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Use of substance formaldehyde in preparing medicament for coccidiosis of animal

A technology for animal coccidiosis and formaldehyde, applied to medical preparations containing active ingredients, anti-infective drugs, drug combinations, etc., can solve problems such as harmful coccidiosis and DNA damage

Inactive Publication Date: 2011-06-22
关中田
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] 2. There are many types of coccidia, and no drug has an ideal effect on all types of coccidia. "Drug-resistant coccidia develop resistance after contact with drugs..., coccidia have a wide range of drug resistance
[0005] 3. The following conditions are well known: In order to avoid the harm of drug residues to human health and the drug resistance of coccidia, several vaccines for preventing coccidiosis have been developed, but each vaccine is only for a certain coccidiosis Prevention is specific and ineffective against other species of coccidiosis
[0006] 2. The prior art related to the practicability of the substance formaldehyde as an anticoccidial drug;
""Using various mammalian test results in vitro, it is proved that formaldehyde has the effect of inducing gene mutations in mammalian cells, and has a damaging effect on DNA,... However, the test results of whole animals are contrary, and the main reason may be that formaldehyde is metabolized in vivo Fast, except for organs that are directly exposed to formaldehyde (such as the nose and organs), keep away from tissues that are in contact with organs, and are rarely directly affected by formaldehyde

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 4

[0093] It can be seen from the above table that the anticoccidial index of group A using formaldehyde is very effective and significantly stronger than that of group B using diclazuril; according to the above calculation formula of Merck, the anticoccidial index of formaldehyde is excellent of. Reference Example 4: Comparative test on the effect of the substance formaldehyde and the use of sulfamethazine in the treatment of calf coccidia

[0094] From August 7th to August 16th, 2007, with the cooperation of the animal laboratory of Zhaozhou Institute of Animal Husbandry and Veterinary Medicine, Daqing City, we conducted a test on the effect of formaldehyde and the traditional drug sulfamethazine on the prevention and treatment of coccidia in beef cattle .

[0095] 4.1 Materials and methods

[0096] 4.1.1 Test cattle

[0097] Among the 541 fattening cattle raised by Tan Chunyu in Taiji Village, Wanbao Township, Zhaozhou County, 42 calves aged 2-3 months had bloody feces, whi...

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PUM

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Abstract

The invention relates to novel application of preventing and treating mammalian coccidiosis by of the prepared formaldehyde in the field of animal drugs. The invention provides and proves that application of the formaldehyde has certain effects, advantages and the like in preventing and treating the mammalian coccidiosis, thereby further providing a medicine prepared by the formaldehyde and used for preventing and treating the mammalian coccidiosis.

Description

【Technical field】 [0001] The invention relates to a new application of a substance in the preparation of animal medicines. In particular, it relates to the use of formaldehyde in the preparation of medicines for preventing and treating coccidiosis in animals. 【Background technique】 [0002] 1. The prior art about animal coccidiosis and its control drugs: [0003] 1. Coccidiosis is a common disease that can be seen in a variety of animals in the production of livestock and poultry. The clinical manifestations are mainly hemorrhagic enteritis, bloody dysentery, high morbidity and mortality of young livestock and poultry (chicks, etc.). Coccidia are widely parasitic in the digestive tract of various poultry, livestock, wild animals and aquatic animals, and its high incidence can bring serious economic losses to the breeding industry. According to incomplete statistics, in the chicken industry, the chicken coccidiosis incidence rate is 50%-70%, the mortality rate is 20%-30%, a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61P33/02A61K31/115A61K31/765
Inventor 关中田
Owner 关中田
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