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72results about How to "Improve healing efficiency" patented technology

Self-Healing Composite of Thermoset Polymer and Programmed Super Contraction Fibers

A composition comprising thermoset polymer, shape memory polymer to facilitate macro scale damage closure, and a means for molecular scale healing is disclosed; the composition has the ability to resolve structural defects by a bio-mimetic close-then heal process. In use, the shape memory polymer serves to bring surfaces of a structural defect into approximation, whereafter use of the means for molecular scale healing allowed for movement of the healing means into the defect and thus obtain molecular scale healing. The means for molecular scale healing can be a thermoplastic such as fibers, particles or spheres which are used by heating to a level at or above the thermoplastic's melting point, then cooling of the composition below the melting temperature of the thermoplastic. Compositions of the invention have the ability to not only close macroscopic defects, but also to do so repeatedly even if another wound / damage occurs in a previously healed / repaired area.
Owner:BOARD OF SUPERVISORS OF LOUISIANA STATE UNIV & AGRI & MECHANICAL COLLEGE

Modified cellulose nanofiber membrane based on layer-by-layer self-assembly of lysozyme and silk protein based as well as preparation and application thereof

The invention discloses a modified cellulose nanofiber membrane based on layer-by-layer self-assembly of lysozyme and silk protein as well as preparation and application thereof and belongs to the technical fields of high polymer materials and biomedical materials. According to the invention, a cellulose acetate nanofiber membrane is prepared by utilizing an electrospinning technique and lysozyme and silk protein which are opposite in charges are alternately assembled on the surface of the cellulose nanofiber membrane by adopting a layer-by-layer assembly technique so as to obtain the modified cellulose nanofiber membrane disclosed by the invention. The membrane disclosed by the invention has the advantages that the preparation equipment is simple, raw materials are low in cost, non-toxic and biodegradable, the whole process is simple to operate and the number of lysozyme / silk protein layers is controllable. Proved by antibacterial tests, cell survival tests, cell fluorescence staining tests, cell adhesion tests and in vitro wound healing tests, the modified cellulose nanofiber membrane disclosed by the invention has good antibacterial performance and cell adhesiveness and is capable of increasing the wound healing efficiency and preventing the wound infection, so that the membrane is a very good wound repairing material and can be used in the wound repairing field.
Owner:HUBEI SAILUO BIOLOGICAL MATERIAL CO LTD

3D-printing wound dressing material based on silk microsphere bio-ink and preparation method thereof

The invention provides a 3D-printing wound dressing material based on silk microsphere bio-ink and a preparation method thereof. The preparation method includes the following steps: transferring silkmicrosphere bio-ink, which includes silk protein microspheres coating aspirin, silk protein water solution, ultraviolet initiator and polyvinyl alcohol ester, into a syringe of a 3D-printing machine;with a cotton gauze as a base printing cloth, printing the surface of the cotton gauze with the silk microsphere bio-ink according to a periodically circulated cross-network structure model; and rapidly curing and shaping the 3D-printing wound dressing material under ultraviolet irradiation. The product is based on 3D-printing technology, wherein the formed cross-network structure contains regularly arranged silk microspheres, and the silk microsphere bio-ink coating layer cures on the surface of the cotton gauze and does not completely penetrate through the cotton gauze. The 3D-printing wounddressing material has good mechanical performance and biocompatibility and excellent slow-release performance, can protect a wound for a long time and can accelerate healing of the wounding.
Owner:YANCHENG INST OF IND TECH

Negative pressure wound dressing

InactiveUS20190083322A1Improving wound healing efficiencyImprove healing efficiencyAdhesive dressingsIntravenous devicesWound healingNegative pressure wound dressing
A negative pressure wound dressing is provided. The negative pressure wound dressing sequentially includes a barrier layer, an indicating layer, a liquid impermeable, a liquid impermeable, gas permeable layer, an absorbent layer and a wound contacting layer, wherein, the barrier layer comprises a connecting hole for fluidly connecting a negative pressure source, and the indicating layer comprises at least one visual indicating element on the surface adjacent to the barrier layer. By using the negative pressure wound dressing of the present invention, the user can be reminded to replace the dressing timely by the visual indicating element which can detect the wound exudates absorption in the absorbing layer to effectively improve the wound healing.
Owner:BENQ MATERIALS CORP

High-temperature thin film sensor with self-healing composite protective layer and preparation method thereof

The invention belongs to the technical field of a sensor, and provides a high-temperature thin film sensor with a self-healing composite protective layer and a preparation method thereof, and aims to realize miniaturization and thin-film application of the sensor. The thin film sensor is composed of a substrate, a thin film sensor sensitive functional layer and the self-healing composite protective layer, which are arranged from bottom to top in order, wherein the structure of the self-healing composite protective layer comprises YSiO / HfSiBCN periodic multilayer membrane structures from bottom to top in order, and the lowest layer and the topmost layer of the protective layer are both YSiO low-oxygen diffusion coefficient layers. The high-temperature thin film sensor adopts the self-healing composite protective layer with the self-healing composite protective layer, the YSiO low-oxygen diffusion coefficient layers and HfSiBCN self-healing layers are alternately deposited to form an anti-oxidative protection system with layers of protection, and therefore the thin film sensor can work for a long time under the condition of high temperature of 600-1500DEG C and has the advantages of high temperature resistance, corrosion resistance, oxidation resistance, fast response, etc.
Owner:UNIV OF ELECTRONICS SCI & TECH OF CHINA

Single-component healing capsule and self-healing concrete

The invention provides a single-component healing capsule and self-healing concrete. The single-component healing capsule provided by the invention comprises a capsule wall, a plugging material plugged at the opening of the capsule wall and a single-component healer plugged in the capsule wall, wherein the single-component healer comprises polyurethane and diluter. The single-component healing capsule provided by the invention takes a mixture of polyurethane and diluter as the healer, and the intermolecular action force of the polyurethane is changed through dilution of the diluter, so that the healer has favorable flowability, and the healer can flow evenly in a crack and be solidified and cemented within certain time after the capsule is ruptured. Experimental results indicate that the healer can be uniformly released into the crack after the single-component healing capsule is ruptured; crack healing is realized through cementation with concrete; and the healing efficiency can be up to 32.2% one day after two capsules are ruptured, the healing efficiency can be up to 77.6% two days after two capsules are ruptured, and the healing efficiency can be up to 75.2% three days after two capsules are ruptured.
Owner:SHANDONG UNIV OF SCI & TECH

Ultraviolet self-healing polyamide material, and preparation method and self-healing method thereof

The invention discloses an ultraviolet self-healing polyamide material. The ultraviolet self-healing polyamide material is formed by compounding metal ions with a ligand polyamide through coordinationbonds, wherein the polyamide contains an azodipyridine structure; and a molar ratio of azodipyridine units in the polyamide to the metal ions is 1:(0.1-1). A preparation method of the ultraviolet self-healing polyamide material comprises the following steps: reacting azodipyridinecarboxylic acid with thionyl chloride under a 80 DEG C refluxing condition to synthesize azodipyridyl acyl chloride; synthesizing polyamide from the azodipyridinecarboxylic acid and long-chain diamine at room temperature under the catalysis of triethylamine with dichloromethane as a solvent; and stirring mixed solution of the obtained dichloromethane solution of the polyamide containing the azodipyridine structure and a methanol solution of a metal salt at room temperature for 24 h, and then heating the obtainedsolution to remove the organic solvent in order to obtain the ultraviolet self-healing polyamide material. The self-healing polyamide material can be rapidly self-healed through the reversible metal coordination bonds under the irradiation of ultraviolet light, and the healing efficiency is close to 100%.
Owner:SOUTHWEST PETROLEUM UNIV

High-strength aluminum alloy sheet resistance spot welding molten core inner crack healing method

The invention discloses a high-strength aluminum alloy sheet resistance spot welding molten core inner crack healing method. The method is used for solving the technical problem that an existing resistance spot welding molten core inner crack healing method is poor in efficiency. According to the technical scheme, the mode that an upper shaft shoulder and a lower shaft shoulder rotate and rub synchronously to generate heat is adopted, double-faced synchronous healing processing is conducted on the same molten core inner crack on an upper face and a lower face of a spot welding joint, compared with healing processing sequentially conducted on faces separately, the friction residence time can be shortened, and healing efficiency is improved; according to the characteristic that a high-strength sheet aluminum alloy spot welding structure piece is poor in deformation resistance, through self-supporting functions of the upper shaft shoulder and the lower shaft shoulder, no base plate is needed, and healing of mass molten core inner cracks of large sheet multi-point spot welding structure pieces can be achieved; the friction face of a healing tool is provided with a groove with an involute, flowing of thermoplastic metal is facilitated, and healing of the inner cracks can be promoted.
Owner:NORTHWESTERN POLYTECHNICAL UNIV

Top grafting method of golden silk willows

The invention relates to the field of plant grafting, in particular to a top grafting method of golden silk willows. The method includes the eight steps of selecting, stock breaking, ear peeling, agent coating, stock peeling, stock cutting, agent applying and post-grafting management. By improving and innovating an existing grafting technology, the golden silk willows have advantages in height, shape and color, do not generate too many catkins and have a high survival rate after being grated to stand willows, the overall ornamental value is increased, the cultivation period is shortened, cultivation environment conditions are widened, and requirements of urban garden greening projects are rapidly met.
Owner:YIBIN YUNCHEN ARBOR GARDEN

Medical adhesive with healing promoting and repairing functions

InactiveCN108904870AResist pressureProtects against skin photodamageOrganic active ingredientsHydrolysed protein ingredientsAdhesiveMicrosphere
The invention discloses a medical adhesive with healing promoting and repairing functions. The medical adhesive is characterized by comprising the components, by weight, 20-25 parts of a-butylcyanoacrylate, 25-35 parts of a-isoctyl cyanoacrylate, 2-6 parts of styrene class thermoplastic elastomer microspheres, 25-37 parts of effective healing promoting and repairing components, 2-4 parts of sodiumalginate, 3-6 parts of sodium hyaluronate, 8-10 parts of allantoin, 1 part of hydrolyzed wheat protein, 1 part of stabilizer, 150-220 pats of compound fruit oil components and 200 parts of aquae sterilisata. The medical adhesive specially selects a variety of biological extracts with regenerative functions and adds three components of healing promoting and repairing components to promote healingand improve the repairing effect, has high bonding strength and good biocompatibility, and meets the clinical application requirements for medical adhesive.
Owner:浙江派菲特新材料科技有限公司

Intestinal probiotics and application thereof in treating tumors and replacing antibiotics

The invention discloses intestinal probiotics and application thereof in treating tumors and replacing antibiotics. The lactobacillus reuteri JMR-01 provided by the invention has the preservation number of CGMCC No. 21304. The invention also provides a complex microbial inoculant of the complex microbial inoculant and the following application of the complex microbial inoculant: 1) treatment and / or prevention of tumors; 2) inhibiting of tumor cell proliferation; 3) preventing or treating of diseases caused by pathogenic bacteria; 4) replacing of antibiotics; 5) inhibiting of proliferation of pathogenic bacteria; and 6) promoting or synergistical treating of tumors. The invention provides intestinal probiotics, a method for treating tumors based on the intestinal probiotics and improving the tumor treatment effect by assisting irradiation treatment, and a method for treating tumors by taking the intestinal probiotics as a raw material.
Owner:INST OF MODERN PHYSICS CHINESE ACADEMY OF SCI

Method for rapidly forming big tree by multi-point approach grafting of gingko seedlings, rapidly-formed big tree and application thereof

The invention provides a method for rapidly forming a big tree by multi-point approach grafting of gingko seedlings, a rapidly-formed big tree and an application thereof, relating to the technical field of landscape plant cultivation. The method comprises the following steps: forming the shape of the big tree with at least two young gingko seedlings aged from 2 to 5 years, removing barks of approach grafting parts of a gingko such that phloem is exposed and smearing a layer of healing agent to the exposed part; binding the young gingko seedlings such that the seedlings grow like the shape of the big tree; and culturing the young gingko seedlings for 1-2 months so that an approach grafting healing surface of trunks between the young gingko seedlings can be firmly healed. According to the conventional mode, a big tree is formed by grafting and winding methods. However, it always takes one growth season or one year without ensuring that the big tree is healed. The method helps notably increase healing efficiency. The adult big tree grows integrally so as to resist cold and heat. Ultimately, the tree is healed without four weeks due to modeling and grows quickly into the big tree. Therefore, the purpose of making landscape architecture is achieved.
Owner:NANJING FORESTRY UNIV

Ointment for treating acne and preparation method and application thereof

InactiveCN106539817ALess reactiveLess likely to cause side effectsAntibacterial agentsAntipyreticClinical efficacyVitamin C
The invention relates to an ointment, in particular to an ointment for treating acne and a preparation method and application thereof. The ointment for treating acne comprises a base material and active pharmaceutical ingredients, wherein the active pharmaceutical ingredients comprise 500-2000 parts of doxycycline hyclate, 800-2500 parts of chloramphenicol, 500-2000 parts of triamcinolone acetonide acetate, 500-2000 parts of vitamin C, 10-100 parts of glucocorticoid, 10-100 parts of vitamin B2 and 5-100 parts of cyproheptadine hydrochloride. The ointment for treating acne is unique in composition and significant in therapeutic effect; through the unique compatibility of the composition, various medicines in the active pharmaceutical ingredients not only can achieve effects of the original medicine but also can be further improved in clinical effect after being combined; sebum secretion is effectively regulated, toxins and hazardous substances in hair follicles are discharged, and symptoms such as acne and comedo can be eliminated fundamentally; and meanwhile the ointment has significant therapeutic effects on acne mark fading and acne pit smoothing.
Owner:杜光彦

Three-dimension-extending intramedullary nail

A three-dimension-extending intramedullary nail, which is made of memory metal, comprises a rod-shaped body, two distal ends formed at two ends of the rod-shaped body, and a plurality of bent portions on the rod-shaped body and between the two distal ends. Each of the bent portions is bent around a curve center and defines a reference plane whereon the bent portion and the curve center are disposed, and at least two of the reference planes of the bent portions are different. The three-dimension-extending intramedullary nail can be implanted into marrow cavity in one time and is applicable to the treatment of various fracture patients. In addition, the three-dimension-extending intramedullary nail is flexible and can be bent according to the curvature of the marrow cavity, thereby being applicable to the marrow cavity of different length. Moreover, the three-dimension-extending intramedullary nail can also form axial deformation to apply pressure upon fracture surface, thus to pull and pressure the fracture surface and promote bone regeneration and shorten fracture healing time.
Owner:METAL INDS RES & DEV CENT +1

Olefin metathesis for effective polymer healing via dynamic exchange of strong carbon-carbon bonds

A method of preparing a malleable and / or self-healing polymeric or composite material is provided. The method includes providing a polymeric or composite material comprising at least one alkene-containing polymer, combining the polymer with at least one homogeneous or heterogeneous transition metal olefin metathesis catalyst to form a polymeric or composite material, and performing an olefin metathesis reaction on the polymer so as to form reversible carbon-carbon double bonds in the polymer. Also provided is a method of healing a fractured surface of a polymeric material. The method includes bringing a fractured surface of a first polymeric material into contact with a second polymeric material, and performing an olefin metathesis reaction in the presence of a transition metal olefin metathesis catalyst such that the first polymeric material forms reversible carbon-carbon double bonds with the second polymeric material. Compositions comprising malleable and / or self-healing polymeric or composite material are also provided.
Owner:RGT UNIV OF CALIFORNIA

Adjustable orthopedic splint

The invention relates to an adjustable orthopedic splint, and belongs to the technical field of medical instruments. The adjustable orthopedic splint comprises a head fixed clamping seat, a splint fixed frame, a fixed splint, a foldable connection splint and a tail fixed clamping seat, a head frame fixed seat is arranged on the upper side of the head fixed clamping seat, a telescopic auxiliary frame is arranged on the right side of the splint fixed frame, a splint elasticity compression device is arranged matched with the upper surface of the splint fixed frame, a splint positioning hole is matched with the upper surface of the fixed splint, a telescopic clamping plat is arranged on the right side of the fixed splint, a spherical connection rotating shaft is arranged in the middle of the foldable connection splint, a tail frame fixed sleeve is arranged on the upper side of the tail fixed clamping seat, a tail seat connection rotating shaft is arranged on the right side of the tail fixed clamping seat, a tail seat fixed connector is arranged on the left side of the tail fixed clamping seat. The splint is simple and convenient to operate, time and labor are saved, rapid assembly anddisassembly can be achieved, fixed pressure and local fixed positions can be flexibly adjusted according to wounded areas, the healing efficiency of a patient can be improved, and working difficulty of medical staff is relieved.
Owner:王海涛

High efficiency callus agent for promoting plant healing

The invention relates to the technical field of garden biological preparations, in particular to a high efficiency callus agent for promoting plant healing. The callus agent is prepared from the following components: chitosan quaternary ammonium salt, glycerol, gelatin, deionized water, a calcium carbonate medium, 2,4-D butyl ester, gibberellin, pimacol, potassium sorbate, vitamin, a chemical bacteriostat, ethanol, attapulgite clay, polyacrylamide and a tackifier. The calcium carbonate medium is lightweight porous calcium carbonate powder subjected to special treatment; the chemical bacteriostat is one or a mixture of any more of azoxystrobin, mildothane and prochloraz; the tackifier is acrylic polyurethane or vinyl acetate-vinyl copolymer emulsion. The callus agent contains a variety of plant hormones and bacteriocidal substances, and has high breathability and water retention, so that the healing effect of wounds is better and the healing speed is higher.
Owner:合肥市晨雷思建筑材料科技有限公司

Medical antibacterial dressing

The invention discloses a medical antibacterial dressing and belongs to a medical surgical wound care material. The fiber is supported with chlorite and an acidic material, and after plasma or body fluid infiltrates the fiber, the chlorite and the acidic material are dissolved and mixed in the infiltrated material, chlorine dioxide is released, and the fiber absorbs the wound exudate while achieving an antibacterial effect. Because the antibacterial component is supported on the fiber material, is convenient to store, good in water solubility, is very easily mixed with the infiltrated material, is stable in effect, achieves broad-spectrum sterilization and the antibacterial substance is gradually released with the increasing proportion of the infiltrated material to achieve the sustained release effect, so that the action time is further prolonged, the medical antibacterial dressing is especially suitable for chronic wounds such as ulcers and burns, and absorbs wound exudate while reducing the chance of wound infection.
Owner:QINGDAO ZHONGTENG BIOTECH

Preparation method of bioactive medical dressing

The invention discloses a preparation method of a bioactive medical dressing. The method comprises the following steps of S1, taking raw material solutions for later use, and performing printing through a microfluidic 3D printing assembly; and S2, introducing contents into all channels in a multi-channel coaxial jet head, controlling the flow speed, setting parameters of a 3D printer, and using the 3D printer to control a micro-fluidic chip to print the three-dimensional diabetic foot ulcer functional medical dressing, wherein the raw material solutions comprise an alginate solution, a first high-molecular polymer solution, a bioactive component solution and a second high-molecular polymer solution. According to the method, the process is simple, subsequent treatment of the dressing is not needed, the production efficiency is high, the cost is low, the product is stable, the precision is high, and the experimental repeatability is high.
Owner:WUYI UNIV

A kind of porous composite gel-nanofiber oxygen-permeable dressing and preparation method thereof

The invention discloses a porous complex gel-nanofiber oxygen permeation dressing and a preparation method thereof. The method comprises the following steps: obtaining a collagen nanofiber membrane by adopting a collagen solution by virtue of an electrostatic spinning method; performing chemical crosslinking on two natural and non-toxic macromolecule polysaccharides such as chitosan and alginic acid, and preparing complex gel; and preparing the porous sponge-nanofiber double-layer composite material in a freeze-drying mode, wherein the upper gel layer of the dressing is in a sponge state during drying and is in a gel state after moisture absorption. The biological wound dressing is prepared under the condition that any toxic chemical crosslinking agent is not added, the process is simple, and the safety is high. The prepared biological wound dressing disclosed by the invention has the characteristics of excellent oxygen permeation performance, water-absorbing quality, water permeability, moisture penetrability and high biocompatibility, a physiological wet environment of the wound surface can be maintained, wound healing and effective haemostasis are promoted, wound infection can be avoided, the recovery is accelerated, the wound surface can be effectively recovered, and the dressing is applied to multiple wound surfaces such as trauma, burns and ulceration.
Owner:FOURTH MILITARY MEDICAL UNIVERSITY

Multifunctional scenic area indication device capable of collecting garbage

The invention provides a multifunctional scenic area indication device capable of collecting garbage. The multifunctional scenic area indication device comprises a luminous plate and an isolation block. A base is of a circular cake-shaped structure. Two umbrella storage holes are formed in the top end face of a garbage can storage frame, and the bottom of a supporting column is arranged on the topend face of the garbage can storage frame. A garbage can is of a cylindrical hollow structure, a garbage can top cover is arranged on the top of the garbage can, and a garbage collecting port is formed in the front end face of the garbage can top cover. Two umbrella hanging frames are arranged, and one end of each umbrella hanging frame is of a circular-ball-shaped structure. When rain suddenly happens in the scenic area, rain sheltering appliances can be provided for scenic area visitors, the situation that rain wets personnel clothes, and the later scenic area viewing effect of personnel isinfluenced is avoided; and in cooperation with the arrangement of umbrella storage grooves in the garbage can, umbrellas can be better stored and fixed, the area occupied by the umbrellas is reduced,and the situation that due to wind generated in the scenic area, the umbrellas are blown away from the device, and the later umbrella usage effect is influenced is avoided.
Owner:通慧达南京智能科技有限公司

Bridge self-repairing paving method based on cement-based composite material

The invention discloses a bridge self-repairing paving method based on a cement-based composite material. The method comprises the following steps: 1) preparing materials: respectively weighing cement, fly ash, rubber powder, quartz sand, polyvinyl alcohol fibers, a high efficiency water reducing agent and water; with the mass ratio of the fly ash to the cement being 2-2.5, and the particle size range of the rubber powder being 40-80 meshes; 2) preparing a test piece; 3) maintaining the test piece; 4) prefabricating cement-based composite material components; and 5) performing pavement: conveying a roller wound with the prefabricated cement-based composite material components to a bridge construction site, gradually releasing the prefabricated cement-based composite material components, and paving the components onto a bridge base layer or a bridge surface layer till pavement is completed. The method is high in construction efficiency, convenient to construct and low in construction cost.
Owner:维特国际新材料(武汉)有限公司

Network fault healing method, device and system

The invention provides a network fault healing method, device and system. The method is applied to the network fault healing system. The method comprises the steps that an equipment controller obtainsdata information from front-end equipment; the equipment controller sends the data information to an instruction adapter; the instruction adapter receives the data information and sends the data information to a self-healing device; the self-healing device receives the data information and processes the data information to obtain fault information; the self-healing device obtains a healing instruction from a healing template according to the fault information, and sends the healing instruction to the front-end equipment or a client; and the front-end equipment receives and executes the healing instruction so as to complete the fault healing, or the client displays the healing instruction so as to enable a user to perform a fault healing operation on the front-end equipment according to the healing instruction.
Owner:DATANG SOFTWARE TECH

Modified cellulose nanofiber membrane based on layer-by-layer self-assembly of lysozyme and silk protein based as well as preparation and application thereof

The invention discloses a modified cellulose nanofiber membrane based on layer-by-layer self-assembly of lysozyme and silk protein as well as preparation and application thereof and belongs to the technical fields of high polymer materials and biomedical materials. According to the invention, a cellulose acetate nanofiber membrane is prepared by utilizing an electrospinning technique and lysozyme and silk protein which are opposite in charges are alternately assembled on the surface of the cellulose nanofiber membrane by adopting a layer-by-layer assembly technique so as to obtain the modified cellulose nanofiber membrane disclosed by the invention. The membrane disclosed by the invention has the advantages that the preparation equipment is simple, raw materials are low in cost, non-toxic and biodegradable, the whole process is simple to operate and the number of lysozyme / silk protein layers is controllable. Proved by antibacterial tests, cell survival tests, cell fluorescence staining tests, cell adhesion tests and in vitro wound healing tests, the modified cellulose nanofiber membrane disclosed by the invention has good antibacterial performance and cell adhesiveness and is capable of increasing the wound healing efficiency and preventing the wound infection, so that the membrane is a very good wound repairing material and can be used in the wound repairing field.
Owner:HUBEI SAILUO BIOLOGICAL MATERIAL CO LTD

Antibacterial self-repairing hydrogel and preparation method thereof

The invention relates to an antibacterial self-repairing hydrogel and a preparation method thereof. According to the invention, the hydrogel is endowed with a self-repairing function by a physical crosslinking method based on a hydrophobic effect; the hydrogel is endowed with antibacterial properties and conductivity through introduction of choline-amino acid ionic liquid (VILs); and the tensile property and toughness of the hydrogel are enhanced by bacterial cellulose (BC) with good biocompatibility. The preparation method of the hydrogel comprises the following steps: (1) synthesis of choline-amino acid ionic liquid; (2) preparation of a vinyl choline-amino acid ionic liquid monomer (VILs); (3) purification and hydrolysis of bacterial cellulose; and (4) forming of the polycholine-amino acid ionic liquid self-repairing hydrogel. The hydrogel disclosed by the invention is high in self-healing efficiency, has good antibacterial property, mechanical property, conductivity and biocompatibility, and is applicable to the fields of biology, medical treatment and tissue engineering.
Owner:TIANJIN POLYTECHNIC UNIV

Platelet directional-release growth factor composition and preparation method thereof

InactiveCN110051692AAvoid mutual interferenceImprove treatment effectiveness and efficiencyAntibacterial agentsOrganic active ingredientsDiseaseGrowth factor
The invention discloses a platelet directional-release growth factor composition and a preparation method thereof, belongs to the field of disease treatment, and aims to provide a method for promotingplatelet directional release of different growth factors so as to achieve the purpose of efficiently treating different diseases. The technical scheme are as follows: the platelet directional-releasegrowth factor composition comprises a PAR thrombin receptor, autologous platelet-rich plasma and heparin; the preparation method comprises the following operation steps: S1, adding PAR and heparin into autologous platelet-rich plasma, and manually stirring and mixing to obtain a mixed solution; S2, incubating the mixed solution in S1, centrifuging, and taking the supernatant to obtain the composition. The platelet directional-release growth factor composition is suitable for enabling the platelets to directionally release the targeted growth factors according to different treatment requirements and eliminating the interference of other growth factors, thereby greatly improving the treatment efficiency of the platelet-rich plasma for different diseases and obtaining a better treatment effect.
Owner:NANJING FIRST HOSPITAL

Expansion pressurization band-aid/plaster and preparation method thereof

The invention discloses an expansion pressurization band-aid / plaster, which belongs to the technical field of medicine and health. According to the invention, a continuous compression hemostasis effect can be easily obtained after one-time pressurization, so operation is simple, use is convenient, hemostasis compression force is fully improved, and an effective hemostasis effect can be achieved on various wound surfaces and bleeding conditions. The invention further provides a preparation method of the expansion pressurization band-aid / plaster. According to the invention, graphene fibers used in the method have excellent broad-spectrum antibacterial and antiviral capacity, and a preparation process is simple; while the prepared band-aid / plaster can provide pressure continuously, better bacteriostasis and virus resistance can be achieved, and the healing efficiency of a wound is improved; and graphene nanoplatelets tightly cover the surfaces of the fibers, so the elastic strength of the fibers is improved, the graphene nanoplatelets are not easy to fall off, the risk of graphene falling off under the conditions of water, blood and other special solutions is greatly reduced, the band-aid / plaster is not easy to damage and prolonged in service life. The band-aid / plaster of the invention has obvious effect and is suitable for wide popularization.
Owner:QINGDAO UNIV
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