Rat endotracheal intubation method and application

A technology of tracheal intubation and tracheal cannula, which is applied to the rat tracheal intubation method and its application field, can solve the problems of rat injury, error, trauma experiment results, etc., to avoid secondary trauma, improve efficiency, and eliminate local Effect of infection

Inactive Publication Date: 2017-05-31
GANSU UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to provide a rat tracheal intubation method, aiming to solve the problems of injury, trauma and error in experimental results to rats in the existing tracheal intubation method

Method used

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Embodiment Construction

[0031] In order to make the object, technical solution and advantages of the present invention more clear, the present invention will be further described in detail below in conjunction with the examples. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.

[0032] The invention discloses a rat tracheal intubation method, which comprises the following steps:

[0033] (1) Animals were reared conventionally, anesthetized with isoflurane inhalation using a table-top anesthesia machine for experimental animals, and after no pain response from tail clamping, the rats were fixed on the mouse board in the supine position, the limbs were fixed, and the head was fixed so that the head was slightly Lean back. The assistant used a rubber band to strangle the upper teeth of the rat, pulling it forward and downward, and strangled the lower teeth with another rubber band to pull it backward...

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Abstract

The invention discloses a rat endotracheal intubation method and application. The method mainly comprises the following steps that an anesthetic rat is placed on the back and fixed, the upper and lower jaws of the rat are opened, the rat's glottis is exposed by means of a laryngoscope, and a tracheal tube, which is 6 to 7cm long, is directly inserted into the trachea, namely the opening and closing part of the glottis, by means of the observation of the laryngoscope; a thin steel wire is inserted into the tracheal tube and a small section of water column is inected; the water column movement change in the tracheal tube is observed, if the water column doesn't move or is sprayed out or sucked in violently, it means that the tracheal tube is enters the esophagus, and intubation is needed again; if the water column in the tracheal tube moves up and down rhythmically along with the animal's breathing frequency, it means that the tracheal tube is inserted into the trachea. The method is used for endotracheal intubation under the conditions of rat trachea administration, rat administration and molding, and rat pulmonary function detection and the like, and the method has the advantages of being simple, speedy, free of injuries, high in molding and administration success rate, accurate in pulmonary function detection and the like.

Description

technical field [0001] The invention belongs to the technical field of tracheal intubation, in particular to a rat tracheal intubation method and its application. Background technique [0002] The rat tracheal intubation technique is commonly used in rat tracheal drug delivery, rat tracheal drug delivery modeling, rat pulmonary function measurement, and experimental research related to respiratory diseases. Tracheal intubation is required for rat-related model replication and rat lung function testing. The tracheal intubation technique directly affects the success rate of model replication and lung function testing, and is critical throughout the experiment. [0003] In the past, the methods of tracheal intubation were mostly blind intubation and tracheotomy. [0004] The blind insertion method is easy to insert into the esophagus, the success rate is low, and repeated trial insertion is required. It is easy to damage the pharynx of the rat, resulting in the secretion of a ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61D7/00A61D7/04
CPCA61D7/00A61D7/04
Inventor 蔺兴遥舒畅李雪燕吴国泰张艳霞刘永琦任远李金田
Owner GANSU UNIV OF CHINESE MEDICINE
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