listed it as one of the fish anesthetics used in fishery production. [0005] Because eugenol itself is difficult to dissolve in water, it is not conducive to larg...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/00A61K31/05A61K47/42A61K47/36A61P23/00
Inventor 曾晓丹曹阳
Owner INST OF AGRO PROD PROCESSING SCI & TECH SICHUAN ACAD OF AGRI SCI
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