6results about How to "Improve healing efficiency" patented technology

The present application relates to the technical field of pulse electromagnetic field treatment, in particular to a pulse electromagnetic field treatment device and method for promoting fracture healing. According to the distribution characteristics of different inflammation parameter detection values, serum prealbumin concentration, core nutrient intake and fracture healing contribution of different days, the present application obtains the comprehensive effective nutrient supply amount of each day; according to the distribution characteristics of core nutrient intake, comprehensive effective nutrient supply amount and inflammation parameter detection value of different days between the current patient and different historical patients, the present application obtains the patient clustering cluster where the current patient is located; according to the change trend of bone metabolism marker detection value of each day of different historical patients in the patient clustering cluster where the current patient is located, the present application obtains the reference historical patient and the corresponding electromagnetic field treatment parameter. The present application accurately obtains the reference historical patient and the electromagnetic field treatment parameter, and improves the healing efficiency of pulse electromagnetic field treatment.

This utility model relates to the field of minimally invasive postoperative wound dressing technology, specifically a minimally invasive postoperative wound dressing with wound closure function. It includes an adhesive layer, release paper installed on both sides of the bottom of the adhesive layer, low-sensitivity adhesive tape evenly installed on both sides of the top of the adhesive layer, and a sterilization layer embedded in the middle of the adhesive layer. The improved minimally invasive postoperative wound dressing adds a first elastic band and a second elastic band. When the wound dressing is applied to the wound surface, the first and second elastic bands can be pulled to traction the sides of the adhesive layer, thereby effectively closing the wound, reducing the risk of wound dehiscence, and promoting rapid wound healing. An absorbent layer made of highly absorbent resin is also added, allowing the absorbent layer to quickly absorb tissue fluid exudated from the wound during the healing process, helping to reduce the risk of wound infection and thus promoting wound healing.

The invention relates to the technical field of biological medicine, in particular to controlled release exosome hydrogel as well as a preparation method and application thereof. Compared with an existing exosome delivery system, the controllable-release exosome hydrogel prepared by the preparation method of the controllable-release exosome hydrogel, provided by the invention, has the following remarkable advantages in the following aspects: 1, accurate space-time regulation and control can be realized; 2, the biological activity of the exosome can be improved; 3, the wound microenvironment can be adapted; 4, the functions of exosome treatment, photo-thermal antibiosis, hemostasis, angiogenesis promotion and the like are integrated; 5, the biocompatibility is excellent, and the cell survival rate is high; 6, animal experiment results show that the controlled release exosome hydrogel provided by the invention is helpful for promoting the healing of wounds; in a full-thickness skin defect and deep second-degree burn model, epithelialization and collagen deposition can be accelerated, so that scar formation is reduced. Therefore, the method is expected to be applied to preparation of wound repair products.

This invention discloses a film-forming hydrogel containing keratin 8 and its application in promoting the repair of fish surface injuries, belonging to the technical field of fish wound repair materials. The film-forming hydrogel containing keratin 8, by mass percentage, consists of 8.25% polyvinyl acetate, 4.5% polyethylene ester, 1.1% xanthan gum, 0.2% benzyl chloride, 0.9% phenoxyethanol, 0.1% ethylhexylglycerin, 0.5% propylene glycol, 7% mica, 1% titanium dioxide, 1.5%–3% keratin 8, and the balance being water. Experimental verification shows that the film-forming hydrogel provided by this invention can block bacterial diffusion; it can form a stable and barrier-like covering layer in an aquatic environment; and it can promote the repair of fish surface injuries, significantly improving healing efficiency. This invention provides a feasible solution for underwater repair of surface injuries in aquatic animals.

The utility model discloses a surgical nursing disinfection device, including the lamp stand, the lamp stand is equipped with the lamp stand and the connecting head, the both ends of lamp stand are all connected with connecting head, be equipped with the insertion cavity in connecting head, disinfection lamp subassembly, including two disinfection lamp groups and a plurality of guide board, two disinfection lamp group insertion respectively inserts into the insertion cavity of two connecting heads, the top of each disinfection lamp group all is equipped with a plurality of guide board, a plurality of guide board interval distribution in the length direction of disinfection lamp group, and guide board extends in the width direction of disinfection lamp group. The utility model discloses a surgical nursing disinfection device, it can install the lamp stand through the lamp stand, and the connecting head of lamp stand connects disinfection lamp group in the mode of insertion, with the guide board of disinfection lamp group top guiding guide light and exporting along the width direction, improve the irradiation surface of disinfection lamp group.

The invention discloses a compound of a basic fibroblast growth factor and a metal organic framework, a pharmaceutical composition and application, and belongs to the technical field of wound healing drugs. The bFGF (at) ZPF-2 compound provided by the invention comprises a metal organic framework material ZPF-2 and bFGF loaded on the ZPF-2, the bFGF (at) MIL-53 (Al)-FA compound provided by the invention comprises a metal organic framework material MIL-53 (Al)-FA and bFGF loaded on the MIL-53 (Al)-FA. By constructing two compounds of bFGF-coated ZPF-2 and bFGF-coated MIL-53 (Al)-FA, efficient loading and activity protection of bFGF are realized, rapid effect taking and continuous release synergy can be realized in response to a wound surface microenvironment, the biocompatibility is good, the wound surface healing effect is remarkably improved, and the storage and transportation cost is reduced.