A mask-type respiratory pathogen sampling device

Through the mask-type respiratory pathogen sampling device, the microporous spiral coil and refrigeration box design is used to solve the problems of low efficiency of lower respiratory pathogen collection and discomfort in the existing technology, and efficient and comfortable pathogen collection and biological activity maintenance are achieved. .

CN111803138BActive Publication Date: 2025-01-07刘思聪

Patent Information

Application Number
CN202010794594.3
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2020-08-10
Publication Date
2025-01-07
Estimated Expiration
2040-08-10

AI Technical Summary

Technical Problem

The existing respiratory infectious disease pathogen sampling methods are inefficient in pathogen collection at the breeding points of lower respiratory tract lesions, and the sampling process is not suitable for those who are sampled, especially when sampling in the nasopharynx.

Method used

A mask-type respiratory pathogen sampling device was designed, using microporous spiral coils to enrich the pathogens in the exhaled gas into the pathogen collection and preservation solution, and the exhaled gas introduced into the lungs through the mask for collection and collection, combining a refrigeration box and filtering. Membranes to maintain biological activity and prevent pathogens from escaping.

Benefits of technology

The enrichment of large quantities of lower respiratory tract pathogens was achieved, the collection efficiency and the comfort of the sampled person were improved, the biological activity of the pathogen was maintained, and a practical sampling tool was realized through simple structure and low cost.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention discloses a mask-type respiratory pathogen sampling device, comprising a mask, an air supply pipe, a collecting pipe, a pipe cover, an air dispersion coil, an exhaust pipe and a cold storage box, wherein the mask is provided with a one-way valve air inlet and an air outlet; the collecting pipe is detachably provided with a pipe cover, and an air dispersion coil and an exhaust pipe are inserted on the pipe cover, and the air dispersion coil runs through the bottom of the collecting pipe; one end of the air supply pipe is connected to the air outlet of the mask, and the other end is connected to the pipe mouth of the air dispersion coil; the collecting pipe is filled with pathogen collection and preservation liquid; the collecting pipe can be adaptively placed in the cold storage box. The innovative point of the present invention is that the mask intercepts the gas exhaled by the sampled person, introduces it into the air dispersion coil immersed in the sampling preservation liquid, and then exhausts the gas through the micropores on the spiral air dispersion coil, dissolving the pathogens carried in the bubbles in the pathogen collection and preservation liquid, so as to achieve the purpose of efficiently collecting respiratory pathogens.
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Description

Technical Field

[0001] The invention belongs to the technical field of pathogen sampling tools, and in particular relates to a mask-type respiratory pathogen sampling device. Background Art

[0002] At present, the sampling of pathogens of respiratory infectious diseases (such as new coronavirus, influenza virus, measles virus, tuberculosis bacillus, etc.) mostly uses swabs to scrape the mucosa of the oropharynx or nasopharynx, and then washes the virus on the swab for detection and analysis. However, this method has three disadvantages: first, since the lesions and breeding points of most pathogens of respiratory infectious diseases are in the lungs of the lower respiratory tract, the amount of pathogens retained on the mucosal walls of the oropharynx and nasopharynx of the upper respiratory tract is small, so there are not many pathogens that can be scraped; second, the surface area of ​​the swab head is very limited, and the mucosal cells and pathogens that it can adhere to are also very limited; third, in order to scrape the pathogens as much as possible, the swab must be extended as far as possible to the back of the upper respiratory tract for collection, but this will make the sampled person feel very uncomfortable, especially when using nasopharyngeal sampling. Therefore, it is urgent to invent a sampling tool that can collect a large number of pathogens discharged from the lesion breeding points of the lower respiratory tract without causing too much discomfort to the sampled person. Summary of the invention

[0003] In view of the above-mentioned deficiencies in the prior art, the present invention invents a mask-type respiratory pathogen sampling device.

[0004] In order to achieve the above object, the present invention adopts the following technical solution:

[0005] A mask-type respiratory pathogen sampling device comprises a mask, an air supply pipe, a collecting pipe, a pipe cover, an air dispersion coil and an exhaust pipe, wherein the mask is provided with an air inlet and an air outlet with a one-way valve; the collecting pipe is detachably provided with a pipe cover, and an air dispersion coil and an exhaust pipe are inserted on the pipe cover, and the air dispersion coil extends to the bottom of the collecting pipe; one end of the air supply pipe is connected to the air outlet on the mask, and the other end of the air supply pipe is connected to the pipe opening of the air dispersion coil on the pipe cover; the collecting pipe is filled with pathogen collection and preservation liquid.

[0006] The innovations of the present invention are: first, a spiral coil designed with micropores is used to release the gas exhaled by the sampled person in a large amount and dispersedly in the solution, so that the pathogens carried in the gas are eluted in a concentrated manner in the pathogen collection and preservation solution; second, the gas exhaled by the sampled person is introduced into the pathogen collection tube by wearing a special mask, and the gas discharged by the mask is all exhaled from the lungs of the sampled person, which contains a large amount of pathogens; third, the sampled person has a good medical compliance with wearing a mask, so the sampled person can wear the mask for a longer time and elute the pathogens, thereby increasing the amount of pathogens collected.

[0007] Furthermore, the body of the collection tube is a 50 ml conical bottom or round bottom centrifuge tube commonly used in laboratories, and the tube cover is modified to use a conventional centrifuge tube, which can be conveniently matched with other related instruments and equipment in subsequent experiments.

[0008] Furthermore, the lower part of the diffuser coil is spirally coiled, and the tube wall of the lower part of the diffuser coil is densely covered with diffuser holes. When the exhaled gas of the subject is discharged from the diffuser coil, it is fully contacted and mixed with the pathogen collection and preservation solution through the numerous and tiny diffuser holes, so that the pathogenic microorganisms in the exhaled gas are fully dissolved in the pathogen collection and preservation solution.

[0009] Furthermore, the aperture of the air diffusion hole is 0.1-0.3 mm. The smaller the aperture, the smaller the bubble of the exhaled gas, and relatively speaking, the larger the surface area of ​​the bubble, the larger the area in contact with the pathogen collection and preservation solution, and the more opportunities for the bubble to dissolve in the pathogen preservation solution. In addition, the design of the small aperture allows more air diffusion holes to be set on the limited spiral coil.

[0010] Furthermore, it also includes a cold storage box, which includes a hollow box body, a slot, a belt and a water inlet. The top of the box body is provided with a slot for placing a collection tube, so that the collection tube can be snugly placed in the cold storage box; the box body is provided with a belt, which is convenient for the sampled person to hang it comfortably on the body for long-term sampling; the water inlet is provided on the upper surface of the box body, and water or other refrigerants can be injected into the cold box through the water inlet, so that when the cold storage box is pre-cooled, the pathogenic microorganisms dissolved in the collection box can better preserve their biological activity at low temperature.

[0011] Furthermore, a check valve is also included. The air inlet end of the diffuser coil is provided with a check valve to prevent the storage liquid in the collection pipe from flowing back into the gas transmission pipe.

[0012] Furthermore, the exhaust pipe is provided with a filter membrane and a waterproof breathable membrane, which can filter the gas discharged from the collection pipe while ensuring that the preservation liquid in the collection pipe will not spray out, thereby preventing pathogens from escaping and causing environmental pollution.

[0013] The advantages of the present invention are: the present invention uses a mask to collect pathogens exhaled from the lungs of the sampled person, and then uses a pathogen collection and preservation solution to elute the exhaled gas, so that the pathogens entrained in the exhaled gas are eluted into the pathogen collection and preservation solution, thereby achieving the purpose of conveniently and massively collecting pathogens of lower respiratory tract infections. The device has the advantages of simple structure, convenient use, good medical compliance, ability to collect pathogenic microorganisms of lower respiratory tract infections, large enrichment and collection volume, and ability to maintain the biological activity of pathogens; it has a simple structure, and each component can be flexibly disassembled, convenient for transportation and use, low manufacturing cost, strong practicality, and is suitable for collecting pathogens of various respiratory infectious diseases. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 It is a structural schematic diagram of a mask-type respiratory pathogen sampling device of the present invention;

[0015] Figure 2 The present invention is a schematic structural diagram of a tube cover and a diffuser coil in a mask-type respiratory pathogen sampling device. DETAILED DESCRIPTION

[0016] The present invention is described in detail below with reference to the accompanying drawings:

[0017] In the description of the present invention, it should be noted that the directions or positional relationships indicated by "left", "right", "up" and "down" are based on the directions or positional relationships shown in the accompanying drawings, or are the directions or positional relationships in which the product of the invention is usually placed when in use. They are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore cannot be understood as a limitation on the present invention.

[0018] like Figure 1-2 As shown, a mask-type respiratory pathogen sampling device includes a mask 1, an air supply pipe 2, a collection pipe 3, a pipe cover 4, a diffuser coil 5, an exhaust pipe 6, a diffuser hole 7, a cold storage box 8 and a check valve 9. The mask 1 is provided with a one-way valve air inlet 11 and an air outlet 12, and the collection pipe 3 is detachably provided with a pipe cover 4. The collection pipe 3 adopts a 50ml universal conical bottom or round bottom centrifuge tube, and a pathogen collection and preservation liquid is arranged inside the tube. One of the innovative points of this embodiment is that the 50ml centrifuge tube commonly used in the laboratory is used for transformation, and only the diffuser coil 5 and the exhaust pipe 6 need to be inserted and arranged on the pipe cover 4. Before use, the pipe openings of the diffuser coil 5 and the exhaust pipe 6 will be covered with a rubber cover to prevent the pre-installed pathogen collection and preservation liquid from being contaminated or leaking. After the various components of the collection pipe are assembled, the diffuser coil 5 extends to the lower part of the collection pipe 3, and a filter membrane and a waterproof breathable membrane are arranged at the pipe opening of the exhaust pipe 6, and the filter membrane is located on the outside. One end of the gas pipe 2 is inserted into the gas outlet 12, and the other end of the gas pipe 2 is inserted into the diffuser coil 5. The diffuser coil 5 is provided with a check valve 9 at the end connected to the gas pipe 2 to prevent the preservation liquid from flowing back into the gas pipe 2.

[0019] The end of the diffuser coil 5 of this embodiment is closed, and it is composed of a straight tube and a spiral coil. The spiral coil is located at the lower part of the diffuser coil 5, and the straight tube passes through the middle of the spiral coil. The upper end of the straight tube protrudes from the tube cover 4, and the lower end is connected to the bottom of the spiral coil. Diffusion holes 7 are arranged on the lower half of the spiral coil and the straight tube. The diffusion holes 7 are orderly and densely distributed thereon, and the aperture of the diffusion holes 7 is 0.2mm. The refrigeration box 8 includes a hollow box body 81, a slot 82, a belt 83 and a water injection port 84. The upper part of the box body 81 is provided with a slot 82 for placing the collection tube 3; the box body 81 is provided with a belt 83; and the water injection port 84 is arranged on the upper surface of the box body 81. When the user needs to wear it for a long time to collect pathogens, the pre-cooled refrigeration box 8 can be taken out of the refrigerator, hung on the body, and then the collection tube 3 is plugged in, and the gas supply pipe 2 is connected.

[0020] Although the specific embodiments of the present invention have been described and illustrated in detail above, it should be noted that various changes and modifications may be made to the above embodiments without departing from the spirit of the present invention and the scope of the appended claims.

Claims

1. A mask-type respiratory pathogen sampling device, characterized in that: The invention comprises a mask (1), an air supply pipe (2), a collecting pipe (3), a pipe cover (4), a diffuser coil (5) and an exhaust pipe (6); the mask (1) is provided with a one-way valve air inlet (11) and an air outlet (12); the collecting pipe (3) is detachably provided with a pipe cover (4); the diffuser coil (5) and the exhaust pipe (6) are inserted on the pipe cover (4); the diffuser coil (5) extends to the bottom of the collecting pipe (3); one end of the air supply pipe (2) is connected to the air outlet (12) on the mask, and the other end of the air supply pipe (2) is connected to the pipe opening of the diffuser coil (5); the collecting pipe (3) is filled with pathogen collection and preservation liquid. The lower part of the diffuser coil (5) is spirally coiled, and diffuser holes (7) are distributed around the wall of the coil; The exhaust pipe (6) is provided with a filter membrane and a waterproof breathable membrane.

2. A mask-type respiratory pathogen sampling device according to claim 1, characterized in that: The collecting tube (3) is a commonly used centrifuge tube with a pointed bottom or a round bottom.

3. A mask-type respiratory pathogen sampling device according to claim 2, characterized in that: The diameter of the air diffusion holes (7) is 0.1-0.3 mm.

4. A mask-type respiratory pathogen sampling device according to claim 3, characterized in that: The invention also comprises a cold storage box (8), wherein the cold storage box (8) comprises a hollow box body (81), a slot (82), a belt (83) and a water injection port (84), wherein the upper surface of the box body (81) is provided with a slot (82) for accommodating the collection tube (3); the slot (82) is matched with the collection tube (3); the box body (81) is provided with a belt (83); and the water injection port (84) is provided on the upper surface of the box body (81).

5. A mask-type respiratory pathogen sampling device according to claim 4, characterized in that: It also comprises a check valve (9), and the air inlet end of the diffuser coil (5) is provided with a check valve (9).

Citation Information

Patent Citations

  • Metal mask convenient for gas sampling

    CN107132085A

  • Breathing mask

    CN111228623A

  • Mask type respiratory pathogen sampling device

    CN212438678U

  • Virus collector

    JP2008119552A

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