72results about How to "Improve healing efficiency" patented technology

The invention discloses a modified cellulose nanofiber membrane based on layer-by-layer self-assembly of lysozyme and silk protein as well as preparation and application thereof and belongs to the technical fields of high polymer materials and biomedical materials. According to the invention, a cellulose acetate nanofiber membrane is prepared by utilizing an electrospinning technique and lysozyme and silk protein which are opposite in charges are alternately assembled on the surface of the cellulose nanofiber membrane by adopting a layer-by-layer assembly technique so as to obtain the modified cellulose nanofiber membrane disclosed by the invention. The membrane disclosed by the invention has the advantages that the preparation equipment is simple, raw materials are low in cost, non-toxic and biodegradable, the whole process is simple to operate and the number of lysozyme / silk protein layers is controllable. Proved by antibacterial tests, cell survival tests, cell fluorescence staining tests, cell adhesion tests and in vitro wound healing tests, the modified cellulose nanofiber membrane disclosed by the invention has good antibacterial performance and cell adhesiveness and is capable of increasing the wound healing efficiency and preventing the wound infection, so that the membrane is a very good wound repairing material and can be used in the wound repairing field.

The invention belongs to the technical field of a sensor, and provides a high-temperature thin film sensor with a self-healing composite protective layer and a preparation method thereof, and aims to realize miniaturization and thin-film application of the sensor. The thin film sensor is composed of a substrate, a thin film sensor sensitive functional layer and the self-healing composite protective layer, which are arranged from bottom to top in order, wherein the structure of the self-healing composite protective layer comprises YSiO / HfSiBCN periodic multilayer membrane structures from bottom to top in order, and the lowest layer and the topmost layer of the protective layer are both YSiO low-oxygen diffusion coefficient layers. The high-temperature thin film sensor adopts the self-healing composite protective layer with the self-healing composite protective layer, the YSiO low-oxygen diffusion coefficient layers and HfSiBCN self-healing layers are alternately deposited to form an anti-oxidative protection system with layers of protection, and therefore the thin film sensor can work for a long time under the condition of high temperature of 600-1500DEG C and has the advantages of high temperature resistance, corrosion resistance, oxidation resistance, fast response, etc.

The invention discloses an ultraviolet self-healing polyamide material. The ultraviolet self-healing polyamide material is formed by compounding metal ions with a ligand polyamide through coordinationbonds, wherein the polyamide contains an azodipyridine structure; and a molar ratio of azodipyridine units in the polyamide to the metal ions is 1:(0.1-1). A preparation method of the ultraviolet self-healing polyamide material comprises the following steps: reacting azodipyridinecarboxylic acid with thionyl chloride under a 80 DEG C refluxing condition to synthesize azodipyridyl acyl chloride; synthesizing polyamide from the azodipyridinecarboxylic acid and long-chain diamine at room temperature under the catalysis of triethylamine with dichloromethane as a solvent; and stirring mixed solution of the obtained dichloromethane solution of the polyamide containing the azodipyridine structure and a methanol solution of a metal salt at room temperature for 24 h, and then heating the obtainedsolution to remove the organic solvent in order to obtain the ultraviolet self-healing polyamide material. The self-healing polyamide material can be rapidly self-healed through the reversible metal coordination bonds under the irradiation of ultraviolet light, and the healing efficiency is close to 100%.

The invention discloses a high-strength aluminum alloy sheet resistance spot welding molten core inner crack healing method. The method is used for solving the technical problem that an existing resistance spot welding molten core inner crack healing method is poor in efficiency. According to the technical scheme, the mode that an upper shaft shoulder and a lower shaft shoulder rotate and rub synchronously to generate heat is adopted, double-faced synchronous healing processing is conducted on the same molten core inner crack on an upper face and a lower face of a spot welding joint, compared with healing processing sequentially conducted on faces separately, the friction residence time can be shortened, and healing efficiency is improved; according to the characteristic that a high-strength sheet aluminum alloy spot welding structure piece is poor in deformation resistance, through self-supporting functions of the upper shaft shoulder and the lower shaft shoulder, no base plate is needed, and healing of mass molten core inner cracks of large sheet multi-point spot welding structure pieces can be achieved; the friction face of a healing tool is provided with a groove with an involute, flowing of thermoplastic metal is facilitated, and healing of the inner cracks can be promoted.

A three-dimension-extending intramedullary nail, which is made of memory metal, comprises a rod-shaped body, two distal ends formed at two ends of the rod-shaped body, and a plurality of bent portions on the rod-shaped body and between the two distal ends. Each of the bent portions is bent around a curve center and defines a reference plane whereon the bent portion and the curve center are disposed, and at least two of the reference planes of the bent portions are different. The three-dimension-extending intramedullary nail can be implanted into marrow cavity in one time and is applicable to the treatment of various fracture patients. In addition, the three-dimension-extending intramedullary nail is flexible and can be bent according to the curvature of the marrow cavity, thereby being applicable to the marrow cavity of different length. Moreover, the three-dimension-extending intramedullary nail can also form axial deformation to apply pressure upon fracture surface, thus to pull and pressure the fracture surface and promote bone regeneration and shorten fracture healing time.

The invention relates to an adjustable orthopedic splint, and belongs to the technical field of medical instruments. The adjustable orthopedic splint comprises a head fixed clamping seat, a splint fixed frame, a fixed splint, a foldable connection splint and a tail fixed clamping seat, a head frame fixed seat is arranged on the upper side of the head fixed clamping seat, a telescopic auxiliary frame is arranged on the right side of the splint fixed frame, a splint elasticity compression device is arranged matched with the upper surface of the splint fixed frame, a splint positioning hole is matched with the upper surface of the fixed splint, a telescopic clamping plat is arranged on the right side of the fixed splint, a spherical connection rotating shaft is arranged in the middle of the foldable connection splint, a tail frame fixed sleeve is arranged on the upper side of the tail fixed clamping seat, a tail seat connection rotating shaft is arranged on the right side of the tail fixed clamping seat, a tail seat fixed connector is arranged on the left side of the tail fixed clamping seat. The splint is simple and convenient to operate, time and labor are saved, rapid assembly anddisassembly can be achieved, fixed pressure and local fixed positions can be flexibly adjusted according to wounded areas, the healing efficiency of a patient can be improved, and working difficulty of medical staff is relieved.

A composition comprising thermoset polymer, shape memory polymer to facilitate macro scale damage closure, and a thermoplastic polymer for molecular scale healing is disclosed; the composition has the ability to resolve structural defects by a bio-mimetic close-then heal process. In use, the shape memory polymer serves to bring surfaces of a structural defect into approximation, whereafter use of the thermoplastic polymer for molecular scale healing allowed for movement of the thermoplastic polymer into the defect and thus obtain molecular scale healing. The thermoplastic can be fibers, particles or spheres which are used by heating to a level at or above the thermoplastic's melting point, then cooling of the composition below the melting temperature of the thermoplastic. Compositions of the invention have the ability to not only close macroscopic defects, but also to do so repeatedly even if another wound / damage occurs in a previously healed / repaired area.

The invention discloses a medical antibacterial dressing and belongs to a medical surgical wound care material. The fiber is supported with chlorite and an acidic material, and after plasma or body fluid infiltrates the fiber, the chlorite and the acidic material are dissolved and mixed in the infiltrated material, chlorine dioxide is released, and the fiber absorbs the wound exudate while achieving an antibacterial effect. Because the antibacterial component is supported on the fiber material, is convenient to store, good in water solubility, is very easily mixed with the infiltrated material, is stable in effect, achieves broad-spectrum sterilization and the antibacterial substance is gradually released with the increasing proportion of the infiltrated material to achieve the sustained release effect, so that the action time is further prolonged, the medical antibacterial dressing is especially suitable for chronic wounds such as ulcers and burns, and absorbs wound exudate while reducing the chance of wound infection.

The invention discloses a porous complex gel-nanofiber oxygen permeation dressing and a preparation method thereof. The method comprises the following steps: obtaining a collagen nanofiber membrane by adopting a collagen solution by virtue of an electrostatic spinning method; performing chemical crosslinking on two natural and non-toxic macromolecule polysaccharides such as chitosan and alginic acid, and preparing complex gel; and preparing the porous sponge-nanofiber double-layer composite material in a freeze-drying mode, wherein the upper gel layer of the dressing is in a sponge state during drying and is in a gel state after moisture absorption. The biological wound dressing is prepared under the condition that any toxic chemical crosslinking agent is not added, the process is simple, and the safety is high. The prepared biological wound dressing disclosed by the invention has the characteristics of excellent oxygen permeation performance, water-absorbing quality, water permeability, moisture penetrability and high biocompatibility, a physiological wet environment of the wound surface can be maintained, wound healing and effective haemostasis are promoted, wound infection can be avoided, the recovery is accelerated, the wound surface can be effectively recovered, and the dressing is applied to multiple wound surfaces such as trauma, burns and ulceration.

The invention provides a multifunctional scenic area indication device capable of collecting garbage. The multifunctional scenic area indication device comprises a luminous plate and an isolation block. A base is of a circular cake-shaped structure. Two umbrella storage holes are formed in the top end face of a garbage can storage frame, and the bottom of a supporting column is arranged on the topend face of the garbage can storage frame. A garbage can is of a cylindrical hollow structure, a garbage can top cover is arranged on the top of the garbage can, and a garbage collecting port is formed in the front end face of the garbage can top cover. Two umbrella hanging frames are arranged, and one end of each umbrella hanging frame is of a circular-ball-shaped structure. When rain suddenly happens in the scenic area, rain sheltering appliances can be provided for scenic area visitors, the situation that rain wets personnel clothes, and the later scenic area viewing effect of personnel isinfluenced is avoided; and in cooperation with the arrangement of umbrella storage grooves in the garbage can, umbrellas can be better stored and fixed, the area occupied by the umbrellas is reduced,and the situation that due to wind generated in the scenic area, the umbrellas are blown away from the device, and the later umbrella usage effect is influenced is avoided.

The invention discloses a modified cellulose nanofiber membrane based on layer-by-layer self-assembly of lysozyme and silk protein as well as preparation and application thereof and belongs to the technical fields of high polymer materials and biomedical materials. According to the invention, a cellulose acetate nanofiber membrane is prepared by utilizing an electrospinning technique and lysozyme and silk protein which are opposite in charges are alternately assembled on the surface of the cellulose nanofiber membrane by adopting a layer-by-layer assembly technique so as to obtain the modified cellulose nanofiber membrane disclosed by the invention. The membrane disclosed by the invention has the advantages that the preparation equipment is simple, raw materials are low in cost, non-toxic and biodegradable, the whole process is simple to operate and the number of lysozyme / silk protein layers is controllable. Proved by antibacterial tests, cell survival tests, cell fluorescence staining tests, cell adhesion tests and in vitro wound healing tests, the modified cellulose nanofiber membrane disclosed by the invention has good antibacterial performance and cell adhesiveness and is capable of increasing the wound healing efficiency and preventing the wound infection, so that the membrane is a very good wound repairing material and can be used in the wound repairing field.