Collagen eye drops and preparation method thereof

A technology of collagen and eye drops, applied in peptide/protein components, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems of eye irritation, difficult absorption, large molecular weight, etc., and achieve excellent moisturizing and lubrication. The effect of good curative effect and good biological function

Active Publication Date: 2011-10-12
XIAN GIANT BIOGENE TECH CO LTD
View PDF2 Cites 9 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This technology improves how we use certain substances that help promote or stimulate new cells from our body's own tissues called collagens (which are specialized connective proteins found primarily within animal fibers). These chemical compounds have been shown effective for various medical purposes such as reducing inflammation associated with arthritis by helping blood vessels grow faster through increased production of hormones like progesterone. They also provide an antioxidant defense system against free radical damage caused by reactive oxygen species generated when lamps get too hot. Additionally they enhance skin hydrating and prevent wrinkles due to lacking water content.

Problems solved by technology

This patented technical problem addressed in this patents relates to finding an effective way for reducing eye strain caused by stress or lacking ingredients like vitamins that may affect vision during working hours without causing any side effects on their users' healthy skin.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Step 1: Combine 50 mg of animal-derived collagen, 100 mg of taurine, and 5 mg of vitamin B 6 , 1 mg of naphazoline hydrochloride, 10 mg of chlorpheniramine maleate and 30 mg of ethylparaben were dissolved in 0.9% sodium chloride isotonic solution to prepare 100 ml of mixed solution, and the pH value was adjusted Between 6.5 and 40°C water bath for 30 minutes;

[0043] Step 2: Sterilize while it is hot in a sterile operating table. The method of sterilization is microporous membrane filtration. The microporous membrane used is a hydrophilic filter membrane with a pore size of 0.22 μm, and the collagen eye drops are obtained by subpackaging .

[0044] Collagen eye drops in this case were tested as follows:

[0045] Fifteen healthy big-eared white rabbits, with a body weight of 2.0±0.2kg, were randomly divided into three groups A, B, and C, with 5 rabbits in each group, and were irradiated with light with an intensity of 4000-5000liux for 5 days. Rabbit eyes were used t...

Embodiment 2

[0048] Step 1: Combine 100 mg of animal-source collagen, 150 mg of taurine, and 10 mg of vitamin B 12 , 1 milligram of naphazoline hydrochloride, 15 milligrams of chlorpheniramine maleate and 40 milligrams of benzalkonium bromide, dissolved in 0.9% sodium chloride isotonic solution, prepared into 100 milliliters of mixed solution, and the pH value was adjusted Between 7.0 and 40°C water bath for 30 minutes;

[0049] Step 2: Sterilize while it is hot in a sterile operating table. The method of sterilization is microporous membrane filtration. The microporous membrane used is a hydrophilic filter membrane with a pore size of 0.22 μm, and the collagen eye drops are obtained by subpackaging .

[0050] Collagen eye drops in this example were tested as follows:

[0051]Fifteen healthy big-eared white rabbits, with a body weight of 2.0±0.2kg, were randomly divided into three groups A, B, and C, with 5 rabbits in each group, and were irradiated with light with an intensity of 4000-5...

Embodiment 3

[0054] Step 1: Combine 150 mg of human-like collagen, 150 mg of taurine, and 10 mg of vitamin B 12 , 2 mg of oxymetazoline hydrochloride, 15 mg of chlorpheniramine maleate and 40 mg of levofloxacin, dissolved in 0.9% sodium chloride isotonic solution, prepared into 100 ml of mixed solution, adjusted to pH 7.0 In between, keep warm in a 40°C water bath for 30 minutes;

[0055] Step 2: Sterilize while it is hot in a sterile operating table. The method of sterilization is microporous membrane filtration. The microporous membrane used is a hydrophilic filter membrane with a pore size of 0.22 μm, and the collagen eye drops are obtained by subpackaging .

[0056] Collagen eye drops in this example were tested as follows:

[0057] Fifteen healthy big-eared white rabbits, with a body weight of 2.0±0.2kg, were randomly divided into three groups A, B, and C, with 5 rabbits in each group, and were irradiated with light with an intensity of 4000-5000liux for 5 days. Rabbit eyes were us...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Apertureaaaaaaaaaa
Login to view more

Abstract

The invention relates to collagen eye drops and a preparation method thereof. The type of the conventional antifatigue eye drops is mainly divided into a type of ocular tissue similar objects and a type of traditional Chinese medicines, the main raw material of the eye drops in type of the ocular tissue similar objects is sodium hyaluronate which has large molecular weight and is not easy to be absorbed; and the eye drops in type of the traditional Chinese medicines has bad histocompatibility with human eyes, and generates a stimulation effect on the eyes when used for a long time. The collagen eye drops disclosed by the invention is prepared by adding auxiliary materials, such as a retina growth facilitating auxiliary material, a vitamin auxiliary material, an angiotonics auxiliary material, an antihistamine auxiliary material and a preservative auxiliary material, to collagen and an isotonic solution. The collagen eye drops has excellent biological functions, high adhesivity and hydrophily, and can play the roles of supporting and lubricating during cell migration; meanwhile, various necessary elements required by the eyes can be met, the surviving environment of ocular cells can be improved, and the metabolism of the eyes can be facilitated, and the purpose of nutrition is realized; in addition, the collagen eye drops has excellent moistening and lubricating curative effects and also has excellent curative effects on xerophthalmus and asthenopia.

Description

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Owner XIAN GIANT BIOGENE TECH CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap