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Anti-bacterial high-viscosity medical glue and preparation method thereof

A technology of glue and extract, applied in the field of medical materials, can solve problems such as wound cracking and bleeding, wound infection, and insufficient bonding strength, and achieve the effects of excellent comprehensive performance, easy industrialization, and simple operation

Inactive Publication Date: 2016-10-26
林春梅
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the bonding strength of the existing medical glue is not enough, and the wound is easy to crack and bleed due to exercise. In addition, there are also disadvantages such as poor antibacterial effect, easy to cause wound infection, and easy to bring certain stimulation to biological tissues.

Method used

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  • Anti-bacterial high-viscosity medical glue and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] An antibacterial high-adhesion medical glue, comprising the following components in parts by weight: 40 parts of isopropyl 2-cyanoacrylate, 25 parts of polyisoprene, 18 parts of polypropylene, 4 parts of povidone iodine, sulfuric acid 3 parts of magnesium, 3 parts of naringenin, 2 parts of red stone fat nano powder, 5 parts of vitamin A palmitate, 2 parts of plant essential oil, 2 parts of paraffin, 2 parts of alginate, 1 part of disodium EDTA, methacrylamide 4 parts, 4 parts of polyvinyl alcohol, 3 parts of dioctyl phthalate, 2 parts of 1.5g / ml luffa extract, 1 part of 0.8g / ml white and extract, 150 parts of glycerin, 100 parts of sterile water.

[0022] The plant essential oil is a mixture of litsea cubeba essential oil, lemongrass essential oil and fennel essential oil in a weight ratio of 3:1:2.

[0023] The loofah extract is the ethanol or methanol extract of loofah, and the specific extraction steps are: take the dried loofah and pulverize it, add 20 times the wei...

Embodiment 2

[0031] An antibacterial high-adhesion medical glue, comprising the following components in parts by weight: 49 parts of isopropyl 2-cyanoacrylate, 30 parts of polyisoprene, 21 parts of polypropylene, 6 parts of povidone iodine, sulfuric acid 4 parts of magnesium, 5 parts of naringenin, 3 parts of red stone fat nano powder, 7 parts of vitamin A palmitate, 4 parts of plant essential oil, 3 parts of paraffin, 3 parts of alginate, 3 parts of disodium EDTA, methacrylamide 6 parts, 5 parts of polyvinyl alcohol, 4 parts of dioctyl phthalate, 3 parts of 1.5g / ml loofah extract, 2 parts of 0.8g / ml white and extract, 175 parts of glycerin, 130 parts of sterile water.

[0032] The plant essential oil is a mixture of litsea cubeba essential oil, lemongrass essential oil and fennel essential oil in a weight ratio of 3:2:1.

[0033] The loofah extract is the ethanol or methanol extract of loofah, and the specific extraction steps are: take the dried loofah and grind it, add 35 times the weig...

Embodiment 3

[0041] An antibacterial high-adhesion medical glue, comprising the following components in parts by weight: 58 parts of isopropyl 2-cyanoacrylate, 36 parts of polyisoprene, 25 parts of polypropylene, 8 parts of povidone iodine, sulfuric acid 6 parts of magnesium, 7 parts of naringenin, 4 parts of red stone fat nano powder, 9 parts of vitamin A palmitate, 6 parts of plant essential oil, 4 parts of paraffin, 4 parts of alginate, 5 parts of disodium EDTA, methacrylamide 8 parts, polyvinyl alcohol 7 parts, dioctyl phthalate 6 parts, 1.5g / ml loofah extract 4 parts, 0.8g / ml white and extract 3 parts, glycerin 200 parts, sterile water 160 parts.

[0042] The plant essential oil is a mixture of litsea cubeba essential oil, lemongrass essential oil and fennel essential oil in a weight ratio of 2:1:1.

[0043]The loofah extract is the ethanol or methanol extract of loofah, and the specific extraction steps are: take the dried loofah and grind it, add 50 times the weight of 95% mass conc...

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Abstract

The invention discloses an anti-bacterial high-viscosity medical glue, which is prepared from the following ingredients: 2-cyano-acrylate isopropyl, polyisoprene, polypropylene, povidone iodine, magnesium sulfate, naringenin, halloysitum rubrum nano-powder, vitamin A palmitate, plant essential oil, paraffins, alginate, disodium EDTA, methacrylamide, polyvinyl alcohol, dioctyl phthalate, 1.5g/ml luffa extract, 0.8g/ml rhizoma bletillae extract, glycerol and sterile water. The invention further discloses a preparation method of the anti-bacterial high-viscosity medical glue. The adhesive strength and 48-hour compressive strength of the medical glue are in a relatively high level, the medical glue is high in anti-bacterial ratio, short in hemostasis time, high in overall healing efficiency, free from irritation on wound tissues and excellent in overall performance, and conforms to the application requirements of clinics for the medical glue.

Description

technical field [0001] The invention belongs to the technical field of medical materials, and in particular relates to an antibacterial high-adhesion medical glue and a preparation method thereof. Background technique [0002] In daily life, it is unavoidable to be injured by the external environment, resulting in scars, wounds and even a lot of bleeding. In this case, the slightly injured will generally use gauze and other dressing materials to treat the wound, but gauze and other dressing materials are easy Wound infection is caused, and the used dressing materials also need follow-up treatment, otherwise it will pollute the environment. In addition, the dressing material needs to be torn off to replace a new dressing material after being used for a period of time. During the tearing process, it is easy to cause secondary damage to the wound tissue and bring severe pain to the user. Severely injured people need to use medical thread for suturing, which undoubtedly increas...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L24/06A61L24/02A61L24/08A61L24/00
CPCA61L24/06A61L24/0005A61L24/001A61L24/0015A61L24/0031A61L24/02A61L24/08A61L2300/404A61L2300/412A61L2400/04C08L29/04C08L5/04C08L47/00C08L23/12C08L39/06
Inventor 林春梅
Owner 林春梅
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