Preparation method of dressing capable of promoting blood circulation to remove blood stasis and dressing

Abstract

A preparation method of a dressing capable of promoting blood circulation to remove blood stasis comprises the following steps that firstly, EVAL powder is evenly scattered on PP spunbond cloth, then the face, where the EVAL powder is scattered, of the PP spunbond cloth is laminated and compounded with a PE spunbond film, and an SF film composite material is obtained; the preparation method comprises the following steps: preparing an SF film composite material into an open cloth bag, filling a proper amount of iron powder and carbon powder into the cloth bag, sealing to obtain a chemical hot compress bag, compounding the chemical hot compress bag into a pure cotton spunlace non-woven fabric, and compounding a layer of flash non-woven fabric on the top of the pure cotton spunlace non-woven fabric to obtain a heating non-woven fabric; the preparation method comprises the following steps: respectively preparing a pva solution and a carboxymethyl chitosan solution, uniformly mixing a proper amount of the pva solution and the carboxymethyl chitosan solution, adding a proper amount of a magnesium sulfate solution, uniformly stirring, standing, and carrying out condensation molding to obtain skin-friendly hydrogel; and adhering the skin-friendly hydrogel to the bottom of the heating non-woven fabric to obtain the dressing for promoting blood circulation to remove blood stasis. According to the invention, stable temperature can be maintained.

Description

Technical Field

[0001] The invention relates to an improvement in the preparation of a blood-activating and stasis-removing dressing, belongs to the medical field, and particularly relates to a preparation method of a blood-activating and stasis-removing dressing and the dressing. Background Art

[0002] Phlebitis refers to an acute aseptic inflammation of the veins. Depending on the location of the lesion, phlebitis can be divided into superficial phlebitis and deep phlebitis. Its pathological changes include vascular intimal hyperplasia, narrowing of the vascular lumen, and slowed blood flow. Patients often have symptoms of pain and inflammation. Hot compresses at an appropriate temperature can promote vascular dilation and congestion, accelerate the body's metabolism, effectively relieve symptoms, and promote the dissipation of inflammation. Therefore, hot compresses are used to treat phlebitis in the existing technology.

[0003] The most common hot compress method in the prior art is: take a certain amount of magnesium sulfate and add it into warm water to dissolve it to obtain a magnesium sulfate solution, then immerse medical gauze in the magnesium sulfate solution, and then take out the magnesium sulfate gauze carrying a certain amount of heat. Then the relevant personnel use the magnesium sulfate gauze to perform hot compress on the patient. The magnesium sulfate gauze obtained by this method has a short heat preservation time, heat dissipation is fast, and the heating temperature cannot be maintained in a stable state, resulting in poor effect in relieving inflammation.

[0004] The Chinese patent application with application number CN202410242637.5 and application date March 4, 2024 discloses a biomedical hydrogel composite material and a preparation method thereof, the formula of which includes: polyvinyl alcohol hydrogel, graphene composite hydrogel, phase change hydrogel and traditional Chinese medicine liquid composite hydrogel, and the weight proportions of each component are: 3-30 parts of polyvinyl alcohol hydrogel, 1-10 parts of graphene composite hydrogel, 10-50 parts of phase change hydrogel and 5-30 parts of traditional Chinese medicine liquid. Composite hydrogel; preparation method, comprising the following steps: step one, preparing materials; step two, coating; step three, cutting; step four, storing; by coating polyvinyl alcohol-based hydrogel, graphene composite hydrogel, phase change hydrogel and traditional Chinese medicine liquid composite hydrogel on non-woven fabric, it becomes a medical polymer bandage that can be used for cold or hot compress, and the quality of the bandage is improved, but the above technology only records that biomedical hydrogel can be used for hot compress, and there is no relevant record of how to maintain a stable temperature.

[0005] The information disclosed in this background technology section is only intended to increase the understanding of the overall background of this patent application, and should not be regarded as acknowledging or suggesting in any form that the information constitutes the prior art already known to ordinary technicians in this field. Summary of the invention

[0006] The purpose of the present invention is to overcome the problem in the prior art that it is difficult to maintain a stable temperature, and to provide a preparation method and a dressing for promoting blood circulation and removing blood stasis that can maintain a stable temperature.

[0007] To achieve the above objectives, the technical solution of the present invention is: a method for preparing a blood-activating and blood-stasis-removing dressing, the method for preparing the blood-activating and blood-stasis-removing dressing comprising the following steps:

[0008] The first step is to evenly sprinkle EVAL powder on the PP spunbond fabric, and then laminate the side of the PP spunbond fabric sprinkled with EVAL powder with the PE spunbond film to obtain a SF film composite material;

[0009] The second step is to make the SF membrane composite material into an open cloth bag, then fill the cloth bag with an appropriate amount of iron powder and carbon powder and seal it to obtain a chemical hot compress bag, then compound the chemical hot compress bag into the pure cotton spunlace nonwoven fabric, and then compound a layer of flash nonwoven fabric on the top of the pure cotton spunlace nonwoven fabric;

[0010] Step 3: First, prepare a PVA solution and a carboxymethyl chitosan solution respectively, then take an appropriate amount of the PVA solution and the carboxymethyl chitosan solution and mix them evenly, then add an appropriate amount of magnesium sulfate solution and stir evenly, and condense and form after standing to obtain a skin-friendly hydrogel;

[0011] Step 4: The skin-friendly hydrogel is adhered to the bottom of the pure cotton spunlace nonwoven fabric to obtain a blood-activating and blood-stasis-removing dressing.

[0012] In the first step, EVAL powder is first evenly sprinkled on the PP spunbond fabric, and then the side of the PP spunbond fabric sprinkled with EVAL powder is laminated with the PE spunbond film to obtain the SF membrane composite material. Specifically, the prepared PP spunbond fabric is first evenly sprinkled with EVAL powder, and then the powder is melted by heating and introduced into the PE breathable film, and the hot melt adhesive is infiltrated into the surface of the two layers of materials, and then a laminating machine is used to pressurize the hot melt adhesive to solidify it in a short time, so that the PP spunbond fabric and the PE breathable film are bonded together to form a SF membrane composite material.

[0013] In the second step, the appropriate amount of iron powder and carbon powder is specifically: the mass percentage of iron powder to carbon powder is 5-20: carbon powder is 1-10.

[0014] In the second step, the chemical hot compress pack is compounded in the pure cotton spunlace nonwoven fabric, specifically: the upper layer is pure cotton spunlace nonwoven fabric, the middle chemical hot compress pack, and the lower layer is pure cotton spunlace nonwoven fabric, and the upper and lower layers of pure cotton spunlace nonwoven fabric wrap the chemical hot compress therein.

[0015] The chemical hot compress pack has a heating rate of 8°C / min-14°C / min, a temperature of 31°C-65°C, and a continuous heating time of 140 minutes-201 minutes.

[0016] The pure cotton spunlace nonwoven fabric has the same length and width as the flash-spun nonwoven fabric, and the length and width of the pure cotton spunlace nonwoven fabric are greater than the length and width of the skin-friendly hydrogel.

[0017] The pure cotton spunlace nonwoven fabric and the flash-steamed nonwoven fabric are both in the shape of a 15 cm×15 cm square, and the magnesium sulfate skin-friendly hydrogel is in the shape of a 5×5 cm square.

[0018] In the third step, the mass fraction ratio of the PVA solution is 5%-20%, the mass fraction ratio of the carboxymethyl chitosan solution is 5%-20%, and the mass fraction ratio of the magnesium sulfate solution is 10%-40%;

[0019] The volume ratio of the PVA solution, the carboxymethyl chitosan solution and the magnesium sulfate solution is 2-15:2-15:0.1-1.

[0020] The preparation method of the PVA solution is as follows: 5-15g of polyvinyl alcohol is placed in 40g of deionized water, and heated and ultrasonically treated for 5 minutes to obtain a PVA solution;

[0021] The preparation method of the carboxymethyl chitosan solution is as follows: then taking 5-15g of carboxymethyl chitosan and placing it in 40g of deionized water to obtain a carboxymethyl chitosan solution;

[0022] The preparation method of the magnesium sulfate solution is as follows: 10-50 g of magnesium sulfate is dissolved in 40° C. warm water to obtain a magnesium sulfate solution;

[0023] The step of condensing and forming after standing to obtain the skin-friendly hydrogel is specifically as follows: the magnesium sulfate solution is ultrasonically treated for 5 minutes, poured into a mold, and then condensed for 12 hours to obtain the skin-friendly hydrogel.

[0024] A blood-activating and stasis-removing dressing is prepared by the above-mentioned preparation method of a blood-activating and stasis-removing dressing, and the blood-activating and stasis-removing dressing comprises a flash-steamed nonwoven fabric, a pure cotton spunlace nonwoven fabric, a hot compress pack and a skin-friendly hydrogel, wherein the flash-steamed nonwoven fabric is arranged on the top of the pure cotton spunlace nonwoven fabric, the hot compress pack is embedded in the pure cotton spunlace nonwoven fabric, and the skin-friendly hydrogel is arranged on the bottom of the pure cotton spunlace nonwoven fabric.

[0025] Compared with the prior art, the present invention has the following beneficial effects:

[0026] 1. In the preparation method and dressing of a blood-activating and stasis-removing dressing of the present invention, the skin-friendly hydrogel in the dressing is firstly attached to the wound, and then the whole dressing is fixed. Since the pure cotton spunlace nonwoven fabric is used as the material for wrapping the hot compress bag, after water-repellent finishing, the average effective pore size inside the pure cotton spunlace nonwoven fabric is increased, a continuous water-repellent film is formed on the surface of the cotton fiber, and the fiber parts are bonded and held more tightly, resulting in the formation of larger holes inside. At this time, the exudate of the wound is stored by the pure cotton spunlace nonwoven fabric, and the chemical hot compress bag is wrapped by the pure cotton spunlace nonwoven fabric. When the exudate drips into the hot compress bag, heat is generated and heat is started to be generated. In addition, the magnesium sulfate skin-friendly hydrogel on the pure cotton spunlace nonwoven fabric will directly adhere to the skin, and the hydrogel contains a large amount of skin-friendly substances, which makes it close to the skin. Patients are not prone to tingling when in contact, magnesium ions enter the human body to react, can inhibit platelet function and regulate coagulation state, stimulate Na+, K+, ATP enzymes at low concentrations, and inhibit their activity at high concentrations, regulate transmembrane sodium and potassium movement, thereby downregulating inflammatory mediators, reducing inflammatory reactions, and curing congestion. In addition, the chemical hot compress pack will continue to heat according to the exudation of the exudate, and due to the good thermal insulation effect of the pure cotton spunlace nonwoven fabric, the thermal insulation effect of the hot compress pack is improved, and the use of carbon powder in the chemical hot compress pack can speed up the heating efficiency of the iron powder, and at this temperature, the magnesium sulfate in the skin-friendly hydrogel can be better penetrated into the wound, reducing the inflammatory reaction around the wound, and more conducive to the patient's recovery. The magnesium sulfate skin-friendly hydrogel can be directly attached to the wound for use. Therefore, the present invention can maintain a stable temperature.

[0027] 2. In the preparation method and dressing of the blood-activating and stasis-removing dressing of the present invention, the pure cotton spunlace nonwoven fabric becomes hard after water-repellent finishing, and has high air permeability, high rigidity and flexibility, and excellent skin-friendly performance; at the same time, the flash-steamed nonwoven fabric has good water-repellent effect, which can prevent the test liquid from contacting the skin, so that the pure cotton spunlace fabric can quickly absorb the liquid and allow the liquid to diffuse inside it, and has a long-term water storage capacity, so that the hot compress pack can release heat stably for a long time. Therefore, the hot compress pack of the present invention can release heat stably for a long time and has a good waterproof effect.

[0028] 3. In the preparation method and dressing of the blood-activating and stasis-removing dressing of the present invention, the hydrogel can absorb and fix water several times or even hundreds of times its weight to form a soft and moist gel-like substance. The hydrogel can retain water and has a certain air permeability, which helps to maintain the normal breathing of the skin or tissue. The total area reduction rate and volume reduction rate of the wound surface using the hydrogel dressing are higher than those of the traditional bandage treatment, and the effect is better. Therefore, the present invention has good air permeability and good use effect.

[0029] 4. In the preparation method and dressing of the blood-activating and stasis-removing dressing of the present invention, the diameter of the flash-spun nonwoven fabric spun on the outermost layer of the dressing is as fine as 0.11 dtex, with high crystallinity and good fiber orientation, so that it has high strength and good tear resistance, which is 2-3 times that of polypropylene nonwoven fabrics produced by other methods, is not easy to lint, does not absorb dust, has good dimensional stability, good waterproof and breathable properties, and has strength several times that of other spunbond products at the same surface density. Therefore, the present invention has high lightness and good waterproof and breathable properties. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figure 1 It is a structural schematic diagram of the present invention.

[0031] Figure 2 It is a schematic diagram of the temperature change curve of the heating pack in the present invention.

[0032] Figure 3 It is a graph of the heating rate of the heating pack in the present invention. DETAILED DESCRIPTION

[0033] The present invention is further described in detail below in conjunction with the accompanying drawings and specific implementation methods.

[0034] See also Figures 1 to 3 , a method for preparing a blood-activating and stasis-removing dressing, the method for preparing the blood-activating and stasis-removing dressing comprising the following steps:

[0035] The first step is to evenly sprinkle EVAL powder on the PP spunbond fabric, and then laminate the side of the PP spunbond fabric sprinkled with EVAL powder with the PE spunbond film to obtain a SF film composite material;

[0036] The second step is to make the SF membrane composite material into an open cloth bag, then fill the cloth bag with an appropriate amount of iron powder and carbon powder and seal it to obtain a chemical hot compress bag, then compound the chemical hot compress bag into the pure cotton spunlace nonwoven fabric, and then compound a layer of flash nonwoven fabric on the top of the pure cotton spunlace nonwoven fabric;

[0037] Step 3: First, prepare a PVA solution and a carboxymethyl chitosan solution respectively, then take an appropriate amount of the PVA solution and the carboxymethyl chitosan solution and mix them evenly, then add an appropriate amount of magnesium sulfate solution and stir evenly, and condense and form after standing to obtain a skin-friendly hydrogel;

[0038] Step 4: The skin-friendly hydrogel is adhered to the bottom of the pure cotton spunlace nonwoven fabric to obtain a blood-activating and blood-stasis-removing dressing.

[0039] In the first step, EVAL powder is first evenly sprinkled on the PP spunbond fabric, and then the side of the PP spunbond fabric sprinkled with EVAL powder is laminated with the PE spunbond film to obtain the SF membrane composite material. Specifically, the prepared PP spunbond fabric is first evenly sprinkled with EVAL powder, and then the powder is melted by heating and introduced into the PE breathable film, and the hot melt adhesive is infiltrated into the surface of the two layers of materials, and then a laminating machine is used to pressurize the hot melt adhesive to solidify it in a short time, so that the PP spunbond fabric and the PE breathable film are bonded together to form a SF membrane composite material.

[0040] In the second step, the appropriate amount of iron powder and carbon powder is specifically: the mass percentage of iron powder to carbon powder is 5-20: carbon powder is 1-10.

[0041] In the second step, the chemical hot compress pack is compounded in the pure cotton spunlace nonwoven fabric, specifically: the upper layer is pure cotton spunlace nonwoven fabric, the middle chemical hot compress pack, and the lower layer is pure cotton spunlace nonwoven fabric, and the upper and lower layers of pure cotton spunlace nonwoven fabric wrap the chemical hot compress therein.

[0042] The chemical hot compress pack has a heating rate of 8°C / min-14°C / min, a temperature of 31°C-65°C, and a continuous heating time of 140 minutes-201 minutes.

[0043] The pure cotton spunlace nonwoven fabric has the same length and width as the flash-spun nonwoven fabric, and the length and width of the pure cotton spunlace nonwoven fabric are greater than the length and width of the skin-friendly hydrogel.

[0044] The pure cotton spunlace nonwoven fabric and the flash-steamed nonwoven fabric are both in the shape of a 15 cm×15 cm square, and the magnesium sulfate skin-friendly hydrogel is in the shape of a 5×5 cm square.

[0045] In the third step, the mass fraction ratio of the PVA solution is 5%-20%, the mass fraction ratio of the carboxymethyl chitosan solution is 5%-20%, and the mass fraction ratio of the magnesium sulfate solution is 10%-40%;

[0046] The volume ratio of the PVA solution, the carboxymethyl chitosan solution and the magnesium sulfate solution is 2-15:2-15:0.1-1.

[0047] The preparation method of the PVA solution is as follows: 5-15g of polyvinyl alcohol is placed in 40g of deionized water, and heated and ultrasonically treated for 5 minutes to obtain a PVA solution;

[0048] The preparation method of the carboxymethyl chitosan solution is as follows: then taking 5-15g of carboxymethyl chitosan and placing it in 40g of deionized water to obtain a carboxymethyl chitosan solution;

[0049] The preparation method of the magnesium sulfate solution is as follows: 10-50 g of magnesium sulfate is dissolved in 40° C. warm water to obtain a magnesium sulfate solution;

[0050] The step of condensing and forming after standing to obtain the skin-friendly hydrogel is specifically as follows: the magnesium sulfate solution is ultrasonically treated for 5 minutes, poured into a mold, and then condensed for 12 hours to obtain the skin-friendly hydrogel.

[0051] A blood-activating and stasis-removing dressing is prepared by the above-mentioned preparation method of a blood-activating and stasis-removing dressing, and the blood-activating and stasis-removing dressing comprises a flash-steamed nonwoven fabric, a pure cotton spunlace nonwoven fabric, a hot compress pack and a skin-friendly hydrogel, wherein the flash-steamed nonwoven fabric is arranged on the top of the pure cotton spunlace nonwoven fabric, the hot compress pack is embedded in the pure cotton spunlace nonwoven fabric, and the skin-friendly hydrogel is arranged on the bottom of the pure cotton spunlace nonwoven fabric.

[0052] A blood-activating and stasis-removing dressing, which is prepared by the preparation method of the blood-activating and stasis-removing dressing, and comprises a flash-steamed nonwoven fabric, a pure cotton spunlace nonwoven fabric, a hot compress pack and a skin-friendly hydrogel, wherein the flash-steamed nonwoven fabric is arranged on the top of the pure cotton spunlace nonwoven fabric, the hot compress pack is embedded in the pure cotton spunlace nonwoven fabric, and the skin-friendly hydrogel is arranged on the bottom of the pure cotton spunlace nonwoven fabric.

[0053] The supplementary description of the present invention is as follows:

[0054] The dressing size can also be 20cm×20cm, 20cm×30cm, and 15cm×20cm, and is used for partial-thickness and full-thickness skin injuries with fluid penetration.

[0055] Embodiment 1:

[0056] A method for preparing a blood-activating and stasis-removing dressing, comprising the following steps:

[0057] The first step is to evenly sprinkle EVAL powder on the PP spunbond fabric, and then laminate the side of the PP spunbond fabric sprinkled with EVAL powder with the PE spunbond film to obtain a SF membrane composite material, where the SF membrane is a waterproof and oil-proof membrane;

[0058] The second step is to make the SF membrane composite material into an open cloth bag, and then fill 5-20g of iron powder and 1-10g of carbon powder into the cloth bag to obtain a chemical hot compress bag, and then seal the chemical hot compress bag and compound it with the pure cotton spunlace nonwoven fabric, and then compound a layer of flash nonwoven fabric on the top of the pure cotton spunlace nonwoven fabric;

[0059] Step 3: first take 5-15g of polyvinyl alcohol and place it in 40g of deionized water, heat and ultrasonically treat it for 5min to obtain a PVA solution for use, then take 5-15g of carboxymethyl chitosan and place it in 40g of deionized water to obtain a carboxymethyl chitosan solution for use, then take 10-50g of magnesium sulfate and place it in 40°C warm water to dissolve to obtain a magnesium sulfate solution, then take 2-15ml of the PVA solution and the carboxymethyl chitosan solution respectively, mix and stir evenly, then add 0.1-1ml of magnesium sulfate solution and ultrasonically treat it for 5min, then pour it into a mold, and then condense it for 12h to form it, to obtain a skin-friendly hydrogel;

[0060] Step 4: The skin-friendly hydrogel is adhered to the bottom of the pure cotton spunlace nonwoven fabric to obtain a blood-activating and blood-stasis-removing dressing.

[0061] A blood-activating and stasis-removing dressing is prepared by the preparation method of the blood-activating and stasis-removing dressing, and comprises a flash-steamed nonwoven fabric, a pure cotton spunlace nonwoven fabric, a hot compress pack and a skin-friendly hydrogel, wherein the flash-steamed nonwoven fabric is arranged on the top of the pure cotton spunlace nonwoven fabric, the hot compress pack is embedded in the pure cotton spunlace nonwoven fabric, and the skin-friendly hydrogel is arranged on the bottom of the pure cotton spunlace nonwoven fabric.

[0062] When applied: the hydrogel ratio is 1:1. Magnesium sulfate has anti-inflammatory effects and can help reduce the inflammatory response around the wound. By reducing inflammation, magnesium sulfate helps reduce the redness, swelling and pain around the pressure sore, thereby creating an environment more conducive to healing. The skin absorbs magnesium sulfate to help dilate blood vessels, which can increase blood flow to the damaged area. Better blood circulation brings more oxygen and nutrients, which helps repair and heal the wound.

[0063] Embodiment 2:

[0064] Embodiment 2 is substantially the same as Embodiment 1, except that:

[0065] A method for preparing a blood-activating and stasis-removing dressing, comprising the following steps:

[0066] The first step is to evenly sprinkle EVAL powder on the prepared PP spunbond fabric, then heat the powder to melt it and introduce it into the PE breathable film. The hot melt adhesive is infiltrated on the surface of the two layers of materials, and then the laminating machine is used to pressurize the hot melt adhesive to solidify it in a short time, so that the PP spunbond fabric and the PE breathable film are bonded together to form a SF membrane composite material.

[0067] The second step is to make the SF membrane composite material into an open cloth bag, and then fill 10g of iron powder and 2g of carbon powder into the cloth bag to obtain a chemical hot compress bag, and then seal the chemical hot compress bag and compound it with the pure cotton spunlace nonwoven fabric, and then compound a layer of flash nonwoven fabric on the top of the pure cotton spunlace nonwoven fabric;

[0068] Step 3: first take 10g of polyvinyl alcohol and place it in 40g of deionized water, heat and ultrasonically treat it for 5min to obtain a PVA solution for use, then take 10g of carboxymethyl chitosan and place it in 40g of deionized water to obtain a carboxymethyl chitosan solution for use, then take 30g of magnesium sulfate and place it in 40℃ warm water to dissolve to obtain a magnesium sulfate solution, then take 15ml of the PVA solution and the carboxymethyl chitosan solution respectively, mix and stir evenly, then add 0.5ml of magnesium sulfate solution and ultrasonically treat it for 5min, then pour it into a mold, and then condense it for 12h to form it, to obtain a skin-friendly hydrogel;

[0069] Step 4: The skin-friendly hydrogel is adhered to the bottom of the pure cotton spunlace nonwoven fabric to obtain a blood-activating and blood-stasis-removing dressing.

[0070] When used: the ratio of 10g iron powder to 2g carbon powder makes the specific heat capacity of the reduced iron powder 460J / (kg·℃), which is slightly lower than the specific heat capacity of activated carbon 840J / (kg·℃). The higher the content of reduced iron powder in the mixed powder, the lower the overall specific heat capacity of the chemical heating agent, and the less heat is required to raise the temperature of the mixed powder by the same amount, making it easier to heat up. Select "10ml, 10% PVA solution, 10% carboxymethyl chitosan solution, 0.5ml, 30% magnesium sulfate solution, 12h molding". The molding is fast and not easy to produce precipitation. The common area of ​​pressure sores is about 4cm 2 , select the above values, the production area completely covers the wound, and it is not easy to cause material waste.

[0071] Embodiment 3:

[0072] Embodiment 3 is substantially the same as Embodiment 1, except that:

[0073] like Figures 2 to 3 As shown, the chemical heating pack quickly heated up to 51°C at an average heating rate of 2.3°C / min within 15 minutes, wherein the real-time heating rate continued to decrease with the passage of time, and then the temperature was maintained in the range of 51-52°C for 38 minutes, and the heating rate in this stage was about 0°C / min. Then the chemical heating pack began to cool down, and gradually cooled down to room temperature with a heating rate of negative value, absolute value first, increasing and then decreasing to zero. The chemical hot compress pack was sealed and then composited with the pure cotton spunlace nonwoven fabric, specifically: the upper layer was pure cotton spunlace nonwoven fabric, the middle chemical hot compress pack, and the lower layer was pure cotton spunlace nonwoven fabric, and the upper and lower layers of pure cotton spunlace nonwoven fabric wrapped the chemical hot compress therein; 10.0g of iron powder and 2.0g of carbon powder were taken respectively, and mechanical perforated and packaged under normal temperature conditions, with an average heating rate of 10.1°C / min, a temperature of 45.6°C, and a continuous heating time of 186 minutes.

[0074] When used: the chemical hot compress pack takes 4 minutes to reach the appropriate temperature, the heating rate is 10.1℃ / min, the heating time is 186 minutes, and the touch changes from granular to powdery after the heating efficiency reaction is completed, which can be used to identify whether the reaction is complete. This design is to adapt to the current routine nursing needs of 4 to 5 times a day, with a hot compress time of 3 hours. It can maintain normal hot compress temperature and ensure the hot compress time. Hot compress temperature controlled at 40-50℃ is more conducive to recovery.

[0075] Embodiment 4:

[0076] Embodiment 4 is substantially the same as Embodiment 1, except that:

[0077] A blood-activating and stasis-removing dressing is prepared by the preparation method of the blood-activating and stasis-removing dressing, and comprises a flash-steamed nonwoven fabric, a pure cotton spunlace nonwoven fabric, a hot compress pack and a skin-friendly hydrogel. The flash-steamed nonwoven fabric is arranged on the top of the pure cotton spunlace nonwoven fabric, and the hot compress pack is embedded in the pure cotton spunlace nonwoven fabric. The hot compress pack is made of PP, PE and EVAL and mechanically stretched after adding a porogen CaCO3 to control the pore structure, so as to ensure the timely and quantitative dripping of exudate and the long-term stable heat release of the hot compress pack. The skin-friendly hydrogel is arranged on the bottom of the pure cotton spunlace nonwoven fabric, and the pure cotton spunlace nonwoven fabric has the same length and width as the flash-steamed nonwoven fabric, and the length and width of the pure cotton spunlace nonwoven fabric is greater than the length and width of the skin-friendly hydrogel. The pure cotton spunlace nonwoven fabric and the flash-steamed nonwoven fabric are 15 cm×15 cm squares, and the magnesium sulfate skin-friendly hydrogel is 5×5 cm squares.

[0078] When applied: Pure cotton spunlace nonwoven fabric is degreased. During the degreasing process, impurities such as fat and wax in cotton are removed, and the surface of cotton fibers becomes cleaner and smoother, making it easier for water to penetrate into the fiber, thereby increasing the water absorption of cotton fibers and making them more suitable for textiles and other applications that require good water absorption. The chemical structure of cotton fibers contains a large number of polar groups (such as hydroxyl groups), which can form hydrogen bonds with water molecules, thereby giving cotton fibers good hydrophilicity and hygroscopicity. Spunlace nonwoven fabrics are materials composed of a porous structure formed by the three-dimensional random arrangement of fibers. They have a large specific surface area and more capillary channels, which are conducive to the adsorption and transmission of water molecules. At the same time, due to the large number of gaps and channels between fibers, water molecules can quickly diffuse into the interior of the fiber web, thereby improving the overall hygroscopicity.

[0079] Embodiment 5:

[0080] Embodiment 5 is substantially the same as Embodiment 1, except that:

[0081] The bottom of the pure cotton spunlace nonwoven fabric is located on the outer side of the skin-friendly hydrogel and is surrounded by an annular strap for fixing the dressing on the wrist or ankle.

[0082] Embodiment 6:

[0083] Embodiment 6 is substantially the same as Embodiment 1, except that:

[0084] Comparative classification of phlebitis severity after treatment with magnesium sulfate skin-friendly hydrogel (n / %) is shown in the following table

[0085]

[0086] Comparison of adverse reaction rates after using magnesium sulfate hydrogel (n / %) is shown in the following table

[0087]

[0088] The comparison of the pain level of patients after using the blood-activating and stasis-removing dressing for 30 minutes (n / %) is shown in the following table.

[0089]

[0090] Comparison of wound healing degree between the two groups (n / %) is shown in the following table.

[0091]

[0092] From the comparison of the data in the above table, it can be seen that the use of dressings of this product can effectively improve the healing of patients' wounds and reduce their pain.

[0093] The above description is only a preferred embodiment of the present invention, and the protection scope of the present invention is not limited to the above embodiment. Any equivalent modifications or changes made by ordinary technicians in this field based on the contents disclosed by the present invention should be included in the protection scope recorded in the claims.

Claims

1. A method for preparing a blood-activating and blood-stasis-removing dressing, characterized in that: The preparation method of the blood-activating and blood-stasis-removing dressing comprises the following steps: The first step is to evenly sprinkle EVAL powder on the PP spunbond fabric, and then laminate the side of the PP spunbond fabric sprinkled with EVAL powder with the PE spunbond film to obtain a SF film composite material; The second step is to make the SF membrane composite material into an open cloth bag, then fill the cloth bag with an appropriate amount of iron powder and carbon powder and seal it to obtain a chemical hot compress bag, then compound the chemical hot compress bag into the pure cotton spunlace nonwoven fabric, and then compound a layer of flash nonwoven fabric on the top of the pure cotton spunlace nonwoven fabric; Step 3: First, prepare a PVA solution and a carboxymethyl chitosan solution respectively, then take an appropriate amount of the PVA solution and the carboxymethyl chitosan solution and mix them evenly, then add an appropriate amount of magnesium sulfate solution and stir evenly, and condense and form after standing to obtain a skin-friendly hydrogel; Step 4: The skin-friendly hydrogel is adhered to the bottom of the pure cotton spunlace nonwoven fabric to obtain a blood-activating and blood-stasis-removing dressing.

2. The method for preparing a blood-activating and stasis-removing dressing according to claim 1, characterized in that: The EVAL powder is first evenly sprinkled on the PP spunbond fabric, and then the side of the PP spunbond fabric sprinkled with the EVAL powder is laminated with the PE spunbond film to obtain the SF membrane composite material. Specifically, the EVAL powder is first evenly sprinkled on the prepared PP spunbond fabric, and then the powder is melted by heating and introduced into the PE breathable film, the hot melt adhesive is infiltrated into the surfaces of the two layers of materials, and then a laminating machine is used to pressurize the hot melt adhesive to solidify it in a short time, so that the PP spunbond fabric and the PE breathable film are bonded together to form the SF membrane composite material.

3. The method for preparing a blood-activating and stasis-removing dressing according to claim 1, characterized in that: In the second step, the appropriate amount of iron powder and carbon powder is specifically: the mass percentage of iron powder to carbon powder is 5-20: carbon powder is 1-10.

4. The method for preparing a blood-activating and stasis-removing dressing according to claim 2, characterized in that: In the second step, the chemical hot compress pack is compounded in the pure cotton spunlace nonwoven fabric, specifically: the upper layer is pure cotton spunlace nonwoven fabric, the middle chemical hot compress pack, and the lower layer is pure cotton spunlace nonwoven fabric, and the upper and lower layers of pure cotton spunlace nonwoven fabric wrap the chemical hot compress therein.

5. The method for preparing a blood-activating and stasis-removing dressing according to claim 3, characterized in that: The chemical hot compress pack has a heating rate of 8°C / min-14°C / min, a temperature of 31°C-65°C, and a continuous heating time of 140 minutes-201 minutes.

6. The method for preparing a blood-activating and stasis-removing dressing according to claim 1, characterized in that: The pure cotton spunlace nonwoven fabric has the same length and width as the flash-spun nonwoven fabric, and the length and width of the pure cotton spunlace nonwoven fabric are greater than the length and width of the skin-friendly hydrogel.

7. The method for preparing a blood-activating and stasis-removing dressing according to claim 6, characterized in that: The pure cotton spunlace nonwoven fabric and the flash-steamed nonwoven fabric are both in the shape of a 15 cm×15 cm square, and the magnesium sulfate skin-friendly hydrogel is in the shape of a 5×5 cm square.

8. The method for preparing a blood-activating and stasis-removing dressing according to claim 1, characterized in that: In the third step, the mass fraction ratio of the PVA solution is 5%-20%, the mass fraction ratio of the carboxymethyl chitosan solution is 5%-20%, and the mass fraction ratio of the magnesium sulfate solution is 10%-40%; The volume ratio of the PVA solution, the carboxymethyl chitosan solution and the magnesium sulfate solution is 2-15:2-15:0.1-1.

9. The method for preparing a blood-activating and stasis-removing dressing according to claim 8, characterized in that: The preparation method of the PVA solution is as follows: 5-15g of polyvinyl alcohol is placed in 40g of deionized water, and heated and ultrasonically treated for 5 minutes to obtain a PVA solution; The preparation method of the carboxymethyl chitosan solution is as follows: then taking 5-15g of carboxymethyl chitosan and placing it in 40g of deionized water to obtain a carboxymethyl chitosan solution; The preparation method of the magnesium sulfate solution is as follows: 10-50 g of magnesium sulfate is dissolved in 40° C. warm water to obtain a magnesium sulfate solution; The step of standing still and then condensing to form the skin-friendly hydrogel is as follows: the magnesium sulfate solution is ultrasonically treated for 5 minutes, poured into a mold, and then condensed for 12 hours to form the skin-friendly hydrogel.

10. A blood-activating and blood-stasis-removing dressing, characterized in that: The blood-activating and stasis-removing dressing is prepared by the preparation method of the blood-activating and stasis-removing dressing described in claim 1, and the blood-activating and stasis-removing dressing comprises a flash-steamed nonwoven fabric, a pure cotton spunlace nonwoven fabric, a hot compress pack and a skin-friendly hydrogel, wherein the flash-steamed nonwoven fabric is arranged on the top of the pure cotton spunlace nonwoven fabric, the hot compress pack is embedded in the pure cotton spunlace nonwoven fabric, and the skin-friendly hydrogel is arranged on the bottom of the pure cotton spunlace nonwoven fabric.

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