Biological tissue sampling device
By designing a high-fidelity fast material extraction device including a cylinder, a cutting part and an operating part, the problems of interference and irregularity in the process of biological tissue extraction are solved, the high-fidelity and standardization of biological tissue extraction are achieved, and the accuracy of pathological identification is improved.
Patent Information
- Application Number
- CN202411683083.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-22
- Publication Date
- 2025-02-28
AI Technical Summary
During the process of obtaining biological tissue materials, due to mutual interference between different biological tissues, the structure, state and biological characteristics of biological tissue are difficult to maintain, which in turn affects the accuracy of pathological identification. At the same time, irregular operation leads to inconsistent cutting size.
A high-fidelity fast material extraction device is provided, including a cylinder, a cutting part and an operating part, through which biological tissue is cut under a specific force through the cutting part of the cylinder, and the standardization and fidelity of material extraction are ensured through the scale and barrier layer.
It effectively reduces interference when taking materials from different biological tissues, improves the high fidelity and standardization of biological tissues, reduces pathogen transmission, and improves the accuracy of pathological identification.
Smart Images

Figure CN119529993A_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of biological material collection, in particular to a biological tissue collection device. Background Art
[0002] Pathological identification is a way to provide important evidence. It identifies biological tissues through autopsy and other methods, analyzes the true cause of death, and thus provides a more accurate scientific basis for effective judgments on various cases. Pathological sampling is a key step in pathological identification, and the quality of the sample plays a vital role in the subsequent determination of the cause of death. However, when sampling from different biological tissues, due to mutual interference between different biological tissues and other reasons, it is difficult to effectively maintain the structure, state, and biological characteristics of the biological tissues, which causes a large error between the subsequent pathological identification and the actual situation. At the same time, the operator cuts the biological tissue based on experience, which leads to inconsistent and non-standard cutting sizes when sampling from different biological tissues.
[0003] Therefore, how to reduce the interference when sampling different biological tissues and improve the high fidelity when sampling different biological tissues, and at the same time, improve the standardization and normativeness of biological tissue sampling have become technical problems that technical personnel in this field urgently need to solve. Summary of the invention
[0004] The purpose of the present invention is to provide a biological tissue sampling device to reduce interference when sampling different biological tissues, improve the high fidelity when sampling different biological tissues, and at the same time, improve the standardization and normativity of biological tissue sampling.
[0005] To achieve the above object, the present invention provides the following solutions:
[0006] The present invention provides a high-fidelity rapid sampling device for a high-level biosafety dissection room, the high-fidelity rapid sampling device comprising:
[0007] A barrel, wherein the barrel has a cavity for storing biological tissue, an entrance communicating with the cavity is provided at the first end of the barrel, graduation lines are provided outside the barrel, and the graduation lines are arranged along the axial direction of the barrel, a first cutting portion is provided at the first end of the barrel, and a channel for the first cutting portion to enter the cavity is provided on the barrel, and the channel is communicated with the cavity;
[0008] The first cutting portion has a cutting state and an idle state. When the first cutting portion is in the cutting state, the first cutting portion enters the cavity through the channel under a first force and moves in the cavity along a first direction, thereby applying a second force to the connection between the biological tissue in the cavity and the biological tissue outside the cavity. The second force causes the biological tissue entering the cavity to be disconnected from the biological tissue outside the barrel. When the first cutting portion is in the idle state, the first cutting portion is located outside the cavity.
[0009] Wherein, the first direction and the axial direction of the cylinder are arranged obliquely or perpendicularly;
[0010] An operating part is connected to the barrel, the operating part is arranged to avoid the entrance, a barrier layer is arranged between the operating part and the barrel, the barrier layer is used to isolate pathogens, and the operating part, the barrier layer and the second end of the barrel are all detachably connected.
[0011] Preferably, there is line contact between the first cutting portion and the biological tissue.
[0012] Preferably, a support portion is provided on the cylinder, the support portion is located between the two ends of the cylinder, and the support portion is communicated with the channel; and the cutting wire includes an annular cutting portion.
[0013] Preferably, the first direction is the radial direction of the cylinder.
[0014] Preferably, the high-fidelity rapid sampling device further comprises a second cutting portion, which is disposed at the first end of the cylinder, is arranged along the circumference of the cylinder, and faces a side away from the cylinder.
[0015] Preferably, the operating part comprises a first push-pull rod, a push-pull plate is provided at the first end of the first push-pull rod, the push-pull plate extends into the cavity, the push-pull plate can move axially along the cylinder, and the barrier layer is provided on the side of the push-pull plate facing the inlet.
[0016] Preferably, a pressure relief hole is provided on the cylinder.
[0017] Preferably, the first acting force is a torsional force exerted by the barrel on the biological tissue when the barrel is rotated. At this time, the barrel constitutes the first cutting portion.
[0018] Preferably, the inner wall of the cavity is covered with a first isolation membrane, and the first isolation membrane is detachably connected to the cavity.
[0019] Compared with the prior art, the present invention has achieved the following technical effects:
[0020] The high-fidelity rapid sampling device of the present invention comprises a barrel, a cavity is provided in the barrel, an entrance connected to the cavity is provided at the first end of the barrel, a first cutting part is provided at the first end of the barrel, a channel for the first cutting part to enter the cavity is provided on the barrel, the channel is connected to the cavity, and the first direction is inclined or perpendicular to the axial direction of the barrel; when biological tissue sampling is required, the first end of the barrel is aimed at the biological tissue, and the barrel is pressed into the biological tissue, and after the biological tissue entering the barrel reaches the required length, the first cutting part enters the cavity through the channel under the first force applied by the operator or mechanical equipment, and moves in the cavity along the first direction, so as to apply a second force to the connection between the biological tissue in the cavity and the biological tissue outside the cavity, separate the biological tissue entering the cavity from the biological tissue outside the barrel, and then put the biological tissue in the barrel into a sealing bag or a storage bag, so as to complete the sampling of the biological tissue;
[0021] Among them, a barrier layer is provided between the operating part and the barrel, so that when the high-fidelity rapid sampling device of the present invention is sampling biological tissue, pathogens and other substances on the biological tissue will not adhere to the operating part, thereby avoiding the problem that pathogens and other substances attached to the operating part adhere to the next biological tissue entering the cavity, causing errors in the pathological identification of the next biological tissue. In addition, the operating part and the barrel, and the operating part and the barrier layer are all detachably connected, so that when the present invention is sampling different types of biological tissues, different barrels and barrier layers can be replaced to prevent pathogens and other impurities of the previous biological tissue attached to the barrel and / or the barrier layer from adhering to the next biological tissue, causing errors in the subsequent identification and analysis of the next biological tissue, thereby improving the accuracy of pathological identification after sampling from different biological tissues, that is, achieving high fidelity when sampling from different biological tissues;
[0022] Furthermore, scale lines are provided along the axial direction of the cylinder. By observing the scale lines, the operator can clearly understand the depth of the cylinder inserted into the large volume of biological tissue, that is, the length of the biological tissue entering the cavity. This makes it possible to obtain biological tissue of the required length when using the high-fidelity rapid sampling device in the present invention, making the sampling of biological tissue more standardized and normalized. BRIEF DESCRIPTION OF THE DRAWINGS
[0023] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.
[0024] Figure 1 This is a schematic diagram of the structure of a high-fidelity rapid material acquisition device;
[0025] Figure 2 This is the internal schematic diagram of the high-fidelity rapid material acquisition device;
[0026] Figure 3 It is a side view schematic diagram of a high-fidelity rapid material acquisition device;
[0027] Figure 4 It is a structural schematic diagram of the support part;
[0028] Figure 5 is a schematic structural diagram of a first pull hook;
[0029] Figure 6 is a schematic structural diagram of a second draw hook;
[0030] Figure 7 is a schematic diagram of the structure of the channel;
[0031] Among them, 1. the second cutting part; 2. the cylinder; 3. the first push-pull rod; 4. the second push-pull rod; 5. the supporting part; 6. the push-pull plate; 7. the pressure relief hole; 8. the first pull hook; 9. the second pull hook; 10. the cutting wire; 11. the channel; 12. the scale line. DETAILED DESCRIPTION
[0032] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0033] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the present invention is further described in detail below with reference to the accompanying drawings and specific embodiments.
[0034] like Figure 1 to Figure 7As shown, the present invention discloses a high-fidelity rapid sampling device for a high-level biosafety dissection room, the high-fidelity rapid sampling device comprising: a barrel 2, the barrel 2 having a cavity for storing biological tissue, a first end of the barrel 2 being provided with an entrance connected to the cavity, a scale line 12 being provided outside the barrel, the scale line 12 being arranged along the axial direction of the barrel 2, a first cutting portion for cutting biological tissue being provided at the first end of the barrel 2, a channel 11 for the first cutting portion to enter the cavity being provided on the barrel 2, the channel 11 being connected to the cavity, the first cutting portion having a cutting state and an idle state, when the first cutting portion is in the cutting state, the first cutting portion is under a first force Entering the cavity through the channel 11, the first cutting part applies a second force to the connection between the biological tissue in the cavity and the biological tissue outside the cavity, and the second force disconnects the biological tissue entering the cavity from the biological tissue outside the cylinder 2; when the first cutting part is in an idle state, the first cutting part is located outside the cavity, and the movement trajectory of the first cutting part and the biological tissue entering the cavity is avoided; the first direction is inclined or vertically set relative to the axial direction of the cylinder; an operating part, a barrier layer is provided between the operating part and the second end of the cylinder 2, the barrier layer is used to isolate impurities such as pathogens, and the operating part and the barrier layer, the second end of the cylinder 2 are all detachably connected.
[0035] When biological tissue sampling is required, the first end of the barrel 2 is aligned with the biological tissue, and the barrel 2 is pressed into the biological tissue. When the biological tissue entering the barrel 2 reaches the required length, the first cutting portion enters the cavity through the channel 11 under the first force applied by the operator or mechanical equipment, and moves in the cavity along the first direction, thereby applying a second force to the connection between the biological tissue in the cavity and the biological tissue outside the cavity, separating the biological tissue entering the cavity from the biological tissue outside the barrel 2, and then placing the biological tissue in the barrel 2 in a sealing bag or a storage bag, etc., to complete the sampling of the biological tissue;
[0036] Among them, a barrier layer is provided between the operating part and the barrel 2, so that when the high-fidelity rapid sampling device of the present invention is sampling biological tissue, pathogens and other substances on the biological tissue will not adhere to the operating part, thereby avoiding the problem that pathogens and other substances attached to the operating part adhere to the next biological tissue entering the cavity, resulting in errors in the pathological identification of the next biological tissue. In addition, the operating part and the barrel 2, and the operating part and the barrier layer are all detachably connected, so that when the present invention is sampling different types of biological tissues, different barrels 2 and barrier layers can be replaced to prevent pathogens and other substances attached to the barrel 2 and / or the barrier layer. Impurities such as pathogens from the previous biological tissue adhere to the next biological tissue, causing errors in the subsequent identification and analysis of the next biological tissue, thereby improving the accuracy of pathological identification after sampling from different biological tissues, that is, achieving high fidelity when sampling from different biological tissues; furthermore, scale lines are provided along the axial direction of the cylinder 2. By observing the scale lines, the operator can clearly understand the depth of the cylinder 2 inserted into the large volume of biological tissue, that is, the length of the biological tissue entering the cavity, which enables the biological tissue of the required length to be obtained when the high-fidelity rapid sampling device in the present invention is used, making the sampling of biological tissues more standardized and normalized. At the same time, in the process of sampling from different biological tissues, the present invention only needs to replace the barrier layer and the cylinder 2, and there is no need to replace the high-fidelity rapid sampling device as a whole, which reduces the cost of the present invention in the process of sampling from different biological tissues.
[0037] The barrel 2 is used to temporarily store biological tissues during the sampling process. The barrel 2 supports the biological tissues entering the cavity, so that the first cutting part can separate the biological tissues entering the cavity from the biological tissues outside the cavity. In addition, the barrel 2 also isolates the biological tissues entering the cavity from the external environment, especially the operator, to avoid the damage of the biological tissues with more harmful effects such as highly infectious diseases to the external environment and the operator. The barrel 2 can also be set as a visual barrel 2, so that the operator can more clearly observe the length and state of the biological tissues entering the cavity.
[0038] The first cutting portion is arranged to avoid the movement trajectory of the biological tissue entering the cylinder 2, which means that the first cutting portion can smoothly separate the biological tissue entering the cavity from the biological tissue outside the cavity, and will not hinder the biological tissue from entering the cavity or damage the biological tissue.
[0039] The first cutting portion and the biological tissue can be in line contact or surface contact; compared with surface contact, when the first cutting portion and the biological tissue are in line contact, the contact area between the first cutting portion and the biological tissue is smaller, and the first cutting force is mainly concentrated near the "cutting line" of the first cutting portion (the cutting line can be understood as the linear cutting edge of the first cutting portion), and no additional lateral force is applied to the biological tissue around the first cutting portion, thereby reducing damage to the biological tissue, effectively maintaining the morphological structure of the biological tissue, and further improving the fidelity when sampling from different biological tissues.
[0040] When the first cutting part and the biological tissue are in line contact, the first cutting part may specifically include a cutting wire 10 such as a metal wire that has the ability to cut biological tissue and can achieve a line contact with the biological tissue. The cutting wire 10 has sufficient strength to complete the cutting of the biological tissue.
[0041] The setting of the channel 11 must not significantly reduce the strength of the barrel 2, ensuring that the barrel 2 can be smoothly inserted into and pulled out of the biological tissue, and the setting of the channel 11 must also ensure that the cutting wire 10 can achieve complete cutting of the cross section of the biological tissue, so as to ensure that the cut biological tissue is of the required length. The cutting wire 10 can be specifically linear. When the biological tissue entering the cavity reaches a preset length, the cutting wire 10 is inserted from the channel 11 on one side of the barrel 2, and then extended from the other side opposite to the barrel 2, thereby completing the partial cutting of the cross section of the connection between the biological tissue in the cavity and the biological tissue outside the cavity, and then the cutting wire 10 is moved in the cavity until the connection between the biological tissue in the cavity and the biological tissue outside the cavity is completely disconnected; at this time, the first force can be applied by the operator, and the directions of the first force and the second force are the same.
[0042] Alternatively, the cutting wire 10 may not be linear. Figure 3 , Figure 4 As shown, a support portion 5 is provided on the barrel 2, and the support portion 5 is located between the two ends of the barrel 2, and the support portion 5 is connected to the channel 11, and the cutting wire 10 includes a ring-shaped cutting portion. The support portion 5 can be made of either a rigid material or an elastic material; when the support portion 5 is an elastic support portion, after the biological tissue entering the cavity reaches the required length, when the cutting wire 10 is retracted inward, the support portion 5 will be deformed so that the cutting wire 10 completely cuts off the connection between the biological tissue in the cavity and the biological tissue outside the cavity. After the cutting is completed, the support portion 5 can restore its original shape under the action of its own elastic force. The first cutting portion can be sleeved on the support portion 5 before the biological tissue enters the cavity, or it can be sleeved on the support portion 5 after the biological tissue enters the cavity. When the biological tissue enters the cavity, the operator squeezes and retracts the first cutting portion inward until the first cutting portion completes the cutting of the connection between the biological tissue in the cavity and the biological tissue outside the cavity.
[0043] Among them, the first cutting part can be a cutting wire 10 with a certain elasticity. For example, the first end of the cutting wire 10 is bent or welded to form a first ring, and the other areas of the cutting wire 10 are inserted into the first ring, and the cutting wire 10 forms a second ring, which means that the areas of the cutting wire 10 other than the first ring are slidably connected to the first ring. At the same time, for this reason, the size of the second ring can be adjusted by sliding the first ring in the areas of the cutting wire 10 other than the first ring; at this time, the second ring is sleeved outside the support part 5, and when the biological tissue enters the cavity to the required length, the second ring is retracted inward until the cutting wire 10 completes the cutting of the connection between the biological tissue in the cavity and the biological tissue outside the cavity. Furthermore, the second end of the cutting wire 10 can be directly pulled by the operator, and at this time, the directions of the first force and the second force are perpendicular to each other, or, as Figure 6 , Figure 7 As shown, when the operating part is set along the direction of the biological tissue entering the cavity, the second end of the cutting wire 10 can also be connected to the second hook 9 on the second push-pull rod 4 of the operating part. By pulling the second push-pull rod 4 in the direction away from the entrance, the cutting wire 10 moves in the channel 11 and shrinks toward the inside of the cavity, thereby completing the cutting of the connection between the biological tissue inside the cavity and the biological tissue outside the cavity.
[0044] Alternatively, the first cutting portion may not adopt the above-mentioned form. For example, the first acting force includes the torsional force applied by the cylinder 2 to the biological tissue when the cylinder 2 is rotated, and the torsional force generated by the rotation of the cylinder 2 is large enough to smoothly disconnect the biological tissue in the cavity from the biological tissue outside the cavity. At this time, the cylinder 2 is equivalent to the first cutting portion. When the biological tissue in the cavity and the biological tissue outside the cavity are disconnected by the torsional force applied to the biological tissue by the rotation of the cylinder 2, it is necessary to ensure that the torsional force generated by the rotation of the cylinder 2 can be effectively transmitted to the biological tissue. To achieve the above-mentioned effect, there is an interference fit between the cavity and the biological tissue entering the cavity, or there is no interference fit between the cavity and the biological tissue entering the cavity, but there is a sufficiently large friction between the cavity and the biological tissue entering the cavity; or the connection between the biological tissue in the cavity and the biological tissue outside the cavity is clamped by a clamping mechanism; or other matching methods or structures that can meet the condition that the torsional force generated by the rotation of the cylinder 2 can be effectively transmitted to the biological tissue. At this time, the first force includes the torsional force exerted by the cylinder 2 on the biological tissue, the friction between the cylinder 2 and the biological tissue, and the clamping force applied to the biological tissue by the clamping mechanism (if the working conditions require, the clamping mechanism can be omitted to ensure that the friction between the cylinder 2 and the biological tissue is large enough).
[0045] The operating part can be a handheld part for the operator to collect biological tissue samples. According to the needs, the operating part can be set as a solid structure or a hollow structure. And by setting the operating part, the body temperature of the operator will not be directly transmitted to the biological tissue through the barrel 2, which reduces the damage of the operator's body temperature to the structure and morphology of the biological tissue, and ensures the accuracy of pathological identification after the biological tissue is collected. The barrier layer has a variety of settings. Specifically: when the cavity is connected to the operating part, the barrier layer is arranged on the side of the cavity facing the barrier layer and / or the side of the operating part facing the cavity. The barrier layer can be a structure such as an isolation film or an isolation plate that can reduce or even isolate pathogens and other impurities in the cavity and prevent pathogens and other impurities from being contaminated on the operating part; when the cavity is not connected to the operating part, the barrel 2 and the shell of the operating part are equivalent to the barrier layer. The operating part can be arranged along the axial direction of the barrel 2, or it can be arranged not along the axial direction of the barrel 2, for example, it is connected to the side of the barrel 2. The specific setting method depends on the working conditions.
[0046] like Figure 1 , Figure 2 , Figure 3 As shown, the high-fidelity rapid sampling device of the present invention further includes a second cutting part 1, which is arranged at the first end of the barrel 2, and the second cutting part 1 is arranged along the circumference of the barrel 2, and the area of the second cutting part 1 with cutting ability faces the side away from the barrel 2. With such arrangement, when the high-fidelity rapid sampling device of the present invention is used to sample biological tissue, the barrel 2 is pressed into the biological tissue, and the biological tissue is entered under the combined action of the pressing force and the cutting force of the second cutting part 1, so that part of the biological tissue enters the cavity; obviously, with the assistance of the second cutting part 1, the process of part of the biological tissue entering the cavity is smoother, the sampling of biological tissue is smoother, and the time of sampling biological tissue is shorter. In addition, this avoids the problem that part of the biological tissue is entangled and damaged by the barrel 2, which reduces the fidelity of subsequent biological tissue sampling, because there is no cutting structure at the first end of the barrel 2, and part of the biological tissue enters the cavity only by pressing.
[0047] However, it should be understood that the second cutting portion 1 is not a necessary structure. When the strength of the cylinder 2 is sufficient, the force pressing the cylinder 2 into the biological tissue is sufficient, and the biological tissue will not be significantly damaged, the second cutting portion 1 is not provided, and the cylinder 2 can be directly pressed into the biological tissue to allow part of the biological tissue to enter the cavity.
[0048] like Figure 1 , Figure 2As shown, the operating part includes a first push-pull rod 3, a push-pull plate 6 is provided at the first end of the first push-pull rod 3, and the other end of the first push-pull rod 3 is an operating end. The push-pull plate 6 extends into the cavity, and the push-pull plate 6 can move along the axial direction of the cylinder 2. The barrier layer is arranged on the side of the push-pull plate 6 facing the entrance; in this way, when the biological tissue enters the cavity to the required length, the first cutting part is used to complete the cutting of the connection between the biological tissue in the cavity and the biological tissue outside the cavity. Subsequently, the operator pushes the biological tissue in the cavity out of the cavity by moving the first push-pull rod 3 in the direction close to the entrance, and places it in a sealing bag or a storage bag or other device. At this time, after completing a biological tissue sampling, the barrier layer needs to be replaced to prevent pathogens and other impurities on the barrier layer from contaminating the next biological tissue to be sampled; if the barrier layer is integrally arranged with the first push-pull rod 3, the first push-pull rod 3 is replaced together.
[0049] like Figure 2 , Figure 5 As shown, the barrier layer can be specifically a second isolation membrane, which can be directly sleeved on the push-pull plate 6, or, in addition to being sleeved on the push-pull plate 6, both ends of the second isolation membrane can also be hung on the first hooks 8 arranged along the circumference of the operating part.
[0050] As with 1, Figure 2 As shown, a pressure relief hole 7 is provided on the cylinder 2, and the pressure relief hole 7 allows the air in the cavity to be discharged in time when the biological tissue enters the cavity, thereby ensuring the smoothness of the biological tissue entering the cavity.
[0051] In the present invention, the inner wall of the cavity is covered with a first isolation membrane, and the first isolation membrane is detachably connected to the cavity, for example, by bolt connection, clamping, etc.; the first isolation membrane isolates the biological tissue from the cavity, preventing pathogens and other impurities on the biological tissue from being contaminated by the cavity, so that after the high-fidelity rapid sampling device in the present invention completes a biological tissue sampling, the first isolation membrane can be directly removed and replaced, thereby preventing pathogens and other impurities contaminated in the cavity from adhering to the next biological tissue to be sampled, thereby ensuring the fidelity when sampling different biological tissues.
[0052] It should be noted that the "high-level organisms" in the high-fidelity rapid sampling device for a high-level biosafety dissection room of the present invention means that the sampling device of the present invention can sample biological tissues of monkeys and humans; "safety" means that during the biological tissue sampling process, the biological tissue in the cavity is fixed in the cylinder 2, and there is no direct contact between the biological tissue and the operator, so the biological tissue sampling process is relatively safe; "dissection room" means that the sampling device of the present invention can be used to sample biological tissues in the dissection room; "high fidelity" means that the present invention arranges the operating part, the cylinder 2 and the isolation layer to be detachably connected, so as to avoid the pathogens on the previous biological tissue from adhering to the cylinder 2, the isolation layer and the operating part, and the pathogens attached to the next The problem of reducing the accuracy of the next biological tissue identification on the biological tissue to be sampled is solved. Moreover, if the working conditions require, for example, a higher degree of fidelity in the sampling of biological tissue is required, then in addition to the detachable connection between the operating part and the barrel 2 and the isolation layer, "high fidelity" also includes direct line contact between the first cutting part and the biological tissue located in the cavity, that is, the first cutting part completes the disconnection of the biological tissue in the cavity and the biological tissue outside the cavity by line cutting; "fast" means that the setting of the second cutting part 1 makes the biological tissue enter the barrel 2 at a faster rate, and the sampling device of the present invention can achieve high-fidelity sampling of biological tissue, without the need for additional arrangement of other equipment, and the sampling steps are relatively simple.
[0053] And / or means that the text content located in front of and / or and the text content located in the back of and / or can exist at the same time or separately; for example, A and / or B includes three situations: A and B exist at the same time, and A or B exists alone.
[0054] The present invention discloses multiple technical solutions, but does not provide any contrary technical inspiration.
[0055] The present invention uses specific examples to illustrate the principles and implementation methods of the present invention. The above examples are only used to help understand the method and core ideas of the present invention. At the same time, for those skilled in the art, according to the ideas of the present invention, there will be changes in the specific implementation methods and application scope. In summary, the content of this specification should not be understood as limiting the present invention.
Claims
1. A high-fidelity rapid sampling device for a high-level biosafety dissection room, characterized in that: The high-fidelity rapid material acquisition device comprises: A barrel, wherein the barrel has a cavity for storing biological tissue, an entrance communicating with the cavity is provided at the first end of the barrel, graduation lines are provided outside the barrel, and the graduation lines are arranged along the axial direction of the barrel, a first cutting portion is provided at the first end of the barrel, and a channel for the first cutting portion to enter the cavity is provided on the barrel, and the channel is communicated with the cavity; The first cutting portion has a cutting state and an idle state. When the first cutting portion is in the cutting state, the first cutting portion enters the cavity through the channel under a first force and moves in the cavity along a first direction, thereby applying a second force to the connection between the biological tissue in the cavity and the biological tissue outside the cavity. The second force causes the biological tissue entering the cavity to be disconnected from the biological tissue outside the barrel. When the first cutting portion is in the idle state, the first cutting portion is located outside the cavity. Wherein, the first direction is arranged obliquely or perpendicularly to the axial direction of the cylinder; An operating part is connected to the barrel, the operating part is arranged to avoid the entrance, a barrier layer is arranged between the operating part and the barrel, the barrier layer is used to isolate pathogens, and the operating part, the barrier layer and the second end of the barrel are all detachably connected.
2. The high-fidelity rapid material acquisition device according to claim 1, characterized in that: The first cutting portion is in line contact with the biological tissue.
3. The high-fidelity rapid material acquisition device according to claim 2, characterized in that: The cylinder is provided with a support portion, the support portion is located between the two ends of the cylinder, and the support portion is communicated with the channel; the cutting wire includes an annular cutting portion.
4. The high-fidelity rapid material acquisition device according to claim 1, characterized in that: The first direction is the radial direction of the cylinder.
5. The high-fidelity rapid material acquisition device according to claim 1, characterized in that: The high-fidelity rapid sampling device further comprises a second cutting portion, which is disposed at the first end of the cylinder, is arranged along the circumference of the cylinder, and faces a side away from the cylinder.
6. The high-fidelity rapid material acquisition device according to claim 1, characterized in that: The operating part includes a first push-pull rod, a push-pull plate is provided at the first end of the first push-pull rod, the push-pull plate extends into the cavity, the push-pull plate can move along the axial direction of the cylinder, and the barrier layer is provided on the side of the push-pull plate facing the inlet.
7. The high-fidelity rapid material acquisition device according to claim 1, characterized in that: The cylinder is provided with a pressure relief hole.
8. The high-fidelity rapid material acquisition device according to claim 1, characterized in that: The inner walls of the cavity are covered with a first isolation membrane, and the first isolation membrane is detachably connected to the cavity.
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