Sterilization composition

Abstract

The present invention relates to a sterilization composition, and belongs to the field of pesticide combination. The active ingredients of the sterilization composition are formed through the combination of cyflufenamid and a anilinopyrimidine compound selected from cyprodinil, mepanipyrim and pyrimethanil, wherein the weight percentage ratio of the two active ingredients is 90:1-1:90, preferably 50:3-5:65. The total weight percentage of the active ingredients in the sterilization composition is 1-90%, preferably 5-75%, the balance is a pesticidally-allowed and pesticidally-acceptable assistant component. The sterilization composition is prepared into wettable powder, suspending agent, soluble liquor, aqueous emulsion, emulsifiable concentrate, water dispersible granule and granule through the known method. The sterilization composition provided by the present invention is mainly used for controlling fungal diseases of crops such as grains, cottons, oil, fruits, vegetables and flowers.

Description

technical field

[0001] The present invention relates to the technical field of pesticide compounding, in particular to a bactericidal composition that uses any one of cyflufenamid, cyprodinil, azoxystrobin or pyrimethanil as active ingredients for dual compounding. Background technique

[0002] Cyflufenamide is a fungicide with a new parent structure developed by Nippon Soda Corporation. Its chemical structural formula is as follows:

[0003]

[0004] It has excellent effects and characteristics on various vegetables and wheat powdery mildew and peach ash, and has the same activity on benzimidazole, imidazole, methoxyacrylate resistant bacteria and sensitive bacteria. Cyflufenamide has extremely low toxicity to humans and animals, and has no impact on the next generation. The teratogenicity and mutagenicity tests are all negative, and there is no irritation or allergy to eyes and skin in production. In addition, this agent will not affect the environment and beneficial o...

Examples

example 1

[0043] (1) Experimental object:

[0044] Cucumber downy mildew pathogen was isolated and purified from cucumber downy mildew diseased leaves in Shouguang cucumber greenhouse in Shandong Province, and cultured and preserved on PDA slopes in a 4°C refrigerator.

[0045] Test medium:

[0046] PDA medium: potato 200g, glucose 20g, agar 20g, water 1000ml.

[0047] AEA medium: yeast powder 5g / L, glycerol 20mL / L, MgSO 4 0.25g / L, NaNO 3 6g / L, KCl0.5g / L, KH 2 PO 4 1.5g / L, agar powder 20g / L, deionized water 1L.

[0048] (2) Experimental medicine:

[0049] 90% cyflufenamide technical product, Germany Bayer Crop Science Co., Ltd., 99% cyprodinil technical product, Japan Ishihara Sangyo Co., Ltd.

[0050] Mix and match settings:

[0051] The content percentages of 19% cyflufenamide and cyprodinil are 3:16, 5:14, 7:12, 9:10, 11:8, namely 3%+16%, 5%+14%, 7% +12%, 9%+10%, 11%+8%, a total of 5 mixed combinations.

[0052] (3) Test method:

[0053] Toxicity determination of single ag...

example 2

[0071] Biological Assay Example 2: Indoor Toxicity Determination of Cyflufen and Azoxystrobin Compound on Cucumber Anthracnose Pathogen.

[0072] 97% azoxystrobin technical product, Lanzhou Tradewind Forest Fine Chemical Co., Ltd.

[0073] Cucumber anthracnose pathogen was isolated and purified from cucumber anthracnose-infected leaves in Shouguang cucumber shed, and cultured and preserved on PDA slant at 4°C refrigerator.

[0074] Toxicity assays for single-dose cycloflufen and azoxystrobin, EC 50 The values ​​were 3.07 mg / l and 7.42 mg / l, respectively.

[0075] Mix and match settings:

[0076] The content percentages of 17% fluflufenamide and azoxystrobin are 3:14, 5:12, 7:10, 9:8, 11:6, that is, 3%+14%, 5%+12%, 7%+ 10%, 9%+8%, 11%+6% total 5 mixing combinations.

[0077] Test method is the same as biological assay embodiment 1

[0078] Experimental results and analysis:

[0079] Table 3 Toxicity test of the combination of fluflufen and azoxystrobin against cucumber an...

example 3

[0085] Biological Assay Example 3: Indoor Toxicity Determination of Cyflufenamide and Pyrimethanil Compound to Cucumber Botrytis.

[0086] 98% pyrimethanil technical, Jiangsu Changlong Agrochemical Co., Ltd.

[0087] Cucumber gray mold fungus was isolated and purified from cucumber gray mold diseased leaves in Shouguang cucumber greenhouse in Shandong Province, and cultured and preserved on PDA slopes in a 4°C refrigerator.

[0088] Toxicity Assays for Single-Agent Cyflufenamide and Pyrimethanil, EC 50 The values ​​were 4.16 mg / l and 6.88 mg / l, respectively.

[0089] Mix and match settings:

[0090] The content percentages of 20% fluvafen and pyrimethanil are 4:16, 6:14, 8:12, 10:10, 12:8, that is, 4%+16%, 6%+14%, 8%+ 12%, 10%+10%, 12%+8% total 5 mixing combinations.

[0091] Test method is the same as biological assay embodiment 1

[0092] results and analysis:

[0093] Table 5 Combined toxicity of flufenamide and pyrimethanil compound against Botrytis cinerea

[0094]...

technical field

[0001] The present invention relates to the technical field of pesticide compounding, in particular to a bactericidal composition that uses any one of cyflufenamid, cyprodinil, azoxystrobin or pyrimethanil as active ingredients for dual compounding. Background technique

[0002] Cyflufenamide is a fungicide with a new parent structure developed by Nippon Soda Corporation. Its chemical structural formula is as follows:

[0003]

[0004] It has excellent effects and characteristics on various vegetables and wheat powdery mildew and peach ash, and has the same activity on benzimidazole, imidazole, methoxyacrylate resistant bacteria and sensitive bacteria. Cyflufenamide has extremely low toxicity to humans and animals, and has no impact on the next generation. The teratogenicity and mutagenicity tests are all negative, and there is no irritation or allergy to eyes and skin in production. In addition, this agent will not affect the environment and beneficial o...

Examples

example 1

[0043] (1) Experimental object:

[0044] Cucumber downy mildew pathogen was isolated and purified from cucumber downy mildew diseased leaves in Shouguang cucumber greenhouse in Shandong Province, and cultured and preserved on PDA slopes in a 4°C refrigerator.

[0045] Test medium:

[0046] PDA medium: potato 200g, glucose 20g, agar 20g, water 1000ml.

[0047] AEA medium: yeast powder 5g / L, glycerol 20mL / L, MgSO 4 0.25g / L, NaNO 3 6g / L, KCl0.5g / L, KH 2 PO 4 1.5g / L, agar powder 20g / L, deionized water 1L.

[0048] (2) Experimental medicine:

[0049] 90% cyflufenamide technical product, Germany Bayer Crop Science Co., Ltd., 99% cyprodinil technical product, Japan Ishihara Sangyo Co., Ltd.

[0050] Mix and match settings:

[0051] The content percentages of 19% cyflufenamide and cyprodinil are 3:16, 5:14, 7:12, 9:10, 11:8, namely 3%+16%, 5%+14%, 7% +12%, 9%+10%, 11%+8%, a total of 5 mixed combinations.

[0052] (3) Test method:

[0053] Toxicity determination of single ag...

example 2

[0071] Biological Assay Example 2: Indoor Toxicity Determination of Cyflufen and Azoxystrobin Compound on Cucumber Anthracnose Pathogen.

[0072] 97% azoxystrobin technical product, Lanzhou Tradewind Forest Fine Chemical Co., Ltd.

[0073] Cucumber anthracnose pathogen was isolated and purified from cucumber anthracnose-infected leaves in Shouguang cucumber shed, and cultured and preserved on PDA slant at 4°C refrigerator.

[0074] Toxicity assays for single-dose cycloflufen and azoxystrobin, EC 50 The values ​​were 3.07 mg / l and 7.42 mg / l, respectively.

[0075] Mix and match settings:

[0076] The content percentages of 17% fluflufenamide and azoxystrobin are 3:14, 5:12, 7:10, 9:8, 11:6, that is, 3%+14%, 5%+12%, 7%+ 10%, 9%+8%, 11%+6% total 5 mixing combinations.

[0077] Test method is the same as biological assay embodiment 1

[0078] Experimental results and analysis:

[0079] Table 3 Toxicity test of the combination of fluflufen and azoxystrobin against cucumber an...

example 3

[0085] Biological Assay Example 3: Indoor Toxicity Determination of Cyflufenamide and Pyrimethanil Compound to Cucumber Botrytis.

[0086] 98% pyrimethanil technical, Jiangsu Changlong Agrochemical Co., Ltd.

[0087] Cucumber gray mold fungus was isolated and purified from cucumber gray mold diseased leaves in Shouguang cucumber greenhouse in Shandong Province, and cultured and preserved on PDA slopes in a 4°C refrigerator.

[0088] Toxicity Assays for Single-Agent Cyflufenamide and Pyrimethanil, EC 50 The values ​​were 4.16 mg / l and 6.88 mg / l, respectively.

[0089] Mix and match settings:

[0090] The content percentages of 20% fluvafen and pyrimethanil are 4:16, 6:14, 8:12, 10:10, 12:8, that is, 4%+16%, 6%+14%, 8%+ 12%, 10%+10%, 12%+8% total 5 mixing combinations.

[0091] Test method is the same as biological assay embodiment 1

[0092] results and analysis:

[0093] Table 5 Combined toxicity of flufenamide and pyrimethanil compound against Botrytis cinerea

[0094]...

Images