Moisturizing and anti-aging micro-capsule composition for cosmetics and preparation method of moisturizing and anti-aging micro-capsule composition
By using soy lecithin, modified polystumin and other materials in cosmetics, prepare a microcarbon wall, and use the active extract as a cysts to form a flexible bead pill, which solves the existing moisturizing cosmetics cannot effectively solve the multiple factors of water loss of facial skin. The problem achieves better anti -wrinkle and moisturizing effects.
Patent Information
- Application Number
- CN202411696173.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-25
- Publication Date
- 2025-01-21
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
The moisturizing cosmetics present on the existing market cannot effectively solve the multiple factors of facial skin loss, resulting in poor moisturizing effect and cannot meet the market's demand for moisturizing durability and anti-aging.
Use soybean lecithin, modified polystumin, wrinkle corner fork dishes and calcium aldate as a component of microcarbon walls, combined with ciced grass extract, Baiwei extract, olive leaf extract, scutellaria baicalensis extract, and glycerin three three (Ethic acid) ester is used as a microcarbon core to form a flexible bead pill, and it is uniformly suspended in the decentralized substrate to form a moisturizing and anti -aging microcarin composition for cosmetics.
It significantly improves the anti-wrinkle and moisturizing effects of cosmetics, can quickly tighten the skin, smooth fine lines, and provide long-lasting moisturizing function to delay skin aging.
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Abstract
Description
Technical Field
[0001] The invention belongs to the technical field of cosmetics, and specifically relates to a moisturizing and anti-aging microcapsule composition for cosmetics and a preparation method thereof. Background Art
[0002] In today's society, with the improvement of people's living standards, people pay more and more attention to skin care and their own image. However, after reaching the age of 25, fine lines begin to appear between the corners of the eyes and eyebrows. Especially due to the rapid development of today's social economy, life pressure, irregular lifestyle, frequent computer or work pressure, etc., the facial skin becomes dry, rough, and lacks moisture, which in turn leads to reduced elasticity and skin atrophy and sagging. Therefore, how to achieve skin moisturizing and anti-aging has become a research hotspot in all walks of life.
[0003] Currently, there are cosmetics with moisturizing effects on the market, but their moisturizing mechanisms are single, and they do not take into account the multiple factors that lead to skin dehydration and the skin dehydration caused by skin damage. They cannot achieve comprehensive protection and do not have a good moisturizing effect. In addition, simple moisturizing can no longer meet the needs of the market. They have shortcomings such as poor moisturizing durability and single function. Therefore, the market urgently needs a product that has both moisturizing and anti-aging effects. Summary of the invention
[0004] In order to solve the deficiencies mentioned in the above-mentioned background technology, the purpose of the present invention is to provide a moisturizing and anti-aging microcapsule composition for cosmetics and a preparation method thereof, using soybean lecithin, modified polylactic acid, Chondrus crispus, and calcium alginate as microcapsule wall components, and active materials Centella asiatica extract, Olea europaea extract, Scutellaria baicalensis extract and triethylhexanoin as microcapsule cores, wrapping the active materials in the microcapsule wall to form flexible beads, and evenly suspending the flexible beads in a dispersed matrix, thereby giving the cosmetics better anti-wrinkle and moisturizing effects.
[0005] The purpose of the present invention can be achieved by the following technical solutions:
[0006] A moisturizing and anti-aging microcapsule composition for cosmetics comprises a dispersed matrix and flexible beads uniformly suspended in the dispersed matrix, wherein the flexible beads comprise active materials and microcapsule walls, wherein the active materials comprise Centella asiatica extract, Viburnum oleifera extract, Olive leaf extract, Scutellaria baicalensis extract, and glyceryl tri(ethylhexanoate), and the microcapsule walls comprise soybean lecithin, modified polylactic acid, Chondrus crispus, and calcium alginate, wherein the active materials are wrapped in the microcapsule walls, and the modified polylactic acid is prepared by grafting and modifying with L-arginine after graft copolymerization of chitosan and L-lactide in 1-butyl-3-methylimidazole chloride.
[0007] Preferably, according to the weight percentage in the microcapsule composition, the flexible beads include: 0.003-0.005% Centella asiatica extract, 0.003-0.005% Orchidaceae extract, 0.002-0.004% Olive leaf extract, 0.002-0.004% Scutellaria baicalensis extract, 15-20% triethylhexanoin, 2-5% soy lecithin, 2-4% modified polylactic acid, 0.1-1% Chondrus crispus, and 0.5-2% calcium alginate.
[0008] Preferably, in terms of weight percentage in the microcapsule composition, the dispersed matrix includes: 10-40% glycerol, 2-5% butylene glycol, 0.3-1% xanthan gum, 0.05-0.2% gellan gum, 0.5-1% 1,2-hexanediol, 0.23-0.8% p-hydroxyacetophenone, 0.1-1% trehalose, 0.3-0.8% agar, 0.1-0.5% hydroxyethyl cellulose, 0.01-0.05% disodium EDTA, 0.01-0.05% sodium hyaluronate, 0.003-0.01% soluble collagen, and 55-65% water.
[0009] Preferably, the preparation method of the modified polylactic acid comprises the following steps:
[0010] (1) 1-butyl-3-methylimidazole chloride is placed in a reactor, stirred at 75-85° C., chitosan is added, and stirred for 3-4 hours under a nitrogen atmosphere, and then L-lactide and stannous octoate are added to react for 10-12 hours. After the reaction is completed, isopropanol is added to terminate the reaction, and stirring is continued for 8-12 hours, and then filtered, washed, and dried to prepare functionalized polylactic acid;
[0011] (2) dissolving L-arginine, 1-ethyl-(3-dimethylaminopropyl)carbodiimide and N-hydroxysuccinimide in deionized water, placing in an ice water bath and stirring for 1 to 3 hours to activate the carboxyl groups, thereby preparing an activated arginine solution;
[0012] (3) Adding the functionalized polylactic acid to the activated arginine solution, mixing the mixture, and reacting the mixture at 30 to 50° C. for 20 to 24 hours. After the reaction is completed, filtering and drying are performed to obtain the modified polylactic acid.
[0013] Preferably, in the step (1), the addition ratio of 1-butyl-3-methylimidazole chloride, chitosan and L-lactide is 10-20 mL: 1 g: 4-6 g.
[0014] Preferably, the particle size of the flexible beads is 1 to 8 mm.
[0015] Preferably, the ratio of the diameter of the active material to the ring width of the microcapsule wall is 1:1-3.
[0016] The method for preparing the moisturizing and anti-aging microcapsule composition for cosmetics as described above comprises the following steps:
[0017] S1, mixing soybean lecithin, modified polylactic acid, Chondrus crispus and calcium alginate, heating and dissolving, adding Centella asiatica extract, Psoralea corylifolia extract, olive leaf extract, Scutellaria baicalensis extract and triethylhexanoin, dissolving evenly, to prepare a mixture;
[0018] S2, adding the mixture into a granulator for granulation, cooling down to form, and then cooling down to room temperature to prepare flexible beads;
[0019] S3, adding glycerol, butylene glycol, xanthan gum, gellan gum, 1,2-hexanediol, p-hydroxyacetophenone, trehalose, agar, hydroxyethyl cellulose, disodium EDTA, sodium hyaluronate and soluble collagen into water, heating and mixing evenly, and then cooling to room temperature to prepare a dispersion matrix;
[0020] S4, uniformly suspending the obtained flexible beads in a dispersion matrix to prepare the moisturizing and anti-aging microcapsule composition for cosmetics.
[0021] Preferably, the heating temperature in step S1 is 70-90°C.
[0022] Preferably, the heating temperature in step S3 is 45-60°C.
[0023] Beneficial effects of the present invention:
[0024] The invention uses chitosan and L-lactide to undergo graft copolymerization reaction in 1-butyl-3-methylimidazole chloride to prepare functionalized polylactic acid, and then grafts the functionalized polylactic acid with L-arginine to prepare modified polylactic acid, wherein chitosan has antibacterial and moisturizing effects, polylactic acid can stimulate collagen regeneration, effectively improve facial fine lines, wrinkles and skin sagging, and the main effects of L-arginine in skin care products include promoting collagen synthesis, moisturizing, anti-inflammatory and anti-oxidation, etc. The invention uses soybean lecithin, modified polylactic acid, Chondrus crispus and calcium alginate as microcapsule wall components, and active materials Centella asiatica extract, Psoralea corylifolia extract, Olive leaf extract, Scutellaria baicalensis extract and tri(ethylhexanoic acid)glycerol as microcapsule cores, wherein Chondrus crispus is a moisturizing substance extracted from natural seaweed, which can detoxify, deeply clean, remove aged cutin, tighten skin, moisturize, delay aging, and The invention has the effects of moisturizing, improving skin gloss and softness, and can form a protective film on the skin surface to effectively prevent water loss and help the skin maintain a moist state. Both Chondrus crispus and calcium alginate are used as film-forming substances. The present invention wraps the active material in the microcapsule wall to form a flexible bead pill, which has a good isolation and protection effect on the active material, and significantly improves the efficacy and stability of the active material. In addition, glycerol, butylene glycol, xanthan gum, gellan gum, 1,2-hexanediol, p-hydroxyacetophenone, trehalose, agar, hydroxyethyl cellulose, disodium EDTA, sodium hyaluronate, soluble collagen and water are used to prepare a dispersion matrix, and the flexible bead pills are evenly suspended in the dispersion matrix. The flexible bead pills prepared by the invention work synergistically with the dispersion matrix to give the cosmetics better anti-wrinkle and moisturizing effects, quickly tighten the skin, and smooth fine lines. DETAILED DESCRIPTION
[0025] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0026] Embodiment 1 A method for preparing modified polylactic acid comprises the following steps:
[0027] (1) 15 mL of 1-butyl-3-methylimidazole chloride was placed in a reactor, stirred at 80 ° C, 1 g of chitosan was added, and stirred for 3 h under a nitrogen atmosphere. Then 4 g of L-lactide and 0.02 g of stannous octoate were added to react for 12 h. After the reaction was completed, isopropanol was added to terminate the reaction, and stirring was continued for 10 h. Then, the functionalized polylactic acid was prepared by filtering, washing, and drying.
[0028] (2) 1.2 g of L-arginine, 1 g of 1-ethyl-(3-dimethylaminopropyl)carbodiimide and 0.7 g of N-hydroxysuccinimide were dissolved in 100 mL of deionized water, and the mixture was stirred in an ice water bath for 2 h to activate the carboxyl groups, thereby preparing an activated arginine solution;
[0029] (3) 1 g of functionalized polylactic acid was added to the activated arginine solution and mixed, and the mixture was reacted at 40° C. for 24 h. After the reaction was completed, the mixture was filtered and dried to obtain modified polylactic acid.
[0030] Example 2 A moisturizing and anti-aging microcapsule composition for cosmetics, comprising a dispersion matrix and flexible beads uniformly suspended in the dispersion matrix;
[0031] According to the weight percentage in the microcapsule composition, the flexible beads include: 0.003% of Centella asiatica extract, 0.003% of White Wild Vinegar extract, 0.002% of Olive Leaf Extract, 0.002% of Scutellaria Baicalensis Extract, 17% of triethylhexanoin, 2% of soy lecithin, 2% of modified polylactic acid prepared in Example 1, 0.2% of Chondrus crispus, and 2% of calcium alginate; the dispersed matrix includes: 11% of glycerol, 2% of butylene glycol, 0.5% of xanthan gum, 0.07% of gellan gum, 0.6% of 1,2-hexanediol, 0.25% of p-hydroxyacetophenone, 0.15% of trehalose, 0.34% of agar, 0.1% of hydroxyethyl cellulose, 0.01% of disodium EDTA, 0.02% of sodium hyaluronate, 0.005% of soluble collagen, and 55% of water.
[0032] The preparation method of the above-mentioned moisturizing and anti-aging microcapsule composition for cosmetics comprises the following steps:
[0033] S1, mixing soybean lecithin, modified polylactic acid, Chondrus crispus and calcium alginate, heating to 80°C to dissolve, adding Centella asiatica extract, Psoralea corylifolia extract, Olive leaf extract, Scutellaria baicalensis extract and triethylhexanoin, dissolving evenly to prepare a mixture;
[0034] S2, adding the mixture into a granulator for granulation, cooling down to form, and then cooling down to room temperature to prepare flexible beads;
[0035] S3, adding glycerol, butylene glycol, xanthan gum, gellan gum, 1,2-hexanediol, p-hydroxyacetophenone, trehalose, agar, hydroxyethyl cellulose, disodium EDTA, sodium hyaluronate and soluble collagen into water, heating to 60° C. and mixing evenly, then cooling to room temperature to prepare a dispersion matrix;
[0036] S4. The obtained flexible beads are uniformly suspended in a dispersion matrix to prepare a moisturizing and anti-aging microcapsule composition for cosmetics.
[0037] Example 3 A moisturizing and anti-aging microcapsule composition for cosmetics, comprising a dispersion matrix and flexible beads uniformly suspended in the dispersion matrix;
[0038] According to the weight percentage in the microcapsule composition, the flexible beads include: 0.004% Centella asiatica extract, 0.004% White Wild Vine extract, 0.003% Olive leaf extract, 0.003% Scutellaria baicalensis extract, 18% triethylhexanoin, 2% soy lecithin, 3% modified polylactic acid prepared in Example 1, 0.5% Chondrus crispus, and 1% calcium alginate; the dispersed matrix includes: 25% glycerol, 3% butylene glycol, 0.7% xanthan gum, 0.14% gellan gum, 0.8% 1,2-hexanediol, 0.4% p-hydroxyacetophenone, 0.5% trehalose, 0.6% agar, 0.3% hydroxyethyl cellulose, 0.03% disodium EDTA, 0.04% sodium hyaluronate, 0.003% soluble collagen, and 60% water.
[0039] The preparation method of the above-mentioned moisturizing and anti-aging microcapsule composition for cosmetics is the same as that of Example 2.
[0040] Example 4 A moisturizing and anti-aging microcapsule composition for cosmetics, comprising a dispersion matrix and flexible beads uniformly suspended in the dispersion matrix;
[0041] According to the weight percentage in the microcapsule composition, the flexible beads include: 0.005% of Centella asiatica extract, 0.005% of White Wild Vinegar extract, 0.004% of Olive leaf extract, 0.004% of Scutellaria baicalensis extract, 20% of triethylhexanoin, 5% of soy lecithin, 4% of modified polylactic acid prepared in Example 1, 1% of Chondrus crispus, and 0.7% of calcium alginate; the dispersed matrix includes: 37% of glycerol, 5% of butylene glycol, 1% of xanthan gum, 0.2% of gellan gum, 1% of 1,2-hexanediol, 0.8% of p-hydroxyacetophenone, 0.7% of trehalose, 0.8% of agar, 0.5% of hydroxyethyl cellulose, 0.05% of disodium EDTA, 0.05% of sodium hyaluronate, 0.01% of soluble collagen, and 65% of water.
[0042] The preparation method of the above-mentioned moisturizing and anti-aging microcapsule composition for cosmetics is the same as that of Example 2.
[0043] Comparative Example 1 A moisturizing and anti-aging microcapsule composition for cosmetics, comprising a dispersion matrix and flexible beads uniformly suspended in the dispersion matrix;
[0044] According to the weight percentage in the microcapsule composition, the flexible beads include: 0.003% of Centella asiatica extract, 0.003% of Orchidaceae extract, 0.002% of Olive leaf extract, 0.002% of Scutellaria baicalensis extract, 17% of triethylhexanoin, 2% of soybean lecithin, 2% of modified polylactic acid prepared in Example 1, and 2.2% of calcium alginate; the dispersed matrix includes: 11% of glycerol, 2% of butylene glycol, 0.5% of xanthan gum, 0.07% of gellan gum, 0.6% of 1,2-hexanediol, 0.25% of p-hydroxyacetophenone, 0.15% of trehalose, 0.34% of agar, 0.1% of hydroxyethyl cellulose, 0.01% of disodium EDTA, 0.02% of sodium hyaluronate, 0.005% of soluble collagen, and 55% of water.
[0045] The preparation method of the above-mentioned moisturizing and anti-aging microcapsule composition for cosmetics is the same as that of Example 2.
[0046] Comparative Example 2 A moisturizing and anti-aging microcapsule composition for cosmetics, comprising a dispersion matrix and flexible beads uniformly suspended in the dispersion matrix;
[0047] According to the weight percentage in the microcapsule composition, the flexible beads include: 0.003% of Centella asiatica extract, 0.003% of White Wild Vinegar extract, 0.002% of Olive leaf extract, 0.002% of Scutellaria baicalensis extract, 17% of triethylhexanoin, 2% of soy lecithin, 2% of modified polylactic acid prepared in Example 1, and 2.2% of Chondrus crispus; the dispersed matrix includes: 11% of glycerol, 2% of butylene glycol, 0.5% of xanthan gum, 0.07% of gellan gum, 0.6% of 1,2-hexanediol, 0.25% of p-hydroxyacetophenone, 0.15% of trehalose, 0.34% of agar, 0.1% of hydroxyethyl cellulose, 0.01% of disodium EDTA, 0.02% of sodium hyaluronate, 0.005% of soluble collagen, and 55% of water.
[0048] The preparation method of the above-mentioned moisturizing and anti-aging microcapsule composition for cosmetics is the same as that of Example 2.
[0049] Comparative Example 3: A moisturizing and anti-aging microcapsule composition for cosmetics, comprising a dispersion matrix and flexible beads uniformly suspended in the dispersion matrix;
[0050] According to the weight percentage in the microcapsule composition, the flexible beads include: 0.003% Centella asiatica extract, 0.003% White Wild Vine extract, 0.002% Olive leaf extract, 0.002% Scutellaria baicalensis extract, 17% triethylhexanoin, 2% soy lecithin, 2% polylactic acid, 0.2% Chondrus crispus, and 2% calcium alginate; the dispersed matrix includes: 11% glycerol, 2% butylene glycol, 0.5% xanthan gum, 0.07% gellan gum, 0.6% 1,2-hexanediol, 0.25% p-hydroxyacetophenone, 0.15% trehalose, 0.34% agar, 0.1% hydroxyethyl cellulose, 0.01% disodium EDTA, 0.02% sodium hyaluronate, 0.005% soluble collagen, and 55% water.
[0051] The preparation method of the above-mentioned moisturizing and anti-aging microcapsule composition for cosmetics is the same as that of Example 2.
[0052] Comparative Example 4: A moisturizing and anti-aging microcapsule composition for cosmetics, comprising a dispersion matrix and flexible beads uniformly suspended in the dispersion matrix;
[0053] According to the weight percentage in the microcapsule composition, the flexible beads include: 0.003% of Centella asiatica extract, 0.003% of White Wild Vinegar extract, 0.002% of Olive leaf extract, 0.002% of Scutellaria baicalensis extract, 17% of triethylhexanoin, 2% of soy lecithin, 2% of modified polylactic acid prepared in Example 1, 0.2% of Chondrus crispus, and 2% of calcium alginate; the dispersed matrix includes: 11% of glycerol, 2% of butylene glycol, 0.5% of xanthan gum, 0.07% of gellan gum, 0.6% of 1,2-hexanediol, 0.25% of p-hydroxyacetophenone, 0.15% of trehalose, 0.34% of agar, 0.1% of hydroxyethyl cellulose, 0.01% of disodium EDTA, 0.02% of sodium hyaluronate, and 55% of water.
[0054] The preparation method of the above-mentioned moisturizing and anti-aging microcapsule composition for cosmetics is the same as that of Example 2.
[0055] Performance Testing
[0056] The microcapsule compositions prepared in Examples 2-4 and Comparative Examples 1-4 were subjected to performance testing:
[0057] (1) Antioxidant capacity and anti-wrinkle test: The antioxidant capacity test used the ORAC analysis method. ORAC is the abbreviation of oxidative free radical absorbance capacity, which is also called antioxidant capacity. It is based on the principle that free radicals destroy fluorescent probes and cause changes in fluorescence intensity. Trolox, a water-soluble analog of vitamin E, was used as the quantitative standard and analyzed using a fluorescent microplate analyzer. The anti-wrinkle test used the VISIA-CR facial skin image analyzer to measure the wrinkle reduction rate after 28 days. The data results are shown in Table 1.
[0058] Table 1 Antioxidant capacity and anti-wrinkle test results of samples
[0059]
[0060] It can be seen from the data in Table 1 that the microcapsule compositions prepared in Examples 2-4 of the present invention have good antioxidant capacity and anti-wrinkle performance, wherein no crispa component was added in Comparative Example 1, no calcium alginate component was added in Comparative Example 2, the polylactic acid was not modified in Comparative Example 3, and no soluble collagen component was added in Comparative Example 4. It was measured that the average antioxidant capacity and wrinkle reduction rate of Comparative Examples 1, 3, and 4 were worse than those of Examples 2-4, indicating that the present invention has excellent anti-aging effect through the synergistic effect of crispa, modified polylactic acid and soluble collagen components.
[0061] (2) Moisturizing performance test: Skin aging is closely related to the moisture content of the skin. Skin dehydration can accelerate skin aging, while sufficient skin moisture content can make the skin soft and elastic and delay aging. The Corneometer-capacitance method was used to test the changes in skin moisture content of 30 volunteers to evaluate the moisturizing performance of the test samples.
[0062] The 30 subjects were healthy female volunteers aged 20 to 40 years old with no history of skin diseases. Before the test, the volunteers were required to enter a constant temperature and humidity test environment (temperature of 20±1°C, relative humidity of 40-60%) and rest for 30 minutes. Several points of the same area were defined on the left forearm as the use areas of Examples 1-3 and the control group, and the points at the same position on the right forearm were used as the use areas of Comparative Examples 1-4. The corresponding areas of the left and right forearms were tested simultaneously, and the dosage of each point was 5 mg / cm 2 The changes in skin moisture content after 20 minutes, 2 hours, 10 hours, and 24 hours of application were observed to indicate the moisturizing performance of the sample to be tested. Moisturizing rate = (AB) / B×100%, where A indicates the moisture content of the skin after adding the test sample, and B indicates the moisture content of the skin without adding the test sample. The data results are shown in Table 2.
[0063] Table 2 Test results of sample moisturizing performance
[0064]
[0065] It can be seen from the data in Table 2 that the microcapsule composition prepared in Examples 2-4 of the present invention still maintains a good moisturizing effect after 24 hours, can quickly replenish moisture to the skin in a short period of time, and has a good water-locking function, which can achieve long-term moisturizing of the skin throughout the day.
[0066] In the description of this specification, the description with reference to the terms "one embodiment", "example", "specific example", etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic representation of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner.
[0067] The above shows and describes the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited to the above embodiments, and the above embodiments and descriptions are only for explaining the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, and these changes and improvements all fall within the scope of the present invention to be protected.
Claims
1. A moisturizing and anti-aging microcapsule composition for cosmetics, characterized in that: The invention comprises a dispersed matrix and flexible beads uniformly suspended in the dispersed matrix, wherein the flexible beads comprise active materials and microcapsule walls, wherein the active materials comprise Centella asiatica extract, Viburnum oleifera extract, olive leaf extract, Scutellaria baicalensis extract and triethylhexanoin, and the microcapsule walls comprise soybean lecithin, modified polylactic acid, Chondrus crispus and calcium alginate, wherein the active materials are wrapped in the microcapsule walls, and the modified polylactic acid is prepared by grafting and copolymerizing chitosan and L-lactide in 1-butyl-3-methylimidazole chloride and then grafting and modifying with L-arginine.
2. The moisturizing and anti-aging microcapsule composition for cosmetics according to claim 1, characterized in that: According to the weight percentage of the microcapsule composition, the flexible beads include: 0.003-0.005% of Centella asiatica extract, 0.003-0.005% of Orchidaceae extract, 0.002-0.004% of Olive leaf extract, 0.002-0.004% of Scutellaria baicalensis extract, 15-20% of triethylhexanoin, 2-5% of soy lecithin, 2-4% of modified polylactic acid, 0.1-1% of Chondrus crispus, and 0.5-2% of calcium alginate.
3. The moisturizing and anti-aging microcapsule composition for cosmetics according to claim 1, characterized in that: According to the weight percentage in the microcapsule composition, the dispersed matrix includes: 10-40% glycerol, 2-5% butylene glycol, 0.3-1% xanthan gum, 0.05-0.2% gellan gum, 0.5-1% 1,2-hexanediol, 0.23-0.8% p-hydroxyacetophenone, 0.1-1% trehalose, 0.3-0.8% agar, 0.1-0.5% hydroxyethyl cellulose, 0.01-0.05% disodium EDTA, 0.01-0.05% sodium hyaluronate, 0.003-0.01% soluble collagen, and 55-65% water.
4. The moisturizing and anti-aging microcapsule composition for cosmetics according to claim 1, characterized in that: The preparation method of the modified polylactic acid comprises the following steps: (1) 1-butyl-3-methylimidazole chloride is placed in a reactor, stirred at 75-85° C., chitosan is added, and stirred for 3-4 hours under a nitrogen atmosphere, and then L-lactide and stannous octoate are added to react for 10-12 hours. After the reaction is completed, isopropanol is added to terminate the reaction, and stirring is continued for 8-12 hours, and then filtered, washed, and dried to prepare functionalized polylactic acid; (2) dissolving L-arginine, 1-ethyl-(3-dimethylaminopropyl)carbodiimide and N-hydroxysuccinimide in deionized water, placing in an ice water bath and stirring for 1 to 3 hours to activate the carboxyl groups, thereby preparing an activated arginine solution; (3) Adding the functionalized polylactic acid to the activated arginine solution, mixing the mixture, and reacting the mixture at 30 to 50° C. for 20 to 24 hours. After the reaction is completed, filtering and drying are performed to obtain the modified polylactic acid.
5. The moisturizing and anti-aging microcapsule composition for cosmetics according to claim 4, characterized in that: In the step (1), the addition ratio of 1-butyl-3-methylimidazole chloride, chitosan and L-lactide is 10-20 mL: 1 g: 4-6 g.
6. The moisturizing and anti-aging microcapsule composition for cosmetics according to claim 1, characterized in that: The particle size of the flexible beads is 1 to 8 mm.
7. The moisturizing and anti-aging microcapsule composition for cosmetics according to claim 1, characterized in that: The ratio of the diameter of the active material to the ring width of the microcapsule wall is 1:1-3.
8. A method for preparing a moisturizing and anti-aging microcapsule composition for cosmetics according to any one of claims 1 to 7, characterized in that: The following steps are involved: S1, mixing soybean lecithin, modified polylactic acid, Chondrus crispus and calcium alginate, heating and dissolving, adding Centella asiatica extract, Psoralea corylifolia extract, olive leaf extract, Scutellaria baicalensis extract and triethylhexanoin, dissolving evenly, to prepare a mixture; S2, adding the mixture into a granulator for granulation, cooling down to form, and then cooling down to room temperature to prepare flexible beads; S3, adding glycerol, butylene glycol, xanthan gum, gellan gum, 1,2-hexanediol, p-hydroxyacetophenone, trehalose, agar, hydroxyethyl cellulose, disodium EDTA, sodium hyaluronate and soluble collagen into water, heating and mixing evenly, and then cooling to room temperature to prepare a dispersion matrix; S4, uniformly suspending the obtained flexible beads in a dispersion matrix to prepare the moisturizing and anti-aging microcapsule composition for cosmetics.
9. The method for preparing the moisturizing and anti-aging microcapsule composition for cosmetics according to claim 8, characterized in that: The heating temperature in step S1 is 70-90°C.
10. The method for preparing the moisturizing and anti-aging microcapsule composition for cosmetics according to claim 8, characterized in that: The heating temperature in step S3 is 45-60°C.
Citation Information
Patent Citations
Microcapsule wrapping active matter and preparation method thereof
CN115177536A
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CN115671022A
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