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Feed additive enteric-coated sustained-release pellet with function of preventing and treating poultry respiratory syndromes and preparation method for feed additive enteric-coated sustained-release pellet

A technology of feed addition and slow-release pellets is applied in respiratory diseases, medical preparations containing active ingredients, animal feed, etc. It can solve the problems of bacterial resistance, antibiotic residues, death, etc., and improve the feed conversion rate. , Improve respiratory function, the effect of small dosage

Inactive Publication Date: 2015-07-01
天津市静海县科杰制剂技术创新研究中心
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This invention relates to an oral administration system for delivering drugs that target specific areas within the body called lungs where they are needed most effectively without causing harmful side reactions like those associated with traditional medicine methods such as ingestion therapy. These systems help reduce damage from disease outbreaks while still providing effective treatment against both bacterial and viruses related illnesses.

Problems solved by technology

This patents discuss how we see an issue where traditional methods used to fight against disease like avian influenza (AIV) require more expensive chemical agents than what they aim to achieve. Additionally, current treatment options involve administering these substances repeatedly over time or even after exposure, causing potential negative impact upon both humans and animals' wellbeing.

Method used

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  • Feed additive enteric-coated sustained-release pellet with function of preventing and treating poultry respiratory syndromes and preparation method for feed additive enteric-coated sustained-release pellet
  • Feed additive enteric-coated sustained-release pellet with function of preventing and treating poultry respiratory syndromes and preparation method for feed additive enteric-coated sustained-release pellet
  • Feed additive enteric-coated sustained-release pellet with function of preventing and treating poultry respiratory syndromes and preparation method for feed additive enteric-coated sustained-release pellet

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] The preparation method of feed-added enteric-coated slow-release pellets with the function of preventing and treating poultry respiratory diseases comprises the following steps:

[0023] (1) Weigh raw materials by mass: 1% water-soluble vitamin A, 0.1% water-soluble vitamin D, 1% water-soluble vitamin E, 0.8% thymol, 0.2 cinnamaldehyde, 5% menthol, 10% eucalyptus oil, 50% malt paste Essence, 8% sodium carboxymethylcellulose, 14.9% lactose, 4% coating liquid, 5% model is the Eudragit enteric coating liquid of Eudragit L30D-55, and described coating liquid is that mass concentration is 7% Opadry II (HPMC) aqueous suspension;

[0024] (2) making the lactose described in step (1) into an aqueous lactose solution with a mass concentration of 17%;

[0025] (3) Put water-soluble vitamin A, water-soluble vitamin D, water-soluble vitamin E, thymol, cinnamaldehyde, menthol, eucalyptus oil, maltodextrin, sodium carboxymethylcellulose and the lactose aqueous solution obtained in...

Embodiment 2

[0028] The preparation method of feed-added enteric-coated slow-release pellets with the function of preventing and treating poultry respiratory diseases comprises the following steps:

[0029] (1) Weigh raw materials by mass: 1% water-soluble vitamin A, 0.1% water-soluble vitamin D, 1% water-soluble vitamin E, 0.1% thymol, 0.3% cinnamaldehyde, 8.5% menthol, 19% eucalyptus oil, 10% malt Dextrin, 15% sodium carboxymethylcellulose, 28% lactose, 7% coating liquid, 10% model is the Eudragit enteric coating liquid of EudragitL30D-55, and described coating liquid is that mass concentration is 5% Opadry II (HPMC) aqueous suspension;

[0030] (2) making the lactose described in step (1) into an aqueous lactose solution with a mass concentration of 5%;

[0031] (3) Put water-soluble vitamin A, water-soluble vitamin D, water-soluble vitamin E, thymol, cinnamaldehyde, menthol, eucalyptus oil, maltodextrin, sodium carboxymethylcellulose and the lactose aqueous solution obtained in step...

Embodiment 3

[0034] The preparation method of feed-added enteric-coated slow-release pellets with the function of preventing and treating poultry respiratory diseases comprises the following steps:

[0035] (1) Weigh raw materials by mass: 1% water-soluble vitamin A, 0.1% water-soluble vitamin D, 1% water-soluble vitamin E, 0.1% thymol, 0.1% cinnamaldehyde, 1% menthol, 1% eucalyptus oil, 90% malt Dextrin, 1% sodium carboxymethylcellulose, 1.7% lactose, 1% coating liquid, 2% model is the Eudragit enteric coating liquid of EudragitL30D-55, and described coating liquid is that mass concentration is 8% Opadry II (HPMC) aqueous suspension;

[0036] (2) making the lactose described in step (1) into an aqueous lactose solution with a mass concentration of 30%;

[0037] (3) Put water-soluble vitamin A, water-soluble vitamin D, water-soluble vitamin E, thymol, cinnamaldehyde, menthol, eucalyptus oil, maltodextrin, sodium carboxymethylcellulose and the lactose aqueous solution obtained in step (2...

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Abstract

The invention discloses a feed additive enteric-coated sustained-release pellet with a function of preventing and treating poultry respiratory syndromes and a preparation method for the feed additive enteric-coated sustained-release pellet. The enteric-coated sustained-release pellet is prepared from the following raw materials: water-soluble vitamin A, water-soluble vitamin D, water-soluble vitamin E, thymol, cinnamyl aldehyde, menthol, eucalyptus oil, maltodextrin, sodium carboxymethylcellulose, lactose and a coating solution which is a Eudragit enteric-coated coating solution with a model of Eudragit L30D-55, wherein the coating solution is water suspension with mass concentration of 5%-8%. The feed additive enteric-coated sustained-release pellet with the function of preventing and treating poultry respiratory syndromes disclosed by the invention has a treatment effect on sick chicken with respiratory syndromes due to artificial infection of chicken infectious bronchitis virus (M41 strain), can effectively improve the respiratory tract function, is small in dosage, quick in effect-taking, and has the effects of promoting growth and increasing a feed conversion rate.

Description

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Claims

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Application Information

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Owner 天津市静海县科杰制剂技术创新研究中心
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