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Stem cells for clinical and commercial uses

A stem cell, pluripotent stem cell technology, used in, for example, diagnosis, obtaining new sources of stem cells, cell composition, engineering and biotechnology fields, and can solve problems related to stem cell collection and recovery technology

Inactive Publication Date: 2006-11-08
BOARD OF RGT THE UNIV OF TEXAS SYST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] The present invention solves the problems associated with current stem cell collection and recovery techniques by providing new and improved methods of obtaining stem cells at high yields without destroying the tissue of origin and methods of using these stem cells

Method used

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  • Stem cells for clinical and commercial uses
  • Stem cells for clinical and commercial uses
  • Stem cells for clinical and commercial uses

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Embodiment Construction

[0031] While making and using various embodiments of the invention are discussed in detail below, it should be appreciated that the invention provides many inventive concepts that can be embodied in a wide variety of contexts. The specific aspects and embodiments discussed herein are merely illustrative of making and using the invention, and do not limit the scope of the invention.

[0032] In general, stem cells are pluripotent cells in an unspecialized (eg, undifferentiated) state that can give rise to one or more types of unspecialized cells. A key identifying characteristic of a stem cell is the ability to exhibit self-renewal, or to generate more of itself; thus, a self-sustaining cell. Furthermore, as used herein, stem cells are unspecialized cells capable of proliferating (replicating many times), self-sustaining and producing large numbers of specialized functional progeny, and capable of regenerating tissue after injury.

[0033] One role of stem cells is to replace ...

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Abstract

Methods for accumulating, recruiting and retrieving stem cells from a body cavity space of an adult mammal are disclosed, in addition to compositions and cells in accordance with the present invention. In accordance with another aspect of the present invention, a method of obtaining a new source of stem cells is provided by implanting a foreign object in a body cavity space of a mammal and collecting those stem cells resulting from implantation. Further in accordance with the present invention, a method for providing to a subject in need thereof one or more stem cells of the present invention is identified by retrieving stem cells for a body cavity space of a mammal after implanting a foreign object, manipulating the stem cells and introducing the stem cells into the subject in need thereof.

Description

[0001] Statement Regarding Federally Supported Research or Development Projects [0002] This application was funded in part by National Institutes of Health grant number EB-00287. The United States Government may have certain rights in this invention. [0003] This application claims priority to US Provisional Patent Application Serial No. 60 / 474,020, filed May 29,2003. Background of the invention [0004] The present invention relates to the general field of cell physiology, and more particularly to the development and production of compositions of clinically viable stem cells for medical applications such as diagnosis, screening, testing, treatment and rehabilitation and cells for commercial applications such as screening, testing and bioengineering and methods. [0005] Because of their plasticity and potential use to replace diseased, damaged or aging tissues and organs, stem cell research offers a new panacea for patients suffering from cancer, spinal cord injuries, st...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12N5/00A61K35/12A61K35/15A61K35/30A61K35/32A61K35/34A61K35/35A61K35/545C12N5/074
CPCA61K35/15A61K35/30A61K35/32A61K35/34A61K35/35A61K35/545C12N5/0607C12N2506/03
Inventor 唐力平罗伯特·H·汉森
Owner BOARD OF RGT THE UNIV OF TEXAS SYST
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