A kind of medicine for treating hair loss and preparation method thereof
A medicine and technology for making Polygonum multiflorum, which is applied in the field of medicine for treating hair loss and its preparation, can solve problems such as easy adhesion and agglomeration, slow conduction speed, low drying efficiency, etc., to reduce daily dosage, reduce dosage, and improve compliance Effect
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[0031] A preparation method of a medicine for treating hair loss, the medicine is Yangxue Shengfa Capsules, the preparation method mainly comprising: Angelica, Notopterygium, Chuanxiong using supercritical CO 2 Extraction, supercritical extract using β-cyclodextrin inclusion; make Polygonum multiflorum, Radix Paeoniae Alba, Gastrodia elata and supercritical CO 2 After the extracted medicinal residues are mixed, ultrasonic extraction is used, and the extract is concentrated in vacuum at low temperature to form the first thick paste; rehmannia glutinosa, papaya, and dodder are decocted in water, and the decoction is filtered and concentrated into the second thick paste; the above two After the thick paste is mixed evenly, it is dried under microwave vacuum at low temperature, and the obtained dry paste is pulverized, and after the prepared dry paste powder is mixed uniformly with the clathrate, an appropriate amount of auxiliary materials is added, granulated by dry method, and p...
Embodiment 1
[0051] A kind of medicine for treating alopecia, its preparation method is as follows: take by weighing 1050g of angelica, 410g of notopterygium, 410g of chuanxiong, adopt supercritical CO 2 Extraction, the extraction conditions are: extraction pressure 25Mpa, extraction temperature 50°C, analysis pressure 7Mpa, analysis temperature 40°C, extraction time 2 hours, to obtain 65g fat-soluble extract A and 1737g medicinal residue B; 205g, 1050g of Radix Paeoniae Alba, mixed with the remaining medicinal residue B of supercritical extraction, add 8 times the volume fraction of 65% ethanol solution for ultrasonic extraction twice, the first time for 2 hours, the second time for 1.5 hours, combine the alcohol extracts, filter After filtration, the filtrate was concentrated under reduced pressure (temperature 55° C.) to obtain 2455 g thick paste C, with a relative water density of 1.28 (50° C.); weigh 2050 g rehmannia glutinosa, 615 g papaya, and 1050 g dodder seed, add 10 times the amo...
Embodiment 2
[0053] A kind of medicine for treating alopecia, its preparation method is as follows: take by weighing 2100g of angelica, 820g of notopterygium, 820g of chuanxiong, adopt supercritical CO 2 Extraction, the extraction conditions are: extraction pressure 20Mpa, extraction temperature 60°C, analysis pressure 8Mpa, analysis temperature 50°C, extraction time 3 hours, to obtain 125g fat-soluble extract A and 3503g medicinal residue B; 410g, 2100g of Radix Paeoniae Alba, mixed with the residue B of supercritical extraction, add 7 times the volume fraction of 50% ethanol solution and ultrasonically extract 3 times, the first time is 1.5 hours, the second time is 1.5 hours, the third time is 1 hour , combined the alcohol extracts, filtered, and the filtrate was concentrated under reduced pressure (temperature 50°C) to obtain 4822g of thick paste C, with a relative density of 1.29 (50°C); weigh 4090g rehmannia glutinosa, 1230g papaya, and 2100g dodder seed, and add 12 times the amount ...
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