Continuous filtering device for tissue extracting solution

Abstract

The utility model relates to the technical field of cell filtering equipment, in particular to a continuous filtering device for tissue extracting solution, which comprises a filtering box, a funnel and a filtering component, the filtering component comprises a filtering plate, a guide plate, a guide pipe, a box body, a water suction pump, a first connecting pipe and a second connecting pipe, and an opening is arranged on the right side surface of the filtering box. A cell culture solution is poured into the filter box from the funnel, then impurities and cell debris in the cell culture solution are filtered through the filter plate, so that the cell culture solution falls from the filter plate, falls onto the guide plate, flows to the guide pipe through the guide plate and then falls into the box body, and meanwhile, the water suction pump is started; the cell culture fluid in the box body enters the filtering box again through the first connecting pipe and the second connecting pipe, so that continuous filtering is performed, the device can perform continuous filtering, workers do not need to manually put the cell culture fluid into the filtering box again, the operation is simple and convenient, and the filtering efficiency is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of cell filtering equipment, in particular to a continuous filtering device for tissue extract. Background Art

[0002] To extract active ingredients, such as exosomes, from cell culture fluid and tissue extract, the cell culture fluid must first be filtered to remove floating cell debris and impurities. Currently, cell debris and impurities are filtered through a filtration device.

[0003] However, the current filtration devices are unable to perform multiple continuous filtrations, resulting in insufficient filtration of impurities in the cell culture fluid. When further filtration is required, the staff is required to put the cell culture fluid back into the filtration device, which is too troublesome and inefficient. Utility Model Content

[0004] The utility model aims to provide a continuous filtering device for tissue extract, which solves the problems in the prior art.

[0005] To achieve the above-mentioned purpose, the utility model provides a continuous filtering device for tissue extract, comprising a filter box, a funnel and a filter assembly, wherein the filter assembly comprises a filter plate, a guide plate, a conduit, a box body, a water pump, a first connecting pipe and a second connecting pipe, the right side of the filter box has an opening, the funnel is connected to the filter box and is located at the top of the filter box, the filter plate is arranged inside the filter box, and the right end of the filter plate is located below the opening, the guide plate is arranged inside the filter box and is located below the filter plate, the box body is fixedly connected to the left side of the filter box, one end of the conduit is connected to the left side of the filter box, and the other end of the conduit is connected to the top of the box body, the water pump is fixedly connected to the left side of the box body, one end of the first connecting pipe is connected to the left side of the box body, and the other end of the first connecting pipe is fixedly connected to the bottom of the water pump, one end of the second connecting pipe is fixedly connected to the top of the water pump, and the other end of the second connecting pipe is connected to the top of the filter box.

[0006] Wherein, the filter assembly further includes a liquid outlet pipe and a first solenoid valve, the liquid outlet pipe is communicated with the box body and is located at the bottom of the box body, and the first solenoid valve is arranged on the liquid outlet pipe.

[0007] Wherein, the filter assembly further includes a guide tube, the guide tube is fixedly connected to the right side surface of the filter box, and the left end of the guide tube is communicated with the opening.

[0008] Wherein, the continuous filtering device for tissue extract further comprises a plurality of supporting legs, one end of each of the plurality of supporting legs is fixedly connected to the filter box respectively and is located around the bottom of the filter box.

[0009] Wherein, the continuous filtering device for tissue extract also includes a collecting tank, which is placed on the ground and located directly below the liquid outlet pipe.

[0010] Among them, the continuous filtration device of the tissue extract also includes a water tank, a first water pipe, a second water pipe, a plurality of nozzles and a second solenoid valve. The water tank is fixedly connected to the filter box and is located at the top of the filter box. One end of the first water pipe is connected to the front surface of the water tank, and the other end of the first water pipe passes through the top of the filter box and is connected to the middle section of the second water pipe. The second water pipe is arranged inside the filter box and is located above the filter plate. The plurality of nozzles are respectively arranged at the lower end of the second water pipe, and the second solenoid valve is arranged on the first water pipe.

[0011] Wherein, the continuous filtering device for tissue extract also includes a box cover, which is rotatably connected to the water tank and is located on the top of the water tank.

[0012] Wherein, the continuous filtering device for tissue extract further comprises a handle, which is fixedly connected to the box cover and is located at the upper end of the box cover.

[0013] Among them, the continuous filtration device for tissue extract also includes two fixed rods, a rotating shaft and a top cover, the two fixed rods are symmetrically arranged at the upper ends of the filter box, the rotating shaft is rotatably connected to the two fixed rods and is located between the two fixed rods, the top cover covers the upper end of the funnel, and the left end of the top cover is fixedly connected to the rotating shaft.

[0014] The utility model discloses a continuous filtering device for tissue extract, wherein the cell culture fluid is poured from the funnel into the filter box, and then the impurities and cell debris in the cell culture fluid are filtered through the filter plate, so that the cell culture fluid falls from the filter plate and falls onto the guide plate, then flows to the conduit through the guide plate, and then falls into the box, and at the same time the water pump is started, so that the cell culture fluid in the box re-enters the filter box through the first connecting pipe and the second connecting pipe, thereby performing continuous filtering, and the impurities and cell debris on the filter plate will flow to the opening and be discharged from the opening to avoid clogging the filter plate, thereby the device can perform continuous filtering, and there is no need for the staff to manually put the cell culture fluid into the filter box again, the operation is simple and convenient, and the filtering efficiency is improved. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art are briefly introduced below.

[0016] Figure 1 It is a schematic diagram of the overall structure of the first embodiment of the utility model.

[0017] Figure 2 It is an overall cross-sectional view of the first embodiment of the utility model.

[0018] Figure 3 It is an overall structural diagram of the second embodiment of the utility model.

[0019] Figure 4 It is an overall cross-sectional view of the second embodiment of the utility model.

[0020] 101-filter box, 102-funnel, 103-support leg, 104-collecting tank, 105-water tank, 106-first water pipe, 107-second water pipe, 108-nozzle, 109-second solenoid valve, 110-box cover, 111-handle, 112-filter plate, 113-guide plate, 114-conduit, 115-box body, 116-water pump, 117-first connecting pipe, 118-second connecting pipe, 119-liquid outlet pipe, 120-first solenoid valve, 121-guide pipe, 122-opening, 201-fixed rod, 202-rotating shaft, 203-top cover. DETAILED DESCRIPTION

[0021] Embodiments of the present invention are described in detail below, and examples of the embodiments are shown in the accompanying drawings. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to be used to explain the present invention, but should not be understood as limiting the present invention.

[0022] First embodiment:

[0023] See also Figure 1 and Figure 2 ,in, Figure 1 It is a schematic diagram of the overall structure of the first embodiment of the utility model. Figure 2 It is an overall cross-sectional view of the first embodiment of the utility model.

[0024] The utility model provides a continuous filtering device for tissue extract, comprising a filter box 101, a funnel 102, a filter assembly, a plurality of support legs 103, a collection tank 104, a water tank 105, a first water pipe 106, a second water pipe 107, a plurality of nozzles 108, a second solenoid valve 109, a box cover 110 and a handle 111, the filter assembly comprises a filter plate 112, a guide plate 113, a conduit 114, a box body 115, a water pump 116, a first connecting pipe 117, a second connecting pipe 118, a liquid outlet pipe 119, a first solenoid valve 120 and a guide pipe 121, and the right side of the filter box 101 has an opening 122.

[0025] According to the present specific embodiment, the cell culture fluid is poured from the funnel 102 into the filter box 101, and then the impurities and cell debris in the cell culture fluid are filtered through the filter plate 112, so that the cell culture fluid falls from the filter plate 112 and falls on the guide plate 113, then flows to the conduit 114 through the guide plate 113, and then falls into the box body 115. At the same time, the water pump 116 is started to make the cell culture fluid in the box body 115 re-enter the filter box 101 through the first connecting pipe 117 and the second connecting pipe 118, so as to perform continuous filtration, and the impurities and cell debris on the filter plate 112 will flow to the opening 122 and be discharged from the opening 122 to avoid clogging the filter plate 112. Thus, the device can perform continuous filtration without the need for the staff to manually put the cell culture fluid back into the filter box 101. The operation is simple and convenient, thereby improving the filtration efficiency.

[0026] The funnel 102 is connected to the filter box 101 and is located at the top of the filter box 101. The filter plate 112 is arranged inside the filter box 101, and the right end of the filter plate 112 is located below the opening 122. The guide plate 113 is arranged inside the filter box 101 and is located below the filter plate 112. The box body 115 is fixedly connected to the left side of the filter box 101. One end of the conduit 114 is fixedly connected to the left side of the filter box 101. The other end of the conduit 114 is connected to the top of the box body 115, the water pump 116 is fixedly connected to the left side of the box body 115, one end of the first connecting pipe 117 is connected to the left side of the box body 115, the other end of the first connecting pipe 117 is fixedly connected to the bottom of the water pump 116, one end of the second connecting pipe 118 is fixedly connected to the top of the water pump 116, and the other end of the second connecting pipe 118 is connected to the top of the filter box 101. The cell culture fluid is poured from the funnel 102 into the filter box 101, and then the impurities and cell debris in the cell culture fluid are filtered through the filter plate 112, so that the cell culture fluid falls from the filter plate 112 and falls on the guide plate 113, then flows to the conduit 114 through the guide plate 113, and then falls into the box 115. At the same time, the water pump 116 is started to make the cell culture fluid in the box 115 re-enter the filter box 101 through the first connecting pipe 117 and the second connecting pipe 118, so as to perform continuous filtration, and the impurities and cell debris on the filter plate 112 will flow to the opening 122 and be discharged from the opening 122 to avoid clogging the filter plate 112. Therefore, the device can perform continuous filtration without the need for the staff to manually put the cell culture fluid into the filter box 101 again, and the operation is simple and convenient, thereby improving the filtration efficiency.

[0027] Secondly, the liquid outlet pipe 119 is connected to the box body 115 and is located at the bottom of the box body 115, and the first solenoid valve 120 is disposed on the liquid outlet pipe 119. When the cell culture fluid is filtered, the water pump 116 is closed, and then the first solenoid valve 120 is opened to discharge the cell culture fluid from the liquid outlet pipe 119.

[0028] At the same time, the guide tube 121 is fixedly connected to the right side of the filter box 101, and the left end of the guide tube 121 is connected to the opening 122. Under the guidance of the guide tube 121, the cell debris and impurities are uniformly dropped to a designated location for storage, preventing the cell debris and impurities from splashing everywhere when falling out of the opening 122, which is inconvenient for later recovery.

[0029] In addition, one end of the plurality of support legs 103 is fixedly connected to the filter box 101, and is located around the bottom of the filter box 101. The collection tank 104 is placed on the ground and is located directly below the liquid outlet pipe 119. The device is supported by the arrangement of the plurality of support legs 103, and the cell culture fluid flowing out of the liquid outlet pipe 119 is collected by the arrangement of the collection tank 104, so that the staff can perform subsequent processing work.

[0030] Finally, the water tank 105 is fixedly connected to the filter box 101 and is located at the top of the filter box 101. One end of the first water pipe 106 is connected to the front surface of the water tank 105. The other end of the first water pipe 106 passes through the top of the filter box 101 and is connected to the middle section of the second water pipe 107. The second water pipe 107 is arranged inside the filter box 101 and is located above the filter plate 112. The plurality of nozzles 108 are respectively arranged at the lower end of the second water pipe 107, and the second solenoid valve 109 is arranged on the first water pipe 106. When the filter box 101 is used for a long time, some impurities will remain inside it, so it needs to be cleaned regularly. First, the second solenoid valve 109 is opened to allow the water in the water tank 105 to flow into the second water pipe 107 through the first water pipe 106, and then the water is sprayed into the filter box 101 through the multiple nozzles 108, so that the water flushes the filter box 101, the filter plate 112, and the guide plate 113. At the same time, the first solenoid valve 120 is opened, and the collection tank 104 is moved away, so that the flushed waste water is discharged from the opening 122 and the liquid outlet pipe 119, so that the device can be cleaned and some cell debris and impurities can be prevented from remaining on the filter plate 112 for a long time and causing the filter plate 112 to be blocked.

[0031] In addition, the box cover 110 is rotatably connected to the water tank 105 and is located at the top of the water tank 105. The handle 111 is fixedly connected to the box cover 110 and is located at the upper end of the box cover 110. When the water in the water tank 105 is insufficient, the staff holds the handle 111 and then pulls it upward, thereby driving the box cover 110 to rotate upward, so as to facilitate pouring external water resources into the water tank 105.

[0032] When using the continuous filtering device for tissue extract of the present embodiment, the cell culture fluid is poured from the funnel 102 into the filter box 101, and then the impurities and cell debris in the cell culture fluid are filtered through the filter plate 112, so that the cell culture fluid falls from the filter plate 112 and falls on the guide plate 113, and then flows to the conduit 114 through the guide plate 113, and then falls into the box 115, and at the same time, the water pump 116 is started to make the cell culture fluid in the box 115 re-enter the filter box 101 through the first connecting pipe 117 and the second connecting pipe 118, so as to perform continuous filtering. The filter plate 112 is filtered, and the impurities and cell debris on the filter plate 112 flow to the opening 122 and are discharged from the opening 122 to avoid clogging the filter plate 112. Thus, the device can perform continuous filtration without the need for the staff to manually put the cell culture fluid into the filter box 101 again. The operation is simple and convenient, thereby improving the filtration efficiency. When the cell culture fluid is filtered, the water pump 116 is closed, and then the first solenoid valve 120 is opened to discharge the cell culture fluid from the outlet pipe 119, so that the cell debris and impurities are guided by the guide pipe 121 and uniformly fall to a designated position for storage, thereby preventing the cell debris and impurities from being filtered. When the liquid falls out of the opening 122, it splashes everywhere, which is not convenient for later recovery. The device is supported by the setting of multiple supporting legs 103, and the cell culture fluid flowing out of the liquid outlet pipe 119 is collected by the setting of the collecting tank 104, which is convenient for the staff to carry out subsequent processing work. When the filter box 101 is used for a long time, some impurities will remain inside it, so it needs to be cleaned regularly. First, the second solenoid valve 109 is opened to allow the water in the water tank 105 to flow into the second water pipe 107 through the first water pipe 106, and then the water is sprayed on the filter box through the multiple nozzles 108. 101, so that the water flow flushes the filter box 101, the filter plate 112, and the guide plate 113. At the same time, the first solenoid valve 120 is opened, and the collecting tank 104 is moved away, so that the flushed waste water is discharged from the opening 122 and the liquid outlet pipe 119, thereby cleaning the device and preventing some cell debris and impurities from remaining on the filter plate 112 for a long time and causing the filter plate 112 to be blocked. When the water in the water tank 105 is insufficient, the staff holds the handle 111 and then pulls it upward, thereby driving the box cover 110 to rotate upward, so as to facilitate pouring external water resources into the water tank 105.

[0033] Second embodiment:

[0034] Based on the first embodiment, please refer to Figure 3 and Figure 4 ,in, Figure 3It is a schematic diagram of the overall structure of the second embodiment of the utility model. Figure 4 It is an overall cross-sectional view of the second embodiment of the utility model.

[0035] The utility model provides a continuous filtering device for tissue extract, which also includes two fixing rods 201 , a rotating shaft 202 and a top cover 203 .

[0036] With respect to this specific embodiment, the top cover 203 is provided to prevent external debris from entering the filter box 101 through the funnel 102 during filtration, thereby preventing the filtration from affecting the filtration. When the cell extract needs to be poured into the filter box 101, the top cover 203 can be pushed upward, and then driven to rotate with the cooperation of the rotating shaft 202, so that the top cover 203 and the funnel 102 are out of the adaptation state.

[0037] The two fixing rods 201 are symmetrically arranged at the upper ends of the filter box 101, the rotating shaft 202 is rotatably connected to the two fixing rods 201 and is located between the two fixing rods 201, the top cover 203 covers the upper end of the funnel 102, and the left end of the top cover 203 is fixedly connected to the rotating shaft 202. The setting of the top cover 203 prevents external debris from entering the filter box 101 through the funnel 102 during filtration, thereby affecting filtration. When it is necessary to pour the cell extract into the filter box 101, the top cover 203 can be pushed upward, and then driven to rotate with the cooperation of the rotating shaft 202, so that the top cover 203 and the funnel 102 are out of the adaptation state.

[0038] When using a continuous filtering device for tissue extract of the present embodiment, the top cover 203 is provided to prevent external debris from entering the filter box 101 through the funnel 102 during filtration and affecting the filtration. When it is necessary to pour the cell extract into the filter box 101, the top cover 203 can be pushed upward and then driven to rotate with the cooperation of the rotating shaft 202, so that the top cover 203 and the funnel 102 are out of the adaptation state.

[0039] What is disclosed above is only one or more preferred embodiments of the present application, and cannot be used to limit the scope of rights of the present application. Ordinary technicians in this field can understand that all or part of the processes of implementing the above embodiments and equivalent changes made according to the claims of the present application are still within the scope covered by the present application.

Claims

1. A continuous filtration device for tissue extract, characterized in that: Includes filter box, funnel and filter assembly; The filter assembly includes a filter plate, a guide plate, a conduit, a box, a water pump, a first connecting pipe and a second connecting pipe. The right side of the filter box has an opening, the funnel is connected to the filter box and is located at the top of the filter box, the filter plate is arranged inside the filter box, and the right end of the filter plate is located below the opening, the guide plate is arranged inside the filter box and is located below the filter plate, the box is fixedly connected to the left side of the filter box, one end of the conduit is connected to the left side of the filter box, and the other end of the conduit is connected to the top of the box, the water pump is fixedly connected to the left side of the box, one end of the first connecting pipe is connected to the left side of the box, the other end of the first connecting pipe is fixedly connected to the bottom of the water pump, one end of the second connecting pipe is fixedly connected to the top of the water pump, and the other end of the second connecting pipe is connected to the top of the filter box.

2. The continuous filtration device for tissue extract according to claim 1, characterized in that: The filter assembly further includes a liquid outlet pipe and a first solenoid valve. The liquid outlet pipe is communicated with the box body and is located at the bottom of the box body. The first solenoid valve is arranged on the liquid outlet pipe.

3. The continuous filtration device for tissue extract according to claim 2, characterized in that: The filter assembly further includes a guide pipe, which is fixedly connected to the right side surface of the filter box, and the left end of the guide pipe is communicated with the opening.

4. The continuous filtration device for tissue extract according to claim 3, characterized in that: The continuous filtering device for tissue extract further comprises a plurality of supporting legs, one end of each of which is fixedly connected to the filter box and is located around the bottom of the filter box.

5. The continuous filtration device for tissue extract according to claim 4, characterized in that: The continuous filtering device for tissue extract also includes a collecting tank, which is placed on the ground and located directly below the liquid outlet pipe.

6. The continuous filtration device for tissue extract according to claim 5, characterized in that: The continuous filtering device for tissue extract also includes a water tank, a first water pipe, a second water pipe, a plurality of nozzles and a second solenoid valve. The water tank is fixedly connected to the filter box and is located on the top of the filter box. One end of the first water pipe is connected to the front surface of the water tank, and the other end of the first water pipe passes through the top of the filter box and is connected to the middle section of the second water pipe. The second water pipe is arranged inside the filter box and is located above the filter plate. The plurality of nozzles are respectively arranged at the lower end of the second water pipe, and the second solenoid valve is arranged on the first water pipe.

7. The continuous filtration device for tissue extract according to claim 6, characterized in that: The continuous filtering device for tissue extract also includes a box cover, which is rotatably connected to the water tank and is located on the top of the water tank.

8. The continuous filtration device for tissue extract according to claim 7, characterized in that: The continuous filtering device for tissue extract further comprises a handle, which is fixedly connected to the box cover and is located at the upper end of the box cover.

9. The continuous filtration device for tissue extract according to claim 8, characterized in that: The continuous filtering device for tissue extract also includes two fixed rods, a rotating shaft and a top cover. The two fixed rods are symmetrically arranged at the upper ends of the filter box, the rotating shaft is rotatably connected to the two fixed rods and is located between the two fixed rods. The top cover covers the upper end of the funnel, and the left end of the top cover is fixedly connected to the rotating shaft.

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