Cracking structure and tissue dissociation equipment

Abstract

The utility model relates to the technical field of tissue dissociation equipment, and discloses a splitting structure and tissue dissociation equipment, the splitting structure comprises a splitting assembly, the splitting assembly is of a hollow structure, a plurality of splitting knives which are arranged in a circumferential mode are installed on the splitting assembly, the splitting knives are inclined, and a plurality of connecting parts which are arranged in a circumferential mode and used for installation are arranged on the splitting assembly. An inserting groove and an inserting cavity are formed in the connecting part, an inserting rod is arranged on the cracking knife, an extension rod fixed to the inserting cavity is arranged in the inserting rod, an adjusting part used for adjusting the position of the inserting cavity is arranged in the inserting rod, a transmission rod and a lead screw are arranged in the adjusting part, and a rotating part for driving the transmission rod to rotate is arranged in the cracking assembly. According to the splitting cutter disclosed by the utility model, through the arrangement of the connecting part, the adjusting part and the rotating part, the splitting cutter can be conveniently mounted and dismounted, the splitting cutter can be conveniently overhauled, and the situation that the splitting cutter is damaged, the whole splitting cutter needs to be replaced and waste is caused under an integrated structure is avoided.

Description

Technical Field

[0001] The utility model relates to the technical field of tissue dissociation equipment, in particular to a lysis structure and tissue dissociation equipment. Background Art

[0002] Tissue dissociation generally refers to the separation of antigen-antibody complexes into free antigens and antibodies, and refers to the process in which compounds or molecules release ions in a solvent.

[0003] When the existing cracking structure is in use, the cracking knife thereon is mostly an integrated structure, which cannot be easily installed and disassembled. When the cracking knife is damaged, it needs to be replaced as a whole, which is very inconvenient and wasteful.

[0004] To this end, we propose a lysis structure and tissue dissociation device. Utility Model Content

[0005] The utility model mainly solves the technical problems existing in the above-mentioned prior art and provides a lysis structure and tissue dissociation equipment.

[0006] In order to achieve the above-mentioned purpose, the utility model adopts the following technical scheme: a lysis structure and tissue dissociation equipment, including a lysis component, the lysis component is a hollow structure, a plurality of lysis knives arranged in a circle are installed on the lysis component, the lysis knives are inclined, and a plurality of connecting parts arranged in a circle for installation are opened on the lysis component, the connecting parts include a plug-in groove and a plug-in cavity, a plug-in rod is provided on the lysis knife, an extension rod fixed to the plug-in cavity is provided in the plug-in rod, and an adjustment part for adjusting the position of the plug-in cavity is provided in the plug-in rod, the adjustment part includes a transmission rod and a screw, a rotating part for driving the transmission rod to rotate is provided in the lysis component, and the rotating part includes a rotating shaft, a bevel gear plate and a first bevel gear.

[0007] Furthermore, the plug-in grooves are arranged in a circle on the outer wall of the cracking component, the plug-in cavities are arranged in a circle on the vertical axial inner wall of the plug-in grooves, the plug-in rods are fixedly connected to the two ends and the middle of the outer wall of the cracking knife, and the vertical axial inner wall of the plug-in rods is provided with a plurality of sliding holes arranged in a circle, the extension rod is slidably connected to the inner wall of the sliding hole, and the plug-in rod and the extension rod are respectively adapted to the plug-in groove and the plug-in cavity.

[0008] Furthermore, the top and bottom of the inner wall of the lysis assembly are fixedly connected to a fixed plate, an overflow groove for tissue fluid to pass through is provided on the fixed plate, and the bottom end of the rotating shaft is rotatably connected to the fixed plate at the bottom, and the top of the rotating shaft passes through the fixed plate at the top and is fixedly connected to a knob at the axial position.

[0009] Furthermore, the inner wall of the cracking assembly is provided with three linearly arranged first rotating grooves, the bevel gear plate is rotatably connected to the inner wall of the first rotating groove, and the bevel gear plate is fixedly connected to the outer wall of the rotating shaft and is provided with the same overflow groove.

[0010] Furthermore, a second rotating groove is provided in the plug-in slot, and the second rotating groove extends to the inner wall of the first rotating groove. The first bevel gear is rotatably connected to the inner wall of the second rotating groove and meshes with the outer wall of the bevel gear plate. Limiting holes are provided at both ends of the first bevel gear close to the plug-in slot.

[0011] Furthermore, the bottom end of the transmission rod is rotatably connected to the axial position of the bottom inner wall of the plug-in rod, the top end of the transmission rod passes through the outer wall of the plug-in rod and is fixedly connected to a transmission plate, both ends of the top of the transmission plate are fixedly connected to limit rods that are compatible with the limit holes, and the outer wall of the transmission rod is fixedly connected to a second bevel gear.

[0012] Furthermore, the inner wall of the plug-in rod is fixedly connected to a sliding seat at the axial position of the sliding hole, the extension rod is slidably connected to the inner wall of the sliding seat, the sliding seat is rotatably connected to the third bevel gear meshing with the second bevel gear at the axial position near one end of the transmission rod, and the third bevel gear is fixedly connected to the axial position near one end of the extension rod, the screw rod is rotatably connected to the inner wall of the sliding seat and is threadedly connected to the inner wall of the extension rod.

[0013] Beneficial Effects

[0014] The utility model provides a lysis structure and tissue dissociation equipment, which has the following beneficial effects:

[0015] (1) This lysis structure and tissue dissociation equipment can conveniently install and disassemble the lysis knife through the provided connection part, adjustment part and rotation part, and facilitate the maintenance of the lysis knife, thereby avoiding damage to the lysis knife under the integrated structure, which requires replacement of the entire structure and is very wasteful.

[0016] (2) This lysis structure and tissue dissociation device, through the design of the elongated rod and multiple elongated rods, can bear the stress of the connection along multiple directions when the connection is subjected to external force, thereby improving the pressure-bearing effect of the connection and avoiding loosening of the connection, which affects the stability of the connection.

[0017] (3) The lysis structure and tissue dissociation device, through the lysis knife, are designed to be inclined so that when the tissue block is rotated to lyse, the tissue block can climb and descend along the inclined surface, thereby fully lysing the tissue block and facilitating the full dissociation of the tissue block. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 This is the front view of the utility model;

[0019] Figure 2 It is a cross-sectional view of the utility model;

[0020] Figure 3 For this utility model Figure 2 A magnified view of part A;

[0021] Figure 4 This is a detailed diagram of the cracking knife of the utility model;

[0022] Figure 5 This is a cross-sectional view of the plug-in rod of the utility model.

[0023] Legend: 1. Cracking assembly; 2. Cracking knife; 3. Fixed plate; 4. Knob; 5. Rotating shaft; 6. Bevel gear plate; 7. Plug-in slot; 8. First bevel gear; 9. Limiting hole; 10. Plug-in cavity; 11. Plug-in rod; 12. Transmission rod; 13. Transmission plate; 14. Limiting rod; 15. Second bevel gear; 16. Third bevel gear; 17. Screw; 18. Sliding seat; 19. Extension rod. DETAILED DESCRIPTION

[0024] Embodiment 1: A lysis structure and tissue dissociation device, such as Figure 1 , Figure 2 and Figure 5 As shown, it includes a cracking component 1, which is a hollow structure. A plurality of cracking knives 2 arranged in a circle are installed on the cracking component 1. The cracking knives 2 are inclined, and a plurality of connecting parts arranged in a circle for installation are opened on the cracking component 1, and the connecting part includes a plug-in groove 7 and a plug-in cavity 10. A plug-in rod 11 is provided on the cracking knife 2, and an extension rod 19 fixed to the plug-in cavity 10 is provided in the plug-in rod 11, and an adjusting part for adjusting the position of the plug-in cavity 10 is provided in the plug-in rod 11, and a transmission rod 12 and a screw 17 are included in the adjusting part. A rotating part for driving the transmission rod 12 to rotate is provided in the cracking component 1, and the rotating part includes a rotating shaft 5, a bevel gear plate 6 and a first bevel gear 8.

[0025] By setting the lysis knife 2 and the inclined design of the lysis knife 2, when the tissue block is rotated to lyse, the tissue block can climb and descend along the inclined surface, which fully lyses the tissue block and facilitates the full dissociation of the tissue block.

[0026] like Figure 3 and Figure 5 As shown, the plug-in grooves 7 are arranged in a circle on the outer wall of the cracking component 1, the plug-in cavities 10 are arranged in a circle on the vertical axial inner wall of the plug-in groove 7, the plug-in rod 11 is fixedly connected to the two ends and the middle of the outer wall of the cracking knife 2, and the vertical axial inner wall of the plug-in rod 11 is provided with a plurality of sliding holes arranged in a circle, the extension rod 19 is slidably connected to the inner wall of the sliding hole, and the plug-in rod 11 and the extension rod 19 are respectively adapted to the plug-in groove 7 and the plug-in cavity 10.

[0027] By setting up the extension rod 19 and the design of multiple extension rods 19, when the connection is subjected to external force, the stress of the connection can be subjected to pressure in multiple directions, thereby improving the pressure-bearing effect of the connection and avoiding loosening of the connection to affect the stability of the connection.

[0028] like Figure 2 , Figure 3 As shown, the top and bottom of the inner wall of the lysis assembly 1 are fixedly connected to a fixed plate 3, the fixed plate 3 is provided with an overflow groove for the tissue fluid to pass through, and the bottom end of the rotating shaft 5 is rotatably connected to the fixed plate 3 at the bottom, and the top of the rotating shaft 5 passes through the fixed plate 3 at the top and is fixedly connected to a knob 4 at the axial position.

[0029] The inner wall of the cracking assembly 1 is provided with three linearly arranged first rotating grooves, the bevel gear plate 6 is rotatably connected to the inner wall of the first rotating groove, and the bevel gear plate 6 is fixedly connected to the outer wall of the rotating shaft 5 and provided with the same overflow groove.

[0030] A second rotating groove is provided in the plug-in groove 7 and extends to the inner wall of the first rotating groove. The first bevel gear 8 is rotatably connected to the inner wall of the second rotating groove and meshes with the outer wall of the bevel gear plate 6. Limiting holes 9 are provided at both ends of the first bevel gear 8 close to the plug-in groove 7.

[0031] like Figure 4 and Figure 5 As shown, the bottom end of the transmission rod 12 is rotatably connected to the axial position of the bottom inner wall of the plug-in rod 11, the top end of the transmission rod 12 passes through the outer wall of the plug-in rod 11 and is fixedly connected to a transmission disk 13, both ends of the top of the transmission disk 13 are fixedly connected to limit rods 14 that are compatible with the limit holes 9, and the outer wall of the transmission rod 12 is fixedly connected to a second bevel gear 15.

[0032] The inner wall of the plug-in rod 11 is fixedly connected to a sliding seat 18 at the axial position of the sliding hole, and the extension rod 19 is slidably connected to the inner wall of the sliding seat 18. The sliding seat 18 is rotatably connected to the third bevel gear 16 meshing with the second bevel gear 15 at the axial position close to one end of the transmission rod 12, and the third bevel gear 16 is fixedly connected to the axial position close to one end of the extension rod 19 with a screw rod 17, which is rotatably connected to the inner wall of the sliding seat 18 and threadedly connected to the inner wall of the extension rod 19.

[0033] In summary, through the provided connecting part, adjusting part and rotating part, the cracking knife 2 can be easily installed and disassembled, and the cracking knife 2 can be easily inspected and repaired, thereby avoiding damage to the cracking knife 2 under the integrated structure, which requires replacement of the entire unit and is very wasteful.

[0034] The working principle of the utility model is as follows: when the cracking knife 2 needs to be installed, the connecting rod 11 on the cracking knife 2 is inserted into the plug-in slot 7. At this time, the limiting rod 14 on the side of the transmission disk 13 on the connecting rod 11 can be inserted into the limiting hole 9 on the first bevel gear 8. At this time, the knob 4 is turned, and the knob 4 can drive the first bevel gear 8 meshing thereon to rotate through the rotating shaft 5 and the bevel gear disk 6 thereon. The first bevel gear 8 can drive the transmission disk 13 and the transmission rod 12 to rotate through the limiting rod 14 inserted therein, and the transmission rod 12 drives the third bevel gear 16 meshing thereon to rotate through the second bevel gear 15. The third bevel gear 16 can drive the screw rod 17 to rotate synchronously, and the screw rod 17 can drive the extension rod 19 threadedly connected thereon to slide in the sliding seat 18 and be inserted into the plug-in cavity 10 in the plug-in slot 7 for fixation, and it can be installed. When it needs to be disassembled, it only needs to be rotated in the opposite direction to take the cracking knife 2.

[0035] The above shows and describes the basic principle and main features of the utility model and the advantages of the utility model. Those skilled in the art should understand that the utility model is not limited by the above embodiments. The above embodiments and descriptions are only for explaining the principle of the utility model. Without departing from the spirit and scope of the utility model, the utility model may have various changes and improvements, which fall within the scope of the utility model to be protected. The scope of protection claimed by the utility model is defined by the attached claims and their equivalents.

Claims

1. A cracking structure, comprising a cracking assembly (1), characterized in that: The cracking assembly (1) is a hollow structure. A plurality of cracking knives (2) arranged in a circle are installed on the cracking assembly (1). The cracking knives (2) are inclined. A plurality of connecting parts arranged in a circle for installation are provided on the cracking assembly (1). The connecting parts include a plug-in slot (7) and a plug-in cavity (10). The cracking knives (2) are provided with a plug-in rod (11). The plug-in rod (11) is provided with an extension rod (19) fixed to the plug-in cavity (10). The plug-in rod (11) is provided with an adjustment part for adjusting the position of the plug-in cavity (10). The adjustment part includes a transmission rod (12) and a screw rod (17). The cracking assembly (1) is provided with a rotating part for driving the transmission rod (12) to rotate. The rotating part includes a rotating shaft (5), a bevel gear plate (6) and a first bevel gear (8).

2. The cracking structure according to claim 1, characterized in that: The plug-in grooves (7) are arranged in a circle on the outer wall of the cracking assembly (1); the plug-in cavity (10) is arranged in a circle on the vertical axial inner wall of the plug-in groove (7); the plug-in rod (11) is fixedly connected to the two ends and the middle of the outer wall of the cracking knife (2); the vertical axial inner wall of the plug-in rod (11) is provided with a plurality of sliding holes arranged in a circle; the extension rod (19) is slidably connected to the inner wall of the sliding hole; the plug-in rod (11) and the extension rod (19) are respectively adapted to the plug-in groove (7) and the plug-in cavity (10).

3. The cracking structure according to claim 1, characterized in that: The top and bottom of the inner wall of the lysis assembly (1) are fixedly connected to a fixed plate (3), the fixed plate (3) is provided with an overflow groove for the passage of tissue fluid, and the bottom end of the rotating shaft (5) is rotatably connected to the fixed plate (3) located at the bottom, and the top of the rotating shaft (5) passes through the fixed plate (3) located at the top and is fixedly connected to a knob (4) at an axial position.

4. The cracking structure according to claim 3, characterized in that: The inner wall of the cracking assembly (1) is provided with three first rotating grooves arranged in a linear manner, the bevel gear plate (6) is rotatably connected to the inner wall of the first rotating groove, and the bevel gear plate (6) is fixedly connected to the outer wall of the rotating shaft (5) and is provided with the same overflow groove.

5. The cracking structure according to claim 4, characterized in that: A second rotation groove is provided in the plug-in groove (7), and the second rotation groove extends to the inner wall of the first rotation groove. The first bevel gear (8) is rotatably connected to the inner wall of the second rotation groove and meshes with the outer wall of the bevel gear plate (6). Limiting holes (9) are provided at both ends of the first bevel gear (8) on a side close to the plug-in groove (7).

6. The cracking structure according to claim 1, characterized in that: The bottom end of the transmission rod (12) is rotatably connected to the axial position of the bottom inner wall of the plug rod (11); the top end of the transmission rod (12) passes through the outer wall of the plug rod (11) and is fixedly connected to a transmission disc (13); both ends of the top of the transmission disc (13) are fixedly connected to limit rods (14) that are compatible with the limit holes (9); and the outer wall of the transmission rod (12) is fixedly connected to a second bevel gear (15).

7. The cracking structure according to claim 6, characterized in that: The inner wall of the plug-in rod (11) is fixedly connected to a sliding seat (18) at an axial position of the sliding hole, the extension rod (19) is slidably connected to the inner wall of the sliding seat (18), the sliding seat (18) is rotatably connected to a third bevel gear (16) meshing with the second bevel gear (15) at an axial position close to one end of the transmission rod (12), and the third bevel gear (16) is fixedly connected to a screw rod (17) at an axial position close to one end of the extension rod (19), the screw rod (17) is rotatably connected to the inner wall of the sliding seat (18) and is threadedly connected to the inner wall of the extension rod (19).

8. A tissue dissociation device, characterized in that: The invention comprises the cleavage structure according to any one of claims 1 to 7.

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