Quinoline quaternary ammonium salt compound and its preparation method and application
A technology for quaternary ammonium salts and compounds, applied in the field of quinoline quaternary ammonium salts and their preparation, can solve problems such as affecting oilfield production and exploitation, inability to operate normally, and increasing water treatment costs, and achieve good killing and inhibiting effects , good bactericidal and bacteriostatic function, excellent corrosion inhibition effect
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[0027] The second aspect of the present invention provides a kind of preparation method of quinoline quaternary ammonium salt compound, the method comprises: under the quaternization reaction condition, in organic solvent, the compound shown in formula (2) and formula (3) The shown compound carries out quaternization reaction, thereby obtains the compound shown in formula (1);
[0028] Formula (3) X-R 1 -X;
[0029] Among them, A is -O-(CH 2 CH 2 O) n -R 2 , n is an integer above 1, R 2 is H or C1-C6 alkyl; R is H or C1-C10 alkyl; R 1 C1-C10 alkylene, -L 1 -O-L 2 -, -(CH 2 CH 2 O) m -L 3 -or-(CH 2 O) m -L 4 -, where L 1 , L 2 , L 3 and L 4 Each is independently selected from C1-C6 alkylene groups, m is an integer of 2 or more; X is halogen.
[0030] Wherein, the above-mentioned groups can be selected as described above, and the present invention will not repeat them here.
[0031] According to the present invention, specific examples of compounds represe...
preparation example 1
[0060] 19.2g 2-methyl-5-hydroxyquinoline (purchased from Tissier (Shanghai) Chemical Industry Development Co., Ltd.), catalyst (sodium hydroxide, 0.1 gram) joins in the reactor, closes the reactor, replaces with nitrogen The air in the kettle was stirred, and the temperature was raised to 120° C., and about 44 g of ethylene oxide was slowly pressed in, and then the reaction was continued for 2 hours. After cooling down, the product was terminated by oxalic acid, which was identified as a compound represented by formula (2), wherein the average n of the ethylene oxide repeating unit of the group A was about 8.
preparation example 2
[0062] 19.2g 4-methyl-7-hydroxyquinoline (purchased from Tissier (Shanghai) Chemical Industry Development Co., Ltd.), catalyst (sodium hydroxide, 0.1 gram) joins in the reactor, closes the reactor, replaces with nitrogen Air in the kettle, stirred, and the temperature was raised to 120° C., and about 88 g of ethylene oxide was slowly pressed in, and then the reaction was continued for 2 hours. After cooling down, the product was terminated by oxalic acid, which was identified as a compound represented by formula (2), wherein the average n of the ethylene oxide repeating unit of the group A was about 16.
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