Local heat dissipation device for miniaturized PCR instrument

Abstract

The utility model provides a local heat dissipation device for a miniaturized PCR (Polymerase Chain Reaction) instrument. The local heat dissipation device comprises a base, a heat conduction assembly and a heat dissipation assembly, a heat source is fixed to one side of the base, and the other side of the base is connected with a heat conduction assembly. The heat conduction assembly comprises a heat conduction base and a heat conduction guide pipe, the heat conduction base is connected with the base, the heat conduction guide pipe comprises a pipeline set or multiple spaced pipeline sets, each pipeline set comprises a heat conduction part, a first heat dissipation part and a second heat dissipation part, and the heat conduction guide pipe is connected between the heat conduction assembly and the heat dissipation fin set in a penetrating mode; the heat dissipation assembly comprises a heat dissipation fin set, a support and a fan, the heat dissipation fin set is fixed to one end of the support, the fan is fixed to the other end of the support, a plurality of spaced heat dissipation fins are arranged in the length direction of the heat dissipation fin set, and the fan, the heat dissipation fin set and the heat source are located on the same straight line, so that the fan can directly conduct heat dissipation on the heat dissipation fin set and the heat source. The heat dissipation device can quickly and uniformly transfer heat, and meanwhile, miniaturization and integration are realized.

Description

Technical Field

[0001] The utility model belongs to the technical field of PCR instruments, and in particular relates to a local heat dissipation device for a miniaturized PCR instrument. Background Art

[0002] Since its invention in the 20th century, polymerase chain reaction (PCR) has provided great convenience for medical and biological research by expanding the identification and replication of genetic materials such as DNA. It is now widely used in genetic disease detection, genetic fingerprint recognition, infectious disease diagnosis, gene cloning, paternity testing and DNA computing. What has emerged is the PCR instrument, an automated device that can realize genetic material amplification detection. During the PCR reaction process, different reaction stages correspond to different temperatures in order to successfully amplify the genetic material in the sample to be tested. Therefore, the current research hotspot of those skilled in the art is how to quickly, accurately and evenly control the temperature of each stage.

[0003] In order to meet the detection needs of large-throughput samples, traditional PCR instruments are generally provided with more than four heating elements. In order to facilitate the rapid adjustment of the temperature range, a larger heat dissipation device is provided. The Chinese patent with publication number CN116103143A discloses a PCR base and a PCR instrument, which are provided with four cooling fins, the heat dissipation fins are close to the cooling fins, and the fan is arranged on the opposite side of the heat dissipation fins. In such a top-mounted arrangement, the airflow needs to change direction in the heat dissipation fins, and there is a wind blind area that affects the heat dissipation efficiency of the heating element. The US patent with publication number US20060065652A1 discloses a thermal cycling method for biological material samples with significant temperature uniformity, wherein the radiator includes a plurality of parallel rectangular fins extending downward from the base, and the top of the radiator is close to the heat block, and a plurality of resistance element heaters are provided on the top surface of the radiator base. In this design, during the cooling process, the heat in the heater will be preferentially transferred to the rectangular fins that are close to it. The utilization rate of the fins far away from the heater is low. At the same time, the space utilization rate around the heat source is low. In order to facilitate the installation of other components, technicians can only expand other spaces, resulting in a larger volume of the entire device. Therefore, it is urgent to develop a heat dissipation device that can quickly and evenly transfer heat while having a small space volume to meet the needs of miniaturization and integration. Utility Model Content

[0004] In order to solve the above problems existing in the prior art, the utility model is implemented through the following technical solutions:

[0005] The utility model provides a local heat dissipation device for a miniaturized PCR instrument, comprising a base, a heat conduction component, and a heat dissipation component, wherein a heat source is fixed on one side of the base, and the other side of the base is connected to the heat conduction component; the heat conduction component comprises a heat transfer base and a heat transfer conduit, the heat transfer base is connected to the base for heat transfer, the heat transfer conduit comprises a group of pipe groups or a plurality of groups of pipe groups arranged at intervals, each group of pipe groups comprises a heat conduction part, a first heat dissipation part and a second heat dissipation part, the heat conduction part is embedded in the heat transfer base, the first heat dissipation part penetrates the heat dissipation fin group along the length direction of the heat dissipation fin group in the heat dissipation component and then connects to the first end of the heat conduction part, the second heat dissipation part penetrates the heat dissipation fin group along the length direction of the heat dissipation fin group in the heat dissipation component and then connects to the second end of the heat conduction part; the penetrating direction of the first heat dissipation part in the heat dissipation fin group is different from the penetrating direction of the second heat dissipation part in the heat dissipation fin group; the heat dissipation component comprises a heat dissipation fin group, a bracket and a fan.

[0006] In one embodiment of the utility model, the first end of the bracket fixes the heat dissipation fin group, the second end of the bracket fixes the fan, a plurality of heat dissipation fins are arranged along the length direction of the heat dissipation fin group, the heat transfer pipe passes through the plurality of heat dissipation fins, the fan, the heat dissipation fin group and the heat source are located in the same straight line position, so that the fan can directly dissipate heat to the heat dissipation fin group and the heat source.

[0007] In one embodiment of the utility model, the heat conducting part is a first transverse tube that passes through the heat transfer base and is embedded in the heat transfer base, the first heat dissipation part includes a first curved tube and a second transverse tube that are connected to each other, the second transverse tube passes through the heat dissipation fins along the length direction of the heat dissipation fin group and is connected to the first end of the first curved tube, the second end of the first curved tube is connected to the first end of the first transverse tube, the second heat dissipation part includes a second curved tube and a third transverse tube that are connected to each other, the third transverse tube passes through the heat dissipation fins along the length direction of the heat dissipation fin group and is connected to the first end of the second curved tube, the second end of the second curved tube is connected to the second end of the first transverse tube, and the heat dissipation fin group is arranged between the fan and the heat conducting component.

[0008] In one embodiment of the present invention, the second transverse tube and the third transverse tube are arranged in the heat dissipation fins at intervals and through the heat dissipation fin group along the length direction of the heat dissipation fin group.

[0009] In one embodiment of the utility model, the heat conducting part, the first heat dissipating part and the second heat dissipating part are enclosed to form a hollow structure, so that there is a gap between the base and the heat dissipating fin group, so as to facilitate the installation of structural parts of the PCR device in the gap between the base and the heat dissipating fin group.

[0010] In one embodiment of the present invention, the interior of the heat transfer conduit is filled with an inert gas medium or a heat transfer fluid.

[0011] In one embodiment of the present invention, the heat conduction assembly further comprises a mounting plate, and the mounting plate tightly connects the heat transfer base and the pedestal.

[0012] In one embodiment of the utility model, there is a gap between adjacent heat dissipation fins; the length direction of each heat dissipation fin is perpendicular to the length direction of the heat dissipation fin group, and the air outlet of the fan is opposite to the gap between adjacent heat dissipation fins in the heat dissipation fin group.

[0013] In an embodiment of the present invention, the center position of the bracket is a hollow structure, and the airflow generated by the fan can directly enter the gap between adjacent heat dissipation fins through the hollow structure.

[0014] In an embodiment of the present invention, the base is made of aluminum alloy, and the heat transfer base and the heat transfer pipe are made of copper.

[0015] Compared with the prior art, the beneficial effects of the utility model are:

[0016] 1. The local heat dissipation device for a miniaturized PCR instrument provided by the utility model connects the heat source with the heat dissipation fin group through a heat conduction component, and sets a plurality of heat transfer pipes including a heat conduction part and two heat dissipation parts, which not only increases the heat exchange area and improves the heat transfer efficiency, but also improves the air volume utilization rate of the fan and the uniformity of heat dissipation of the heat source; the design of the position and direction of the heat transfer pipe, as well as the position and direction of the fan, the heat dissipation fin group and the heat source, makes the heat dissipation wind direction in the best design path, has a higher degree of freedom, and makes full use of the heat dissipation effect of the internal area of ​​the heat dissipation fin group.

[0017] 2. The utility model provides a local heat dissipation device for a miniaturized PCR instrument, and a gap exists between the heat dissipation fin group and the heat source, so that the space around the heat source is released, which is convenient for installing other components or facilitating the movement of other components, thereby meeting the heat dissipation needs of miniaturized and integrated devices.

[0018] 3. The utility model has a simple overall structure, good compatibility, low production cost, and greatly improves work efficiency.

[0019] The present invention will be further described in detail below with reference to the accompanying drawings and embodiments. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 It is a structural schematic diagram of a local heat dissipation device for a miniaturized PCR instrument provided by an embodiment of the utility model;

[0021] Figure 2 yes Figure 1 Schematic diagram of the explosion structure;

[0022] Figure 3 yes Figure 1 A schematic diagram of a top view structure;

[0023] Figure 4 yes Figure 1 Schematic diagram of the left view structure.

[0024] Description of reference numerals:

[0025] 100- base; 101- heat source;

[0026] 201-heat transfer base; 202-mounting plate; 203-heat transfer conduit;

[0027] 301-heat sink fin assembly; 302-bracket; 303-fan. DETAILED DESCRIPTION

[0028] In order to further explain the technical means and effects adopted by the present invention to achieve the predetermined purpose of the present invention, the scheme according to the present invention is described in detail below in conjunction with the accompanying drawings and specific implementation methods.

[0029] The above and other technical contents, features and effects of the utility model are clearly presented in the following detailed description of the specific implementation mode in conjunction with the accompanying drawings. Through the description of the specific implementation mode, the technical means and effects adopted by the utility model to achieve the predetermined purpose can be more deeply and specifically understood. However, the attached drawings are only for reference and explanation, and are not used to limit the technical solution of the utility model.

[0030] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants are intended to cover non-exclusive inclusion, so that an article or device including a series of elements includes not only those elements, but also other elements that are not explicitly listed. In the absence of more restrictions, the elements defined by the statement "including one..." do not exclude the existence of other identical elements in the article or device including the elements.

[0031] See also Figure 1 and Figure 2 , Figure 1 This is a schematic diagram of the structure of a local heat dissipation device for a miniaturized PCR instrument provided by an embodiment of the utility model. Figure 2 yes Figure 1The local heat dissipation device for a miniaturized PCR instrument comprises a base 100, a heat conducting component, and a heat dissipation component.

[0032] Specifically, a heat source is fixed on one side of the base 100, and a heat conduction component is connected to the other side of the base 100. The heat conduction component includes a heat transfer base 201 and a heat transfer conduit 203. The heat transfer base 201 is connected to the base 100 for heat transfer. The heat transfer conduit 203 includes a group of pipe groups or multiple groups of pipe groups arranged at intervals. Each group of pipe groups includes a heat conduction part, a first heat dissipation part and a second heat dissipation part. The heat conduction part is embedded in the heat transfer base 201. The first heat dissipation part penetrates the heat dissipation fin group 301 along the length direction of the heat dissipation fin group 301 in the heat dissipation component and then connects to the first end of the heat conduction part. The second heat dissipation part penetrates the heat dissipation fin group 301 along the length direction of the heat dissipation fin group 301 in the heat dissipation component and then connects to the second end of the heat conduction part. The penetrating direction of the first heat dissipation part in the heat dissipation fin group 301 is different from the penetrating direction of the second heat dissipation part in the heat dissipation fin group 301. In other words, the main body direction of the first heat dissipation part is different from the main body direction of the second heat dissipation part. The heat dissipation assembly includes a heat dissipation fin group 301, a bracket 302 and a fan 303. The first end of the bracket 302 fixes the heat dissipation fin group 301, and the second end of the bracket 302 fixes the fan 303. A plurality of heat dissipation fins are arranged along the length direction of the heat dissipation fin group 301. The heat transfer pipe 203 runs through the plurality of heat dissipation fins. The fan 303, the heat dissipation fin group 301 and the heat source are located in the same straight line position, so that the fan 303 can directly dissipate heat from the heat dissipation fin group 301 and the heat source. In the local heat dissipation device for a miniaturized PCR instrument provided in this embodiment, the heat conduction assembly connects the heat source with the heat dissipation fin group, and multiple groups of heat transfer pipes including a heat conduction part and two heat dissipation parts are arranged. The local heat dissipation device not only increases the heat exchange area and improves the heat transfer efficiency, but also improves the air volume utilization rate of the fan and the uniformity of heat dissipation of the heat source. The structural design of the heat transfer pipe makes full use of the heat dissipation effect of the internal area of ​​the heat dissipation fin group. The position and direction design of the fan, the heat dissipation fin group and the heat source in the same straight line position makes the heat dissipation wind direction in the best design path, with a higher degree of freedom.

[0033] Furthermore, in order to reduce processing costs while meeting basic heat transfer efficiency requirements, the base 100 is made of aluminum alloy, and the heat transfer base 201 and the heat transfer conduit 203 are made of copper, which improves heat transfer efficiency while reducing the manufacturing cost of the local heat dissipation device for a miniaturized PCR instrument.

[0034] In this embodiment, the base 100 is a rectangular plate made of metal material. A heat source 101 is tightly fixed to one side of the base 100 by screws. The heat source 101 is used to provide the required heat for the PCR reaction. A heat conductive component is tightly fixed to the other side of the base 100. The heat conductive component connects the base 100 to the heat dissipation component. The heat conductive component can transfer the heat on the heat source 101 to the heat dissipation component, thereby improving the heat exchange efficiency, so that the PCR instrument can maintain the temperature required for the reaction.

[0035] Preferably, the heat transfer assembly further includes a mounting plate 202, which tightly connects the heat transfer base 201 to the base 100. In this embodiment, the heat transfer base 201 is a rectangular metal plate with a certain heat capacity, and the length, width and thickness of the heat transfer base 201 are 60mm×34mm×5.5mm respectively. The heat transfer base 201 is tightly fixed to the base 100 through the mounting plate 202; specifically, the first side of the heat transfer base 201 is adjacent to the base 100, and the mounting plate 202 is arranged on the second side ( Figure 2 In order to facilitate the display of various components, the mounting plate 202 is not shown on the side wall of the heat transfer base 201. The mounting plate 202 tightly fixes the heat transfer base 201 and the base 100 together. The heat transfer pipe 203 is connected between the heat transfer base 201 and the heat dissipation fin group 301. Specifically, the interval positions of the heat dissipation fins in the heat dissipation fin group 301 are provided with mounting holes capable of accommodating the heat transfer pipe 203. The heat transfer pipe 203 is fixedly installed inside a plurality of heat dissipation fins by welding.

[0036] Further, in the pipeline group included in the heat transfer pipe 203, each pipeline group includes a heat conduction part and two heat dissipation parts, the heat conduction part is a first transverse tube that penetrates the heat transfer base 201 and is embedded in the heat transfer base 201, the first heat dissipation part includes a first elbow and a second transverse tube that are connected, the second transverse tube penetrates the heat dissipation fins along the length direction of the heat dissipation fin group 301 and is connected to the first end of the first elbow, the second end of the first elbow is connected to the first end of the first transverse tube, the second heat dissipation part includes a second elbow and a third transverse tube that are connected, the third transverse tube penetrates the heat dissipation fins along the length direction of the heat dissipation fin group 301 and is connected to the first end of the second elbow, the second end of the second elbow is connected to the second end of the first transverse tube, so that the heat conduction part and the two heat dissipation parts are integrally formed to form an integrated pipeline group. In addition, the heat dissipation fin group 301 is arranged opposite to the heat source 101, and preferably, the heat dissipation fin group 301 is arranged between the fan 303 and the heat conduction component.

[0037] Preferably, the second transverse tube and the third transverse tube are arranged in the heat dissipating fins at intervals along the length direction of the heat dissipating fin group 301; since the positions at which the second transverse tube and the third transverse tube pass through the heat dissipating fins are different, the contact area between the pipe group and the heat dissipating fins in the heat dissipating fin group 301 is increased, thereby improving the heat dissipation efficiency of the internal area of ​​the heat dissipating fin group 301.

[0038] Preferably, when there are multiple pipe groups, adjacent pipe groups are spaced apart from each other, thereby increasing the heat exchange area to improve the efficiency of heat energy obtained by the heat transfer pipe 203 from the heat transfer base 201 and the heat exchange rate between the heat transfer pipe 203 and the heat dissipation fin group 301. In the present embodiment, two groups of pipe groups are provided, and the two groups of pipe groups are spaced apart from each other. The gaps between the heat dissipating fins in the heat dissipating fin group 301 are arranged opposite to the heat source. The local heat dissipation device for a miniaturized PCR instrument provided in the present embodiment is provided with a heat conducting portion embedded in the heat dissipating base 201 along the length direction of the heat dissipating base 201, thereby increasing the contact area between the heat dissipating pipe 203 and the heat dissipating base 201, and increasing the efficiency of the heat energy obtained by the heat dissipating pipe 203 from the heat dissipating base 201. At the same time, the two heat dissipating portions penetrate the heat dissipating fins in the heat dissipating fin group 301 in opposite directions along the length direction of the heat dissipating fin group 301, thereby increasing the contact area between the heat dissipating pipe 203 and the heat dissipating fins in the heat dissipating fin group 301, making full use of the heat dissipation area inside the heat dissipating fin group 301, and further improving the heat exchange rate between the heat dissipating pipe 203 and the heat dissipating fin group 301.

[0039] Furthermore, if Figure 3 As shown, the heat conducting part, the first heat dissipating part and the second heat dissipating part are enclosed to form a hollow structure, so that there is a gap between the base 100 and the heat dissipating fin group 301, so as to facilitate the installation of other structural parts of the PCR device in the gap between the base 100 and the heat dissipating fin group 301. The local heat dissipation device for a miniaturized PCR instrument provided in this embodiment releases the space around the heat source by improving the structural compactness of the PCR instrument device, which is convenient for installing other components or facilitating the movement of other components, and at the same time, it is convenient to improve the utilization rate of the fan air volume, so as to meet the heat dissipation needs of miniaturized and integrated devices. In this embodiment, the heat transfer conduit 203 includes two groups of pipe groups arranged at intervals, each group of pipe groups includes three transverse pipes and two elbows, and the transverse pipes and the elbows are integrally formed to form a hollow structure. Specifically, a transverse tube of the heat transfer pipe 203 is embedded in the heat transfer base 201 and extends from the two side walls of the heat transfer base 201. In order to increase the heat exchange area, the two ends of the first transverse tube embedded in the heat transfer base 201 are connected to the second transverse tube and the third transverse tube through elbows, respectively, and the second transverse tube and the third transverse tube are spaced to pass through the heat dissipation fin group 301. In addition, the shape of the heat transfer pipe 203 can also be set to a linear or U-shaped shape, and its specific bending direction can be set according to the actual design path, thereby improving the design freedom of the device. In other embodiments, the transverse tube and the elbow can also be other numbers.

[0040] Preferably, the interior of the heat transfer conduit 203 is filled with an inert gas medium or a heat transfer fluid. The interior of the heat transfer conduit 203 may be filled with a gas or a heat transfer liquid, such as water or alcohol, to further enhance the heat transfer efficiency.

[0041] Preferably, there are gaps between adjacent heat sink fins. Specifically, the spacing between the heat sink fins can be set at equal intervals, for example, a plurality of heat sink fins are set at intervals along the length direction of the heat sink fin group 301, and the spacing between the heat sink fins is the same. The same spacing between the heat sink fins can make the collected heat more uniform, or the spacing between the heat sink fins can be different. By setting gaps between the heat sink fins, energy can be collected between the heat sink fins.

[0042] Furthermore, the length direction of each heat dissipating fin is perpendicular to the length direction of the heat dissipating fin group 301, and the air outlet of the fan 303 is opposite to the gap between adjacent heat dissipating fins in the heat dissipating fin group 301. After blowing air, the fan 303 can directly dissipate the heat energy collected in the gap between the heat dissipating fins, thereby improving the heat dissipation efficiency.

[0043] Furthermore, the center position of the bracket 302 is hollowed out, so that the airflow generated by the fan 303 can directly enter the gap between adjacent heat dissipation fins. Specifically, in order to enhance the heat dissipation efficiency, the air outlet of the fan 303 is opposite to the gap between the heat dissipation fins in the heat dissipation fin group 301. Since the center position of the bracket 302 is a hollow structure, the wind force generated by the fan 303 directly contacts the heat dissipation fin group 301 through the hollow structure, so that the heat dissipation effect between the fan 303 and the heat dissipation fin group 301 and the heat transfer pipe 203 is good.

[0044] In this embodiment, the size of the fan is 60 mm × 60 mm, and the power is 12 W. Figure 4 As shown, the fan 303 is fixedly mounted on the outside of the bracket 302 by screws, and a plurality of heat dissipation fins are vertically fixed on the inside of the bracket 302 opposite to the base 100. There is a gap between the base 100 and the heat dissipation fin group 301, so as to facilitate the installation of additional PCR instrument structural parts around the heat source 101, improve the structural compactness of the PCR instrument device, and at the same time facilitate the improvement of the utilization rate of the fan air volume. The local heat dissipation device for a miniaturized PCR instrument provided in this embodiment can achieve an average cooling rate of 8°C / s.

[0045] The following describes the use of the local heat dissipation device for a miniaturized PCR instrument provided by the utility model in stages:

[0046] S10, preparation stage;

[0047] The element capable of performing PCR amplification reaction is placed in close contact with the heat source 101, specifically Figure 1 On the left side of the heat source 101, the Peltier effect of the heat source 101 is used to heat / cool the PCR amplification reaction element.

[0048] S20, high temperature denaturation stage;

[0049] In the heating stage, the heat source 101 starts to transfer heat to the PCR amplification reaction element, so that the temperature of the PCR amplification reaction element can be maintained between 90° C. and 97° C., thereby achieving high-temperature denaturation of the nucleic acid of the sample to be tested;

[0050] S30, low temperature annealing stage;

[0051] When the PCR reaction reaches the low-temperature annealing stage, 45°C-55°C is required, and the working mode of the heat source 101 is changed to a cooling state. In order to facilitate rapid cooling, the fan 303 is started at this time, and the heat generated by the lower surface of the heat source 101 is quickly diffused and transferred to the heat transfer pipe 203 through the heat transfer base 201. The heat transfer medium inside the heat transfer pipe 203 absorbs the heat and directly transfers the heat to the heat dissipation fin group 301, and forced convection heat is dissipated under the action of the fan 303. Since the heat source 101, the heat transfer base 201, the heat dissipation fin group 301 and the fan 303 are in the same direction, that is, the heat transfer base 201, the heat dissipation fin group 301 and the fan 303 are in the same straight line direction, and there is a certain gap distance between the heat dissipation fin group 301 and the heat transfer base 201, the air volume generated by the fan 303 can be utilized to a greater extent, thereby improving the heat exchange efficiency.

[0052] S40: PCR reaction is extended to the optimum temperature.

[0053] When the PCR reaction reaches the temperature extension stage, 72° C. is required. At this time, the heat source 101 continues to heat, so that the PCR amplification reaction element is maintained at the temperature conditions required for the PCR amplification reaction and all amplification reactions are completed.

[0054] The local heat dissipation device for a miniaturized PCR instrument provided in this embodiment has a simple overall structure, good compatibility, low manufacturing cost, and greatly improves work efficiency.

[0055] The above contents are further detailed descriptions of the present invention in combination with specific preferred implementations, and the specific implementation of the present invention cannot be considered to be limited to these descriptions. For ordinary technicians in the technical field to which the present invention belongs, several simple deductions or substitutions can be made without departing from the concept of the present invention, which should be regarded as falling within the protection scope of the present invention.

Claims

1. A local heat dissipation device for a miniaturized PCR instrument, characterized in that: It comprises a base (100), a heat-conducting component, and a heat-dissipating component, wherein: A heat source is fixed on one side of the base (100), and a heat conduction component is connected to the other side of the base (100); The heat transfer component comprises a heat transfer base (201) and a heat transfer conduit (203); the heat transfer base (201) is connected to the base (100) for heat transfer; the heat transfer conduit (203) comprises a group of pipe groups or a plurality of groups of pipe groups arranged at intervals; each group of pipe groups comprises a heat transfer portion, a first heat dissipation portion and a second heat dissipation portion; the heat transfer portion is embedded in the heat transfer base (201); the first heat dissipation portion penetrates the heat dissipation fin group (301) along the length direction of the heat dissipation fin group (301) in the heat dissipation component and is then connected to the first end of the heat transfer portion; the second heat dissipation portion penetrates the heat dissipation fin group (301) along the length direction of the heat dissipation fin group (301) in the heat dissipation component and is then connected to the second end of the heat transfer portion; the penetration direction of the first heat dissipation portion in the heat dissipation fin group (301) is different from the penetration direction of the second heat dissipation portion in the heat dissipation fin group (301); The heat dissipation component comprises a heat dissipation fin group (301), a bracket (302) and a fan (303).

2. The local heat dissipation device for a miniaturized PCR instrument according to claim 1, characterized in that: The first end of the bracket (302) fixes the heat dissipation fin group (301), and the second end of the bracket (302) fixes the fan (303). A plurality of heat dissipation fins are arranged along the length direction of the heat dissipation fin group (301). The heat transfer pipe (203) passes through the plurality of heat dissipation fins. The fan (303) is located in the same straight line as the heat dissipation fin group (301) and the heat source, so that the fan (303) can directly dissipate heat from the heat dissipation fin group (301) and the heat source.

3. The local heat dissipation device for a miniaturized PCR instrument according to claim 1, characterized in that: The heat conduction part is a first transverse tube that passes through the heat transfer base (201) and is embedded in the heat transfer base (201); the first heat dissipation part comprises a first curved tube and a second transverse tube that are connected to each other; the second transverse tube passes through the heat dissipation fins along the length direction of the heat dissipation fin group (301) and is connected to the first end of the first curved tube; the second end of the first curved tube is connected to the first end of the first transverse tube; the second heat dissipation part comprises a second curved tube and a third transverse tube that are connected to each other; the third transverse tube passes through the heat dissipation fins along the length direction of the heat dissipation fin group (301) and is connected to the first end of the second curved tube; the second end of the second curved tube is connected to the second end of the first transverse tube; and the heat dissipation fin group (301) is arranged between the fan (303) and the heat conduction component.

4. The local heat dissipation device for a miniaturized PCR instrument according to claim 3, characterized in that: The second transverse tube and the third transverse tube are arranged in the heat dissipation fins at intervals and through the heat dissipation fin group (301) along the length direction of the heat dissipation fin group (301).

5. The local heat dissipation device for a miniaturized PCR instrument according to claim 3, characterized in that: The heat conducting portion, the first heat dissipating portion and the second heat dissipating portion are enclosed to form a hollow structure, so that a gap exists between the base (100) and the heat dissipating fin group (301), so as to facilitate installation of structural components of the PCR device in the gap between the base (100) and the heat dissipating fin group (301).

6. The local heat dissipation device for a miniaturized PCR instrument according to claim 1, characterized in that: The interior of the heat transfer conduit (203) is filled with an inert gas medium or a heat transfer fluid.

7. The local heat dissipation device for a miniaturized PCR instrument according to claim 1, characterized in that: The heat conduction assembly further comprises a mounting plate (202), wherein the mounting plate (202) tightly connects the heat transfer base (201) and the pedestal (100).

8. The local heat dissipation device for a miniaturized PCR instrument according to claim 1, characterized in that: There are gaps between adjacent heat dissipation fins; the length direction of each heat dissipation fin is perpendicular to the length direction of the heat dissipation fin group (301); and the air outlet of the fan (303) is opposite to the gaps between adjacent heat dissipation fins in the heat dissipation fin group (301).

9. The local heat dissipation device for a miniaturized PCR instrument according to claim 1, characterized in that: The center position of the bracket (302) is a hollow structure, and the airflow generated by the fan (303) can directly enter the gap between adjacent heat dissipation fins through the hollow structure.

10. The local heat dissipation device for a miniaturized PCR instrument according to any one of claims 1 to 9, characterized in that: The base (100) is made of aluminum alloy material, and the heat transfer base (201) and the heat transfer conduit (203) are made of copper material.

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