Observation equipment for cell depletion research

Abstract

The utility model discloses observation equipment for cell depletion research, and relates to the technical field of cell research equipment, the observation equipment comprises a mounting rack and a carrying seat, the front side of the mounting rack is fixedly provided with a placing rack, the placing rack is internally provided with a microscope body, the right side of the mounting rack is provided with a controller, and a fine tuning mechanism is arranged between the mounting rack and the carrying seat. A clamping mechanism is arranged on the surface of the carrying base and comprises a containing groove formed in the upper surface of the carrying base. According to the observation equipment for cell depletion research disclosed by the utility model, through the arrangement of the pressing plate, a slide sample is placed on the carrying seat, the screw rod is rotated, and the threaded barrel drives the connecting rod and the pressing plate to move downwards under the rotation of the screw rod until the slide sample is pressed against the carrying seat by the pressing plate, so that the slide sample can be fixed; therefore, the device can achieve the purpose of fixing the slide, and the situation that the slide falls off and displaces when the position of the carrying seat is adjusted subsequently is avoided.

Description

Technical Field

[0001] The utility model relates to the technical field of cell research equipment, in particular to an observation device for cell exhaustion research. Background Art

[0002] Immune cell exhaustion refers to a pathological state in which the number of certain immune cells in the body's immune system is significantly reduced or their functions are impaired, resulting in a decline in the body's immune function. In order to develop corresponding vaccines for various diseases, medical personnel need to use microscopes to study and observe cells and tissues.

[0003] The patent document with the publication number CN220913433U discloses a microscope for microbiological research, which relates to the field of microscope technology, improves the phenomenon that it is not convenient to fine-tune the position of the slide, which limits the scope of observation, affects the convenience of use, and is not convenient to adjust the height of the eyepiece, including a slot plate, a fine-tuning shift component is fixedly connected to the bottom of the slot plate, and the fine-tuning shift component includes two side slot frames symmetrically and evenly distributed on both sides of the slot plate, the inner wall of the side slot frame is movably connected to a sliding rotating frame, the other end of the sliding rotating frame is fixedly connected to a connecting rod, the other end of the connecting rod is fixedly connected to a positioning rotating frame, and a slide frame plate is fixedly connected between the two positioning rotating frames, and the rear end of the slide frame plate is fixedly connected to a first threaded rod, and the outer wall of the first threaded rod is movably connected to an adjusting nut. The present application can fine-tune the position of the slide structure to adjust the range of observation of microorganisms in the slide.

[0004] With respect to the above-mentioned related technologies, the inventors believe that the following defects exist: the above-mentioned scheme lacks a mechanism for fixing the glass slide specimens during actual use, which results in the glass slide carrying the specimens easily falling off and shifting on the slide rack when personnel push the connecting rod to adjust the position of the specimens, causing inconvenience to subsequent cell research and observation work, and the adjustment method driven by manpower has poor stability and is prone to excessive displacement due to excessive force, making it inconvenient to fine-tune its position. Utility Model Content

[0005] The utility model discloses an observation device for cell exhaustion research, aiming to solve the technical problem that the existing cell research equipment lacks the ability to fix glass slide specimens.

[0006] In order to achieve the above purpose, the utility model adopts the following technical solutions:

[0007] An observation device for cell exhaustion research comprises a mounting frame and a carrier seat, a placement frame is fixedly mounted on the front of the mounting frame, a microscope body is mounted inside the placement frame, a controller is arranged on the right side of the mounting frame, a fine adjustment mechanism is arranged between the mounting frame and the carrier seat, and a clamping mechanism is arranged on the surface of the carrier seat;

[0008] The clamping mechanism includes a storage groove opened on the upper surface of the carrier, a rotating opening penetrating into the interior of the storage groove opened on the lower surface of the carrier, a screw rod extending into the interior of the storage groove is rotatably connected to the inner wall of the rotating opening, a threaded barrel is threadedly connected to the surface of the screw rod, a connecting rod is fixedly connected to the upper end of the threaded barrel, and two symmetrical pressure plates are fixedly connected to the front side of the connecting rod.

[0009] In a preferred solution, a light-through hole is formed through the surface of the object carrier, and a reflector corresponding to the position of the light-through hole is mounted on the lower surface of the object carrier via an L-shaped frame.

[0010] In a preferred solution, both side surfaces of the threaded barrel are provided with limit sliding blocks, and both side inner walls of the receiving groove are provided with limit sliding grooves for the limit sliding blocks to slide.

[0011] By arranging a limit slider, under the guiding action of the limit slider, the threaded barrel can be moved up and down in a directional manner through the rotation of the screw rod.

[0012] In a preferred solution, a flexible cushion layer is provided on the lower surface of the pressing plate, and the flexible cushion layer is made of silicone material.

[0013] The flexible cushion layer can be provided to protect the glass slide sample when the pressing plate presses the glass slide sample.

[0014] In a preferred embodiment, the fine-tuning mechanism includes a mounting frame embedded in the front side of the mounting frame, a motor is fixedly mounted on the right end of the mounting frame, the output shaft of the motor extends to the interior of the mounting frame and is fixedly connected to a threaded rod, a threaded block is threadedly connected to the surface of the threaded rod, a connecting frame is fixedly mounted on the front side of the threaded block, an electric push rod is embedded in the inner rear wall of the connecting frame, and the telescopic end of the electric push rod is fixedly connected to the back side of the loading seat.

[0015] By setting the motor and the electric push rod, the lateral and longitudinal positions of the object carrier can be adjusted respectively.

[0016] In a preferred solution, a guide slide block is provided on the back side of the threaded block, and a guide slide groove for the guide slide block to slide is provided on the inner rear wall of the mounting frame.

[0017] By setting the guide slide block, the threaded block can be moved left and right in a directional manner through the rotation of the threaded rod.

[0018] In a preferred solution, mounting slide blocks are provided on both side surfaces of the object carrier, and mounting grooves adapted to the mounting slide blocks are provided on both side inner walls of the connecting frame.

[0019] By installing the slider, the load-bearing function can be assisted on the load-bearing seat, thus preventing all gravity from acting on the electric push rod.

[0020] From the above, it can be seen that the observation device for cell exhaustion research provided by the utility model has the following technical effects.

[0021] First, place the glass slide sample on the stage, rotate the screw, and the threaded tube drives the connecting rod and the pressure plate downward under the rotation of the screw until the pressure plate presses the glass slide sample against the stage to fix it. This allows the device to fix the glass slide and prevent the glass slide from falling or shifting when the position of the stage is adjusted later.

[0022] Secondly, the operation of the motor drives the threaded rod to rotate, and the threaded block drives the connecting frame and the sample holder to move left and right through the rotation of the threaded rod, so that the lateral position of the glass slide sample can be adjusted. At the same time, the operation of the electric push rod pushes the sample holder to move back and forth in the connecting frame, so that the longitudinal position of the glass slide sample can be adjusted. The operation is simple and the fine-tuning accuracy is high, avoiding excessive adjustment due to human push. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 This is a schematic diagram of the three-dimensional structure of an observation device for cell exhaustion research proposed by the utility model.

[0024] Figure 2 This is a schematic diagram of the top-sectional structure of the installation frame of an observation device for cell exhaustion research proposed by the utility model.

[0025] Figure 3 This is a schematic diagram of the side section structure of an observation device for cell exhaustion research proposed by the utility model.

[0026] Figure 4 The utility model provides an observation device for cell exhaustion research Figure 3 Enlarged structural diagram at A in the middle.

[0027] Figure 5 This is a schematic diagram of the front section structure of a threaded barrel of an observation device for cell exhaustion research proposed by the utility model.

[0028] In the attached figure: 1. mounting frame; 2. object carrier; 3. placement frame; 4. microscope body; 5. lead screw; 6. threaded cylinder; 7. connecting rod; 8. pressure plate; 9. light hole; 10. reflector; 11. limit slider; 12. mounting frame; 13. motor; 14. threaded rod; 15. threaded block; 16. connecting frame; 17. electric push rod; 18. guide slider; 19. mounting slider; 20. controller. DETAILED DESCRIPTION

[0029] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments.

[0030] Reference Figure 1-Figure 5 An observation device for cell exhaustion research includes a mounting frame 1 and a carrier seat 2. A placement frame 3 is fixedly mounted on the front of the mounting frame 1, a microscope body 4 is mounted inside the placement frame 3, a controller 20 is arranged on the right side of the mounting frame 1, a fine-tuning mechanism is arranged between the mounting frame 1 and the carrier seat 2, and a clamping mechanism is arranged on the surface of the carrier seat 2.

[0031] The clamping mechanism includes a storage groove opened on the upper surface of the carrier 2, and a rotating opening penetrating into the interior of the storage groove is opened on the lower surface of the carrier 2. The inner wall of the rotating opening is rotatably connected to a screw rod 5 extending into the interior of the storage groove, and the surface of the screw rod 5 is threadedly connected to a threaded tube 6, and the upper end of the threaded tube 6 is fixedly connected to a connecting rod 7, and the front side of the connecting rod 7 is fixedly connected to two symmetrical pressure plates 8.

[0032] A light hole 9 is formed through the surface of the object carrier 2 , and a reflector 10 corresponding to the position of the light hole 9 is mounted on the lower surface of the object carrier 2 via an L-shaped frame.

[0033] A flexible cushion layer is disposed on the lower surface of the pressing plate 8 . The flexible cushion layer is made of a silicone material. The flexible cushion layer can protect the glass slide sample when the pressing plate 8 presses the glass slide sample.

[0034] Reference Figure 5 In a preferred embodiment, both side surfaces of the threaded barrel 6 are provided with limit sliders 11, and both side inner walls of the receiving groove are provided with limit sliding grooves for the limit sliders 11 to slide.

[0035] Under the guidance of the limit slider 11 , the threaded barrel 6 can be moved up and down in a directional manner through the rotation of the screw rod 5 .

[0036] Reference Figure 2 and Figure 3 In a preferred embodiment, the fine-tuning mechanism includes a mounting frame 12 embedded in the front of the mounting frame 1, a motor 13 is fixedly installed on the right end of the mounting frame 12, the output shaft of the motor 13 extends to the interior of the mounting frame 12 and is fixedly connected to a threaded rod 14, a threaded block 15 is threadedly connected to the surface of the threaded rod 14, a connecting frame 16 is fixedly installed on the front of the threaded block 15, an electric push rod 17 is embedded in the inner rear wall of the connecting frame 16, and the telescopic end of the electric push rod 17 is fixedly connected to the back of the object carrier 2.

[0037] By configuring the motor 13 and the electric push rod 17 , the lateral and longitudinal positions of the object carrier 2 can be adjusted respectively.

[0038] The motor 13 and the electric push rod 17 are both electrically connected to the controller 20 .

[0039] Reference Figure 2 In a preferred embodiment, a guide slider 18 is provided on the back of the threaded block 15 , and a guide groove for the guide slider 18 to slide is provided on the inner rear wall of the mounting frame 12 .

[0040] By providing the guide slide block 18 , the threaded block 15 can be moved leftward or rightward by rotating the threaded rod 14 .

[0041] Reference Figure 2 In a preferred embodiment, mounting slide blocks 19 are provided on both side surfaces of the object carrier 2 , and mounting grooves adapted to the mounting slide blocks 19 are provided on both side inner walls of the connecting frame 16 .

[0042] By installing the sliding block 19 , the object carrier 2 can be provided with an auxiliary load-bearing effect, thereby preventing all gravity from acting on the electric push rod 17 .

[0043] Working principle: place the glass slide sample on the sample holder 2, rotate the screw rod 5, and the threaded tube 6 drives the connecting rod 7 and the pressure plate 8 to move downward under the rotation of the screw rod 5, until the pressure plate 8 presses the glass slide sample against the sample holder 2, and then fixes it. When it is necessary to fine-tune the position of the glass slide sample according to observation needs, the controller 20 controls the motor 13 and the electric push rod 17 to operate respectively. The operation of the motor 13 drives the threaded rod 14 to rotate, and the threaded block 15 drives the connecting frame 16 and the sample holder 2 to move left and right through the rotation of the threaded rod 14, so that the lateral position of the glass slide sample can be adjusted. At the same time, the operation of the electric push rod 17 pushes the sample holder 2 to move back and forth in the connecting frame 16, so that the longitudinal position of the glass slide sample can be adjusted.

[0044] The above is only a preferred specific implementation of the utility model, but the protection scope of the utility model is not limited to this. The replacement can be a replacement of part of the structure, device, method step, or a complete technical solution. Equivalent replacement or change based on the technical solution of the utility model and its utility model concept should be included in the protection scope of the utility model.

Claims

1. An observation device for cell exhaustion research, characterized in that: The invention comprises a mounting frame (1) and an object carrier (2), wherein a placement frame (3) is fixedly mounted on the front of the mounting frame (1), a microscope body (4) is mounted inside the placement frame (3), a controller (20) is arranged on the right side of the mounting frame (1), a fine adjustment mechanism is arranged between the mounting frame (1) and the object carrier (2), and a clamping mechanism is arranged on the surface of the object carrier (2); The clamping mechanism comprises a receiving groove formed on the upper surface of the object carrier (2); a rotating opening penetrating into the interior of the receiving groove is formed on the lower surface of the object carrier (2); a screw rod (5) extending into the interior of the receiving groove is rotatably connected to the inner wall of the rotating opening; a threaded cylinder (6) is threadedly connected to the surface of the screw rod (5); a connecting rod (7) is fixedly connected to the upper end of the threaded cylinder (6); and two symmetrical pressing plates (8) are fixedly connected to the front of the connecting rod (7); The fine adjustment mechanism comprises a mounting frame (12) embedded in the front of the mounting frame (1); a motor (13) is fixedly mounted on the right end of the mounting frame (12); an output shaft of the motor (13) extends into the interior of the mounting frame (12) and is fixedly connected to a threaded rod (14); a threaded block (15) is threadedly connected to the surface of the threaded rod (14); a connecting frame (16) is fixedly mounted on the front of the threaded block (15); an electric push rod (17) is embedded in the inner rear wall of the connecting frame (16); and a telescopic end of the electric push rod (17) is fixedly connected to the back of the object carrier (2).

2. The observation device for cell exhaustion research according to claim 1, characterized in that: A light-through hole (9) is formed through the surface of the object carrier (2), and a reflector (10) corresponding to the position of the light-through hole (9) is mounted on the lower surface of the object carrier (2) via an L-shaped frame.

3. The observation device for cell exhaustion research according to claim 2, characterized in that: The two side surfaces of the threaded cylinder (6) are both provided with limit slide blocks (11), and the two side inner walls of the storage groove are both provided with limit slide grooves for the limit slide blocks (11) to slide.

4. The observation device for cell exhaustion research according to claim 3, characterized in that: The lower surface of the pressing plate (8) is provided with a flexible cushion layer, and the flexible cushion layer is made of silica gel material.

5. The observation device for cell exhaustion research according to claim 4, characterized in that: A guide slide block (18) is arranged on the back of the threaded block (15), and a guide slide groove for the guide slide block (18) to slide is provided on the inner rear wall of the installation frame (12).

6. The observation device for cell exhaustion research according to claim 5, characterized in that: Both side surfaces of the object carrier (2) are provided with mounting slide blocks (19), and both side inner walls of the connection frame (16) are provided with mounting slide grooves adapted to the mounting slide blocks (19).

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