Automatic sample injector

Abstract

The invention discloses an automatic sample injector which comprises a rack, and a driving unit, a sample injection part assembly, a tray mechanism and a needle washing mechanism are arranged on the rack. The sample injection part assembly comprises a sample injection needle, and the sample injection needle can move under the action of a driving unit; the tray mechanism comprises a tray body, the tray body is used for supporting a sample disc, the sample disc is provided with a plurality of concave cavities used for containing sample bottles, and the sample injection needles can pierce bottle plugs of the sample bottles to complete sample injection operation; and the needle washing mechanism is used for washing the sample injection needle. The sample injection needle cleaning device is reasonable in structure, good in sample injection needle cleaning effect and small in cleaning liquid consumption.

Description

Technical Field

[0001] The invention relates to the technical field of sample detection, in particular to an automatic sample injector. Background Art

[0002] A sampler is a device or apparatus used to introduce samples into analytical instruments. It is widely used in laboratories, especially in the fields of chemical analysis, biomedical research, and environmental monitoring. The sample needle is a slender needle-shaped tool used to introduce samples into analytical instruments. In order to avoid cross contamination and ensure the accuracy and repeatability of the analysis results, the sample needle needs to be cleaned. Existing automated cleaning operations often involve inserting the sample needle into a static cleaning solution, which will leave sample liquid residue on the sample needle after multiple cleanings. Flushing cleaning methods often use a large amount of cleaning solution and are costly. Summary of the invention

[0003] The present invention discloses an automatic sampler, which solves the technical problems of incomplete cleaning of the sample needle or high cleaning cost in the prior art, and has the technical effects of reasonable structure, good cleaning effect of the sample needle and small amount of cleaning liquid. The technical scheme adopted is as follows: An automatic sample injector comprises a frame, on which a driving unit, a sample injection unit assembly, a tray mechanism and a needle washing mechanism are arranged; The injection part assembly includes an injection needle, and the injection needle can be displaced under the action of a driving unit; The tray mechanism comprises a tray body, the tray body is used to support the sample tray, and the sample tray is provided with a plurality of concave cavities for accommodating sample bottles, and the injection needle can pierce the stopper of the sample bottle to complete the injection operation; The needle washing mechanism is fixed on the frame and includes a needle washing chamber for accommodating the injection needle and extending vertically. The needle washing chamber is respectively connected with a first interface and a second interface, and the inner wall surface of the needle washing chamber is designed so that the injection needle can be inserted into the needle washing chamber and can be sealed and abutted against the inner wall surface of the needle washing chamber, so that the first interface is connected with the inner cavity of the injection needle, and the second interface is connected with the interlayer cavity outside the injection needle, so as to facilitate the cleaning of the inner and outer wall surfaces of the injection needle.

[0004] Based on the above technical solution, the needle washing mechanism also includes a needle washing tube and a needle washing seat that are detachably connected up and down, and the needle washing tube and the needle washing seat together form a needle washing cavity. The first inlet is arranged on the needle washing seat and is connected to the needle washing cavity upward, and the second interface is arranged on the needle washing seat and is connected to the needle washing cavity laterally.

[0005] On the basis of the above technical solution, the needle washing tube is also formed with a drainage chamber parallel to the needle washing chamber, and the drainage chamber is connected with the upper part of the needle washing chamber through a drainage groove, so that the waste liquid in the interlayer cavity can be discharged through the drainage chamber; an annular liquid receiving groove surrounding the needle washing chamber is formed on the needle washing seat, and the outlet end of the drainage chamber is arranged above the annular liquid receiving groove, and the outlet end of the drainage chamber extends downward to form a conical boss.

[0006] On the basis of the above technical solution, the injection part assembly also includes a fixed seat, an identification module and a protection module. The injection needle is arranged on the fixed seat and can be displaced under the action of the driving unit. The identification module includes a first movable part and a detection part. The detection part is fixed on the fixed seat and displaced synchronously with the fixed seat. The first movable part is arranged on the fixed seat and is slidably connected to the fixed seat up and down. When the first movable part displaces downward and collides with the sample bottle or the sample tray, the first movable part displaces relative to the detection part, and the detection part can send a signal to the external controller; the protection module includes a second movable part that displaces synchronously with the injection needle. The injection needle is displaceably connected to the fixed seat up and down, and the resistance of the injection needle to the up and down displacement relative to the fixed seat is sufficient to overcome the resistance of the injection needle to pierce the bottle stopper of the sample bottle. When the injection needle displaces relative to the fixed seat, the second movable part is identified and the external controller receives a signal.

[0007] On the basis of the above technical solution, the detection part includes an injection optical coupler fixedly connected to the fixed seat, the first movable part includes an injection baffle and a guide column fixedly connected to the injection baffle, the guide column is slidably connected to the fixed seat, the guide column is downwardly connected to the bottle pressing seat, and a first compression spring is provided on the outer sleeve of the guide column between the fixed seat and the bottle pressing seat. When the bottle pressing seat moves downward and collides with the sample bottle or sample tray, the injection baffle is displaced relative to the injection optical coupler, and the injection optical coupler sends a signal to an external controller.

[0008] On the basis of the above technical solution, the protection module also includes a hollow cavity formed in the fixed seat, the injection needle passes through the hollow cavity and the injection needle jacket is provided with a second compression spring and a needle seat, the second compression spring abuts against the inner top surface of the hollow cavity upward, and the second compression spring can press the needle seat against the inner bottom surface of the hollow cavity downward, and the second compression spring is designed so that the second compression spring can overcome the resistance of the injection needle piercing the sample bottle stopper; an axial long hole for the second movable part to pass through is also provided on the side wall of the hollow cavity.

[0009] On the basis of the above technical solution, the needle washing mechanism also includes a needle seat bracket fixed on the frame and a pressure sensor arranged under the needle washing seat. The needle seat bracket is arranged above the needle washing tube and is formed with an injection needle avoidance hole. When the injection needle passes through the avoidance hole and extends into the needle washing chamber and abuts against the seal of the needle washing chamber, the pressure bottle seat is pressed against the needle seat bracket, so that the pressure sensor monitors the pressing force when the injection needle abuts against the seal of the needle washing chamber.

[0010] On the basis of the above technical solution, a plurality of second detection members are provided on the tray body, and the plurality of second detection members can respectively identify the second identification members provided on the sample tray and send signals to the external controller to identify the sample tray.

[0011] Based on the above technical solution, the tray body is provided with a groove for accommodating the sample tray, and multiple second detection parts are arranged on the groove wall of the groove; the tray body is provided with a groove for accommodating the sample tray, and multiple second detection parts are arranged on the groove wall of the groove.

[0012] On the basis of the above technical solution, the frame includes a number of vertical plates, which enclose the injection part assembly, the tray mechanism and the needle washing mechanism in a relatively independent chamber. A cleaning bucket for accommodating cleaning liquid is provided outside the chamber to provide cleaning liquid to the cleaning mechanism, and a waste liquid tank is also provided outside the chamber. A liquid level sensor is provided at the waste liquid tank, and the liquid level sensor can send a signal to an external controller. The waste liquid discharged from the injector can be gathered in the waste liquid tank and then discharged outward.

[0013] Beneficial Effects The present invention has a reasonable structure. When the injection needle is inserted into the needle washing chamber, the needle washing chamber can be divided into two independent chambers. The two chambers are respectively connected to the first interface and the second interface, so that the inner and outer wall surfaces of the injection needle can be cleaned independently. The interlayer cavity formed by the injection needle and the inner wall surface of the needle washing chamber can conveniently inject cleaning liquid into the interlayer cavity to clean the outer wall surface of the injection needle, which can not only ensure the cleaning effect, but also greatly reduce the amount of cleaning liquid and reduce the cleaning cost. In addition, the inner and outer wall surfaces of the injection needle in the present application are cleaned independently, and the inner and outer wall surfaces of the injection needle can be cleaned at the same time, which can greatly improve the cleaning efficiency, and thus is conducive to improving the sample detection efficiency.

[0014] The needle washing tube and the needle washing seat are detachably connected and enclosed to form a needle washing chamber, which is convenient for thoroughly cleaning the needle washing chamber, further reducing cross contamination and improving the accuracy and repeatability of the test results. The first interface and the second interface are formed on the needle washing seat, which provides conditions for the cleaning liquid in the interlayer cavity to flow in opposite directions to the cleaning liquid in the injection needle. When the cleaning liquid in the interlayer cavity and the injection needle flow in opposite directions, the vibration of the injection needle caused by the flow of the cleaning liquid can be effectively offset, which is beneficial to improving the stability of the injection needle. The present application is flexible to use. When the injection needle is sealed against the needle washing chamber, the injection needle and the flow path connected to the injection needle can be used as a quantitative loop, effectively simplifying the configuration of the injection system.

[0015] In the present invention, the injection part assembly includes an identification module and a protection module. When working, the fixed seat is displaced downward by a set distance. When the first movable member conflicts with the sample bottle or the sample tray, the detection member sends a signal to the external controller, so that it can be identified whether the sample bottle is missing or the position is deviated, and an alarm signal is issued in time to avoid the situation that the injection needle is empty and missed. At the same time, the injection needle can be prevented from further movement, which is beneficial to improving the detection efficiency. The setting of the second compression spring makes the injection needle work normally and pierce the sample bottle stopper without deformation. When the injection needle mistakenly pierces the hard surface, the second movable member is displaced relative to the fixed seat, and the detection member sends a signal to the external controller, so that the injection needle can be effectively protected and the service life of the injection needle can be improved. In addition, both the first movable member and the second movable member can be identified by the detection member, making the structure more compact and conducive to reducing production costs. In addition, when cleaning the injection needle, the pressing seat can be downwardly abutted with the needle seat bracket in the needle washing mechanism, which can avoid the injection part assembly except the injection needle from applying force in the cleaning chamber, which is beneficial to improving the service life and sealing reliability of the cleaning mechanism. In addition, a pressure sensor is provided under the needle washing seat to monitor the pressing force when the injection needle abuts against the needle washing chamber seal, which facilitates automatic control.

[0016] In the present invention, the tray body includes a plurality of second detection members, and a second identification member is provided at a corresponding position of the sample tray. When the second detection member identifies the second identification member, a signal can be sent to the controller, and the controller can judge the specification of the sample tray accordingly, and the controller can control the switching of the default parameters of the injection system. There are multiple second detection members and second identification members, and sample trays of various specifications can be defined and identified by the arrangement and combination of the identification signals. It is convenient and flexible to use, and can greatly reduce production failures or losses caused by human negligence, and the automatic switching of the default parameters of the injection system is also conducive to improving production efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the prior art descriptions are briefly introduced below. Obviously, the drawings described below are only one embodiment of the present invention, and for ordinary technicians in this field, other implementation drawings can be derived from the provided drawings without creative work.

[0018] Figure 1 : A schematic diagram of the three-dimensional structure of the present invention after removing part of the frame; Figure 2 : Schematic diagram of the three-dimensional structure of the injection unit assembly; Figure 3 : A schematic diagram of the three-dimensional structure of the first movable member; Figure 4 : Schematic diagram of the three-dimensional structure after the injection needle and the protection module are assembled; Figure 5 : Schematic diagram of the three-dimensional structure of the fixed seat; Figure 6 : Figure 5 A schematic diagram of the cross-sectional structure of the front view of the middle fixing seat; Figure 7 : Schematic diagram of the three-dimensional structure of the sample tray on the tray mechanism Figure 1 ; Figure 8 : Schematic diagram of the three-dimensional structure of the sample tray on the tray mechanism Figure 1 ; Fig. 9 :Schematic diagram of the three-dimensional structure of the sample plate Figure 1 ; Fig.10 :Schematic diagram of the three-dimensional structure of the sample plate Figure 2 ; Fig.11 : A schematic diagram of the three-dimensional structure of the present invention; Fig.12 : A schematic diagram of the three-dimensional structure of the first movable member; Fig.13 : Schematic diagram of the three-dimensional structure after the injection needle and the protection module are assembled; Fig.14 : Schematic diagram of the three-dimensional structure of the fixed seat; Fig.15 : Fig.14 A schematic diagram of the cross-sectional structure of the front view of the middle fixing seat; DETAILED DESCRIPTION The following description and accompanying drawings fully illustrate the specific embodiments of this article so that those skilled in the art can practice them. Parts and features of some embodiments may be included in or replace parts and features of other embodiments. The scope of the embodiments of this article includes the entire scope of the claims, as well as all available equivalents of the claims. Herein, the terms "first", "second", etc. are only used to distinguish one element from another, without requiring or implying any actual relationship or order between these elements. In fact, the first element can also be called the second element, and vice versa. Moreover, the terms "include", "comprise" or any other variant thereof are intended to cover non-exclusive inclusion, so that the structure, device or equipment including a series of elements includes not only those elements, but also other elements that are not explicitly listed, or also include elements inherent to such structure, device or equipment. In the absence of more restrictions, the elements defined by the sentence "including one..." do not exclude the existence of other identical elements in the structure, device or equipment including the elements. Each embodiment is described in a progressive manner herein, and each embodiment focuses on the differences from other embodiments, and the same and similar parts between the embodiments can be referred to each other.

[0019] The terms "longitudinal", "lateral", "upper", "lower", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc. in this document indicate the orientation or position relationship based on the orientation or position relationship shown in the drawings, and are only for the convenience of describing this document and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operate in a specific orientation, and therefore cannot be understood as a limitation on the present invention. In the description of this document, unless otherwise specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a mechanical connection or an electrical connection, it can also be the internal communication of two elements, it can be a direct connection, or it can be an indirect connection through an intermediate medium. For ordinary technicians in this field, the specific meanings of the above terms can be understood according to specific circumstances.

[0020] As used herein, unless otherwise specified, the term "plurality" means two or more than two.

[0021] In this document, the character " / " indicates that the preceding and following objects are in an "or" relationship. For example, A / B means: A or B.

[0022] In this article, the term "and / or" is a description of the association relationship between objects, indicating that three relationships may exist. For example, A and / or B means: A or B, or, A and B.

[0023] like Figures 1 to 3An automatic sample injector shown includes a frame on which a driving unit, a sample injection assembly, a tray mechanism and a needle washing mechanism are arranged; The frame includes several vertical plates, which enclose the sample injection assembly, the tray mechanism and the needle washing mechanism in a relatively independent chamber. A cleaning bucket containing cleaning liquid is provided outside the chamber to provide cleaning liquid for the cleaning mechanism, and a waste liquid tank is also provided outside the chamber. A liquid level sensor is provided at the waste liquid tank. The liquid level sensor is a prior art and will not be described here. The liquid level sensor can send a signal to an external controller to monitor the liquid level information in the waste liquid tank in real time. In addition, in the present application, the waste liquid discharged by the sample injector can be collected in the waste liquid tank and then discharged outward.

[0024] like Figure 2 As shown, the injection part assembly includes a fixed seat 31, an injection needle 32, an identification module 33 and a protection module 34, and the injection part assembly can be displaced under the action of a driving unit; in this embodiment, the driving unit includes a first slide, a first motor, a crossbeam, a second slide, a second motor, a vertical rod and a third motor, the first slide is slidably connected to the frame forward and backward, the first motor is fixed on the frame and can drive the first slide to slide forward and backward, the crossbeam is fixed to the first slide, the second slide is slidably connected to the crossbeam left and right, the second motor is fixed on the crossbeam and can drive the second slide to slide left and right, the vertical rod is fixed to the second slide, the fixed seat is slidably connected to the fixed seat up and down, the third motor is fixed on the vertical rod and can drive the fixed seat 31 to slide up and down, so that the driving unit can drive the injection part assembly to move.

[0025] like Figure 2 As shown, The identification module 33 includes a first movable member 331 and a detection member 332. In this embodiment, the detection member 332 includes an injection optical coupler fixedly connected to the fixing seat 31, so that the injection optical coupler can be synchronously displaced with the fixing seat 31. Figure 2 As shown, the sample injection optical coupler is arranged facing the side of the fixing seat 31; The first movable member 331 includes a sample injection baffle 3311, a guide post 3312 fixedly connected to the sample injection baffle 3311, and a bottle pressing seat 3313. Figure 3 As shown, the guide post 3312 passes through the fixed seat 31 and is in clearance with the fixed seat 31, so that the guide post 3312 is slidably connected to the fixed seat 31, and the guide post 3312 is fixedly connected to the bottle pressing seat 3313 downward, and the bottle pressing seat 3313 is provided with a sampling needle avoidance hole, and the avoidance hole includes a guiding cone surface to guide the sampling needle 32 to pass through the bottle pressing seat 3313 from top to bottom. In addition, the guide post 3312 between the fixed seat 31 and the bottle pressing seat 3313 is provided with a first compression spring 3314; Figure 2As shown, there are two guide posts 3312 symmetrically arranged on both sides of the injection needle 32, a horizontal plate 33315 spans across the two guide posts 3312 and is fixedly connected to the top of the guide posts 3312, and the end of the horizontal plate 33315 is fixedly connected to the injection baffle 3311. Among them, the first compression spring 3314 is provided so that when the bottle pressing seat 3313 does not abut against the sample bottle or the sample tray, the horizontal plate 33315 abuts against the fixed seat downward to position the guide post 3312. When the bottle pressing seat 3313 abuts against the sample bottle or the sample tray, it can play a buffering role, so that the guide post 3312 can be smoothly displaced up and down, and the guide post 3312 can be prevented from jumping up and down under the action of inertia.

[0026] Preferably, under normal working conditions, the sample bottle is placed at the target position, and the fixed seat 31 drives the sample blocking piece 3311 and the guide post 3312 to synchronously move downward by a distance A1, during which the sample injection optical coupler always recognizes the sample injection blocking piece 3311; when the fixed seat continues to move downward by a distance A2, the bottle pressing seat 3313 abuts against the sample bottle stopper and compresses the first compression spring 3314, and the guide post 3312 drives the sample injection blocking piece 3311 to move upward relative to the fixed seat 31, that is, the sample injection blocking piece 3311 is separated from the sample injection optical coupler, and at this time the sample injection optical coupler sends a signal to the external controller; When the sample bottle at the target position is missing or deviated, the fixing seat 31 moves downward by a distance A1 and then continues to move downward by a distance A2. At this time, the injection optical coupler still recognizes the injection baffle 3311. The external controller can determine that the sample bottle is missing or deviated, and then send out an alarm signal, thereby avoiding the situation where the injection needle 32 is sucked empty and avoiding missed detection.

[0027] like Figure 4 As shown, the protection module 34 includes a second movable member 341 that moves synchronously with the injection needle 32, and a hollow cavity 342 formed in the fixing seat 31. Figure 5 and 6 As shown, the hollow cavity 342 extends vertically and is coaxial with the injection needle 32. The injection needle 32 passes through the hollow cavity 342 and the injection needle jacket is provided with a second compression spring 343 and a needle seat 344. The needle seat 344 is annularly fixed outside the injection needle 32. The second compression spring 343 abuts against the inner top surface of the hollow cavity 342 upward, and the second compression spring 343 can press the needle seat 344 against the inner bottom surface of the hollow cavity 342 downward. In this way, the injection needle 32 is connected to the fixed seat 31 in an upwardly displaceable manner.

[0028] In this embodiment, the second movable part 341 is a position sensor, which is a prior art and will not be described here. The second movable part 341 is laterally fixed to the outer wall surface of the injection needle 32, and the side wall forming the hollow cavity 342 is also provided with an axial long hole 311 for the second movable part 341 to pass through. In this embodiment, the second compression spring 343 is designed so that the second compression spring 343 can overcome the resistance of the injection needle 32 to pierce the stopper of the sample bottle without deformation; when the injection needle 32 contacts the hard surface downward under the fault condition, such as the sample plate, the inclined surface of the mouth of the sample bottle, etc., when the injection needle 32 moves upward relative to the fixed seat 31, the second movable part 341 moves upward to the injection optical coupler and is recognized by the injection optical coupler, and the injection optical coupler sends a signal to the external controller, and then sends an alarm signal, thereby simplifying the structure and reducing costs. In other embodiments of the present invention, a second detection member is also included, and the second detection member can identify the second movable part 341 and send a signal to the external controller.

[0029] like Figure 2 and 4 As shown, it also includes a pressure cover 35, and the hollow cavity 342 extends upward to form an upper opening on the fixed seat 31. The pressure cover 35 blocks the upper opening, and the bottom surface of the pressure cover 35 forms the inner top surface of the hollow cavity 342. In this embodiment, the pressure cover 35 is threadedly connected to the upper part of the hollow cavity 342, so that the degree to which the pressure cover 35 extends into the hollow cavity can be adjusted, and then the degree of compression of the second compression spring 343 can be adjusted. In this way, the maximum resistance that the second compression spring 343 can overcome to pierce the bottle stopper can be adjusted, which not only facilitates the processing and production of the fixed seat 31, but also is flexible in use.

[0030] When the sample bottle is placed at the target position and the injection needle 32 corresponds to the position of the sample bottle When the fixed seat 31 drives the sample injection baffle 3311 and the guide column 3312 to move downward by a distance A1 synchronously, the sample injection optical coupler always recognizes the sample injection baffle 3311; When the fixed seat 31 continues to move downward by a distance A2, the bottle pressing seat 3313 abuts against the sample bottle stopper and the injection needle 32 does not pierce the sample bottle stopper, and the first compression spring 3314 is further compressed. At this time, the guide column 3312 drives the injection baffle 3311 to move upward relative to the fixed seat 31, that is, the injection baffle 3311 is separated from the injection optical coupler, and the injection optical coupler sends a signal to the external controller; The fixed seat 31 continues to move downward by a distance A3, and the injection needle 32 and the second movable member 341 move synchronously, and the injection needle 32 pierces the stopper of the sample bottle and completes the injection operation.

[0031] When the sample bottle is placed at the target position, but the injection needle 32 does not correspond to the position of the sample bottle The working process in this case is different from that in the above case in that when the fixed seat 31 continues to move downward by a distance A3, the injection needle 32 abuts against a hard object other than the bottle stopper, and the injection needle 32 and the second movable part 341 move upward relative to the fixed seat 31, and the injection optical coupler recognizes the second movable part 341 and sends a signal to the external controller.

[0032] When the vial is missing at the target location When the fixing seat 31 continues to move downward by a distance A2, because the sample bottle is missing at the target position, the injection optical coupler still recognizes the injection baffle 3311, and the injection optical coupler does not send a signal to the external controller. The external controller then determines that the sample bottle is missing here and sends an alarm signal.

[0033] like Figure 7 and 8 As shown, the tray body 41 includes a tray body 41, which is used to support a sample tray 42. The tray body 41 is provided with a groove 411 for accommodating the supported sample tray 42, so as to facilitate the sample tray 42 to be placed on the tray body 41. In addition, the arrangement of the groove 411 can also position the sample tray 42 when the tray body 41 is displaced. The sample tray 42 is provided with a plurality of concave cavities 421 for accommodating sample bottles, and the bottom surface of the concave cavities 421 is provided with through holes to avoid liquid accumulation. The sample tray 43 is provided with an identifier for identifying the position of the concave cavity 421, so as to facilitate the positioning of any concave cavity 421.

[0034] The tray body 41 is provided with three second detection members 43 in parallel. Figure 7 As shown, the third second detection member 43 is arranged on the groove wall on one side of the groove 411. In this embodiment, the second detection member 43 includes a second optical coupler, and the corresponding position of the sample tray 42 includes an avoidance groove 422 corresponding to the second detection member 43, and at least one avoidance groove 422 is provided with a second identification member 44. In this application, the second identification member 44 includes a second baffle. When the second detection member 43 extends into the avoidance groove 422 and identifies the second identification member 44, the second detection member 43 sends a signal to the external controller to identify the sample tray 42, thereby controlling the default parameter switching of the injection system.

[0035] like Figure 8 As shown, the tray drive 45 is also included. The tray body 41 can slide along the axial direction of the tray body 41 under the action of the tray drive 45. The tray drive 45 includes a tray motor 451 and a screw transmission unit 452. The screw transmission unit 452 includes a screw and a screw nut matched with the screw. The tray motor 451 is fixedly arranged and can transmit the rotational motion to the screw. The screw nut is sleeved outside the screw and fixedly connected to the tray body upward. In this way, the tray motor 451 drives the tray body 41 to slide along its axial direction through the screw transmission unit 452. In this way, the tray drive 45 cooperates with the drive unit to quickly locate the sample bottle and the injection needle, which is conducive to improving the detection efficiency.

[0036] like Figure 8 As shown, it also includes a fixed support roller 46, the roller surface of the support roller 46 abuts against the bottom surface of the tray body 41 upward, and supports the tray body 41 upward; specifically, the end surface where the bottom surface of the tray body 41 abuts against the support roller 46 is an arc surface, and the arc surface is perpendicular to the axial direction of the support roller 46, so that the contact area between the two is small, which is not only beneficial to reduce friction, but also beneficial to reduce the difficulty of the processing technology of the contacting surfaces.

[0037] like Fig.11 As shown, the needle washing mechanism includes a needle washing tube 51 and a needle washing seat 52 which are detachably connected to each other. Specifically, an external thread is arranged at the lower part of the needle washing tube 51, and the needle washing seat 52 is arranged at an internal thread which matches the external thread. The bottom end surface of the needle washing tube 51 abuts against the shoulder on the needle washing seat 52 to achieve a sealed connection. Fig.13 As shown, the needle washing tube 51 and the needle washing seat 52 together enclose a vertically extending needle washing cavity 100 .

[0038] like Fig.13 and 14 As shown, the needle washing chamber 100 is respectively connected to a first interface 521 and a second interface 522, and the first interface 521 and the second interface 522 are respectively arranged on the needle washing seat 52, wherein the first interface 521 is arranged on the inner bottom surface of the needle washing chamber 100 and is coaxial with the needle washing chamber 100, and the second interface 522 is arranged above the first interface 521 and is laterally connected to the needle washing chamber 100. In other embodiments of the present invention, the second interface 522 extends along the tangential direction of the interlayer cavity and has an upward tilt angle, so that the introduced cleaning fluid can spirally rise to flush the outer wall surface of the injection needle 32, which is conducive to thorough cleaning. During the cleaning process, a stream of cleaning liquid can flow through the injection needle 32 and the first interface 521 under the action of the peristaltic pump and be discharged to clean the inner wall surface and pipeline of the injection needle 32, and another stream of cleaning liquid can flow through the second interface 522 and the interlayer cavity and be discharged to clean the outer wall surface of the injection needle 32. This provides conditions for the cleaning liquid in the interlayer cavity to flow in opposite directions to the cleaning liquid in the injection needle 32. When the cleaning liquid in the interlayer cavity and the cleaning liquid in the injection needle 32 flow in opposite directions, the vibration of the injection needle 32 caused by the flow of the cleaning liquid can be effectively offset, which is beneficial to improving the stability of the injection needle 32.

[0039] like Fig.14 and 15As shown, the injection needle 32 can vertically enter the needle washing chamber 100, and the inner wall surface of the needle washing chamber 100 is designed so that the injection needle 32 can be extended into the needle washing chamber 100 and can be sealed and abutted against the inner wall surface of the needle washing chamber 100, so that the first interface 521 is connected with the inner cavity of the injection needle 32, and the second interface 522 is connected with the interlayer cavity outside the injection needle 32, so that the inner and outer wall surfaces of the injection needle 32 can be easily cleaned. Specifically, the lower part of the needle washing chamber 100 includes a conical surface. In order to facilitate puncturing the stopper of the sample bottle, the lower part of the injection needle is provided with a conical surface, so that the outer wall surface of the injection needle 32 and the inner wall surface of the needle washing chamber 100 are sealed and abutted through the conical surface, as shown in FIG. Fig.15 shown.

[0040] Among them, the inner wall surface of the needle washing chamber 100 that is sealed against the outer wall surface of the injection needle 32 is made of plastic material, such as PEEK material, and the injection needle 32 is made of metal material, such as stainless steel. PEEK material has good corrosion resistance, sufficient structural strength and certain flexibility, and can achieve good sealing with the injection needle 32.

[0041] like Fig.13 and 14 As shown, a drainage chamber 200 parallel to the needle washing chamber 100 is also formed on one side of the needle washing tube 51. The drainage chamber 200 is connected to the upper part of the needle washing chamber 100 through the drainage groove 300, so that the waste liquid in the interlayer chamber can be discharged through the drainage chamber. Specifically, the inner bottom surface of the drainage groove 300 is an inclined surface, so that the waste liquid can smoothly slide from the needle washing chamber 100 into the drainage chamber 200 under the action of its own weight. In addition, the groove wall of the drainage groove 300 and the inner wall surface of the drainage chamber 200 have a smooth transition, and the drainage groove 300 gradually narrows along the flow direction of the waste liquid. In view of saving cleaning liquid, the interlayer chamber space in the present application is small, and the flow rate of waste liquid formed after cleaning is small. The setting of the drainage groove 300 in this embodiment not only enables the waste liquid to be discharged quickly, but also avoids the situation where the drainage is not complete due to the surface tension of the waste liquid droplets, and reduces the residual waste liquid.

[0042] like Fig.13 and 14 As shown, the needle washing seat 52 is formed with an annular liquid receiving groove 523 surrounding the needle washing cavity, the outlet end of the drainage cavity 200 is arranged above the annular liquid receiving groove 523, and the outlet end of the drainage cavity 200 extends downward to form a conical boss 400, so that the waste liquid can be prevented from adhering to the end surface of the outlet end, further reducing the waste liquid residue. The lower part of the liquid receiving groove 523 is also connected with a drainage pipeline 55 for discharging the collected waste liquid outward. In addition, the arrangement of the liquid receiving groove 523 and the drainage cavity 200 can replace the closed pipeline connection, which is convenient for the needle washing tube 51 and the needle washing seat 52 to be threadedly connected.

[0043] like Fig.11 and 12As shown, a needle seat bracket 54 is also fixedly arranged. The needle seat bracket 54 is arranged above the needle washing tube 51 and is formed with a sampling needle avoidance hole. The needle seat bracket 54 is used to support the sampling part assembly, so that when the sampling needle 32 is in sealing contact with the needle washing chamber 100, the force other than the sampling needle is applied to the conical surface of the needle washing chamber 100, which is beneficial to improve the service life of the needle washing chamber 100. A pressure sensor 53 is arranged below the needle washing seat 52. The pressure sensor 53 is used to monitor the pressing force applied by the sampling needle 32 on the conical surface of the needle washing chamber 100. When the monitored pressing force reaches the set range value, it indicates that the sampling needle 32 and the needle washing chamber 100 are sealed firmly.

[0044] The present invention is described above by way of examples, but the present invention is not limited to the above specific embodiments, and any changes or modifications made based on the present invention belong to the scope of protection claimed by the present invention.

Claims

1. An automatic sample injector, It is characterized in that It comprises a frame (1), on which a driving unit (2), a sample injection unit assembly (3), a tray mechanism (4) and a needle washing mechanism (5) are arranged; The injection part assembly (3) comprises an injection needle (32), and the injection needle (32) can be displaced under the action of the driving unit (2); The tray mechanism (4) comprises a tray body (41), the tray body (41) is used to support a sample tray (42), and the sample tray (42) is provided with a plurality of recessed cavities for accommodating sample bottles, and the injection needle (32) can pierce the stopper of the sample bottle to complete the injection operation; The needle washing mechanism (5) is fixedly mounted on the frame (1) and comprises a needle washing chamber (100) for accommodating the injection needle (32) and extending vertically. The needle washing chamber (100) is respectively connected to a first interface (521) and a second interface (522), and the inner wall surface of the needle washing chamber (100) is designed so that the injection needle (32) can be sealed and abutted against the inner wall surface of the needle washing chamber (100) when it is inserted into the needle washing chamber (100), so that the first interface (521) is connected to the inner cavity of the injection needle (32), and the second interface (522) is connected to the interlayer cavity outside the injection needle (32), so as to facilitate cleaning of the inner and outer wall surfaces of the injection needle (32).

2. The automatic sample injector according to claim 1, It is characterized in that The needle washing mechanism (5) further comprises a needle washing tube (51) and a needle washing seat (52) which are detachably connected to each other in an upper and lower manner; the needle washing tube (51) and the needle washing seat (52) together form a needle washing chamber (100); the first inlet (521) is arranged on the needle washing seat (52) and communicates with the needle washing chamber upward; and the second interface (522) is arranged on the needle washing seat (52) and communicates with the needle washing chamber (100) laterally.

3. The automatic sample injector according to claim 1, It is characterized in that The needle washing tube (51) is also formed with a drainage cavity (200) parallel to the needle washing cavity (100); the drainage cavity (200) is connected to the upper part of the needle washing cavity (100) through a drainage groove (300) so that waste liquid in the interlayer cavity can be discharged through the drainage cavity (200); an annular liquid receiving groove (523) surrounding the needle washing cavity (100) is formed on the needle washing seat (52); the outlet end of the drainage cavity (200) is arranged above the annular liquid receiving groove (523), and the outlet end of the drainage cavity (200) extends downward to form a conical boss (400).

4. The automatic sample injector according to any one of claims 1 to 3, It is characterized in that The injection portion assembly (3) further comprises a fixed seat (31), an identification module (33) and a protection module (34); the injection needle (32) is arranged on the fixed seat (31) and can be displaced under the action of the driving unit (2); the identification module (33) comprises a first movable member (331) and a detection member (332); the detection member (332) is fixedly arranged on the fixed seat (31) and displaces synchronously with the fixed seat (31); the first movable member (331) is arranged on the fixed seat (31) and is connected to the fixed seat (31) in a manner that it can slide up and down; when the first movable member (331) moves downward and abuts against the sample bottle or the sample tray (42), the detection member (332) can move upward and downward; When the first movable member (331) is touched, it is displaced relative to the detection member (332), and the detection member (332) can send a signal to the external controller; the protection module (34) comprises a second movable member (341) that is displaced synchronously with the injection needle (32), the injection needle (32) is connected to the fixed seat (31) in a manner that it can be displaced up and down, and the resistance of the injection needle (32) to the up and down displacement relative to the fixed seat (31) is sufficient to overcome the resistance of the injection needle (32) piercing the bottle stopper, when the injection needle (32) is displaced relative to the fixed seat (31), the second movable member (341) is identified and the external controller receives the signal.

5. The automatic sample injector according to claim 4, It is characterized in that The detection member (332) includes an injection optical coupler fixedly connected to the fixed seat (31), the first movable member (331) includes an injection baffle (3311) and a guide column (3312) fixedly connected to the injection baffle (3311), the guide column (3312) is slidably connected to the fixed seat (31), the guide column (3312) is downwardly connected to the bottle pressing seat (3313), and a first compression spring (3314) is provided on the outer sleeve of the guide column (3312) between the fixed seat (31) and the bottle pressing seat (3313), when the bottle pressing seat (3313) moves downward and contacts the sample bottle or the sample tray (42), the injection baffle (3311) moves relative to the injection optical coupler, and the injection optical coupler sends a signal to an external controller.

6. The automatic sample injector according to claim 5, It is characterized in that The protection module (34) further comprises a hollow cavity (342) formed in the fixing seat (31), the injection needle (32) passes through the hollow cavity (342), and the injection needle (32) is provided with a second compression spring (343) and a needle seat (344) on its outer sleeve, the second compression spring (343) abuts against the inner top surface of the hollow cavity (342) facing upward, and the second compression spring (343) can press the needle seat (344) against the inner bottom surface of the hollow cavity (342) facing downward, and the second compression spring (343) is designed so that the second compression spring (343) can overcome the resistance of the injection needle piercing the stopper of the sample bottle; an axial long hole (311) for the second movable member (341) to pass through is also provided on the side wall forming the hollow cavity (342).

7. The automatic sample injector according to claim 5 or 6, It is characterized in that The needle washing mechanism (5) further comprises a needle seat bracket fixedly mounted on the frame (1) and a pressure sensor (53) disposed below the needle washing seat (52); the needle seat bracket (54) is disposed above the needle washing tube (51) and is formed with an avoidance hole for the injection needle (32); when the injection needle passes through the avoidance hole and extends into the needle washing chamber and is in sealing contact with the needle washing chamber, the bottle pressing seat is pressed against the needle seat bracket (54), so that the pressure sensor (53) monitors the pressing force when the injection needle (32) is in sealing contact with the needle washing chamber (100).

8. The automatic sample injector according to claim 7, It is characterized in that The tray body (41) is provided with a plurality of second detection members (43), and the plurality of second detection members (43) can respectively identify a second identification member (44) provided on the sample tray (42) and send a signal to an external controller to identify the sample tray (42).

9. The automatic sample injector according to claim 8, It is characterized in that The tray body (41) is provided with a groove (411) for accommodating a supporting sample tray (42), and a plurality of the second detection components (43) are arranged on the groove wall of the groove (411); the tray body (41) is provided with a groove (411) for accommodating a supporting sample tray (42), and a plurality of the second detection components (43) are arranged on the groove wall of the groove (411).

10. The automatic sample injector according to claim 8 or 9, It is characterized in that The frame (1) comprises a plurality of vertical plates, wherein the vertical plates enclose the sample injection unit assembly (3), the tray mechanism (4) and the needle washing mechanism (5) in a relatively independent chamber, a cleaning bucket (6) containing a cleaning liquid is provided outside the chamber to provide the cleaning liquid for the cleaning mechanism, and a waste liquid tank (7) is provided outside the chamber, and a liquid level sensor is provided at the waste liquid tank (7), wherein the liquid level sensor can send a signal to an external controller, and the waste liquid discharged from the sample injector can be collected in the waste liquid tank (7) and then discharged to the outside.

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