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Skin care composition

a technology for skin care and composition, applied in the field of skin care composition, can solve the problems of unsatisfactory long-term solution for patients, and high cost for patients and/or health services

Inactive Publication Date: 2020-01-30
ISN PHARMA SP ZOO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0011]The present invention relates to skin care compositions comprising the extract from Kalanchoe daigremontiana for administration to human skin. The compositions are therapeutically effective for both skin conditioning and combating skin disorders.

Problems solved by technology

However, steroids are undesirable for a number of reasons: they are expensive for the patient and / or health services and often lead to serious side effects which include inter alia: systemic hormonal changes, skin atrophy, eczema, steroid acne, erythema, vascular purpura, telangiectasia, skin irritation, e.g. burning sensation, reddening, extreme dryness and sometimes bacterial or mycotic superinfections.
However, these treatments fail to provide a sufficient long term solution for patients; they reduce the superficial appearance of squama on the surface of psoriatic plaque but do not prevent or alleviate regenerating lesions or allow the skin to heal fully.
Further, by using such preparations, skin cannot be exposed to sunlight.
However, there is no indication that such extracts from either of these plants would be useful in the health of humans or be useful in the treatment of a particular human condition.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0077]1-30% w / w of the extract or juice from Kalanchoe daigremontiana

[0078]4-20% w / w of the glycerol monostearate

[0079]4-28% w / w of the beeswax

[0080]35-75% w / w of the demineralized water

[0081]The extract from Kalanchoe daigremontiana is an aqueous extract derived from any part of the plant, preferably the leaves and / or the juice from the leaves and / or juice from the plant or other parts of the plant biomass, such as the stalk.

[0082]The production process starts with preparation of glycerol monostearate and beeswax (the fats) which are heated up to the temperature of 30-75 degrees C. and stirred until the mixture becomes smooth.

[0083]The demineralized water is heated up to 30-75 degrees C. The fats are then added to the heated demineralized water stirred and homogenised until the mixture is smooth.

[0084]The mixture of fats and water is cooled to a temperature of 20-30 degrees C.

[0085]The extract of Kalanchoe daigremontiana is added to the mixture, stirred and homogenised to result i...

example 2

[0086]1-30% w / w of the extract or juice from Kalanchoe daigremontiana

[0087]4-20% w / w of the glycerol monostearate

[0088]4-28% w / w of the beeswax

[0089]35-75% w / w of the demineralized water

[0090]0.5-1% w / w of phenoxyethanol

[0091]The cream production process is completed as per Example 1 with the exception that in the final phase, after the extract of Kalanchoe daigremontiana is added and stirred, a preservative (phenoxyethanol) is added. The resulting mixture is then stirred and homogenised.

example 3

[0092]1-30% w / w of the extract or juice from Kalanchoe daigremontiana

[0093]4-20% w / w of the glycerol monostearate

[0094]4-40% w / w of the coconut oil

[0095]35-75% w / w of the demineralized water

[0096]The cream production process is as provided in Example 1 but using the alternative combination of fats as specified above.

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Abstract

The present invention relates to methods of skin care or treating dermal conditions characterized by itching, skin redness, skin roughness, keratosis and squama, the method comprising: applying a composition for topical administration comprising a therapeutically effective amount of Kalanchoe daigremontiana extract or juice to an affected area. The compositions are therapeutically effective for hydrating and conditioning the skin and are shown to be clinically effective at treating dermal conditions or skin disorders, in particular, psoriasis, atopic dermatitis or allergic contact dermatitis.

Description

RELATED APPLICATIONS[0001]This application is a divisional of application Ser. No. 15 / 774,670, which is a national phase application filed under 35 USC § 371 of PCT Application No. PCT / IB2016 / 056808 with an International filing date of Nov. 11, 2016, which claims priority of GB Patent Application GB1613401.7 filed Aug. 3, 2016 and Polish Patent Application PL414758 filed Nov. 12, 2015. Each of these applications is herein incorporated by reference in its entirety for all purposes.FIELD OF THE INVENTION[0002]This invention relates to a skin care composition comprising extract, for example the juice, from Kalanchoe daigremontiana for topical administration to human skin. In particular, the invention relates to a method of making such a composition and to cosmetic and medical uses thereof.BACKGROUND[0003]In the field of skin care, a wide variety of products have been developed and commercialised for enhancing skin condition.[0004]Such products are typically formulated as gels, creams, ...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61K36/41A61K8/34A61K8/92A61K8/49A61Q19/00A61K8/97A61K36/185A61K9/00A61K47/14A61K9/06A61K8/9789A61P37/00A61P17/06A61K9/70A61K47/10A61K47/22A61K47/44
CPCA61K36/185A61P37/00A61K47/14A61Q19/007A61P17/06A61K47/22A61K9/06A61K36/41A61K8/9789A61K47/10A61K9/7023A61K8/97A61K8/4946A61K2800/87A61K47/44A61K8/342A61K9/0014A61K8/927A61Q19/00A61K8/9794A61K2300/00
Inventor NOWAK, SYLWIA
Owner ISN PHARMA SP ZOO
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