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Modular liquid handling system

A liquid handling, modular technology, applied in sampling, instruments, measuring devices, etc., can solve the problems of time-consuming, labor-intensive, and limited

Inactive Publication Date: 2018-06-08
COUNSYL INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Multiple operations involving different liquids or different processing steps, such as dispensing and pumping liquids and detecting target molecules, require the use of different devices, which is time-consuming and labor-intensive
Additionally, previously known automated sample processing systems are often limited to specific protocols, with little ability to quickly swap extraction chemistries or change processing steps to suit a particular laboratory's needs
[0006] Previously known manual or automated sample handling systems also generate large volumes of solid or liquid waste, such as used pipette tips or blood extracts, which must be done at great expense and risk exposing workers to large volumes of hazardous waste alone process or dispose of

Method used

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Embodiment Construction

[0059] Integrated Modular System

[0060] Integrated modular liquid handling systems and methods of using such systems are described. These systems can be used, for example, to perform assays, purify and / or isolate compounds and / or process samples in sample processing plates containing multiple wells or in sample tubes in test tube racks. Components of such modular liquid handling systems are also described, including sample transfer modules, liquid dispensing modules, liquid aspiration modules, modules for sensing parameters of the liquid such as liquid level and / or temperature, modules for detecting signals Modules and modules for magnetically attracting magnetic materials such as beads in wells of a sample processing plate or in sample tubes. The integrated modular liquid handling systems described herein can also perform various functions on liquid, eg, in wells of a plate or in sample tubes, eg, shaking, mixing, incubating a sample, and / or separating components of the sa...

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Abstract

Integrated modular liquid handling systems are described. The modular liquid handling systems may be customized for use in a variety of applications, including sample processing, assays, diagnostic analyses, and separation of biomolecules. The liquid handling systems may include a variety of integrated modules that provide functions including dispensing of liquids, aspiration of liquids, sensing of liquid parameters, and detection of signals.

Description

[0001] Cross References to Related Applications [0002] This application claims the benefit of US Provisional Application No. 62 / 203,358, filed August 10, 2015, and Application No. 62 / 218,463, filed September 14, 2015, which are hereby incorporated by reference in their entirety. technical field [0003] The present invention relates to the field of liquid handling, in particular liquid handling systems and methods for processing samples, detecting substances in samples and / or performing assays. Background technique [0004] Research or diagnostic laboratories typically process biological samples to extract target molecules, such as proteins or DNA, for subsequent research or diagnostic purposes, or to detect substances of interest in the samples. Consistent sample processing or diagnostic assays require long hours of labor by trained technicians or use of previously known sample processing systems that have low sample throughput and require use when assays or other procedu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N35/10G01N1/00G01N1/28G01N35/00G01N35/02G01N35/04
CPCG01N35/1065G01N2035/0418G01N35/026G01N35/0099G01N35/10G01N35/00584
Inventor K.拉帕姆T.H.金C.布雷姆纳
Owner COUNSYL INC
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