Device for separating blood fibrin

Abstract

The utility model relates to the field of serum sampling equipment, and discloses a device for separating blood fibrin, which comprises a separation unit, the separation unit comprises a separation cover, the separation cover comprises a separation cover body, the separation cover body comprises an insertion part capable of being inserted into a centrifugal tube, the insertion part is clamped with a filter screen, and the aperture of the filter screen is smaller than the diameter of the fibrin. Through matching of the insertion part and the filter screen, the device is directly placed into a centrifugal tube to filter fibrous protein, the needle head is prevented from being blocked, meanwhile, the pollution risk is reduced without replacing a cover, the rubber sealing layer can be punctured and pushed away, the sampling needle is prevented from being blocked, and the sample treatment efficiency and safety are improved.

Description

Technical Field

[0001] The utility model relates to the field of serum sampling equipment, in particular to a device for separating blood fibrin. Background Art

[0002] Serum refers to the yellowish transparent liquid separated from plasma by removing fibrinogen after blood coagulation, or refers to plasma from which fibrinogen has been removed. Its main functions are to provide basic nutrients, hormones and various growth factors, binding proteins, contact-promoting and stretching factors to prevent cells from mechanical damage, and to play a certain protective role on cells in culture. In the process of medical operation, it is necessary to collect blood from patients and separate the serum from the collected blood so that biochemical, immune, and hormonal tests can be performed through the serum. When separating serum, the collected whole blood needs to be left to stand for 30-60 minutes. After the blood coagulates, the serum is separated by a centrifuge. However, in practice, some fibrin will still exist on the top of the serum. When the sampling needle is inserted into the serum, the fibrin will enter the needle of the sampling needle, which will block the needle of the sampling needle and also cause inaccurate blood sample test results.

[0003] In order to optimize the serum collection process and solve the problem of fibrin clogging the sampling needle, a Chinese patent with application number CN201922436877.6 proposes a serum extraction device, which isolates fibrin by setting a filter structure on the cover. However, since a vacuum sampling tube is required for sampling, the centrifuge tube or cover needs to be replaced between sampling and centrifugation, there is a risk of sample contamination. Utility Model Content

[0004] The utility model aims to provide a device for separating blood fibrin, so as to separate the fibrin in serum and prevent the fibrin from entering the needle, causing the needle to be blocked or affecting the test result.

[0005] To achieve the above-mentioned purpose, the utility model adopts the following technical scheme: a device for separating blood fibrin, comprising a separation unit, the separation unit comprising a separation cover, the separation cover comprising a separation cover body, the separation cover body comprising an insertion portion that can be inserted into a centrifuge tube and a mounting portion connected to the needle head of a sampling needle, the insertion portion being clamped with a filter screen extending to the mounting portion, and the pore size of the filter screen being smaller than the diameter of the fibrin.

[0006] The beneficial effects of this solution are: 1. An insertion portion is provided through the separation cover. After centrifugation is completed, the separation cover can be inserted into the centrifuge tube through the insertion portion, and the fibrin is filtered through the filter screen, thereby preventing the fibrin from entering the needle tip of the sampling needle and causing needle clogging; 2. There is no need to replace the cover body, reducing the probability of sample contamination; 3. Generally speaking, a rubber sealing layer is provided on the cover body of the centrifuge tube. When the sampling needle is inserted into the sampling needle for sampling, the rubber sealing layer may enter the needle tip of the sampling needle and cause clogging of the sampling needle. The rubber sealing layer provided on the cover body of the centrifuge tube is punctured and pushed away by the insertion portion, which can effectively prevent the rubber sealing layer from clogging the sampling needle.

[0007] Furthermore, the insertion portion is fixedly provided with a plurality of connection portions, and the mounting portion is fixedly connected to the connection portions.

[0008] Furthermore, the inserting portion is conical, the cone includes a tip and a wide end, the wide end is provided with an annular groove, and the filter screen is a cylindrical member arranged between the annular groove and the mounting portion.

[0009] Beneficial effects: 1. The design of the tapered insertion part makes the insertion of the centrifuge tube smoother, the tip part is easy to enter, and the wide end fits more closely with the inner wall of the centrifuge tube. In addition, the filter screen fixing method at the annular groove improves the overall sealing performance, reduces the risk of leakage during centrifugation, and also enhances the stability of the device; 2. The cylindrical filter screen arranged between the annular groove and the mounting part is not only convenient for installation and replacement, but also ensures that the fixed position of the filter screen remains unchanged during the insertion process through the limitation of the annular groove, avoids the displacement or falling off of the filter screen, and improves the filtration efficiency and reliability; 3. The tapered design and the independent cylindrical structure of the filter screen make cleaning more convenient, and the filter screen can be more easily disassembled and thoroughly cleaned, reducing the risk of contamination, maintaining the cleanliness of the experiment and the convenience of reuse.

[0010] Furthermore, the number of the connecting parts is three and they are centrally symmetrically arranged outside the annular groove.

[0011] Beneficial effects: The three connecting parts arranged symmetrically along the center can ensure that a more balanced stress state is formed between the separation cover and the centrifuge tube after installation, which can maintain the stability of the device, prevent displacement or falling off, and enhance the stability of the overall structure; the three-point fixing method can distribute the pressure more evenly, ensure the sealing of the interface between the centrifuge tube and the separation cover, effectively prevent sample leakage, protect the experimental environment from pollution, and also ensure the integrity of the sample and the accuracy of the analysis results.

[0012] Furthermore, it also includes a sampling unit, which includes a sampling needle, and the sampling needle sleeve is arranged inside the separation cover.

[0013] Beneficial effects: 1. The sleeve design of the separation cover makes the same set of equipment suitable for continuous sampling of multiple samples, without the need to frequently disassemble and assemble the separation cover, which improves work efficiency, reduces losses during operation, and extends the service life of the device.

[0014] Furthermore, an opening is provided at one end of the separation cover body away from the insertion part, and a sealing membrane is provided at the opening; 2. The filter is limited at both ends by the annular groove and the sampling needle head. At the same time, a connecting part is provided on the outer ring of the filter to ensure that the filter will not be offset during the insertion process, allowing impurities to enter the filter and affect the detection results.

[0015] Beneficial effects: 1. The setting of the sealing film effectively blocks external dust and other contaminants from entering the interior of the separation cover, protects the blood sample from contamination, and ensures the accuracy and reliability of the experimental results; 2. When the separation cover is correctly inserted into the centrifuge tube, a closed sealed space is formed between the centrifuge tube and the separation cover. During the sampling stage, when the sampling needle is inserted through the sealing film and begins to draw, a negative pressure will be formed inside the separation cover. This negative pressure effect significantly speeds up the speed at which the serum flows through the filter into the sampling needle, thereby greatly improving the sampling efficiency, shortening the experimental time, and reducing the workload of the operator; 3. The design of the sealing film makes the use of the entire device more convenient, without the need for additional sealing steps, and the seal can be formed by directly puncturing with the sampling needle, which not only ensures the sealing of the sample, but also simplifies the operation process, improves the fluency of the experiment and the convenience of operation; 3. The use of the sealing film also avoids sample disturbance caused by multiple opening and closing of the container during the sampling process, which is conducive to maintaining the original state of the sample. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a three-dimensional diagram of the separation cover body of the utility model;

[0017] Figure 2 This is a cross-sectional view of an embodiment of the utility model;

[0018] Figure 3 A 3D diagram of a vacuum sampling tube. DETAILED DESCRIPTION

[0019] The following is further described in detail through specific implementation methods:

[0020] The reference numerals in the drawings of the specification include: cell layer 101 , serum layer 102 , impurity layer 103 , tube body 11 , cover body 12 , fixing member 121 , sealing member 122 , sampling needle 2 , mounting portion 31 , annular groove 321 , connecting portion 322 , and inserting portion 32 .

[0021] Example 1

[0022] Embodiment 1 is basically as attached Figure 1-3 As shown, Figure 1-3 The device for separating blood fibrin shown in the figure comprises a sampling unit and a separation unit. The sampling unit can refer to the sampler of application number CN200910000075.9, comprising a syringe and a sampling needle 2. The sampling needle 2 is connected to the syringe, so that the sample is extracted through the sampling needle 2 by moving the syringe piston. The difference is that the sampling needle 2 is a straight needle. The separation unit comprises a vacuum sampling tube and a separation cover. Figure 3 As shown, the commonly used blood sampling device is a vacuum sampling tube, which includes a tube body 11 and a cover body 12. The cover body 12 includes a sealing member 122 and a fixing member 121. The cover body 12 is covered on the open end of the tube body 11 through the fixing member 121. The sealing member 122 is located between the tube body 11 and the fixing member 121 so that a certain negative pressure exists in the tube body 11. When sampling, the blood sampling needle is connected to the blood vessels of the human body to collect whole blood. Figure 2 After standing and centrifuging, the whole blood is divided into a cell layer 101, a serum layer 102 and an impurity layer 103.

[0023] The separation cover includes a separation cover body and a filter screen. Figure 1 As shown, the separation cover body includes an integrally formed mounting portion 31, a connecting portion 322 and an insertion portion 32 from top to bottom. The mounting portion 31 is sleeved on the outside of the needle head of the sampling needle 2. The insertion portion 32 is conical, and the cone includes a tip and a wide end. The wide end is provided with an annular groove 321, and the taper range is 15-45°, preferably 30°, so as to reduce the length of the insertion portion 32 while ensuring the sharpness of the puncture, and avoid the insertion portion 32 being too long and contacting the bottom of the vacuum sampling tube, resulting in damage to blood cells, and causing misjudgment of hemolysis. The filter is a cylindrical member that is clamped in the annular groove 321 and extends to the mounting portion 31.

[0024] The specific implementation process is as follows:

[0025] When in use, first, the whole blood is allowed to stand and centrifuge to precipitate the serum, then the filter is clamped into the separation cover body, ensuring that the lower end of the filter is clamped into the annular groove 321, and the installation of the separation cover is completed. Then, the separation cover is clamped onto the needle of the sampling needle 2, so that the stability of the filter is ensured by the structure of fixing at both ends and supporting in the middle, and the filter is prevented from being deflected during the insertion of the separation cover, causing impurities to enter the separation cover and then enter the sampling needle 2. Finally, the needle and the separation cover are inserted into the vacuum sampling tube together, and the impurities in the impurity layer 103 are isolated by the filter outside the separation cover, and extracted by a syringe to speed up the filtration speed of the serum until the sampling of the serum is completed, and the sampling unit is separated from the separation cover, so as to carry out the inspection. After the sampling is completed, the separation cover and the filter can be cleaned and disinfected for subsequent use.

[0026] Example 2

[0027] On the basis of the embodiment, a sealing film is covered on the top end of the separation cover mounting portion 31, and the sealing film includes a fixing portion, which is threadedly connected to the mounting portion 31. When in use, the sealing film is first covered on the mounting portion 31 of the separation cover, and then the separation cover is inserted into the vacuum sampling tube after centrifugation to complete the separation of impurities and serum and wait for the serum to be filtered into the separation cover, and then sampling is performed through the sampling unit. Compared with Example 1, this solution can be used for automatic sampling equipment to reduce the workload of inspection personnel. At the same time, the same sample can be sampled multiple times without worrying about sample contamination.

[0028] The above is only an embodiment of the utility model, and the common knowledge such as the known specific technical solutions and / or characteristics in the solution is not described in detail here. It should be pointed out that the technical means for solving the problems in the above-mentioned embodiments of the utility model can be used in combination to solve multiple technical problems at the same time. For those skilled in the art, several deformations and improvements can be made without departing from the technical solution of the utility model, which should also be regarded as the protection scope of the utility model, and these will not affect the effect of the implementation of the utility model and the practicality of the patent. The scope of protection required by this application shall be based on the content of its claims, and the specific implementation methods and other records in the specification can be used to interpret the content of the claims.

Claims

1. A device for separating blood fibrin, characterized in that: It includes a separation unit, which includes a separation cover, which includes a separation cover body, which includes an insertion part that can be inserted into a centrifuge tube and a mounting part connected to the needle head of a sampling needle, and the insertion part is clamped with a filter screen extending to the mounting part, and the pore size of the filter screen is smaller than the diameter of the fibrin.

2. The device for separating blood fibrin according to claim 1, characterized in that: The inserting part is fixedly provided with a plurality of connecting parts, and the mounting part is fixedly connected with the connecting parts.

3. The device for separating blood fibrin according to claim 2, characterized in that: The inserting portion is conical, the cone includes a tip and a wide end, the wide end is provided with an annular groove, and the filter screen is a cylindrical member arranged between the annular groove and the mounting portion.

4. The device for separating blood fibrin according to claim 3, characterized in that: The number of the connecting parts is 3 and they are centrally symmetrically arranged outside the annular groove.

5. The device for separating blood fibrin according to claim 4, characterized in that: It also includes a sampling unit, which includes a sampling needle, and the sampling needle sleeve is arranged inside the separation cover.

6. The device for separating blood fibrin according to claim 5, characterized in that: An opening is arranged at one end of the separation cover body away from the insertion part, and a sealing film is arranged at the opening.

Images